GlycosylTransferase Family 8

Activities in Familylipopolysaccharide α-1,3-galactosyltransferase (EC 2.4.1.44); UDP-Glc: (glucosyl)lipopolysaccharide α-1,2-glucosyltransferase (EC 2.4.1.-); lipopolysaccharide glucosyltransferase 1 (EC 2.4.1.58); glycogenin glucosyltransferase (EC 2.4.1.186); inositol 1-α-galactosyltransferase (galactinol synthase) (EC 2.4.1.123); homogalacturonan α-1,4-galacturonosyltransferase (EC 2.4.1.43); UDP-GlcA: xylan α-glucuronyltransferase (EC 2.4.1.-)
Mechanism Retaining
3D Structure StatusGT-A
NoteDistant similarity to family GT24; The animal LARGE bifunctional glycosyltransferases are made of two domains. The N-terminal domain, which adds a-1,3-Xyl residues, belongs to family GT8 while the C-terminal domain, which adds b-1,3-GlcA residues, belongs to family GT49.
External resourcesGlymap; HOMSTRAD;
Commercial Enzyme Provider(s)CHEMILY;
Statistics GenBank accession (8923); Uniprot accession (1210); PDB accession (43); 3D entries (9); cryst (0)
All (7313) Archaea (7) Bacteria (5892) Eukaryota (1272) Viruses (139) unclassified (3) Structure (9) Characterized (52)
| 1 | ... | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | ... | 59 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 GspA-1   Enterococcus faecalis V583 AAO81578.1
AAR59851.1
NP_815508.1
Q833W5  
 GspA-2   Enterococcus faecalis V583 AAO81579.1
AAR59852.1
NP_815509.1
Q833W4  
 EFW11_1466 (Gspα-1)   Enterococcus faecalis W11 BAV36705.1    
 EFW11_1467 (Gspα-2)   Enterococcus faecalis W11 BAV36706.1    
 pEfm12493_084 (fragment)   Enterococcus faecium AJY53568.1    
 EFE1002_1229   Enterococcus faecium CUX98707.1    
 EFE1002_1230   Enterococcus faecium CUX98708.1    
 Sequence 6686 from patent US 6583275   Enterococcus faecium AAQ46128.1
AQY28456.1
AQY32541.1
CVH53289.1
   
 Sequence 6172 from patent US 6583275   Enterococcus faecium AAQ45614.1
AQY28455.1
AQY32540.1
CVH53290.1
   
