Glycoside Hydrolase Family 136

Activities in FamilyLacto-N-biosidase (Lewis antigen a/b specificity) (EC 3.2.1.-);
Lacto-N-biosidase (EC 3.2.1.140);
Mechanism Retaining e
3D Structure Statusparallel β-helix
Catalytic Nucleophile/BaseAsp
Catalytic Proton DonorAsp
NoteCreated after Yamada et al. (2017) Cell Chem Biol 24:515-524 (PMID=28392148)
External resourcesCAZypedia;
Statistics GenBank accession (1161); Uniprot accession (7); PDB accession (7); 3D entries (4); cryst (0)
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Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 SLCG_0549   Streptomyces lincolnensis LC-G AXG51704.1    
 SLINC_0709   Streptomyces lincolnensis NRRL 2936 ANS62933.1    
 SLINC_0556   Streptomyces lincolnensis NRRL 2936 ANS62780.1    
 LGI35_15150   Streptomyces longhuiensis BH-MK-02 UDL99522.1    
 LGI35_33405   Streptomyces longhuiensis BH-MK-02 UDM02825.1    
 T261_0009   Streptomyces sp. A02 AJT61702.1    
 LJ741_00015   Streptomyces lydicus M01 UEG89069.1    
 GO605_16980   Streptomyces murinus CR-43 UWW92348.1    
 ME763_00580   Streptomyces murinus JS029 WDO04269.1    
 ME763_00585 (fragment)   Streptomyces murinus JS029 WDO10747.1    
 HEK616_39390 (fragment)   Streptomyces nigrescens HEK616 BDM70452.1    
 BBN63_03845   Streptomyces niveus SCSIO 3406 AQU65507.1    
 DVK44_33255   Streptomyces paludis GSSD-12 AXG81790.1    
 OGH68_00715   Streptomyces peucetius NA0869 UYQ60140.1    
 CGZ69_34390   Streptomyces peucetius subsp. caesius ATCC 27952 ATW53044.1    
 F9278_44015   Streptomyces phaeolivaceus GY16 QFR01995.1    
 LIV37_48675 (fragment)   Streptomyces rapamycinicus NRRL 5491 UTP36475.1    
 RGF97_32520   Streptomyces roseicoloratus T14 WMX48581.1    
 F0345_27975   Streptomyces rutgersensis NBH77 QNE84470.1    
 HUT11_06110   Streptomyces seoulensis A01 QKW25741.1    
 CGL27_02995   Streptomyces sp. 11-1-2 ASQ92253.1    
 P8T65_32480   Streptomyces sp. 11x1 WNZ11804.1    
 SAMN06272775_1385   Streptomyces sp. 2323.1 SOE10331.1    
 ASR50_07540 (fragment)   Streptomyces sp. 4F ALV49267.1    
 IOD14_25770   Streptomyces sp. A2-16 QUC59888.1    
 P8A21_31480   Streptomyces sp. Alt1 WLQ51735.1    
 P8A21_37015   Streptomyces sp. Alt1 WLQ52749.1    
 P8A21_36960   Streptomyces sp. Alt1 WLQ52741.1    
 P8A21_24360   Streptomyces sp. Alt1 WLQ50414.1    
 P8A19_16310   Streptomyces sp. Alt2 WLQ56918.1    
 P8A19_03095   Streptomyces sp. Alt2 WLQ54491.1    
 P8A19_08680   Streptomyces sp. Alt2 WLQ55511.1    
 P8A20_00595   Streptomyces sp. Alt3 WLQ62175.1    
 PZB77_06530   Streptomyces sp. AM 2-1-1 WEH39204.1    
 RPQ02_34670   Streptomyces sp. AM8-1-1 WNO68598.1    
 CVT30_45350   Streptomyces sp. AMCC400023 UJV46129.1    
 JIX56_02045   Streptomyces sp. CA-210063 UUU28772.1    
 HXS80_00195   Streptomyces sp. CB04723 QLG36101.1    
 AS200_02130   Streptomyces sp. CdTB01 ALV31008.1    
 NNW99_34065   Streptomyces sp. CRCS-T-1 UUA17896.1    
 NNW98_34180   Streptomyces sp. CRLD-Y-1 UUA10289.1    
 JIX55_45115   Streptomyces sp. DSM 40750 UUU26830.1    
 JIX55_41790   Streptomyces sp. DSM 40750 UUU26235.1    
 JIX55_08340   Streptomyces sp. DSM 40750 UUU20313.1    
 KK483_33860   Streptomyces sp. FIT100 UUN30768.1    
