GlycosylTransferase Family 8

Activities in Familylipopolysaccharide α-1,3-galactosyltransferase (EC; UDP-Glc: (glucosyl)lipopolysaccharide α-1,2-glucosyltransferase (EC 2.4.1.-); lipopolysaccharide glucosyltransferase 1 (EC; glycogenin glucosyltransferase (EC; inositol 1-α-galactosyltransferase (galactinol synthase) (EC; homogalacturonan α-1,4-galacturonosyltransferase (EC; UDP-GlcA: xylan α-glucuronyltransferase (EC 2.4.1.-)
Mechanism Retaining
3D Structure StatusGT-A
NoteDistant similarity to family GT24; The animal LARGE bifunctional glycosyltransferases are made of two domains. The N-terminal domain, which adds a-1,3-Xyl residues, belongs to family GT8 while the C-terminal domain, which adds b-1,3-GlcA residues, belongs to family GT49.
External resourcesGlymap; HOMSTRAD;
Commercial Enzyme Provider(s)CHEMILY;
Statistics GenBank accession (9283); Uniprot accession (1210); PDB accession (43); 3D entries (9); cryst (0)
All (7675) Archaea (7) Bacteria (6249) Eukaryota (1275) Viruses (141) unclassified (3) Structure (9) Characterized (52)
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | ... | 63 |
Protein Name EC#OrganismGenBank UniprotPDB/3D
 AN935_19440   Bacillus subtilis subsp. inaquosorum DE111 AMA54348.1    
 BSNT_05877 (GspA)   Bacillus subtilis subsp. natto BEST195 BAI87514.1
 AWV81_20480   Bacillus subtilis subsp. natto CGMCC 2108 AMK74340.1    
 SD85_19305   Bacillus subtilis subsp. spizizenii NRS 231 AJD38270.1    
 BSUW23_19040 (GspA)   Bacillus subtilis subsp. spizizenii str. W23 ADM39842.1 E0TWQ6  
 GYO_4240   Bacillus subtilis subsp. spizizenii TU-B-10 AEP88800.1    
 BFI33_20745   Bacillus subtilis subsp. subtilis 168G AOA13165.1    
 RP72_20640   Bacillus subtilis subsp. subtilis 3NA AJE96535.1    
 BSU6051_38430 (GspA)   Bacillus subtilis subsp. subtilis 6051-HGW AGG63257.1    
 AT706_19960   Bacillus subtilis subsp. subtilis BSD-2 ALS84053.1    
 AWM80_19630   Bacillus subtilis subsp. subtilis CU1050 AMB26087.1    
 A8O17_18880   Bacillus subtilis subsp. subtilis delta6 ANJ32605.1    
 BEN36_14365   Bacillus subtilis subsp. subtilis IIG-Bs27-47-24 ANY33663.1    
 AS891_03470   Bacillus subtilis subsp. subtilis KCTC 3135 ANX06286.1    
 BEP06_13825   Bacillus subtilis subsp. subtilis PG10 ANY36461.1    
 BEP07_13590   Bacillus subtilis subsp. subtilis PS38 ANY39166.1    
 BHY07_20755   Bacillus subtilis subsp. subtilis QB5412 AOT50134.1    
 BH660_15185   Bacillus subtilis subsp. subtilis QB5413 AOT53171.1    
 S100333_04126 (WaaJ)   Bacillus subtilis subsp. subtilis SRCM100333 ASB71989.1    
 S100757_03909 (WaaJ)   Bacillus subtilis subsp. subtilis SRCM100757 ARW04811.1    
 S100761_03922 (WaaJ)   Bacillus subtilis subsp. subtilis SRCM100761 ASB59222.1    
 S101392_03961 (WaaJ)   Bacillus subtilis subsp. subtilis SRCM101392 ASB95405.1    
 S101444_03924 (WaaJ)   Bacillus subtilis subsp. subtilis SRCM101444 ARW00744.1    
 BSU38430 (GspA;YwaG) (possible fragment)   Bacillus subtilis subsp. subtilis str. 168 CAA51568.1
 BSUB_04081 (GspA)   Bacillus subtilis subsp. subtilis str. AG1839 AIC46557.1    
 I653_18860   Bacillus subtilis subsp. subtilis str. BAB-1 AGI31004.1    
 A7A1_2088   Bacillus subtilis subsp. subtilis str. BSP1 AGA22706.1    
 BSUA_04081 (GspA)   Bacillus subtilis subsp. subtilis str. JH642 substr. AG174 AIC42326.1    
 Q433_21160   Bacillus subtilis subsp. subtilis str. OH 131.1 AID00143.1    
 I33_3997   Bacillus subtilis subsp. subtilis str. RO-NN-1 AEP92903.1    
 BSSX_4042   Bacillus subtilis SX01705 ASK25906.1    
 A3772_20630   Bacillus subtilis SZMC 6179J AMS49413.1    
 BIS30_08980   Bacillus subtilis T30 AJW85289.1    
 CLD04_20030   Bacillus subtilis TLO3 ASZ63280.1    
 M036_19675   Bacillus subtilis TO-A AII37549.1    
 ABU16_0715   Bacillus subtilis TO-A JPC AKN11791.1    
 ABA10_19275   Bacillus subtilis UD1022 AKI94001.1    
