GlycosylTransferase Family 8

Activities in Familylipopolysaccharide α-1,3-galactosyltransferase (EC; UDP-Glc: (glucosyl)lipopolysaccharide α-1,2-glucosyltransferase (EC 2.4.1.-); lipopolysaccharide glucosyltransferase 1 (EC; glycogenin glucosyltransferase (EC; inositol 1-α-galactosyltransferase (galactinol synthase) (EC; homogalacturonan α-1,4-galacturonosyltransferase (EC; UDP-GlcA: xylan α-glucuronyltransferase (EC 2.4.1.-)
Mechanism Retaining
3D Structure StatusGT-A
NoteDistant similarity to family GT24; The animal LARGE bifunctional glycosyltransferases are made of two domains. The N-terminal domain, which adds a-1,3-Xyl residues, belongs to family GT8 while the C-terminal domain, which adds b-1,3-GlcA residues, belongs to family GT49.
External resourcesGlymap; HOMSTRAD;
Commercial Enzyme Provider(s)CHEMILY;
Statistics GenBank accession (10472); Uniprot accession (1210); PDB accession (43); 3D entries (9); cryst (0)
All (8862) Archaea (7) Bacteria (7385) Eukaryota (1318) Viruses (149) unclassified (3) Structure (9) Characterized (52)
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | ... | 74 |
Protein Name EC#OrganismGenBank UniprotPDB/3D
 C1N92_09815   Bacillus velezensis SGAir0473 AWQ15161.1    
 V529_38370 (GspA)   Bacillus velezensis SQR9 AHZ17863.1    
 S100072_03844 (WaaJ)   Bacillus velezensis SRCM100072 ASB55149.1    
 S101413_04244 (WaaJ)   Bacillus velezensis SRCM101413 ASB67660.1    
 BLL65_00865   Bacillus velezensis sx01604 AQZ71604.1    
 CEG11_18290   Bacillus velezensis T20E-257 ASF56937.1    
 CG798_04340   Bacillus velezensis TB1501 ASP24500.1    
 AJ82_20125   Bacillus velezensis TrigoCor1448 AHK51055.1    
 RBAU_3696 (GspA)   Bacillus velezensis UCMB5033 CDG31662.1    
 BAM5036_3487 (GspA)   Bacillus velezensis UCMB5036 CCP23493.1    
 BASU_3474 (GspA)   Bacillus velezensis UCMB5113 CDG27750.1    
 C6P48_00870   Bacillus velezensis VCC-2003 AVM06901.1    
 BANAU_3747 (GspA)   Bacillus velezensis YAU B9601-Y2 CCG51768.1    
 AAV30_01190   Bacillus velezensis YJ11-1-4 AKF74877.1    
 CGC64_04460   Bacteroides caccae ATCC 43185 ASM65285.1    
 ABI39_06210   Bacteroides dorei CL03T12C01 AND19078.1    
 EL88_03920   Bacteroides dorei isolate HS1_L1_B_010 AII62363.1    
 GV66_14555   Bacteroides dorei isolate HS1_L3_B_079 AII68844.1    
 IY41_14970   Bacteroides dorei isolate HS2_L_2_B_045b ALA74625.1    
 BF638R_4286   Bacteroides fragilis 638R CBW24706.1 E1WQT0  
 BF638R_0174   Bacteroides fragilis 638R CBW20782.1 E1WK61  
 MB0529_04140 (Gspa_2)   Bacteroides fragilis BE1 CUA20721.1    
 MB0529_00165 (Gspa_1)   Bacteroides fragilis BE1 CUA16831.1    
 VU15_00465   Bacteroides fragilis BOB25 AKA50335.1    
 VU15_20405   Bacteroides fragilis BOB25 AKA53811.1    
 BF0184   Bacteroides fragilis NCTC 9343 CAH05961.1 Q5LIR5  
 BF1557   Bacteroides fragilis NCTC 9343 CAH07262.1 Q5LF36  
 BF4202   Bacteroides fragilis NCTC 9343 CAH09874.1 Q5L7S5  
 BUN20_20435   Bacteroides fragilis Q1F2 AUI48674.1    
 AE940_09725   Bacteroides fragilis S14 ANQ61059.1    
 AE940_18040   Bacteroides fragilis S14 ANQ62529.1    
 AE940_16355   Bacteroides fragilis S14 ANQ62226.1    
 BF4403   Bacteroides fragilis YCH46 BAD51141.1 Q64MZ6  
 BF0225   Bacteroides fragilis YCH46 BAD46974.1 Q64ZV2  
 C3V43_08370   Bacteroides heparinolyticus F0111 AVM57768.1    
 Btheta7330_02113 (Gspa_2)   Bacteroides thetaiotaomicron 7330 ALJ41670.1    
 Btheta7330_00158 (Gspa_1) (fragment)   Bacteroides thetaiotaomicron 7330 ALJ39758.1    
 BT2873   Bacteroides thetaiotaomicron VPI-5482 AAO77979.1
 BXY_16020 (fragment)   Bacteroides xylanisolvens XB1A CBK66720.1 D6CX18  
 F544_19090   Bibersteinia trehalosi USDA-ARS-USMARC-190 AHG87137.1    
 BADO_1523   Bifidobacterium adolescentis 22L AII76931.1    
 BADO_1516   Bifidobacterium adolescentis 22L AII76924.1    
 CKK50_08405   Bifidobacterium adolescentis 6 AXR42330.1    
 CKK50_08455   Bifidobacterium adolescentis 6 AXR42339.1    
