Activities in Sub Family	β-mannosidase (EC 3.2.1.25); Endo-β-1,4-mannanase (EC 3.2.1.78);
Mechanism	Retaining e
Clan	GH-A
3D Structure Status	( β / α ) 8 barrel
Catalytic Nucleophile/Base	Glu (experimental)
Catalytic Proton Donor	Glu (experimental)
Note	Once known as cellulase family A; many members have been assigned to subfamilies as described by Aspeborg et al. (2012) BMC Evol Biol. 12(1):186 (PMID: 22992189).
External resources	CAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)	MEGAZYME; NZYTech; PROZOMIX;
Statistics	GenBank accession (1559); Uniprot accession (72); PDB accession (29); 3D entries (11); cryst (0)

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Bacteria
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D	Subf
QQ984_09470		Bacillus licheniformis Jrh14-10	WIX00464.1			7
FTE28_02955		Bacillus licheniformis KS28	QNT71943.1			7
ICC24_09755		Bacillus licheniformis LCDD6	QPI23612.1			7
C1T27_09545		Bacillus licheniformis MBGJa67	AUZ30578.1			7
EYQ98_10200		Bacillus licheniformis MCC 2514	QBR20044.1			7
YdhT (fragment)		Bacillus licheniformis MD1	CAH10345.1			7
Q3B96_18075		Bacillus licheniformis MGMM9	WKU32067.1			7
Cel5D (Cel5D)		Bacillus licheniformis MSB03	ACY72383.1			7
NCTC10341_02012 (CelD)		Bacillus licheniformis NCTC10341	VEH78116.1			7
NCTC8721_01959 (CelD) (fragment)		Bacillus licheniformis NCTC8721	VEB18929.1			7
M8181_09060		Bacillus licheniformis NWMCC0042	WIY58163.1			7
LXN06_09090		Bacillus licheniformis NWMCC0046	UIN47819.1			7
H8Z86_09115		Bacillus licheniformis OK12	QNU02050.1			7
GII88_09240		Bacillus licheniformis P8_B2	QGI43305.1			7
CXG95_10800		Bacillus licheniformis PB3	AZN79546.1			7
B37_01402		Bacillus licheniformis SCCB 37	ARC73454.1			7
B14_02580		Bacillus licheniformis SCDB 14	ARC65578.1			7
B34_00222		Bacillus licheniformis SCDB 34	ARC67665.1			7
BaDB11_04389		Bacillus licheniformis SCK B11	ARC62952.1			7
S100141_01269		Bacillus licheniformis SRCM100141	ARW42591.1			7
EQY74_09950		Bacillus licheniformis SRCM103529	QAT53198.1			7
ETA57_09970		Bacillus licheniformis SRCM103583	QAW28884.1			7
ETK49_09655		Bacillus licheniformis SRCM103608	QAW37508.1			7
EQJ69_09630		Bacillus licheniformis SRCM103914	QAS16157.1			7
glycoside hydrolase (Gh5C)		Bacillus licheniformis SVD1	BAL45506.1			7
QKW34_09310		Bacillus licheniformis T5	WHF46346.1			7
C7M53_09515		Bacillus licheniformis TAB7	AYC51498.1			7
MUY_001894 (CelD)		Bacillus licheniformis WX-02	AKQ73026.1			7
OU809_09170		Bacillus paralicheniformis 285-3	WAJ16906.1			7
FLQ07_16450		Bacillus paralicheniformis A4-3	QEO07050.1			7
BaLi_c19170 (CelD)		Bacillus paralicheniformis ATCC 9945a	AGN36285.1			7
RZN08_09985		Bacillus paralicheniformis BC20	WOH92953.1			7
SC10_B2orf02858 (fragment)		Bacillus paralicheniformis BL-09	AJO18131.1			7
D5285_09575		Bacillus paralicheniformis CBMAI 1303	AYQ16315.1			7
QNH18_09325		Bacillus paralicheniformis CEW 1W	WHX88460.1			7
RFN66_10165		Bacillus paralicheniformis CP47	WMW49269.1			7
QN340_12565		Bacillus paralicheniformis DY4	WIG05837.1			7
K8336_04710		Bacillus paralicheniformis ES-1	UAY71380.1			7
D2B33_11185		Bacillus paralicheniformis FA6	QFY38925.1			7
KY997_10360		Bacillus paralicheniformis HAS-1	UAL16319.2 UAL16319.1			7
