GlycosylTransferase Family 8

Activities in Familylipopolysaccharide α-1,3-galactosyltransferase (EC; UDP-Glc: (glucosyl)lipopolysaccharide α-1,2-glucosyltransferase (EC 2.4.1.-); lipopolysaccharide glucosyltransferase 1 (EC; glycogenin glucosyltransferase (EC; inositol 1-α-galactosyltransferase (galactinol synthase) (EC; homogalacturonan α-1,4-galacturonosyltransferase (EC; UDP-GlcA: xylan α-glucuronyltransferase (EC 2.4.1.-); UDP-Gal:glucoside α-1,3-galactosyltransferase (EC 2.4.1.-)
Mechanism Retaining
3D Structure StatusGT-A
NoteDistant similarity to family GT24; The animal LARGE bifunctional glycosyltransferases are made of two domains. The N-terminal domain, which adds a-1,3-Xyl residues, belongs to family GT8 while the C-terminal domain, which adds b-1,3-GlcA residues, belongs to family GT49.
External resourcesGlymap; HOMSTRAD;
Commercial Enzyme Provider(s)CHEMILY;
Statistics GenBank accession (14211); Uniprot accession (1209); PDB accession (45); 3D entries (10); cryst (0)
All (12615) Archaea (9) Bacteria (10697) Eukaryota (1722) Viruses (184) unclassified (3) Structure (10) Characterized (53)
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | ... | 107 |
Protein Name EC#OrganismGenBank UniprotPDB/3D
 A0U92_16405   Acetobacter aceti TMW2.1153 AQS86068.1    
 AGA_132 (WbbM)   Acetobacter ghanensis LMG 23848T CEF53287.1    
 A0U91_12395   Acetobacter persici TMW2.1084 AQT05521.1    
 FAI41_03385   Acetobacteraceae bacterium 880 QCE32698.1    
 FAI41_03450   Acetobacteraceae bacterium 880 QCE32711.1    
 NCTC10172_00113 (GspA)   Acholeplasma hippikon NCTC10172 VEU82107.1    
 BN85409180   Acholeplasma palmae J233 CCV64495.1    
 Acfer_0493   Acidaminococcus fermentans DSM 20731 ADB46896.1 D2RIJ4  
 Acfer_0496   Acidaminococcus fermentans DSM 20731 ADB46899.1 D2RIJ7  
 Acin_0066   Acidaminococcus intestini RyC-MR95 AEQ21319.1    
 Acin_0070 (WaaI)   Acidaminococcus intestini RyC-MR95 AEQ21323.1    
 BI364_11620   Acidihalobacter prosperus F5 AOU98515.1    
 DLI69_20145   Acinetobacter baumannii 5457 QFV05378.1    
 E5D09_12750   Acinetobacter baumannii ACN21 QBY90241.1    
 GtrOC16   Acinetobacter baumannii D13 AHK10230.1    
 FR761_16220   Acinetobacter baumannii E47 QFH46729.1    
 EGX84_00585   Acinetobacter baumannii FDAARGOS_540 AYX85317.1    
 GtrOC19   Acinetobacter baumannii G21 AUG44334.1    
 B7L46_06075   Acinetobacter baumannii HWBA8 ARG34523.1    
 IOMTU433_0573   Acinetobacter baumannii IOMTU 433 BAP65374.1    
 FED54_02250   Acinetobacter baumannii P7774 QCR87613.1    
 G424_03625   Acinetobacter baumannii PR07 ANS20444.1    
 FDF20_15650   Acinetobacter baumannii VB16141 QCP32317.1    
 AYR69_15585   Acinetobacter baumannii XH857 AML72054.1    
 BFG52_03260   Acinetobacter larvae BRTC-1 AOA57465.1    
 AYJ52_01935   Acinetobacter pittii AP_882 AMM27273.1    
 URS_0301   Acinetobacter ursingii M3 BBF76349.1    
 NCTC12871_00951 (GspA) (fragment)   Actinobacillus delphinicola NCTC12871 VEJ09489.1    
 NCTC8529_01152 (Gspa_2)   Actinobacillus equuli NCTC8529 VEE91091.1    
 NCTC8529_00259 (RfaJ)   Actinobacillus equuli NCTC8529 VEE89389.1    
 NCTC8529_02253 (Gspa_4)   Actinobacillus equuli NCTC8529 VEE93104.1    
 NCTC8529_01265 (Gspa_3)   Actinobacillus equuli NCTC8529 VEE91301.1    
 NCTC8529_00955 (Gspa_1)   Actinobacillus equuli NCTC8529 VEE90729.1    
 NCTC9435_03646 (GspA) (fragment)   Actinobacillus equuli NCTC9435 VEI47729.1    
 NCTC9435_01454 (fragment)   Actinobacillus equuli NCTC9435 VEI45569.1    
 NCTC9435_02044 (RfaJ)   Actinobacillus equuli NCTC9435 VEI46151.1    
 NCTC9435_04051 (fragment)   Actinobacillus equuli NCTC9435 VEI48114.1    
 NCTC9435_04050 (fragment)   Actinobacillus equuli NCTC9435 VEI48113.1    
 ACEE_03620   Actinobacillus equuli subsp. equuli 19392 AIZ78876.1    
 ACEE_05100   Actinobacillus equuli subsp. equuli 19392 AIZ79158.1    
 ACEE_08605   Actinobacillus equuli subsp. equuli 19392 AIZ79827.1    
