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Glycoside Hydrolase Family 136

Activities in FamilyLacto-N-biosidase (Lewis antigen a/b specificity) (EC 3.2.1.-);
Lacto-N-biosidase (EC 3.2.1.140);
Mechanism Retaining e
3D Structure Statusparallel β-helix
Catalytic Nucleophile/BaseAsp
Catalytic Proton DonorAsp
NoteCreated after Yamada et al. (2017) Cell Chem Biol 24:515-524 (PMID=28392148)
External resourcesCAZypedia;
Statistics GenBank accession (1161); Uniprot accession (7); PDB accession (7); 3D entries (4); cryst (0)
Summary
Download GH136 (1200) Taxonomic display Structure (4) Characterized (7)
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Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 ISN59_06595   Enterococcus faecalis AR_0780 UEP64413.1    
 DR75_1076   Enterococcus faecalis ATCC 29212 AIL05723.1    
 GIR35_00135   Enterococcus faecalis BFFF11 QGM89718.1    
 DOU31_04365   Enterococcus faecalis C25 QCX14004.1    
 DOU32_10035   Enterococcus faecalis C54 QCX17886.1    
 BZG32_10695   Enterococcus faecalis CLB21560 AQL54136.1    
 EFD32_1817   Enterococcus faecalis D32 AFO44703.1    
 DENG_02280   Enterococcus faecalis DENG1 AHI41186.1    
 FLL49_09500   Enterococcus faecalis DM01 QDJ06676.1    
 K4200_09500   Enterococcus faecalis E006 QZT48921.1    
 K4752_04650   Enterococcus faecalis E006-TC QZK93927.1    
 LM510_10375   Enterococcus faecalis E509 UER74092.1    
 LM505_04195   Enterococcus faecalis E512 UER70157.1    
 LM505_10440   Enterococcus faecalis E512 UER68581.1    
 LM511_09055   Enterococcus faecalis E512-TC1 UER76681.1    
 LM512_09055   Enterococcus faecalis E512-TC2 UER71332.1    
 LM507_12245   Enterococcus faecalis E533 UFG25266.1    
 LM507_03295   Enterococcus faecalis E533 UFG26396.1    
 H8446_09290   Enterococcus faecalis EF-2001 QTI51982.1    
 LIT97_11155   Enterococcus faecalis EFS108 UDM46386.1    
 LIT95_01070   Enterococcus faecalis EFS17 UDM41384.1    
 LIT96_11180   Enterococcus faecalis EFS36 UDM43347.1    
 EGM183_08800   Enterococcus faecalis EGM183 QOG34219.1    
 G7X26_09325   Enterococcus faecalis ES-1 QIJ68584.1    
 LNB41_04210   Enterococcus faecalis Fac74 UER80942.1    
 LNB41_10470   Enterococcus faecalis Fac74 UER79363.1    
 C9432_10840   Enterococcus faecalis FC QCJ67304.1    
 CEQ02_11055   Enterococcus faecalis FDAARGOS_324 AVR92358.1    
 EGX75_09800   Enterococcus faecalis FDAARGOS_528 AYZ07512.1    
 FIU23_06170   Enterococcus faecalis FDAARGOS_611 QDD47482.1    
 FHO10_05280   Enterococcus faecalis HA-1 QDB76050.1    
 F9293_05700   Enterococcus faecalis JY32 QHT40395.1    
 EFK4_17690   Enterococcus faecalis K-4 BDC76866.1    
 ADH73_04490   Enterococcus faecalis KB1 ASU25406.1
QQR12610.1		    
 KUB3006_C19000   Enterococcus faecalis KUB3006 BBD25474.1    
 KUB3007_C18990   Enterococcus faecalis KUB3007 BBD28515.1    
 JO410_09515   Enterococcus faecalis L11 QRG96833.1    
 JZP77_04315   Enterococcus faecalis L13 QSO20516.1    
 F1M88_10125   Enterococcus faecalis L14 QHN67989.1    
 CGZ46_10230   Enterococcus faecalis L15 QFY93056.1    
 JZP80_04030   Enterococcus faecalis L16 QSO27259.1    
 JZP76_09375   Enterococcus faecalis L17 QUE58519.1    
 JZP79_09165   Enterococcus faecalis L18 QSO28353.1    
 JZP78_03955   Enterococcus faecalis L21 QUE57411.1    
 FOA09_09795   Enterococcus faecalis L8 QFY95935.1    
 BMT03_09035   Enterococcus faecalis L9 APC56356.1    
