GlycosylTransferase Family 8

Activities in Familylipopolysaccharide α-1,3-galactosyltransferase (EC 2.4.1.44); UDP-Glc: (glucosyl)lipopolysaccharide α-1,2-glucosyltransferase (EC 2.4.1.-); lipopolysaccharide glucosyltransferase 1 (EC 2.4.1.58); glycogenin glucosyltransferase (EC 2.4.1.186); inositol 1-α-galactosyltransferase (galactinol synthase) (EC 2.4.1.123); homogalacturonan α-1,4-galacturonosyltransferase (EC 2.4.1.43); UDP-GlcA: xylan α-glucuronyltransferase (EC 2.4.1.-)
Mechanism Retaining
3D Structure StatusGT-A
NoteDistant similarity to family GT24; The animal LARGE bifunctional glycosyltransferases are made of two domains. The N-terminal domain, which adds a-1,3-Xyl residues, belongs to family GT8 while the C-terminal domain, which adds b-1,3-GlcA residues, belongs to family GT49.
External resourcesGlymap; HOMSTRAD;
Commercial Enzyme Provider(s)CHEMILY;
Statistics GenBank accession (8505); Uniprot accession (1210); PDB accession (41); 3D entries (9); cryst (0)
All (6962) Archaea (7) Bacteria (5588) Eukaryota (1232) Viruses (132) unclassified (3) Structure (9) Characterized (52)
| 1 | ... | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | ... | 56 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 EfmE745_01664 (Gspa_1)   Enterococcus faecium E745 AOT78966.1    
 EfmE745_01665 (Gspa_2)   Enterococcus faecium E745 AOT78967.1    
 AL014_06590   Enterococcus faecium ISMMS_VRE_1 AOM15943.1    
 AL014_06585   Enterococcus faecium ISMMS_VRE_1 AOM15942.1    
 AL024_03930   Enterococcus faecium ISMMS_VRE_10 AOM36868.1    
 AL024_03925   Enterococcus faecium ISMMS_VRE_10 AOM36867.1    
 AL025_08200   Enterococcus faecium ISMMS_VRE_11 AON60853.1    
 AL025_08205   Enterococcus faecium ISMMS_VRE_11 AON60854.1    
 AL026_01555   Enterococcus faecium ISMMS_VRE_12 APV52878.1    
 AL026_09705   Enterococcus faecium ISMMS_VRE_12 APV54391.1    
 AL026_09700   Enterococcus faecium ISMMS_VRE_12 APV54390.1    
 AL015_08445   Enterococcus faecium ISMMS_VRE_2 AOM19300.1    
 AL015_08440   Enterococcus faecium ISMMS_VRE_2 AOM19299.1    
 AL016_01295   Enterococcus faecium ISMMS_VRE_3 AOM21080.1    
 AL016_01290   Enterococcus faecium ISMMS_VRE_3 AOM21079.1    
 AL016_14420   Enterococcus faecium ISMMS_VRE_3 AOM23580.1    
 AL017_07195   Enterococcus faecium ISMMS_VRE_4 AOM25237.1    
 AL017_07200   Enterococcus faecium ISMMS_VRE_4 AOM25238.1    
 AL018_08035   Enterococcus faecium ISMMS_VRE_5 AOM28382.1    
 AL018_14065   Enterococcus faecium ISMMS_VRE_5 AOM29582.1    
 AL018_08030   Enterococcus faecium ISMMS_VRE_5 AOM28381.1    
 AL020_04305   Enterococcus faecium ISMMS_VRE_7 AOM30655.1    
 AL020_14110   Enterococcus faecium ISMMS_VRE_7 AOM32524.1    
 AL020_04310   Enterococcus faecium ISMMS_VRE_7 AOM30656.1    
 AL021_11555   Enterococcus faecium ISMMS_VRE_8 AOM35000.1    
 AL021_11560   Enterococcus faecium ISMMS_VRE_8 AOM35001.1    
 AL023_07805   Enterococcus faecium ISMMS_VRE_9 APV57180.1    
 AL023_16385   Enterococcus faecium ISMMS_VRE_9 APV58775.1    
 AL023_07800   Enterococcus faecium ISMMS_VRE_9 APV57179.1    
 CNX66_07650   Enterococcus faecium K60-39 ATD78476.1    
 CNX66_07655   Enterococcus faecium K60-39 ATD78477.1    
 M395_08895   Enterococcus faecium T110 AII39510.1    
 M395_08900   Enterococcus faecium T110 AII39511.1    
 AQ614_06845   Enterococcus faecium UW7606x64/3 TC1 ALL10233.1    
 AQ614_06850   Enterococcus faecium UW7606x64/3 TC1 ALL10234.1    
 UB18_06415   Enterococcus faecium UW8175 AMP61083.1    
 UB18_06410   Enterococcus faecium UW8175 AMP61082.1    
 BOW68_05005   Enterococcus faecium VRE001 APJ06227.1    
 BOW68_05000   Enterococcus faecium VRE001 APJ06226.1    