BLMD_09340		Bacillus paralicheniformis MDJK30	ARA85657.1			7
N2384_22120		Bacillus paralicheniformis NG-ABK-31	UWS60646.1			7
RSC1_02744		Bacillus paralicheniformis RSC-1	BCE06587.1			7
RSC2_00176		Bacillus paralicheniformis RSC-2	BCE08380.1			7
RSC3_01826		Bacillus paralicheniformis RSC-3	BCE14470.1			7
P3X35_09120		Bacillus paralicheniformis SYN-191	WFF95645.1			7
KY998_06285		Bacillus paralicheniformis TXO7B-1SG6	UAL27261.1			7
KJS96_009205		Bacillus paralicheniformis VITHBRA024	UCU91497.1			7
G3M81_09630		Bacillus paralicheniformis ZAP17	QII48993.1			7
C5Y82_07945		Bacillus pumilus 150a	AVI40951.1			7
GZ55_13460		Bacillus pumilus 3-19	QKN78740.1			7
N7921_08910		Bacillus pumilus 33.4	UXO89776.1			7
DJ67_013510		Bacillus pumilus 7P	QLI45299.1			7
LG401_07910		Bacillus pumilus AR03	UCZ72423.1			7
QNH35_08885		Bacillus pumilus B2_10	WHX46576.1			7
LG951_08295		Bacillus pumilus BIM 171	UDF18178.1			7
VP59_07445		Bacillus pumilus C4	ANT56640.1			7
K4A85_01905		Bacillus pumilus EB130	QZD59784.1			7
R0I01_02000		Bacillus pumilus EB68	WOP22253.1			7
Q8W18_08365		Bacillus pumilus F12-21	WLP61234.1			7
β-mannanase		Bacillus pumilus GBSW 19	AHF81566.1			7
BS467_15785		Bacillus pumilus GLB197	APP17114.1			7
ID12_13295		Bacillus pumilus GR-8	AKU32339.1			7
ASM07_07620		Bacillus pumilus ku-bf1	AMB89777.1			7
QPL77_07980		Bacillus pumilus Monterrey_S2	WIG33586.1			7
MK860_08080		Bacillus pumilus MS32	WFO49112.1			7
BW16_08670		Bacillus pumilus MTCC B6033	AHL71452.1			7
SAMEA4076707_01656		Bacillus pumilus NCTC10337	SNV02448.1			7
NPA43_07930		Bacillus pumilus NDY-10	UUD44160.1			7
AKO65_15415		Bacillus pumilus NJ-M2	ALM29338.1			7
AKO66_11740		Bacillus pumilus NJ-V	ANY97356.1			7
AMR71_11735		Bacillus pumilus NJ-V2	ALM45875.1			7
H9S87_07710		Bacillus pumilus ONU 554	QNP17861.1			7
BEN31_07990		Bacillus pumilus PDSLzg-1	AOC56743.1			7
WAA16_07920		Bacillus pumilus S9	WWZ72963.1			7
BPUM_1561		Bacillus pumilus SAFR-032	ABV62243.1			7
GPS65_08550		Bacillus pumilus SF-4	QHQ76169.1			7
UP15_08390		Bacillus pumilus SH-B11	AMM88977.1			7
UP12_08105		Bacillus pumilus SH-B9	AMM97310.1			7
BTUAT1_15770		Bacillus pumilus TUAT1	BAT48711.1			7
HZ310_11005		Bacillus pumilus UAMX	QLI78307.1			7
VT48_08320		Bacillus pumilus W3	AKC66023.1			7
DKE43_04285		Bacillus pumilus ZB201701	AZV52369.1			7
NIZ90_07965		Bacillus safensis 1370ba1	USY30674.1			7
M5E03_08360		Bacillus safensis AHB11	USD80685.1			7
M5E02_08020		Bacillus safensis AHB2	USD84333.1			7
BWL10_15385		Bacillus safensis BcP62	UDB50681.1			7
B0X07_00650		Bacillus safensis Bcs96	UDB47719.1			7
EI692_07830		Bacillus safensis BLXSC	UQZ92883.1			7
BRL64_08220		Bacillus safensis BRM1	ARD56165.1			7
ORQ91_02180		Bacillus safensis BS-10L	WBL29606.1			7
QNH21_08110		Bacillus safensis CEW AP102	WHX84357.1			7
QNH25_08125		Bacillus safensis CEW-AP100	WHX76900.1			7
WNC56_08410		Bacillus safensis DMB13	WYZ12158.1			7
JNE45_08115		Bacillus safensis F6	QRF33821.1			7
RS87_08150		Bacillus safensis FO-36b	AWI36699.1			7
N4Q31_08195		Bacillus safensis GX-H6	UXC34024.1			7
LXN49_08095		Bacillus safensis H31R-08	UIN51756.1			7
BsIDN1_30480 (fragment)		Bacillus safensis IDN1	BBP89430.1			7
V9W59_08345		Bacillus safensis JJ1041	WWY46181.1			7
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