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Glycoside Hydrolase Family 136

Activities in FamilyLacto-N-biosidase (Lewis antigen a/b specificity) (EC 3.2.1.-);
Lacto-N-biosidase (EC 3.2.1.140);
Mechanism Retaining e
3D Structure Statusparallel β-helix
Catalytic Nucleophile/BaseAsp
Catalytic Proton DonorAsp
NoteCreated after Yamada et al. (2017) Cell Chem Biol 24:515-524 (PMID=28392148)
External resourcesCAZypedia;
Statistics GenBank accession (1161); Uniprot accession (7); PDB accession (7); 3D entries (4); cryst (0)
Summary
Download GH136 (1200) Taxonomic display Structure (4) Characterized (7)
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Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 N7E81_18805   Reichenbachiella carrageenanivorans Wsw4-B4 UXX79406.1    
 RSal33209_0350   Renibacterium salmoninarum ATCC 33209 ABY22105.1    
 J2J98_05485   Rhizobium bangladeshense BLR175 QSY89589.1    
 J2J97_05575   Rhizobium bangladeshense PLR8-1a QSY95395.1    
 J0663_11860 (fragment)   Rhizobium lentis BLR27 QSW91820.1    
 PO860_11800   Rhizobium sp. BJ04 WEA58404.1    
 AMK05_CH02020   Rhizobium sp. N324 ANM10406.1    
 AMK06_CH01989   Rhizobium sp. N541 ANM16891.1    
 AMK07_CH01986   Rhizobium sp. N941 ANM23276.1    
 lacto-N-biosidase (RhLnb136II; RHOM_04115) (possible fragment) 3.2.1.140 Roseburia hominis A2-183 AEN95945.1 G2T0V1  
 NQ522_09085   Roseburia intestinalis L1 82 UWP57351.1    
 RIL182_01812   Roseburia intestinalis L1-82 VCV21936.1    
 ROI_24270 (fragment)   Roseburia intestinalis M50/1 CBL09394.1    
 M5E85_08525   Roseburia intestinalis NB2A 31_NB UQT32278.1    
 RO1_13270   Roseburia intestinalis XB6B4 CBL11957.1    
 lacto-N-biosidase (Lewis antigen a/b specificity) (RiLea/b136) 3.2.1.- Roseburia inulinivorans WP_007885622.1 C0FT31  
 H8S51_010700   Roseburia rectibacter NSJ-69 UMY98786.1    
 FF011L_34800   Roseimaritima multifibrata FF011L QDS94700.1    
 TH63_14980   Rufibacter radiotolerans DG31D AKQ46634.1    
 DC20_05170   Rufibacter tibetensis 1351 ALJ01227.1    
 lacto-N-biosidase (RlXc;RUMLAC_RS05545) 3.2.1.140 Ruminococcus lactaris WP_005610277.1 B5CMC4  
 NQ541_10615   [Ruminococcus] lactaris ATCC 29176 UWP65170.1    
 Rumi1_15320   [Ruminococcus] torques 17CBH32 BEI75734.1    
 Rumi2_12700   [Ruminococcus] torques 17EGH124 BEI78110.1    
 RUMTOR_00181   [Ruminococcus] torques ATCC 27756 EDK25288.1    
 FFV09_14695   Saccharibacillus brassicae ATSA2 QDH21977.1    
 GCM10017745_34910   Saccharothrix mutabilis subsp. capreolus JCM 4248 BFE50064.1    
 NCTC7300_04232   Salmonella enterica subsp. arizonae NCTC7300 VDY44809.1    
 FORC20_4010   Salmonella enterica subsp. enterica serovar Typhimurium FORC_020 ALP99787.1    
 L21SP3_01049   Sedimentisphaera cyanobacteriorum L21-RPul-D3 AQQ09247.1    
 L21SP3_01759 (CglA)   Sedimentisphaera cyanobacteriorum L21-RPul-D3 AQQ09938.1    
 L21SP3_01758   Sedimentisphaera cyanobacteriorum L21-RPul-D3 AQQ09937.1    
 STSP1_01810   Sedimentisphaera salicampi ST-PulAB-D4 ARN57403.1    
 STSP1_01614   Sedimentisphaera salicampi ST-PulAB-D4 ARN57216.1    
 STSP1_01811 (CglA)   Sedimentisphaera salicampi ST-PulAB-D4 ARN57404.1    
 H9Q77_03535   Simiaoa sunii NSJ-8 QNM03227.1    
 Sinac_4418   Singulisphaera acidiphila DSM 18658 AGA28608.1    
 U8C31_14915   Sinorhizobium medicae ml2 WQO71573.1    
 U8C40_15180   Sinorhizobium medicae ml29 WQO64474.1    
 SmedWSM1115_12265   Sinorhizobium medicae WSM1115 UFX00583.1    
 Sinme_2295   Sinorhizobium meliloti AK83 AEG54014.1    
