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Glycoside Hydrolase Family 136

Activities in FamilyLacto-N-biosidase (Lewis antigen a/b specificity) (EC 3.2.1.-);
Lacto-N-biosidase (EC 3.2.1.140);
Mechanism Retaining e
3D Structure Statusparallel β-helix
Catalytic Nucleophile/BaseAsp
Catalytic Proton DonorAsp
NoteCreated after Yamada et al. (2017) Cell Chem Biol 24:515-524 (PMID=28392148)
External resourcesCAZypedia;
Statistics GenBank accession (1161); Uniprot accession (7); PDB accession (7); 3D entries (4); cryst (0)
Summary
Download GH136 (1200) Taxonomic display Structure (4) Characterized (7)
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Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 SGY26_02015   Lacticaseibacillus paracasei M115-8W-2 WPP12879.1    
 HCJ88_12240   Lacticaseibacillus paracasei NFFJ04 QOP56481.1    
 OK107_00230   Lacticaseibacillus paracasei NG-LCU-NJ2 WBS99157.1    
 G5C68_08515   Lacticaseibacillus paracasei NSMJ15 QOP48321.1    
 NY1301_27480   Lacticaseibacillus paracasei NY1301 BEQ12507.1    
 MRE03_12340   Lacticaseibacillus paracasei SCB0563 UOG14930.1    
 NPC72_13690   Lacticaseibacillus paracasei SMN-LBK UUD40971.1    
 L3C06_13495   Lacticaseibacillus paracasei subsp. paracasei 0562 UJS07585.1    
 LBPG_01250   Lacticaseibacillus paracasei subsp. paracasei 8700:2 EEQ65801.2    
 J5Y16_07545   Lacticaseibacillus paracasei subsp. paracasei GR0548 QXJ69339.1    
 KFU60_08920   Lacticaseibacillus paracasei subsp. tolerans 2A QUT00082.1    
 LacP0245_08900   Lacticaseibacillus paracasei subsp. tolerans MGB0245 QPC12346.1    
 LacP0625_14345   Lacticaseibacillus paracasei subsp. tolerans MGB0625 QPC23463.1    
 LacP0734_11010   Lacticaseibacillus paracasei subsp. tolerans MGB0734 QPC20336.1    
 JK381_13630   Lacticaseibacillus paracasei subsp. tolerans S-NA5 QQX67886.1    
 JK384_13640   Lacticaseibacillus paracasei subsp. tolerans S-NB QQX72438.1    
 I3F57_13940   Lacticaseibacillus paracasei subsp. tolerans ZY-1 QPI87989.1    
 CFM84_11550   Lacticaseibacillus paracasei ZFM54 AYG23690.1    
 LCAZH_2658   Lacticaseibacillus casei str. Zhang ADK19846.1    
 A0F16_11355   Lacticaseibacillus rhamnosus ASCC 290 AMQ04011.1    
 LRHK_2789   Lacticaseibacillus rhamnosus ATCC 8530 AER65507.1    
 JGE02_12685   Lacticaseibacillus rhamnosus B6 QQN33031.1    
 GMB04_13270   Lacticaseibacillus rhamnosus BIO5326 QGQ36117.1    
 NOS86_12315   Lacticaseibacillus rhamnosus CLK 101 UUA00941.1    
 V1641_12705   Lacticaseibacillus rhamnosus CP WVV46788.1    
 NHB23_001150   Lacticaseibacillus rhamnosus DM065 UVF17172.1    
 QZ130_12520   Lacticaseibacillus rhamnosus DM163 WKJ95314.1    
 NUU07_12320   Lacticaseibacillus rhamnosus GR-1 UUY22505.1    
 GEK51_09980   Lacticaseibacillus rhamnosus IDCC 3201 QFV11089.1    
 QJQ50_12240   Lacticaseibacillus rhamnosus k32 WHM91149.1    
 LC705_02680   Lacticaseibacillus rhamnosus Lc 705 CAR91519.1    
 RWA14_12680   Lacticaseibacillus rhamnosus LMG 10768 WNX20779.1    
 RWA22_12180   Lacticaseibacillus rhamnosus LMG 19716 WNX15325.1    
 RWA17_12445   Lacticaseibacillus rhamnosus LMG 19717 WNX11114.1    
 RWA13_12715   Lacticaseibacillus rhamnosus LMG 23277 WNX10110.1    
 RWA21_12740   Lacticaseibacillus rhamnosus LMG 23327 WNX05855.1    
 RWA20_13440   Lacticaseibacillus rhamnosus LMG 23550 WNX18139.1    
 RWA19_12765   Lacticaseibacillus rhamnosus LMG 23551 WNX03179.1    
 LOCK900_2679   Lacticaseibacillus rhamnosus LOCK900 AGP72456.1    
 LOCK908_2760   Lacticaseibacillus rhamnosus LOCK908 AGP75366.1    
 BGK71_12685   Lacticaseibacillus rhamnosus LR5 ASX18217.1    
 HPC59_00135   Lacticaseibacillus rhamnosus LV108 QJZ31175.1    
