GlycosylTransferase Family 8

Activities in Familylipopolysaccharide α-1,3-galactosyltransferase (EC 2.4.1.44); UDP-Glc: (glucosyl)lipopolysaccharide α-1,2-glucosyltransferase (EC 2.4.1.-); lipopolysaccharide glucosyltransferase 1 (EC 2.4.1.58); glycogenin glucosyltransferase (EC 2.4.1.186); inositol 1-α-galactosyltransferase (galactinol synthase) (EC 2.4.1.123); homogalacturonan α-1,4-galacturonosyltransferase (EC 2.4.1.43); UDP-GlcA: xylan α-glucuronyltransferase (EC 2.4.1.-)
Mechanism Retaining
3D Structure StatusGT-A
NoteDistant similarity to family GT24; The animal LARGE bifunctional glycosyltransferases are made of two domains. The N-terminal domain, which adds a-1,3-Xyl residues, belongs to family GT8 while the C-terminal domain, which adds b-1,3-GlcA residues, belongs to family GT49.
External resourcesGlymap; HOMSTRAD;
Commercial Enzyme Provider(s)CHEMILY;
Statistics GenBank accession (8505); Uniprot accession (1210); PDB accession (41); 3D entries (9); cryst (0)
All (6962) Archaea (7) Bacteria (5588) Eukaryota (1232) Viruses (132) unclassified (3) Structure (9) Characterized (52)
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Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 CFA70_16940   Citrobacter freundii 18-1 ASK01679.1    
 CES93_00615   Citrobacter freundii 705SK3 ASG42239.1    
 CES93_00610   Citrobacter freundii 705SK3 ASG42238.1    
 CfB38_0110   Citrobacter freundii B38 ANZ85039.1    
 CfB38_0109   Citrobacter freundii B38 ANZ85038.1    
 BTW28_10680   Citrobacter freundii BD APR31391.1    
 BTW28_10685   Citrobacter freundii BD APR31392.1    
 AB180_17595   Citrobacter freundii CAV1321 AKL18748.1    
 AB180_17590   Citrobacter freundii CAV1321 AKL18747.1    
 AB180_17585   Citrobacter freundii CAV1321 AKL18746.1    
 AB183_16340   Citrobacter freundii CAV1741 AKL57410.1    
 AB183_16330   Citrobacter freundii CAV1741 AKL57408.1    
 AB183_16335   Citrobacter freundii CAV1741 AKL57409.1    
 CFNIH1_05750   Citrobacter freundii CFNIH1 AHY11035.1    
 CFNIH1_05745   Citrobacter freundii CFNIH1 AHY11034.1    
 CFNIH1_05740   Citrobacter freundii CFNIH1 AHY11033.1    
 BFQ28_05445   Citrobacter freundii SL151 AOI29288.1    
 BFQ28_05440   Citrobacter freundii SL151 AOI29287.1    
 BN1086_04701 (Rfaj_2)   Citrobacter koseri CDZ86453.1    
 BN1086_04700 (Rfaj_1)   Citrobacter koseri CDZ86452.1    
 BN1086_04702 (Rfaj_3)   Citrobacter koseri CDZ86454.1    
 CKO_05084   Citrobacter koseri ATCC BAA-895 ABV16127.1 A8ARL4  
 CKO_05085   Citrobacter koseri ATCC BAA-895 ABV16128.1 A8ARL5  
 CKO_05086   Citrobacter koseri ATCC BAA-895 ABV16129.1 A8ARL6  
 CEP66_08065   Citrobacter koseri FDAARGOS_287 ASE82591.1    
 CEP66_08070   Citrobacter koseri FDAARGOS_287 ASE82592.1    
 CEP66_08075   Citrobacter koseri FDAARGOS_287 ASE82593.1    
 CO700_22160   Citrobacter koseri FDAARGOS_393 ATF99546.1    
 CO700_22165   Citrobacter koseri FDAARGOS_393 ATF99547.1    
 CO700_22170   Citrobacter koseri FDAARGOS_393 ATF99548.1    
 ROD_41911 (RfaJ)   Citrobacter rodentium ICC168 CBG90889.1 D2TIX7  
 ROD_41901 (RfaI)   Citrobacter rodentium ICC168 CBG90888.1 D2TIX6  
 CITRO86_0483 (WaaI)   Citrobacter sp. 86 SAY83867.1    
 CITRO86_0482 (WaaJ)   Citrobacter sp. 86 SAY83829.1    
 CITRO92_1160 (WaaJ)   Citrobacter sp. 92 SAZ16380.1    
 CITRO92_1161 (WaaI)   Citrobacter sp. 92 SAZ16413.1    
 AL515_00680   Citrobacter sp. FDAARGOS_156 AMH12465.1    
 BED41_12330   Cloacibacillus porcorum CL-84 ANZ45800.1    
 RSJ17_16500   Clostridium argentinense 89G ARC85976.1    
 X276_21255   Clostridium beijerinckii NRRL B-598 ALB48766.1    
 CGC65_03520   [Clostridium] bolteae ATCC BAA-613 ASN93815.1    
 Clocl_3521   [Clostridium] clariflavum DSM 19732 AEV70000.1    
