Glycoside Hydrolase Family 5 / Subf 7

Activities in Familyendo-β-1,4-glucanase / cellulase (EC 3.2.1.4); endo-β-1,4-xylanase (EC 3.2.1.8); β-glucosidase (EC 3.2.1.21); β-mannosidase (EC 3.2.1.25); β-glucosylceramidase (EC 3.2.1.45); glucan β-1,3-glucosidase (EC 3.2.1.58); exo-β-1,4-glucanase / cellodextrinase (EC 3.2.1.74); glucan endo-1,6-β-glucosidase (EC 3.2.1.75); mannan endo-β-1,4-mannosidase (EC 3.2.1.78); cellulose β-1,4-cellobiosidase (EC 3.2.1.91); steryl β-glucosidase (EC 3.2.1.104); endoglycoceramidase (EC 3.2.1.123); chitosanase (EC 3.2.1.132); β-primeverosidase (EC 3.2.1.149); xyloglucan-specific endo-β-1,4-glucanase (EC 3.2.1.151); endo-β-1,6-galactanase (EC 3.2.1.164); β-1,3-mannanase (EC 3.2.1.-); arabinoxylan-specific endo-β-1,4-xylanase (EC 3.2.1.-); mannan transglycosylase (EC 2.4.1.-); lichenase / endo-β-1,3-1,4-glucanase (EC 3.2.1.73); β-glycosidase (EC 3.2.1.-); endo-β-1,3-glucanase / laminarinase (EC 3.2.1.39); β-N-acetylhexosaminidase (EC 3.2.1.52); chitosanase (EC 3.2.1.132); β-D-galactofuranosidase (EC 3.2.1.146); β-galactosylceramidase (EC 3.2.1.46);
Activities in Sub Family
Mechanism Retaining
ClanGH-A
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental)
NoteOnce known as cellulase family A; many members have been assigned to subfamilies as described by Aspeborg et al. (2012) BMC Evol Biol. 12(1):186 (PMID: 22992189).
External resourcesCAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; NZYTech; PROZOMIX;
Statistics GenBank accession (707); Uniprot accession (158); PDB accession (26); 3D entries (10); cryst (0)
| 1 | 2 | 3 |
Bacteria
Protein Name EC#Organism GenBankUniprotPDB/3DSubf
 NCTC10172_01384   Acholeplasma hippikon NCTC10172 VEU83309.1     7
 β-mannanase (ManA) 3.2.1.78 Acidothermus cellulolyticus ABJ41262.1
ABJ41263.1
ABJ41266.1
    7
 mannanase (Acel_0616)   Acidothermus cellulolyticus 11B ABK52389.1 A0LSH9   7
 SAMN04489717_0883   Actinopolymorpha singaporensis DSM 22024 SDR87823.1     7
 A3BBH6_12770   Alistipes sp. 3BBH6 BBL01041.1     7
 A5CPEGH6_09140   Alistipes sp. 5CPEGH6 BBL06276.1     7
 D1815_10480   Aquimarina sp. AD1 AXT56158.1     7
 D1816_19590   Aquimarina sp. AD10 AXT62471.1     7
 D1818_21435   Aquimarina sp. BL5 AXT53265.1     7
 E0W69_014625   Arachidicoccus sp. B3-10 QES89840.1     7
 AA314_01832   Archangium gephyra DSM 2261 AKJ00206.1     7
 Astex_2880   Asticcacaulis excentricus CB 48 ADU14517.1 C5SNP2   7
 EM6_2786   Asticcacaulis excentricus M6 BBF82157.1     7
 BAE_15700   Bacillus aerophilus 232 QAR54176.1     7
 EVS87_008175   Bacillus altitudinis CHB19 QEO62178.1     7
 D0438_04060   Bacillus altitudinis Cr2-1 QDZ94129.1     7
 BPGQ101_08710   Bacillus altitudinis GQYP101 QCU18939.1     7
 CSE15_08310   Bacillus altitudinis P-10 ATP93954.1     7
 CFN77_08490   Bacillus altitudinis SGAir0031 ATH72233.1     7
 BGLY_1877   Bacillus glycinifermentans SCA85700.1     7
 EQZ20_09650   Bacillus glycinifermentans SRCM103574 QAT65157.1     7
 BLDA23_10220   Bacillus licheniformis 0DA23-1 AXF88643.1     7
 BL14DL4_04369   Bacillus licheniformis 14ADL4 AVI49506.1     7
 EJ992_09520   Bacillus licheniformis ATCC 14580 QCX99206.1     7
 CPQ91_09265   Bacillus licheniformis ATCC 9789 ATI76022.1     7
 BL1202_02035   Bacillus licheniformis BL1202 AOP14983.1     7
 CD200_09505   Bacillus licheniformis CBA7132 AWV40657.1     7
 BLCSL_09220   Bacillus licheniformis CSL2 QDF79002.1     7
 BLi01883 / BL01229   Bacillus licheniformis DSM 13 = ATCC 14580 AAU40778.1
AAU23418.1
Q65JI6   7
 AB684_08875   Bacillus licheniformis HRBL-15TDI7 AMR10288.1     7
 C1T27_09545   Bacillus licheniformis MBGJa67 AUZ30578.1     7
 EYQ98_10200   Bacillus licheniformis MCC 2514 QBR20044.1     7
 YdhT (fragment)   Bacillus licheniformis MD1 CAH10345.1 Q5K2L9   7
 Cel5D (Cel5D)   Bacillus licheniformis MSB03 ACY72383.1 D1L8C8   7
 NCTC10341_02012 (CelD)   Bacillus licheniformis NCTC10341 VEH78116.1     7
 NCTC8721_01959 (CelD) (fragment)   Bacillus licheniformis NCTC8721 VEB18929.1     7
