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Glycoside Hydrolase Family 136

Activities in FamilyLacto-N-biosidase (Lewis antigen a/b specificity) (EC 3.2.1.-);
Lacto-N-biosidase (EC 3.2.1.140);
Mechanism Retaining e
3D Structure Statusparallel β-helix
Catalytic Nucleophile/BaseAsp
Catalytic Proton DonorAsp
NoteCreated after Yamada et al. (2017) Cell Chem Biol 24:515-524 (PMID=28392148)
External resourcesCAZypedia;
Statistics GenBank accession (1161); Uniprot accession (7); PDB accession (7); 3D entries (4); cryst (0)
Summary
Download GH136 (1200) Taxonomic display Structure (4) Characterized (7)
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Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 Athai_33410   Actinocatenispora thailandica NBRC 105041 BCJ35838.1    
 U6G28_02135   Actinomycetaceae bacterium MB13-C1-2 WRS30513.1    
 SAMN04489716_9478   Actinoplanes derwentensis DSM 43941 SDT81061.1    
 Q0Z83_013580   Actinoplanes sichuanensis 03-723 BEL03167.1    
 K1X11_018065   Opitutus sp. WL0086 WRQ86722.1    
 HG15A2_24970   Adhaeretor mobilis HG15A2 QDS99205.1    
 HG15A2_42570   Adhaeretor mobilis HG15A2 QDT00915.1    
 HG15A2_42580   Adhaeretor mobilis HG15A2 QDT00916.1    
 HG15A2_24950   Adhaeretor mobilis HG15A2 QDS99203.1    
 V3C14_18185   Agathobacter rectalis DFI.5.28 WVP55065.1    
 V3C14_14295   Agathobacter rectalis DFI.5.28 WVP54336.1    
 ERE_09580   Agathobacter rectalis M104/1 CBK93002.1    
 MUN74_12285 (fragment)   Agromyces sp. H17E-10 UOQ88070.1    
 HZ994_13805   Akkermansiaceae bacterium AJA081-3 QTN33342.1    
 GYM62_02170   Algoriphagus sp. NBT04N3 QYH37663.1    
 NQ519_08270   Alistipes senegalensis JC50 UWN63773.1    
 NQ519_07165   Alistipes senegalensis JC50 UWN66607.1    
 H7849_16695   Alloacidobacterium dinghuense 4Y35 QNI30750.1    
 G6N82_04625   Altererythrobacter sp. BO-6 QIG53524.1    
 ISP_008075   Amycolatopsis mediterranei ISP5501 UZF74551.1    
 ISP_001309   Amycolatopsis mediterranei ISP5501 UZF68252.1    
 B737_5298   Amycolatopsis mediterranei RB AGT85962.1    
 B737_7714   Amycolatopsis mediterranei RB AGT88375.1    
 RAM_27335   Amycolatopsis mediterranei S699 AEK43944.1    
 AMES_5298   Amycolatopsis mediterranei S699 AFO78834.1    
 AMES_7714   Amycolatopsis mediterranei S699 AEK46516.1
AFO81247.1		    
 AMED_7830   Amycolatopsis mediterranei U32 ADJ49538.1    
 AMED_5363   Amycolatopsis mediterranei U32 ADJ47123.1    
 MUY22_08525   Amycolatopsis sp. WQ 127309 UOZ08305.1    
 QA584_19330   Anaerocolumna sp. AGMB13025 WFR55751.1    
 bsdcttw_29920   Anaerocolumna sp. CTTW BCJ99951.1    
 FK178_09830   Antarcticibacterium arcticum PAMC 28998 QED38005.1    
 FHG64_06930   Antarcticibacterium flavum KCTC 52984 QCY69156.1    
 LZ575_11680 (fragment)   Antarcticibacterium sp. 1MA-6-2 UJH89717.1    
 LZ575_20540 (fragment)   Antarcticibacterium sp. 1MA-6-2 UJH91027.1    
 LZ575_20545 (fragment)   Antarcticibacterium sp. 1MA-6-2 UJH91028.1    
 AQPE_1272   Aquipluma nitroreducens MeG22 BBE17123.1    
 MB46_06440   Arthrobacter sp. A3 ALV45198.1    
 F8G81_05345   Arthrobacter sp. CDRTa11 UZX02107.1    
 AYX22_06360   Arthrobacter sp. D5-1 QSZ48064.1    
 NtRootA1_10830   Arthrobacter sp. NtRootA1 BCW04945.1    
 ART_3610   Arthrobacter sp. PAMC 25486 AIY03209.1    
 StoSoilA2_11530   Arthrobacter sp. StoSoilA2 BCW35097.1    
 StoSoilB13_34240   Arthrobacter sp. StoSoilB13 BCW51082.1    
 StoSoilB5_11180   Arthrobacter sp. StoSoilB5 BCW43934.1    
 P9849_09005   Arthrobacter sp. Y-9 WFR82720.1    
 CGK93_06055   Arthrobacter sp. YN ASN19302.1    
