GlycosylTransferase Family 8

Activities in Familylipopolysaccharide α-1,3-galactosyltransferase (EC 2.4.1.44); UDP-Glc: (glucosyl)lipopolysaccharide α-1,2-glucosyltransferase (EC 2.4.1.-); lipopolysaccharide glucosyltransferase 1 (EC 2.4.1.58); glycogenin glucosyltransferase (EC 2.4.1.186); inositol 1-α-galactosyltransferase (galactinol synthase) (EC 2.4.1.123); homogalacturonan α-1,4-galacturonosyltransferase (EC 2.4.1.43); UDP-GlcA: xylan α-glucuronyltransferase (EC 2.4.1.-)
Mechanism Retaining
3D Structure StatusGT-A
NoteDistant similarity to family GT24; The animal LARGE bifunctional glycosyltransferases are made of two domains. The N-terminal domain, which adds a-1,3-Xyl residues, belongs to family GT8 while the C-terminal domain, which adds b-1,3-GlcA residues, belongs to family GT49.
External resourcesGlymap; HOMSTRAD;
Commercial Enzyme Provider(s)CHEMILY;
Statistics GenBank accession (10472); Uniprot accession (1210); PDB accession (43); 3D entries (9); cryst (0)
All (8862) Archaea (7) Bacteria (7385) Eukaryota (1318) Viruses (149) unclassified (3) Structure (9) Characterized (52)
| 1 | ... | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | ... | 74 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 KUB3006_C15490 (GspA)   Enterococcus faecalis KUB3006 BBD25123.1    
 KUB3007_C15470 (GspA)   Enterococcus faecalis KUB3007 BBD28164.1    
 KUB3007_C15460 (GspA)   Enterococcus faecalis KUB3007 BBD28163.1    
 BSG25_07755   Enterococcus faecalis L12 APE72741.1    
 BSG25_07760   Enterococcus faecalis L12 APE72742.1    
 BMT03_07520   Enterococcus faecalis L9 APC56074.1    
 BMT03_07515   Enterococcus faecalis L9 APC56073.1    
 A3777_03555   Enterococcus faecalis LD33 AMR94769.1    
 A3777_03550   Enterococcus faecalis LD33 AMR94768.1    
 A3777_03555   Enterococcus faecalis LD33 AMR94769.1    
 A3777_03550   Enterococcus faecalis LD33 AMR94768.1    
 OG1RF_11519 (Gspa1)   Enterococcus faecalis OG1RF AEA94206.1    
 OG1RF_11520 (Gspa2)   Enterococcus faecalis OG1RF AEA94207.1    
 A6B47_08130   Enterococcus faecalis sorialis ARV03814.1    
 A6B47_08135   Enterococcus faecalis sorialis ARV03815.1    
 EFS1_1619   Enterococcus faecalis str. Symbioflor 1 CCO72697.1    
 EFS1_1618 (fragment)   Enterococcus faecalis str. Symbioflor 1 CCO72696.1    
 DTO64_08785   Enterococcus faecalis TY1 AXG88653.1    
 DTO64_08780   Enterococcus faecalis TY1 AXG88652.1    
 GspA-1   Enterococcus faecalis V583 AAO81578.1
AAR59851.1
NP_815508.1
Q833W5  
 GspA-2   Enterococcus faecalis V583 AAO81579.1
AAR59852.1
NP_815509.1
Q833W4  
 EFW11_1466 (Gspα-1)   Enterococcus faecalis W11 BAV36705.1    
 EFW11_1467 (Gspα-2)   Enterococcus faecalis W11 BAV36706.1    
 pEfm12493_084 (fragment)   Enterococcus faecium AJY53568.1    
 EFE1002_1229   Enterococcus faecium CUX98707.1    
 EFE1002_1230   Enterococcus faecium CUX98708.1    
 Sequence 6686 from patent US 6583275   Enterococcus faecium AAQ46128.1
CVH53289.1
   
 Sequence 6172 from patent US 6583275   Enterococcus faecium AAQ45614.1
CVH53290.1
   