 BKN48_08645   Bacillus subtilis VV2 AOY05402.1    
 C663_3754 (fragment)   Bacillus subtilis XF-1 AGE65458.1    
 B7P25_19025   Bacillus thuringiensis BM-BT15426 ARZ63776.1    
 B9C48_18225   Bacillus vallismortis NBIF-001 ARM29657.1    
 C0W57_16905   Bacillus velezensis 10075 AUS17760.1    
 CFN60_18625   Bacillus velezensis 157 ASK60284.1    
 BK055_19710   Bacillus velezensis 9912D APA04630.1    
 B7941_01420   Bacillus velezensis 9D-6 ARJ73260.1    
 CU084_20220   Bacillus velezensis AGVL-005 ATX85049.1    
 B938_18270   Bacillus velezensis AS43.3 AFZ92654.1    
 BMJ37_18220   Bacillus velezensis ATR2 ATU28588.1    
 BAMMD1_3486 (GspA)   Bacillus velezensis B25 CUX95375.1    
 BACAU_3588 (GspA)   Bacillus velezensis CAU B946 CCF07122.1    
 BCBMB205_37500 (fragment)   Bacillus velezensis CBMB205 ANF38632.1    
 AAV34_01230   Bacillus velezensis CBMB205 ARN85673.1    
 A1D33_010415   Bacillus velezensis CC09 ANB47709.1    
 CVD07_18505   Bacillus velezensis CN026 ATY30170.1    
 A2I97_17730   Bacillus velezensis D2-2 AOU02780.1    
 RBAM_035670   Bacillus velezensis FZB42 ABS75896.1 A7ZA70  
 ABH13_3732   Bacillus velezensis G341 AKL78306.1    
 B6257_08660   Bacillus velezensis GFP-2 AUJ60671.1    
 BVH55_19420   Bacillus velezensis GH1-13 AQS45943.1    
 BAGQ_3891 (fragment)   Bacillus velezensis GQJK49 ARZ60095.1    
 CJP14_19360   Bacillus velezensis J01 ASZ05866.1    
 AAV29_19070   Bacillus velezensis JJ-D34 AKF32535.1    
 NG74_03738 (GspA)   Bacillus velezensis JS25R AIU83744.1    
 BAJT_18215   Bacillus velezensis JTYP2 ARB35107.1    
 CRH11_03945   Bacillus velezensis L-1 ATO09226.1    
 CQJ38_18525   Bacillus velezensis LABIM40 ATL41380.1    
 A8142_17690   Bacillus velezensis LS69 ANU31904.1    
 CXP43_20115   Bacillus velezensis Lzh-a42 AUG37910.1    
 BBJ33_18420   Bacillus velezensis M75 AOO63422.1    
 BAPNAU_3761 (GspA)   Bacillus velezensis NAU-B3 CDH97541.1    
 AW02_036640 (RfaJ)   Bacillus velezensis NJN-6 AKD31812.1    
 BVS141_36820   Bacillus velezensis S141 BBA78176.1    
 A5891_17815   Bacillus velezensis S3-1 ANS40145.1    
 A6R78_16430   Bacillus velezensis SB1216 ANB85498.1    
 CHN56_02399 (GspA)   Bacillus velezensis SCDB 291 ASS62860.1    
 CLI97_01861 (GspA)   Bacillus velezensis SCGB 1 ATC51168.1    
 CLI98_01639 (GspA)   Bacillus velezensis SCGB 574 ATD74944.1    
 V529_38370 (GspA)   Bacillus velezensis SQR9 AHZ17863.1    
 S100072_03844 (WaaJ)   Bacillus velezensis SRCM100072 ASB55149.1    
 S101413_04244 (WaaJ)   Bacillus velezensis SRCM101413 ASB67660.1    
 BLL65_00865   Bacillus velezensis sx01604 AQZ71604.1    
 CEG11_18290   Bacillus velezensis T20E-257 ASF56937.1    
 CG798_04340   Bacillus velezensis TB1501 ASP24500.1    
 AJ82_20125   Bacillus velezensis TrigoCor1448 AHK51055.1    
 RBAU_3696 (GspA)   Bacillus velezensis UCMB5033 CDG31662.1    
 BAM5036_3487 (GspA)   Bacillus velezensis UCMB5036 CCP23493.1    
 BASU_3474 (GspA)   Bacillus velezensis UCMB5113 CDG27750.1    
 BANAU_3747 (GspA)   Bacillus velezensis YAU B9601-Y2 CCG51768.1    
 AAV30_01190   Bacillus velezensis YJ11-1-4 AKF74877.1    
 CGC64_04460   Bacteroides caccae ATCC 43185 ASM65285.1    
 ABI39_06210   Bacteroides dorei CL03T12C01 AND19078.1    
 EL88_03920   Bacteroides dorei isolate HS1_L1_B_010 AII62363.1    
 GV66_14555   Bacteroides dorei isolate HS1_L3_B_079 AII68844.1    
 IY41_14970   Bacteroides dorei isolate HS2_L_2_B_045b ALA74625.1    
 BF638R_4286   Bacteroides fragilis 638R CBW24706.1 E1WQT0  
 BF638R_0174   Bacteroides fragilis 638R CBW20782.1 E1WK61  
 MB0529_04140 (Gspa_2)   Bacteroides fragilis BE1 CUA20721.1    
 MB0529_00165 (Gspa_1)   Bacteroides fragilis BE1 CUA16831.1    
 VU15_00465   Bacteroides fragilis BOB25 AKA50335.1    
 VU15_20405   Bacteroides fragilis BOB25 AKA53811.1    

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