 CDO26_02530   Sinorhizobium meliloti M270 ASP83608.1    
 U8C39_28880 (fragment)   Sinorhizobium meliloti ml21 WQP05848.1    
 U8C39_28885 (fragment)   Sinorhizobium meliloti ml21 WQP05849.1    
 U8C45_28840   Sinorhizobium meliloti ml45 WQP32643.1    
 U8C43_27695   Sinorhizobium meliloti ml47 WQP26255.1    
 U8C33_29290   Sinorhizobium meliloti ml59 WQP19153.1    
 U8C30_27745   Sinorhizobium meliloti ml66 WQP12773.1    
 HB772_15735   Sinorhizobium meliloti RCAM1115 QND33545.1    
 SM11_chr1102   Sinorhizobium meliloti SM11 AEH78379.1    
 D0B54_23445   Solimonas sp. K1W22B-7 AXQ31456.1    
 HS960_10800   Sphingobacterium multivorum BIGb0170 QMV68119.1    
 I6I97_23355   Sphingobacterium multivorum FDAARGOS_1140 QQT62065.1    
 I6I98_14025   Sphingobacterium multivorum FDAARGOS_1141 QQT51418.1    
 I6I99_08945   Sphingobacterium multivorum FDAARGOS_1142 QQT32662.1    
 I6J00_01005   Sphingobacterium multivorum FDAARGOS_1143 QQT45297.1    
 I6J33_13430   Sphingobacterium multivorum FDAARGOS_1203 QRQ59212.1    
 K2F45_10445   Sphingobacterium siyangense FTD2 UQA77361.1    
 JVX97_21080   Sphingobacterium siyangense PDNC006 QRY56489.1    
 BV902_11755   Sphingobacterium sp. B29 APU96936.1    
 OGI71_15555   Sphingobacterium sp. ML3W WFA77480.1    
 JAZ75_16815   Sphingobacterium sp. UDSM-2020 QQD12260.1    
 OK025_23495   Sphingobacterium sp. UGAL515B_05 WON94197.1    
 SAMIE_1034220   Sphingobium amiense DSM 16289 BBD99921.1    
 QQ987_19925   Sphingobium baderi SC-1 WRD78663.1    
 H5V43_08085   Sphingobium barthaii KK22 QOT70139.1    
 FIL70_10365   Sphingobium fuliginis ATCC 27551 QDC37557.1    
 IZV00_14645   Sphingobium sp. Cam5-1 QPI74949.1    
 GL174_03525   Sphingobium sp. CAP-1 QGP78168.1    
 EP837_03632   Sphingobium sp. EP60837 ANI80016.1    
 NUH86_01030   Sphingobium sp. JS3065 UZW55419.1    
 K663_19021   Sphingobium sp. MI1205 AMK20165.1    
 E5554_21885   Sphingobium sp. PAMC28499 QCB40252.1    
 BSY17_3476   Sphingobium sp. RAC03 AOF95234.1    
 EGM87_08805   Sphingobium sp. RSMS UXC92533.1    
 K426_07410   Sphingobium sp. TKS AMK22429.1    
 K426_26525   Sphingobium sp. TKS AMK26204.1    
 K3M67_16750   Sphingobium sp. V4 WIW90717.1    
 N6H05_08920   Sphingobium sp. WTD-1 WIA57898.1    
 TZ53_21180   Sphingobium sp. YBL2 AJR25881.1    
 PO876_01885   Sphingobium sp. YC-XJ3 WDA36988.1    
 PO876_07850   Sphingobium sp. YC-XJ3 WDA38067.1    
 YGS_C2P1260 (fragment)   Sphingobium sp. YG1 BBD03246.1    
 H3V42_24405   Sphingobium yanoikuyae A3 QNG44937.1    
 PAE53_14895   Sphingobium yanoikuyae CC4533 WBQ15208.1    
 U0025_15875   Sphingobium yanoikuyae HAMBI_1842 WQE05780.1    
 A6768_17375   Sphingobium yanoikuyae S72 ATI81588.1    
 BV87_08070   Sphingobium yanoikuyae SHJ ATP18360.1    
 EBF16_17180   Sphingobium yanoikuyae SJTF8 AYO78464.1    
 GS397_16355   Sphingobium yanoikuyae YC-JY1 QHD68461.1    
 HH800_17250   Sphingobium yanoikuyae YC-XJ2 QJR03779.1    
 GXP74_28355   Streptacidiphilus sp. P02-A3a QMU71568.1    
 GXW83_23185   Streptacidiphilus sp. PB12-B1b QMU78170.1    
 GXW83_24715   Streptacidiphilus sp. PB12-B1b QMU78434.1    
 M0P28_10045   Streptococcus pasteurianus WUSP074 WCQ72137.1    
 RJD36_10085   Streptococcus pasteurianus WUSP082 WOO57457.1    
 PXH68_01145   Streptococcus sp. 29896 WNY47342.1    
 HAS68_0183   Streptococcus suis 05HAS68 AHF58710.1    
 SSU05_0214   Streptococcus suis 05ZYH33 ABP89182.1    
 NLY77_01155   Streptococcus suis 1521251 UTI51072.1    
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