 NCTC13710_02632   Lacticaseibacillus rhamnosus NCTC13710 VEF30702.1    
 NCTC13764_02625   Lacticaseibacillus rhamnosus NCTC13764 VEF64230.1    
 BVH57_01980   Lacticaseibacillus rhamnosus Pen ARD31274.1    
 LL671_01130   Lacticaseibacillus rhamnosus PMC203 UEM72594.1    
 RI131_13515   Lacticaseibacillus rhamnosus VHProbi M12 WND15831.1    
 MU539_12320   Lacticaseibacillus rhamnosus VHProbi M14 UUT38176.1    
 RI130_12405   Lacticaseibacillus rhamnosus VHProbi V6156 WND26753.1    
 LT346_12700   Lacticaseibacillus rhamnosus VHProbi Y39 UKW36521.1    
 PUW67_12715   Lacticaseibacillus rhamnosus VSI33 WEA92104.1    
 KEM50_12755   Lacticaseibacillus rhamnosus X253 QUO46462.1    
 LACPH_002567   Lacticaseibacillus sp. NCIMB 15471 WLV77788.1    
 LACSTY_002647   Lacticaseibacillus sp. NCIMB 15473 WLV80560.1    
 LACZS1_002570   Lacticaseibacillus sp. NCIMB 15474 WLV86134.1    
 LACZS2_002621   Lacticaseibacillus sp. NCIMB 15475 WLV83385.1    
 KG087_13555   Lacticaseibacillus zeae FBL8 QVI31874.1    
 OZX76_01650   Lactobacillus sp. ESL0677 WEV37314.1    
 OZX76_09480   Lactobacillus sp. ESL0677 WEV36950.1    
 Verru16b_01375   Lacunisphaera limnophila IG16b AOS44314.1    
 O159_17290   Leifsonia xyli subsp. cynodontis DSM 46306 AGW41771.1    
 PQO03_02810   Lentisphaera profundi SAORIC-696 WDE96889.1    
 PQO03_02805   Lentisphaera profundi SAORIC-696 WDE96888.1    
 LJT99_15985   Lentisphaerae bacterium WC36 UDQ97924.1    
 SMSP2_00242   Limihaloglobus sulfuriphilus SM-Chi-D1 AQQ69908.1    
 L2Y96_11720   Luteibacter aegosomaticola 335 UPG88088.1    
 L2Y94_10575   Luteibacter aegosomatis 321 UPG87773.1    
 L2Y97_11975   Luteibacter aegosomatissinici 353 UPG92587.1    
 FIV34_11005   Luteibacter pinisoli MAH-14 QDE39692.1    
 KDY119_03183   Luteimicrobium xylanilyticum HY-24 QFU99648.1    
 VV02_16750 (fragment)   Luteipulveratus mongoliensis MN07-A0370 AKU17124.1    
 VV02_19065 (fragment)   Luteipulveratus mongoliensis MN07-A0370 AKU19103.1    
 KBB96_09140   Luteolibacter ambystomatis 32A QUE53042.1    
 HHL09_06530   Luteolibacter luteus G-1-1-1 QJE95450.1    
 llg_44410   Luteolibacter sp. LG18 BCU79726.1    
 MKD41_08675   Lutibacter sp. A64 UMB52415.1    
 MHL31_14015   Lutibacter sp. A80 UMB60188.1    
 RBH95_13265   Mangrovimonas sp. YM274 WMI68110.1    
 DAT1033_p1005 (fragment)   Melissococcus plutonius DAT1033 BBP08122.1    
 DAT561_p1004   Melissococcus plutonius DAT561 BBC61707.1    
 MPD5_1794   Melissococcus plutonius DAT561 BAL62976.1    
 DAT585_p1005 (fragment)   Melissococcus plutonius DAT585 BBD15941.1    
 DAT606_p1005 (fragment)   Melissococcus plutonius DAT606 BBD17566.1    
 L2X98_09890   Microbacterium elymi KUDC0405 UJP11906.1    
 IC745_11305   Microbacterium hominis 01094 QOC24955.1    
 IC744_00660   Microbacterium hominis 01094 QOC29003.1    
 JVX92_13830   Microbacterium hominis PDNC016 QRY40543.1    
 CXR34_06105   Microbacterium hominis SJTG1 AUG29084.1    
 PQV94_14385   Microbacterium sp. Clip185 WDG17796.1    
 MNR00_15900 (fragment)   Microbacterium sp. H1-D42 UNK70620.1    
 MNR00_00845   Microbacterium sp. H1-D42 UNK71022.1    
 L2X99_09700   Microbacterium sp. KUDC0406 UJP08789.1    
 LMS4_002086   Microbacterium sp. LMS4 WXK54429.1    
 LTA6_001789   Microbacterium sp. LTA6 WXH16371.1    
 KY498_06090   Microbacterium sp. PAMC21962 QYF98788.1    
 CEP17_10540   Microbacterium sp. PM5 AXA96805.1    
 KV396_05185   Microbacterium sp. SSW1-36 UPL13906.1    
 MTES_1613   Microbacterium testaceum StLB037 BAJ74577.1    
 OVN18_07435   Microcella daejeonensis MMS21-STM12 WAB80409.1    
 NNL39_05800   Microcella humidisoli MMS21-STM10 UTT63612.1    
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