 CKL_1005   Clostridium kluyveri DSM 555 EDK33047.1    
 BS101_06390   Clostridium kluyveri JZZ APM38388.1    
 CKR_0909   Clostridium kluyveri NBRC 12016 BAH05960.1 B9E0D5  
 Closa_3831   [Clostridium] saccharolyticum WM1 ADL06351.1 D9R0B8  
 Cspa_c45570   Clostridium saccharoperbutylacetonicum N1-4(HMT) AGF58310.1    
 SAMN02745906_3436   [Clostridium] sphenoides JCM 1415 ATCC 19403 SET96060.1    
 SAMN02745906_4095   [Clostridium] sphenoides JCM 1415 ATCC 19403 SEU02522.1    
 SAMN02745906_3482   [Clostridium] sphenoides JCM 1415 ATCC 19403 SET96577.1    
 BFX80_05320   Cobetia marina JCM 21022 AOM00818.1    
 LT85_1187   Collimonas arenae Cal35 AIY40345.1    
 LT85_0919   Collimonas arenae Cal35 AIY40077.1    
 CAter10_1095   Collimonas arenae Ter10 AMO98916.1    
 CAter10_0880 (fragment)   Collimonas arenae Ter10 AMO98719.1    
 CAter282_0809   Collimonas arenae Ter282 AMP08612.1    
 CAter282_1012   Collimonas arenae Ter282 AMP08807.1    
 CFU_1045 (WaaI)   Collimonas fungivorans Ter331 AEK60877.1    
 CFter6_1338   Collimonas fungivorans Ter6 AMO94049.1    
 CPter291_1050   Collimonas pratensis Ter291 AMP13327.1    
 CPter291_1054   Collimonas pratensis Ter291 AMP13331.1    
 CPter291_1052   Collimonas pratensis Ter291 AMP13329.1    
 CPter91_1143   Collimonas pratensis Ter91 AMP03527.1    
 CPter91_1147   Collimonas pratensis Ter91 AMP03531.1    
 CPter91_1145   Collimonas pratensis Ter91 AMP03529.1    
 TQ29_08385   Confluentimicrobium sp. EMB200-NS6 ALG90202.1    
 Caka_2544   Coraliomargarita akajimensis DSM 45221 ADE55560.1 D5EP50  
 BJN34_04555   Cupriavidus necator NH9 AQV93167.1    
 Cyagr_1196   Cyanobium gracile PCC 6307 AFY28374.1    
 CBM981_2891   Cyanobium sp. NIES-981 SBO44590.1    
 PCC7424_5779   Cyanothece sp. PCC 7424 ACK73842.1 B7KM20  
 PCC8801_2193   Cyanothece sp. PCC 8801 ACK66221.1 B7K074  
 Cyan8802_2255   Cyanothece sp. PCC 8802 ACV01134.1 C7QL87  
 CA2015_3240   Cyclobacterium amurskyense KCTC 12363 AKP52634.1    
 AKL17_0269   Defluviimonas alba cai42 AMY67531.1    
 AKL17_2308   Defluviimonas alba cai42 AMY69554.1    
 Desde_1226 (fragment)   Desulfitobacterium dehalogenans ATCC 51507 AFL99655.1    
 DPCES_4407 (fragment)   Desulfitobacterium hafniense CDX04293.1    
 Dhaf_1294 (fragment)   Desulfitobacterium hafniense DCB-2 ACL19350.1 B8G232  
 DSY4073   Desulfitobacterium hafniense Y51 BAE85862.1 Q24Q30  
 Desor_5192   Desulfosporosinus orientis DSM 765 AET70577.1    
 AXF13_14550   Desulfovibrio fairfieldensis CCUG 45958 AMD91247.1    
 AXF13_02515   Desulfovibrio fairfieldensis CCUG 45958 AMD89072.1    
 Dvul_2389   Desulfovibrio vulgaris DP4 ABM29405.1 A1VG39  
 XM25_19610   Devosia sp. H5989 AKR57952.1    
 XM25_13300   Devosia sp. H5989 AKR56752.1    
 XM25_19605   Devosia sp. H5989 AKR57951.1    
 DNO_0559   Dichelobacter nodosus VCS1703A ABQ13437.1 A5EVI8  
 Dshi_3427   Dinoroseobacter shibae DFL 12 = DSM 16493 ABV95160.1 A8LP95  
 FH5T_21470   Draconibacterium orientale FH5 AHW61317.1    
 EGYY_20590 (RfaJ)   Eggerthella sp. YY7918 BAK45149.1    
 BBD28_11265   Elizabethkingia anophelis 0422 AQW91197.1    
 BBD31_03895   Elizabethkingia anophelis 3375 AQW97089.1    
 EAAG1_008140   Elizabethkingia anophelis Ag1 ATC39826.1    
 EAAG1_008150   Elizabethkingia anophelis Ag1 ATC39828.1    
 CMV40_08140   Elizabethkingia anophelis AR4-6 ATC47181.1    
 CMV40_08150   Elizabethkingia anophelis AR4-6 ATC47183.1    
 CMV41_08150   Elizabethkingia anophelis AR6-8 ATC43507.1    
 CMV41_08140   Elizabethkingia anophelis AR6-8 ATC43505.1    
 A2T72_09915   Elizabethkingia anophelis CSID_3000521207 AMX51747.1    
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