 ACEE_09595   Actinobacillus equuli subsp. equuli 19392 AIZ80004.1    
 ACEE_10170   Actinobacillus equuli subsp. equuli 19392 AIZ80113.1    
 EXH44_06555   Actinobacillus indolicus AIFJ1607 QBQ63916.1    
 DDU33_09405   Actinobacillus porcitonsillarum 9953L55 AWI51683.1    
 DDU33_01255   Actinobacillus porcitonsillarum 9953L55 AWI50211.1    
 ASU1_09420   Actinobacillus suis ATCC 33415 AIJ32141.1    
 ASU1_04860   Actinobacillus suis ATCC 33415 AIJ31236.1    
 ASU1_08205   Actinobacillus suis ATCC 33415 AIJ31900.1    
 ASU2_04795   Actinobacillus suis H91-0380 AFU19097.1    
 ASU2_08135   Actinobacillus suis H91-0380 AFU19761.1    
 ASU2_09360   Actinobacillus suis H91-0380 AFU20002.1    
 SAMEA4504061_01975 (Gspa_2)   Actinobacillus suis NCTC12996 SNV39072.1    
 SAMEA4504061_01019 (RfaJ)   Actinobacillus suis NCTC12996 SNV31020.1    
 SAMEA4504061_01712 (Gspa_1)   Actinobacillus suis NCTC12996 SNV37034.1    
 AP3564_08250   Aeribacillus pallidus KCTC3564 ASS90217.1    
 AWM72_01190   Aerococcus sanguinicola CCUG43001 AMB93453.1    
 HMPREF9243_0771 (GtfB)   Aerococcus urinae ACS-120-V-Col10a AEA00388.1    
 HMPREF9243_0648   Aerococcus urinae ACS-120-V-Col10a AEA00793.1    
 AWM73_06340   Aerococcus urinae CCUG36881 AMB96149.1    
 AWM73_05825   Aerococcus urinae CCUG36881 AMB96054.1    
 AWM74_06090   Aerococcus urinaeequi CCUG28094 AMB97831.1    
 APT62_08015   Aerococcus urinaeequi USDA-ARS-USMARC-56713 ALZ88390.1    
 AWM76_02285   Aerococcus viridans CCUG4311 AMC00484.1    
 FOB80_02985   Aerococcus viridans FDAARGOS_672 QGS36519.1    
 CK627_03105   Aeromonas dhakensis KN-Mc-6U21 ASX09842.1    
 AHA_4170   Aeromonas hydrophila subsp. hydrophila ATCC 7966 ABK36197.1 A0KQP2  
 BFW41_00765   Aeromonas hydrophila ZYAH75 AXV32536.1    
 C5P03_00775   Aeromonas salmonicida subsp. salmonicida 01-B526 AYO61524.1    
 ASA_0158   Aeromonas salmonicida subsp. salmonicida A449 ABO88356.1 A4SHI4  
 E3D14_21365   Aeromonas salmonicida subsp. salmonicida SHY16-3432 QEO85699.1    
 FE240_12850   Aeromonas simiae A6 QFI55496.1    
 ADJ80_04030   Aggregatibacter aphrophilus W1043 AKU62976.1    
 Arad_3687 (SqdD)   Agrobacterium radiobacter K84 ACM27584.1 B9J9I2  
 PYTT_1533   Akkermansia glycaniphila SEH89708.1    
 PYTT_1537   Akkermansia glycaniphila SEH89766.1    
 PYTT_0794   Akkermansia glycaniphila SEH79418.1    
 PYTT_1657   Akkermansia glycaniphila SEH91256.1    
 EYB66_03820   Akkermansia muciniphila 139 QBH16455.1    
 EYB66_02875   Akkermansia muciniphila 139 QBH16283.1    
 EYB66_02260   Akkermansia muciniphila 139 QBH16169.1    
 CUB89_02895 (fragment)   Akkermansia muciniphila AMDK-1 AYR27611.1    
 CUB89_01410   Akkermansia muciniphila AMDK-1 AYR27348.1    
 CUB89_02580   Akkermansia muciniphila AMDK-1 AYR27552.1    
 CUC06_03555   Akkermansia muciniphila AMDK-2 AYR34542.1    
 CUC06_04180   Akkermansia muciniphila AMDK-2 AYR34654.1    
 CUC06_05205   Akkermansia muciniphila AMDK-2 AYR34833.1    
 CUB96_00565   Akkermansia muciniphila AMDK-3 AYR29513.1    
 CUB96_10860 (fragment)   Akkermansia muciniphila AMDK-3 AYR31268.1    
 CUB96_10865 (fragment)   Akkermansia muciniphila AMDK-3 AYR31269.1    
 CUB96_11875   Akkermansia muciniphila AMDK-3 AYR31437.1    
 CUC01_03145   Akkermansia muciniphila AMDK-4 AYR32189.1    
 CUC01_03770   Akkermansia muciniphila AMDK-4 AYR32297.1    
 CUC01_02170   Akkermansia muciniphila AMDK-4 AYR32024.1    
 Amuc_0634   Akkermansia muciniphila ATCC BAA-835 ACD04471.1 B2UPJ4  
 Amuc_0753   Akkermansia muciniphila ATCC BAA-835 ACD04589.1 B2UQ54  
 Amuc_0939   Akkermansia muciniphila ATCC BAA-835 ACD04771.1 B2UQN6  
 AKKM5201_04395   Akkermansia muciniphila CBA5201 QAT91239.1    
 AKKM5201_06085   Akkermansia muciniphila CBA5201 QAT91535.1    
 AKKM5201_04400   Akkermansia muciniphila CBA5201 QAT91240.1    

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