 NCTC8745_01754   Enterococcus faecalis NCTC8745 VEE96859.1    
 KVY10_08470   Enterococcus faecalis NS2 QXN79520.1    
 CVT43_09305   Enterococcus faecalis OG1RF AZV34515.1
AEA94456.1		    
 CVT44_09305   Enterococcus faecalis OG1RF-SagA AZV97359.1    
 EYB36_11675   Enterococcus faecalis R712 QGI56445.1    
 FOV01_04410   Enterococcus faecalis SCAID PHRX1-2018 QDR51955.1    
 H9Q64_10100   Enterococcus faecalis SF28073 QNP36823.1    
 E7T04_09310   Enterococcus faecalis SGAir0397 QCR01853.1    
 A6B47_14315   Enterococcus faecalis sorialis ARV05068.1    
 A6B47_09725   Enterococcus faecalis sorialis ARV04112.1    
 KUO14_09855   Enterococcus faecalis SY-1 QXL80875.1    
 JG557_04640   Enterococcus faecalis T90-1 QQV86994.1    
 GRB94_10185   Enterococcus faecalis TH4125 QJC67993.1    
 DTO64_10490   Enterococcus faecalis TY1 AXG88960.1    
 HKK65_04965   Enterococcus faecalis UM001B QOL17747.1    
 EF_2229   Enterococcus faecalis V583 AAO81960.1    
 EFW11_1707   Enterococcus faecalis W11 BAV36946.1    
 KW861_16695   Enterococcus gallinarum fecal_iso1 UXA04012.1    
 EGCR1_00075   Enterococcus gilvus CR1 AXG37184.1    
 HU257_03305   Enterococcus hirae 13152 QKX70716.1    
 HU255_03195   Enterococcus hirae 708 QKX68177.1    
 N7K39_09690 (fragment)   Enterococcus raffinosus Er676 UXJ94515.1    
 J9537_01985   Enterococcus raffinosus F162_2 QXJ59585.1    
 N4S13_09380 (fragment)   Enterococcus raffinosus HG-5 UXC24323.1    
 FE005_16765   Enterococcus sp. M190262 QCT93619.1    
 MTP05_18000   Enterococcus sp. PLM3 BDH65615.1    
 G7061_00570   Erysipelothrix sp. HDW6B QIK85194.1    
 lacto-N-biosidase (ErLnb136; HMPREF0373_02965) 3.2.1.140 Eubacterium ramulus ATCC 29099 ERK42296.1 U2PDT9 6KQS[A]
6KQT[A]
 NQ558_01015   Eubacterium ventriosum ATCC 27560 UWP36181.1    
 FLA_5509   Filimonas lacunae NBRC 104114 BAV09460.1    
 N510_001926 (fragment)   Firmicutes bacterium ASF500 USF26992.1    
 KM029_23975   Flammeovirga kamogawensis YS10 QWG09665.1    
 KM029_22025   Flammeovirga kamogawensis YS10 QWG09286.1    
 KM029_22175   Flammeovirga kamogawensis YS10 QWG09316.1    
 KM029_23520   Flammeovirga kamogawensis YS10 QWG09581.1    
 KM029_26585   Flammeovirga kamogawensis YS10 QWG10543.1    
 KM029_21955   Flammeovirga kamogawensis YS10 QWG09272.1    
 KM029_21880   Flammeovirga kamogawensis YS10 QWG09258.1    
 KM029_20035   Flammeovirga kamogawensis YS10 QWG09973.1    
 KM029_21350   Flammeovirga kamogawensis YS10 QWG10231.1    
 KM029_22190   Flammeovirga kamogawensis YS10 QWG09318.1    
 KM029_23530   Flammeovirga kamogawensis YS10 QWG09583.1    
 KM029_25510   Flammeovirga kamogawensis YS10 QWG10744.1    
 KM029_22845   Flammeovirga kamogawensis YS10 QWG09449.1    
 EI427_24315   Flammeovirga pectinis L12M1 AZQ65341.1    
 EI427_21205   Flammeovirga pectinis L12M1 AZQ64745.1    
 EI427_21470   Flammeovirga pectinis L12M1 AZQ64797.1    
 EI427_22775   Flammeovirga pectinis L12M1 AZQ65048.1    
 EI427_21215   Flammeovirga pectinis L12M1 AZQ64747.1    
 EI427_21915   Flammeovirga pectinis L12M1 AZQ64885.1    
 EI427_20755   Flammeovirga pectinis L12M1 AZQ64657.1    
 EI427_21485   Flammeovirga pectinis L12M1 AZQ64800.1    
 EI427_21295   Flammeovirga pectinis L12M1 AZQ64763.1    
 EI427_22785   Flammeovirga pectinis L12M1 AZQ65050.1    
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