 CXG95_10800   Bacillus licheniformis PB3 AZN79546.1     7
 B37_01402   Bacillus licheniformis SCCB 37 ARC73454.1     7
 B14_02580   Bacillus licheniformis SCDB 14 ARC65578.1     7
 B34_00222   Bacillus licheniformis SCDB 34 ARC67665.1     7
 BaDB11_04389   Bacillus licheniformis SCK B11 ARC62952.1     7
 S100141_01269   Bacillus licheniformis SRCM100141 ARW42591.1     7
 EQY74_09950   Bacillus licheniformis SRCM103529 QAT53198.1     7
 ETA57_09970   Bacillus licheniformis SRCM103583 QAW28884.1     7
 ETK49_09655   Bacillus licheniformis SRCM103608 QAW37508.1     7
 EQJ69_09630   Bacillus licheniformis SRCM103914 QAS16157.1     7
 glycoside hydrolase (Gh5C)   Bacillus licheniformis SVD1 BAL45506.1     7
 C7M53_09515   Bacillus licheniformis TAB7 AYC51498.1     7
 MUY_001894 (CelD)   Bacillus licheniformis WX-02 AKQ73026.1     7
 FLQ07_16450   Bacillus paralicheniformis A4-3 QEO07050.1     7
 BaLi_c19170 (CelD)   Bacillus paralicheniformis ATCC 9945a AGN36285.1     7
 SC10_B2orf02858 (fragment)   Bacillus paralicheniformis BL-09 AJO18131.1     7
 D5285_09575   Bacillus paralicheniformis CBMAI 1303 AYQ16315.1     7
 BLMD_09340   Bacillus paralicheniformis MDJK30 ARA85657.1     7
 C5Y82_07945   Bacillus pumilus 150a AVI40951.1     7
 VP59_07445   Bacillus pumilus C4 ANT56640.1     7
 β-mannanase   Bacillus pumilus GBSW 19 AHF81566.1     7
 BS467_15785   Bacillus pumilus GLB197 APP17114.1     7
 ID12_13295   Bacillus pumilus GR-8 AKU32339.1     7
 ASM07_07620   Bacillus pumilus ku-bf1 AMB89777.1     7
 BW16_08670   Bacillus pumilus MTCC B6033 AHL71452.1     7
 SAMEA4076707_01656   Bacillus pumilus NCTC10337 SNV02448.1     7
 AKO65_15415   Bacillus pumilus NJ-M2 ALM29338.1     7
 AKO66_11740   Bacillus pumilus NJ-V ANY97356.1     7
 AMR71_11735   Bacillus pumilus NJ-V2 ALM45875.1     7
 BEN31_07990   Bacillus pumilus PDSLzg-1 AOC56743.1     7
 BPUM_1561   Bacillus pumilus SAFR-032 ABV62243.1 A8FDC6   7
 UP15_08390   Bacillus pumilus SH-B11 AMM88977.1     7
 UP12_08105   Bacillus pumilus SH-B9 AMM97310.1     7
 BTUAT1_15770   Bacillus pumilus TUAT1 BAT48711.1     7
 VT48_08320   Bacillus pumilus W3 AKC66023.1     7
 DKE43_04285   Bacillus pumilus ZB201701 AZV52369.1     7
 BRL64_08220   Bacillus safensis BRM1 ARD56165.1     7
 RS87_08150   Bacillus safensis FO-36b AWI36699.1     7
 BSL056_08100   Bacillus safensis KCTC 12796BP APJ10920.1     7
 FX981_03751   Bacillus safensis PgKB20 QEK65481.1     7
 CS953_10685   Bacillus safensis sami AYJ90157.1     7
 BSA145_16070   Bacillus safensis U14-5 APT47251.1     7
 BSA171_11305   Bacillus safensis U17-1 APT54133.1     7
 BSA41_06410   Bacillus safensis U41 APT49591.1     7
 S101395_03069   Bacillus sonorensis SRCM101395 ASB89576.1     7
 CJO35_09290   Bacillus sp. 1s-1 ASV15341.1     7
 BSZ43_09220   Bacillus sp. H15-1 APJ26961.1     7
 glycosyl hydrolase family 5 mannanase precursor (ManA)   Bacillus sp. HJ14 AHH02586.2
AHH02586.1
    7
 C1T29_10825 (fragment)   Bacillus sp. MBGLi79 AUZ38770.1     7
 QR42_07965   Bacillus sp. WP8 AIZ60203.1     7
 BK049_00270   Bacillus xiamenensis VV3 AOZ87243.1     7
 BRDCF_09535   Bacteroidales bacterium CF AGX08895.1
AGY54507.1
    7
 BcellWH2_02031   Bacteroides cellulosilyticus WH2 ALJ59276.1     7
 EL88_18305   Bacteroides dorei isolate HS1_L1_B_010 AII64978.1     7
 BF638R_0823   Bacteroides fragilis 638R CBW21396.1 E1WLN2   7
 MB0529_00763   Bacteroides fragilis BE1 CUA17419.1     7
 VU15_03540   Bacteroides fragilis BOB25 AKA54083.1     7
 E0L14_08080   Bacteroides fragilis CCUG4856T QCT77359.1     7
 EC81_008315   Bacteroides fragilis DCMOUH0017B QCQ53807.1     7
 EE52_007650   Bacteroides fragilis DCMOUH0018B QCQ49303.1     7
 HR50_007820   Bacteroides fragilis DCMOUH0042B QCQ40509.1     7
 IA74_007305   Bacteroides fragilis DCMOUH0067B QCQ35920.1     7
 IB64_008315   Bacteroides fragilis DCMOUH0085B QCQ31640.1     7
 EC80_008290   Bacteroides fragilis DCMSKEJBY0001B QCQ44843.1     7
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