 CXH17_01285   Enterococcus faecium 13-009 AVJ41421.1    
 CXH17_01290   Enterococcus faecium 13-009 AVJ41422.1    
 CXR19_05695   Enterococcus faecium 13-022 AVJ45060.1    
 CXR19_05690   Enterococcus faecium 13-022 AVJ45059.1    
 CDL00_03050   Enterococcus faecium 16-346 ATU29410.1    
 CDL00_03055   Enterococcus faecium 16-346 ATU29411.1    
 AMR85_00825   Enterococcus faecium 64/3 ALF48636.1    
 AMR85_00830   Enterococcus faecium 64/3 ALF48637.1    
 AWJ25_06310   Enterococcus faecium 6E6 ALZ51877.1    
 AWJ25_06315   Enterococcus faecium 6E6 ALZ51878.1    
 BXT96_12805   Enterococcus faecium AALTL AUO62472.1    
 BXT96_12810   Enterococcus faecium AALTL AUO62473.1    
 BXT96_15655   Enterococcus faecium AALTL AUO63074.1    
 AX771_06945   Enterococcus faecium ATCC 700221 AMQ97275.1    
 AX771_06950   Enterococcus faecium ATCC 700221 AMQ97276.1    
 EFAU004_01481   Enterococcus faecium Aus0004 AFC63565.1    
 EFAU004_01482   Enterococcus faecium Aus0004 AFC63566.1    
 EFAU085_01516   Enterococcus faecium Aus0085 AGS75470.1    
 EFAU085_01517   Enterococcus faecium Aus0085 AGS75471.1    
 DPR13_04640   Enterococcus faecium BM4105-RF AWX47240.1    
 DPR13_06555   Enterococcus faecium BM4105-RF AWX47595.1    
 DPR13_06550   Enterococcus faecium BM4105-RF AWX47594.1    
 B6S05_07465   Enterococcus faecium CFSAN059070 AWV58432.1    
 B6S05_07460   Enterococcus faecium CFSAN059070 AWV58431.1    
 B6S06_07470   Enterococcus faecium CFSAN059071 AWV61449.1    
 B6S06_07465   Enterococcus faecium CFSAN059071 AWV61448.1    
 HMPREF0351_11489   Enterococcus faecium DO AFK59113.1    
 HMPREF0351_11490   Enterococcus faecium DO AFK59114.1    
 BO233_06470   Enterococcus faecium E1 APE40124.1    
 BO233_06475   Enterococcus faecium E1 APE40125.1    
 BK413_07205   Enterococcus faecium E232 ATW36234.1    
 BK413_07210   Enterococcus faecium E232 ATW36235.1    
 BK695_07210   Enterococcus faecium E240 ATU00271.1    
 BK695_07205   Enterococcus faecium E240 ATU00270.1    
 BK696_07200   Enterococcus faecium E243 ATU03220.1    
 BK696_07205   Enterococcus faecium E243 ATU03221.1    
 XM37_07130   Enterococcus faecium E39 ANB93915.1    
 XM37_07135   Enterococcus faecium E39 ANB93916.1    
 EfmE745_01664 (Gspa_1)   Enterococcus faecium E745 AOT78966.1    
 EfmE745_01665 (Gspa_2)   Enterococcus faecium E745 AOT78967.1    
 CO994_01456 (Gspa_2)   Enterococcus faecium Efaecium_ER04120.3A AUI18687.1    
 CO994_01455 (Gspa_1)   Enterococcus faecium Efaecium_ER04120.3A AUI18686.1    
 CO995_01455 (Gspa_2)   Enterococcus faecium Efaecium_ER04462.3A AUI21658.1    
 CO995_01454 (Gspa_1)   Enterococcus faecium Efaecium_ER04462.3A AUI21657.1    
 CO996_01455 (Gspa_1)   Enterococcus faecium Efaecium_ER04484.3A AUI24627.1    
 CO996_01456 (Gspa_2)   Enterococcus faecium Efaecium_ER04484.3A AUI24628.1    
 CO997_01461 (Gspa_1)   Enterococcus faecium Efaecium_ER04526.3A AUI33506.1    
 CO997_01462 (Gspa_2)   Enterococcus faecium Efaecium_ER04526.3A AUI33507.1    
 CO998_01454 (Gspa_1)   Enterococcus faecium Efaecium_ER04526.5A AUI27601.1    
 CO998_01455 (Gspa_2)   Enterococcus faecium Efaecium_ER04526.5A AUI27602.1    
 CEQ01_04840   Enterococcus faecium FDAARGOS_323 AVL44640.1    
 CEQ01_04845   Enterococcus faecium FDAARGOS_323 AVL44641.1    
 AL014_06590   Enterococcus faecium ISMMS_VRE_1 AOM15943.1    
 AL014_06585   Enterococcus faecium ISMMS_VRE_1 AOM15942.1    
 AL024_03930   Enterococcus faecium ISMMS_VRE_10 AOM36868.1    
 AL024_03925   Enterococcus faecium ISMMS_VRE_10 AOM36867.1    
 AL025_08200   Enterococcus faecium ISMMS_VRE_11 AON60853.1    
 AL025_08205   Enterococcus faecium ISMMS_VRE_11 AON60854.1    
 AL026_01555   Enterococcus faecium ISMMS_VRE_12 APV52878.1    
 AL026_09705   Enterococcus faecium ISMMS_VRE_12 APV54391.1    
 AL026_09700   Enterococcus faecium ISMMS_VRE_12 APV54390.1    
 AL015_08445   Enterococcus faecium ISMMS_VRE_2 AOM19300.1    
 AL015_08440   Enterococcus faecium ISMMS_VRE_2 AOM19299.1    
 AL016_01295   Enterococcus faecium ISMMS_VRE_3 AOM21080.1    
 AL016_01290   Enterococcus faecium ISMMS_VRE_3 AOM21079.1    
 AL016_14420   Enterococcus faecium ISMMS_VRE_3 AOM23580.1    
 AL017_07195   Enterococcus faecium ISMMS_VRE_4 AOM25237.1    
 AL017_07200   Enterococcus faecium ISMMS_VRE_4 AOM25238.1    
 AL018_08035   Enterococcus faecium ISMMS_VRE_5 AOM28382.1    
 AL018_14065   Enterococcus faecium ISMMS_VRE_5 AOM29582.1    
 AL018_08030   Enterococcus faecium ISMMS_VRE_5 AOM28381.1    
 AL020_04305   Enterococcus faecium ISMMS_VRE_7 AOM30655.1    
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