 BBAG_1463   Bifidobacterium angulatum DSM 20098 = JCM 7096 BAQ97085.1    
 Bang102_001510   Bifidobacterium angulatum GT102 AMK58470.1    
 Bang102_001480   Bifidobacterium angulatum GT102 AMK58469.1    
 BBBF_0064   Bifidobacterium bifidum ATCC 29521 = JCM 1255 = DSM 20456 BAQ97271.1    
 BBBF_0053   Bifidobacterium bifidum ATCC 29521 = JCM 1255 = DSM 20456 BAQ97260.1    
 RY70_118   Bifidobacterium bifidum BF3 ALE10506.1    
 RY70_106   Bifidobacterium bifidum BF3 ALE10494.1    
 BBJK_01504   Bifidobacterium bifidum LMG 13195 JCM 7004 BBA48037.1    
 BBJK_01529   Bifidobacterium bifidum LMG 13195 JCM 7004 BBA48052.1    
 BBKW_1747 (fragment)   Bifidobacterium kashiwanohense JCM 15439 = DSM 21854 BAQ29882.1    
 BBKW_1743   Bifidobacterium kashiwanohense JCM 15439 = DSM 21854 BAQ29878.1    
 BL105A_1801   Bifidobacterium longum 105-A BAP84407.1    
 BL105A_1797   Bifidobacterium longum 105-A BAP84403.1    
 B624_1673   Bifidobacterium longum 35624 AOL11116.1    
 B624_1677   Bifidobacterium longum 35624 AOL11120.1    
 GS08_09765   Bifidobacterium longum BXY01 AIF91358.1    
 GS08_09800   Bifidobacterium longum BXY01 AIF91364.1    
 Blon_2388   Bifidobacterium longum subsp. infantis ATCC 15697 = JCM 1222 = DSM 20088 ACJ53443.1 B7GNT7  
 Blon_2385   Bifidobacterium longum subsp. infantis ATCC 15697 = JCM 1222 = DSM 20088 ACJ53440.1 B7GNT4  
 BLIJ_2456   Bifidobacterium longum subsp. infantis ATCC 15697 = JCM 1222 = DSM 20088 BAJ70033.1    
 BLIJ_2459   Bifidobacterium longum subsp. infantis ATCC 15697 = JCM 1222 = DSM 20088 BAJ70036.1    
 DVB78_09120   Bifidobacterium longum subsp. longum BORI AXF99499.1    
 DVB78_09105   Bifidobacterium longum subsp. longum BORI AXF99259.1    
 BLJ_1883   Bifidobacterium longum subsp. longum JDM301 ADH01306.1 D6ZWQ0  
 BLJ_1890   Bifidobacterium longum subsp. longum JDM301 ADH01313.1 D6ZWQ7  
 D805_0387   Bifidobacterium thermophilum RBL67 AGH40654.1    
 ADH70_000695   Blautia coccoides YL58 ASU27511.1    
 A4V09_02375   Blautia sp. YL58 ANU74707.1    
 BHAMNSH16_11865   Brachyspira hampsonii NSH-16 ASJ22296.1    
 BHYOB78_11870   Brachyspira hyodysenteriae ATCC 27164 B-78 ANN64533.1    
 BHYOB78_00840   Brachyspira hyodysenteriae ATCC 27164 B-78 ANN62450.1    
 BHYOB78_05155 (fragment)   Brachyspira hyodysenteriae ATCC 27164 B-78 ANN63267.1    
 BH718_00604   Brachyspira hyodysenteriae BH718 AUJ49061.1    
 BHWA1_00827   Brachyspira hyodysenteriae WA1 ACN83320.1 C0QZN2  
 BHWA1_02200 (RfaJ) (fragment)   Brachyspira hyodysenteriae WA1 ACN84658.1 C0QW72  
 Bint_1015 (fragment)   Brachyspira intermedia PWS/A AEM21638.1    
 Bint_2478 (fragment)   Brachyspira intermedia PWS/A AEM23082.1    
 Bmur_0705   Brachyspira murdochii DSM 12563 ADG70804.1 D5U7Y1  
 Bmur_0700   Brachyspira murdochii DSM 12563 ADG70799.1 D5U7X6  
 Bmur_0702   Brachyspira murdochii DSM 12563 ADG70801.1 D5U7X8  
 Bmur_0704   Brachyspira murdochii DSM 12563 ADG70803.1 D5U7Y0  
 Bmur_2101   Brachyspira murdochii DSM 12563 ADG72176.1 D5U3U4  
 Bmur_2104   Brachyspira murdochii DSM 12563 ADG72179.1 D5U3Z8  
 BP951000_1077 (LgtC)   Brachyspira pilosicoli 95/1000 ADK31067.1 D8ID44  
 B2904_orf268   Brachyspira pilosicoli B2904 AFR69625.1    
 B2904_orf2571   Brachyspira pilosicoli B2904 AFR71893.1    
 B2904_orf826 (fragment)   Brachyspira pilosicoli B2904 AFR70171.1    
 BPP43_09675   Brachyspira pilosicoli P43/6/78 AGA67117.1    
 WESB_2422   Brachyspira pilosicoli WesB CCG57884.1    
 WESB_2570   Brachyspira pilosicoli WesB CCG58032.1    
 AWC36_19620   Brenneria goodwinii FRB141 ATA26145.1    
 AB432_004180   Brevibacillus brevis DZQ7 AWX54284.1    
 BBR47_07340 (GspA)   Brevibacillus brevis NBRC 100599 NBRC 100599 (= 47) BAH41711.1 C0Z4I4  
 A616_04295   Brevibacillus brevis X23 ATF11247.1    
 BP422_29090   Brevibacillus formosus NF2 ASJ57206.1    
 BRPE64_BCDS12460   Burkholderia insecticola RPE64 BAN25907.1    

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