 G8758_06255   Arthrobacter woluwensis QTS QTF71648.1    
 H1Q64_28320   Azospirillum brasilense 2020WEIHUA_K UKJ76984.1    
 D9623_22435   Azospirillum brasilense Cd QEL99211.1    
 D3093_25660   Azospirillum brasilense MTCC4035 QCN98607.1    
 D9621_22165   Azospirillum brasilense Sp 7 QEL92896.1    
 FAY30_01690   Bacillus sp. S3 QCJ40719.1    
 RJT08_11935   Bacteroides caccae H-1617 WOG09983.1    
 NXW88_10220   Bacteroides cellulosilyticus BFG-371 UVP53217.1    
 NXW88_10225   Bacteroides cellulosilyticus BFG-371 UVP53218.1    
 NXW88_10565   Bacteroides cellulosilyticus BFG-371 UVP53283.1    
 INE78_00144   Bacteroides cellulosilyticus CL06T03C01 QUT88191.1    
 INE78_00143   Bacteroides cellulosilyticus CL06T03C01 QUT88190.1    
 INE78_04335   Bacteroides cellulosilyticus CL06T03C01 QUT92317.1    
 NWT25_10035   Bacteroides cellulosilyticus PL2022 UWZ91532.1    
 NWT25_10305   Bacteroides cellulosilyticus PL2022 UWZ91583.1    
 NWT25_10045   Bacteroides cellulosilyticus PL2022 UWZ91534.1    
 BcellWH2_03604   Bacteroides cellulosilyticus WH2 ALJ60827.1    
 BcellWH2_03668   Bacteroides cellulosilyticus WH2 ALJ60891.1    
 INE88_01453   Bacteroides eggerthii CL11T00C20 QUT44652.1    
 INE88_01455   Bacteroides eggerthii CL11T00C20 QUT44654.1    
 NXX60_10080 (fragment)   Bacteroides thetaiotaomicron BFG-148 UVQ24181.1    
 NXX60_10095   Bacteroides thetaiotaomicron BFG-148 UVQ24183.1    
 NXX60_12725   Bacteroides thetaiotaomicron BFG-148 UVQ24542.1    
 NXX60_10085 (fragment)   Bacteroides thetaiotaomicron BFG-148 UVQ24182.1    
 NXX60_12720   Bacteroides thetaiotaomicron BFG-148 UVQ24541.1    
 KHO74_00636   Bacteroides thetaiotaomicron CL15T119C52 QZU84682.1    
 KHO74_00637   Bacteroides thetaiotaomicron CL15T119C52 QZU84683.1    
 KHO73_00629   Bacteroides thetaiotaomicron CL15T12C11 QZU79259.1    
 KHO73_00628   Bacteroides thetaiotaomicron CL15T12C11 QZU79258.1    
 V3C11_24505   Bacteroides thetaiotaomicron DFI.6.40 WVP66925.1    
 V3C11_24510   Bacteroides thetaiotaomicron DFI.6.40 WVP66926.1    
 BatF92_05220   Bacteroides thetaiotaomicron F9-2 BCA48580.1    
 BatF92_05230   Bacteroides thetaiotaomicron F9-2 BCA48581.1    
 BatF92_09710   Bacteroides thetaiotaomicron F9-2 BCA49029.1    
 BatF92_09700   Bacteroides thetaiotaomicron F9-2 BCA49028.1    
 KQP56_05630   Bacteroides thetaiotaomicron VPI-3164 UYU96979.1    
 KQP56_05635   Bacteroides thetaiotaomicron VPI-3164 UYU96980.1    
 KQP68_20855   Bacteroides thetaiotaomicron WAL8669 UYU65991.1    
 KQP68_20850   Bacteroides thetaiotaomicron WAL8669 UYU65990.1    
 NXX35_10750   Bacteroides xylanisolvens BFG-566 UVR75861.1    
 NXX35_10760   Bacteroides xylanisolvens BFG-566 UVR75863.1    
 BA20089_08545   Bifidobacterium asteroides DSM 20089 ATO42142.1    
 BAST_0140   Bifidobacterium asteroides PRL2011 AFU70744.1    
 BBBF_0451   Bifidobacterium bifidum ATCC 29521 = JCM 1255 = DSM 20456 BAQ97658.1    
 RY70_539   Bifidobacterium bifidum BF3 ALE10905.1    
 BBB_0436   Bifidobacterium bifidum BGN4 AFL04031.1    
 CNCMI4319_0437   Bifidobacterium bifidum CNCM I-4319 QTQ17888.1    
 BBJK_02171   Bifidobacterium bifidum LMG 13195 JCM 7004 BBA48469.1    
 VZN89_04815   Bifidobacterium bifidum lw02 WXX24932.1    
 NCTC13001_01805   Bifidobacterium bifidum NCTC13001 VEG19581.1    
 BBPR_0460   Bifidobacterium bifidum PRL2010 ADP35567.1    
 BBIF_0483   Bifidobacterium bifidum S17 ADO52688.1    
 BBTM_02523   Bifidobacterium bifidum TMC 3115 BBA56588.1    
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