 BVA20_00796 (Gspa_2)   Enterococcus faecium VREF AQT56269.1    
 BVA20_00795 (Gspa_1)   Enterococcus faecium VREF AQT56268.1    
 AL523_06190   Enterococcus gallinarum FDAARGOS_163 AMG49379.1    
 AL523_03650   Enterococcus gallinarum FDAARGOS_163 AMG48920.1    
 CO692_06595   Enterococcus gallinarum FDAARGOS_375 ATF71767.1    
 ORF   Enterococcus hirae ATCC 9790 ACR18996.1 C4XV75  
 ORF   Enterococcus hirae ATCC 9790 ACR18997.1 C4XV76  
 EHR_11285   Enterococcus hirae ATCC 9790 AFM71136.1    
 EHR_11290   Enterococcus hirae ATCC 9790 AFM71137.1    
 A6J73_08995   Enterococcus hirae FDAARGOS_234 ASV82222.1    
 A6J73_09000   Enterococcus hirae FDAARGOS_234 ASV82223.1    
 A6P53_06710   Enterococcus hirae R17 AND72565.1    
 A6P53_06705   Enterococcus hirae R17 AND72564.1    
 EMQU_1499   Enterococcus mundtii QU 25 QU25 BAO07056.1    
 EMQU_1498   Enterococcus mundtii QU 25 QU25 BAO07055.1    
 EAM_2155 (WbbM)   Erwinia amylovora ATCC 49946 CBJ46829.1 D4IGD3  
 EAM_2103   Erwinia amylovora ATCC 49946 CBJ46778.1 D4IG82  
 EAIL5_2229   Erwinia amylovora ATCC BAA-2158 CBX81049.1 E5B6M9  
 EAIL5_2290 (fragment)   Erwinia amylovora ATCC BAA-2158 CBX81110.1 E5B5L4  
 EAIL5_2291 (fragment)   Erwinia amylovora ATCC BAA-2158 CBX81111.1 E5B5L5  
 EAMY_2234 (EpsF)   Erwinia amylovora CFBP1430 CBA21321.1 D4HW85  
 EAMY_2176   Erwinia amylovora CFBP1430 CBA21205.1 D4HW27  
 EbC_pEb10200120   Erwinia billingiae Eb661 CAX53290.1 D8MJA2  
 EbC_07750   Erwinia billingiae Eb661 CAX58306.1 D8MN99  
 EbC_27260   Erwinia billingiae Eb661 CAX60257.1 D8MTV0  
 EM595_2321   Erwinia gerundensis EM595 CUU24554.1    
 EPYR_01498   Erwinia pyrifoliae DSM 12163 CAY73878.1 D2T8X1  
 EPYR_01580   Erwinia pyrifoliae DSM 12163 CAY73960.1 D2T953  
 EpC_14040 (WbbM)   Erwinia pyrifoliae Ep1/96 CAX55183.1    
 EpC_14690   Erwinia pyrifoliae Ep1/96 CAX55248.1    
 EJP617_32920   Erwinia sp. Ejp617 ADP12973.1 E3DJ36  
 EJP617_32360   Erwinia sp. Ejp617 ADP12917.1 E3DIH4  
 ETA_13400   Erwinia tasmaniensis Et1/99 CAO96386.1    
 ETA_13870   Erwinia tasmaniensis Et1/99 CAO96433.1    
 EACBF_3507   Escherichia albertii CB9786 BAT41373.1    
 EACBF_3504 (RfaJ)   Escherichia albertii CB9786 BAT41370.1    
 EACBF_3505 (RfaI)   Escherichia albertii CB9786 BAT41371.1    
 EAE6F_3470 (RfaJ)   Escherichia albertii EC06-170 BAT45619.1    
 EAE6F_3471 (RfaI)   Escherichia albertii EC06-170 BAT45620.1    
 EAKF1_ch2315   Escherichia albertii KF1 AHE60187.1    
 EAKF1_ch2316   Escherichia albertii KF1 AHE60188.1    
 EAB3F_3328 (RfaI)   Escherichia albertii NIAH_Bird_3 BAT37069.1    
 EAB3F_3327 (RfaJ)   Escherichia albertii NIAH_Bird_3 BAT37068.1    
 EAB3F_3330   Escherichia albertii NIAH_Bird_3 BAT37071.1    
 A8V37_18520   Escherichia coli Co6114 ANM84392.1    
 A8V37_18530   Escherichia coli Co6114 ANM84394.1    
 A8V37_18535   Escherichia coli Co6114 ANM84395.1    
 NCTC86EC_04168 (Rfai_1)   Escherichia coli SCA73516.1    
 NCTC86EC_04170 (Rfai_2) (fragment)   Escherichia coli SCA73518.1    
 NCTC86EC_04167 (WaaJ)   Escherichia coli SCA73515.1    
 ECWI1_79   Escherichia coli SMB21389.1    
 ECWI2_80   Escherichia coli SMB21606.1    
 ECWI1_80   Escherichia coli SMB21390.1    
 ECWI1_82   Escherichia coli SMB21393.1    
 ECWI2_79   Escherichia coli SMB21604.1    
 ECWI2_82   Escherichia coli SMB21611.1    
 BUQ71_08030   Escherichia coli ARV34560.1    
 BUQ71_08040   Escherichia coli ARV34562.1    
 EC042_3936 (RfaI)   Escherichia coli 042 CBG36759.1 D3H279  
 EC042_3934 (RfaJ)   Escherichia coli 042 CBG36757.1 D3H1R0  
 GJ11_23210   Escherichia coli 06-00048 ANO91576.1    
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