 KK483_22755   Streptomyces sp. FIT100 UUN28889.1    
 Q7C01_22160   Streptomyces sp. FXY-T5 WMD06913.1    
 WJ438_05935 (fragment)   Streptomyces sp. GD-15H WYB34735.1    
 GR129_33465   Streptomyces sp. HF10 QHC32949.1    
 Q3Y68_36530   Streptomyces sp. HUAS CX7 WKX23265.1    
 R2D22_33145   Streptomyces sp. HUAS YS2 WOX25970.1    
 R2D22_01880   Streptomyces sp. HUAS YS2 WOX20204.1    
 RLT58_13985   Streptomyces sp. ITFR-16 WNI22967.1    
 RKE30_16280   Streptomyces sp. Li-HN-5-11 WNM31852.1    
 RKE30_15935   Streptomyces sp. Li-HN-5-11 WNM31790.1    
 H3V39_33325   Streptomyces sp. M54 QSS95381.1    
 ABC-type xylose transport system periplasmic component   Streptomyces sp. MMG1522 AGZ94150.1    
 P8A18_27610   Streptomyces sp. Mut1 WLQ36966.1    
 R2B38_21095   Streptomyces sp. N50 WOX11165.1    
 HUT18_18495   Streptomyces sp. NA04227 QKW08076.1    
 HUT18_17395   Streptomyces sp. NA04227 QKW07899.1    
 HUT18_28525   Streptomyces sp. NA04227 QKW09768.1    
 JIW86_04940 (fragment)   Streptomyces sp. NBC00162 UUU38256.1    
 JIW86_07535   Streptomyces sp. NBC00162 UUU38680.1    
 OG290_31555   Streptomyces sp. NBC_01423 WUX94043.1    
 OG574_14355   Streptomyces sp. NBC_01445 WSE04434.1    
 OG574_32195   Streptomyces sp. NBC_01445 WSE07584.1    
 OIU81_07595   Streptomyces sp. NBC_01454 WUW69703.1    
 C6376_31140   Streptomyces sp. P3 AVV45175.1    
 C6376_36000   Streptomyces sp. P3 AVV45972.1    
 V2W30_02570   Streptomyces sp. Q6 WWQ62355.1    
 HYQ63_42815   Streptomyces sp. Rer75 QLH26520.1    
 SJI45_29130   Streptomyces sp. S399 WPR54475.1    
 SSPS47_31040 (fragment)   Streptomyces sp. S4.7 QHY99546.1    
 A8713_30140   Streptomyces sp. SAT1 ANH94908.1    
 C8250_037160   Streptomyces sp. So13.3 QNA76756.1    
 PBV52_02480   Streptomyces sp. T12 WDF35742.1    
 WBG99_31680   Streptomyces sp. TG1A-60 WXC24369.1    
 WBG99_16390 (fragment)   Streptomyces sp. TG1A-60 WXC21825.1    
 SAMN05216371_0740   Streptomyces sp. TLI_053 SDS84896.1    
 KE639_00027   Streptomyces sp. V17-9 QUW88854.1    
 DMB38_08340   Streptomyces sp. WAC 06738 AZM45837.1    
 O7599_29095   Streptomyces sp. WMMC500 WBB59584.1    
 QHG49_32800   Streptomyces sp. WP-1 WKE73443.1    
 StreXyl84_03100   Streptomyces sp. Xyl84 BFD80909.1    
 KME66_33090   Streptomyces sp. YPW6 QWQ45284.1    
 SSPO_094840   Streptomyces sporoclivatus NBRC 100767 BBJ46766.1    
 LDH80_04355   Streptomyces tanashiensis Kala UZX19994.1    
 ORF   Streptomyces tendae Tu 4042 CAM34334.1    
 MMF93_01540   Streptomyces tubbatahanensis DSD3025 UNS95295.1    
 ORF   Streptomyces tumemacerans JCM 5050 UUL71894.1    
 DEJ45_07255   Streptomyces venezuelae ATCC 10595 QES12215.1    
 DEJ43_30210   Streptomyces venezuelae ATCC 10712 QES03943.1    
 SVEN_6017   Streptomyces venezuelae ATCC 10712 CCA59303.1    
 DEJ48_21655   Streptomyces venezuelae ATCC 14584 QES35676.1    
 DEJ46_33440   Streptomyces venezuelae ATCC 15068 QES23426.1    
 DEJ44_28245   Streptomyces venezuelae ATCC 21113 QES09132.1    
 SVTN_02020   Streptomyces vietnamensis GIM4.0001 AJF69466.1    
 IAG42_07680   Streptomyces xanthii CRXT-Y-14 QNS03523.1    
 IAG42_33575   Streptomyces xanthii CRXT-Y-14 QNS09081.1    
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