 CDL00_03050   Enterococcus faecium 16-346 ATU29410.1    
 CDL00_03055   Enterococcus faecium 16-346 ATU29411.1    
 AMR85_00825   Enterococcus faecium 64/3 ALF48636.1    
 AMR85_00830   Enterococcus faecium 64/3 ALF48637.1    
 AWJ25_06310   Enterococcus faecium 6E6 ALZ51877.1    
 AWJ25_06315   Enterococcus faecium 6E6 ALZ51878.1    
 AX771_06945   Enterococcus faecium ATCC 700221 AMQ97275.1    
 AX771_06950   Enterococcus faecium ATCC 700221 AMQ97276.1    
 EFAU004_01481   Enterococcus faecium Aus0004 AFC63565.1    
 EFAU004_01482   Enterococcus faecium Aus0004 AFC63566.1    
 EFAU085_01516   Enterococcus faecium Aus0085 AGS75470.1    
 EFAU085_01517   Enterococcus faecium Aus0085 AGS75471.1    
 HMPREF0351_11489   Enterococcus faecium DO AFK59113.1    
 HMPREF0351_11490   Enterococcus faecium DO AFK59114.1    
 BO233_06470   Enterococcus faecium E1 APE40124.1    
 BO233_06475   Enterococcus faecium E1 APE40125.1    
 BK413_07205   Enterococcus faecium E232 ATW36234.1    
 BK413_07210   Enterococcus faecium E232 ATW36235.1    
 BK695_07210   Enterococcus faecium E240 ATU00271.1    
 BK695_07205   Enterococcus faecium E240 ATU00270.1    
 BK696_07200   Enterococcus faecium E243 ATU03220.1    
 BK696_07205   Enterococcus faecium E243 ATU03221.1    
 XM37_07130   Enterococcus faecium E39 ANB93915.1    
 XM37_07135   Enterococcus faecium E39 ANB93916.1    
 EfmE745_01664 (Gspa_1)   Enterococcus faecium E745 AOT78966.1    
 EfmE745_01665 (Gspa_2)   Enterococcus faecium E745 AOT78967.1    
 CO994_01456 (Gspa_2)   Enterococcus faecium Efaecium_ER04120.3A AUI18687.1    
 CO994_01455 (Gspa_1)   Enterococcus faecium Efaecium_ER04120.3A AUI18686.1    
 CO995_01455 (Gspa_2)   Enterococcus faecium Efaecium_ER04462.3A AUI21658.1    
 CO995_01454 (Gspa_1)   Enterococcus faecium Efaecium_ER04462.3A AUI21657.1    
 CO996_01455 (Gspa_1)   Enterococcus faecium Efaecium_ER04484.3A AUI24627.1    
 CO996_01456 (Gspa_2)   Enterococcus faecium Efaecium_ER04484.3A AUI24628.1    
 CO997_01461 (Gspa_1)   Enterococcus faecium Efaecium_ER04526.3A AUI33506.1    
 CO997_01462 (Gspa_2)   Enterococcus faecium Efaecium_ER04526.3A AUI33507.1    
 CO998_01454 (Gspa_1)   Enterococcus faecium Efaecium_ER04526.5A AUI27601.1    
 CO998_01455 (Gspa_2)   Enterococcus faecium Efaecium_ER04526.5A AUI27602.1    
 AL014_06590   Enterococcus faecium ISMMS_VRE_1 AOM15943.1    
 AL014_06585   Enterococcus faecium ISMMS_VRE_1 AOM15942.1    
 AL024_03930   Enterococcus faecium ISMMS_VRE_10 AOM36868.1    
 AL024_03925   Enterococcus faecium ISMMS_VRE_10 AOM36867.1    
 AL025_08200   Enterococcus faecium ISMMS_VRE_11 AON60853.1    
 AL025_08205   Enterococcus faecium ISMMS_VRE_11 AON60854.1    
 AL026_01555   Enterococcus faecium ISMMS_VRE_12 APV52878.1    
 AL026_09705   Enterococcus faecium ISMMS_VRE_12 APV54391.1    
 AL026_09700   Enterococcus faecium ISMMS_VRE_12 APV54390.1    
 AL015_08445   Enterococcus faecium ISMMS_VRE_2 AOM19300.1    
 AL015_08440   Enterococcus faecium ISMMS_VRE_2 AOM19299.1    
 AL016_01295   Enterococcus faecium ISMMS_VRE_3 AOM21080.1    
 AL016_01290   Enterococcus faecium ISMMS_VRE_3 AOM21079.1    
 AL016_14420   Enterococcus faecium ISMMS_VRE_3 AOM23580.1    
 AL017_07195   Enterococcus faecium ISMMS_VRE_4 AOM25237.1    
 AL017_07200   Enterococcus faecium ISMMS_VRE_4 AOM25238.1    
 AL018_08035   Enterococcus faecium ISMMS_VRE_5 AOM28382.1    
 AL018_14065   Enterococcus faecium ISMMS_VRE_5 AOM29582.1    
 AL018_08030   Enterococcus faecium ISMMS_VRE_5 AOM28381.1    
 AL020_04305   Enterococcus faecium ISMMS_VRE_7 AOM30655.1    
 AL020_14110   Enterococcus faecium ISMMS_VRE_7 AOM32524.1    
 AL020_04310   Enterococcus faecium ISMMS_VRE_7 AOM30656.1    
 AL021_11555   Enterococcus faecium ISMMS_VRE_8 AOM35000.1    
 AL021_11560   Enterococcus faecium ISMMS_VRE_8 AOM35001.1    
 AL023_07805   Enterococcus faecium ISMMS_VRE_9 APV57180.1    
 AL023_16385   Enterococcus faecium ISMMS_VRE_9 APV58775.1    
 AL023_07800   Enterococcus faecium ISMMS_VRE_9 APV57179.1    
 CNX66_07650   Enterococcus faecium K60-39 ATD78476.1    
 CNX66_07655   Enterococcus faecium K60-39 ATD78477.1    
 CWE29_06480   Enterococcus faecium LS170308 AUC72761.1    
 CWE29_06475   Enterococcus faecium LS170308 AUC72760.1    
 CX663_07590   Enterococcus faecium SC4 AUH47666.1    
 CX663_07595   Enterococcus faecium SC4 AUH47667.1    
 M395_08895   Enterococcus faecium T110 AII39510.1    
 M395_08900   Enterococcus faecium T110 AII39511.1    
 AQ614_06845   Enterococcus faecium UW7606x64/3 TC1 ALL10233.1    
 AQ614_06850   Enterococcus faecium UW7606x64/3 TC1 ALL10234.1    
 UB18_06415   Enterococcus faecium UW8175 AMP61083.1    
 UB18_06410   Enterococcus faecium UW8175 AMP61082.1    
 BOW68_05005   Enterococcus faecium VRE001 APJ06227.1    
 BOW68_05000   Enterococcus faecium VRE001 APJ06226.1    
 BVA20_00796 (Gspa_2)   Enterococcus faecium VREF AQT56269.1    
 BVA20_00795 (Gspa_1)   Enterococcus faecium VREF AQT56268.1    
 AL523_06190   Enterococcus gallinarum FDAARGOS_163 AMG49379.1    
 AL523_03650   Enterococcus gallinarum FDAARGOS_163 AMG48920.1    
 CO692_06595   Enterococcus gallinarum FDAARGOS_375 ATF71767.1    
 ORF   Enterococcus hirae ATCC 9790 ACR18996.1 C4XV75  
 ORF   Enterococcus hirae ATCC 9790 ACR18997.1 C4XV76  
 EHR_11285   Enterococcus hirae ATCC 9790 AFM71136.1    
 EHR_11290   Enterococcus hirae ATCC 9790 AFM71137.1    
 A6J73_08995   Enterococcus hirae FDAARGOS_234 ASV82222.1    
 A6J73_09000   Enterococcus hirae FDAARGOS_234 ASV82223.1    
 A6P53_06710   Enterococcus hirae R17 AND72565.1    
 A6P53_06705   Enterococcus hirae R17 AND72564.1    
 EM4838_06870   Enterococcus mundtii DSM 4838 AUB52717.1    
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