Activities in Sub Family	Endo-β-1,4-glucanase (EC 3.2.1.4);
Mechanism	Retaining e
Clan	GH-A
3D Structure Status	( β / α ) 8 barrel
Catalytic Nucleophile/Base	Glu (experimental)
Catalytic Proton Donor	Glu (experimental)
Note	Once known as cellulase family A; many members have been assigned to subfamilies as described by Aspeborg et al. (2012) BMC Evol Biol. 12(1):186 (PMID: 22992189).
External resources	CAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)	MEGAZYME; NZYTech; PROZOMIX;
Statistics	GenBank accession (2130); Uniprot accession (61); PDB accession (35); 3D entries (9); cryst (0)

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Eukaryota
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D	Subf
381391		Chalara longipes (Chalo1)				5
343981		Chalara longipes (Chalo1)				5
348418		Chalara longipes (Chalo1)				5
408928		Chalara longipes (Chalo1)				5
425411		Chalara longipes (Chalo1)				5
425722		Chalara longipes (Chalo1)				5
479485		Chalara longipes (Chalo1)				5
395231		Chalara longipes (Chalo1)				5
1670390		Choiromyces venosus 120613-1 (Chove1)				5
cellulase (CelA;CsCelA)	3.2.1.4	Ciboria shiraiana	AIC79156.1	A0A068B5I5		5
918124		Cladochytrium polystomum WB228 (Clapol1_1)				5
838142		Cladochytrium polystomum WB228 (Clapol1_1)				5
489416		Cladochytrium replicatum JEL 714 v1.0 (Clarep1_1)				5
489658		Cladochytrium replicatum JEL 714 v1.0 (Clarep1_1)				5
791247		Cladochytrium replicatum JEL 714 v1.0 (Clarep1_1)				5
752365		Cladochytrium replicatum JEL 714 v1.0 (Clarep1_1)				5
6318		Cladonia grayi Cgr/DA2myc/ss v2.0 (Clagr3)				5
194344		Passalora fulva v1 (Clafu1)				5
190917		Passalora fulva v1 (Clafu1)				5
glycoside hydrolase family 5 endoglucanase, partial (fragment)		Cladosporium sp. 0629-033 2 WA Aa/MF06-304	CDL74329.1			5
3377		Cladosporium sphaerospermum UM 843 (Clasph1)				5
5381		Cladosporium sphaerospermum UM 843 (Clasph1)				5
423546		Clathrospora elynae CBS 161.51 v1 (Clael1)				5
3691		Claviceps purpurea 20.1 (Clapu1)				5
1675293		Clitocybe gibba IJFM A808 v1.0 (Cligib1)				5
576231		Clitocybe gibba IJFM A808 v1.0 (Cligib1)				5
48560		Clitocybe gibba IJFM A808 v1.0 (Cligib1)				5
1676529		Clitocybe gibba IJFM A808 v1.0 (Cligib1)				5
473194		Clohesyomyces aquaticus v1.0 (Cloaq1)				5
491986		Clohesyomyces aquaticus v1.0 (Cloaq1)				5
482841		Clohesyomyces aquaticus v1.0 (Cloaq1)				5
607399		Clohesyomyces aquaticus v1.0 (Cloaq1)				5
ORF (fragment)		Clonostachys rosea 0628-013 3 PDA/MF06-095	CDL74338.1			5
Eg8-20		Clonostachys rosea f. catenulata HL-1-1	AFK10489.1			5
174790		Cochliobolus heterostrophus C4 v6.0 (CocheC4_6)				5
275116		Cochliobolus heterostrophus C4 v6.0 (CocheC4_6)				5
268314		Cochliobolus heterostrophus HAW225 v4.0 (ChetHAW225_4)				5
179747		Cochliobolus heterostrophus HAW225 v4.0 (ChetHAW225_4)				5
4055		Cochliobolus heterostrophus Hm540 (ChetHm540_1)				5
6448		Cochliobolus heterostrophus Hm540 (ChetHm540_1)				5
170853		Cochliobolus heterostrophus PR9b v4.0 (ChetPR9b_4)				5
267401		Cochliobolus heterostrophus PR9b v4.0 (ChetPR9b_4)				5
222726		Cochliobolus sativus ND90Pr (Cocsa1)				5
126645		Cochliobolus sativus ND90Pr (Cocsa1)				5
7803		Colletotrichum chlorophyti NTL11 (Colch1)				5
3383		Colletotrichum chlorophyti NTL11 (Colch1)				5
8595		Colletotrichum chlorophyti NTL11 (Colch1)				5
8689		Colletotrichum chlorophyti NTL11 (Colch1)				5
ORF (fragment)		Colletotrichum coccodes 0629-022 1 A PDA/MF06-283	CDL74331.1			5
ORF (fragment)		Colletotrichum coccodes 0629-022 1 A PDA/MF06-283	CDL74332.1			5
CDEST_07547		Colletotrichum destructivum CBS 520.97	WQF82533.1			5
CDEST_11903		Colletotrichum destructivum CBS 520.97	WQF86889.1			5
CDEST_01459		Colletotrichum destructivum CBS 520.97	WQF76445.1			5
CDEST_00254		Colletotrichum destructivum CBS 520.97	WQF75240.1			5
279094		Colletotrichum fioriniae PJ7 (Colfi1)				5
280955		Colletotrichum fioriniae PJ7 (Colfi1)				5
279241		Colletotrichum fioriniae PJ7 (Colfi1)				5
277651		Colletotrichum fioriniae PJ7 (Colfi1)				5
CGRA01v4_01929		Colletotrichum graminicola isolate M1.001	WDK10650.1			5
CGRA01v4_07992		Colletotrichum graminicola isolate M1.001	WDK16709.1			5
CGRA01v4_02110		Colletotrichum graminicola isolate M1.001	WDK10831.1			5
12178		Colletotrichum higginsianum IMI 349063 (Colhig2)				5
3239		Colletotrichum higginsianum IMI 349063 (Colhig2)				5
6646		Colletotrichum higginsianum IMI 349063 (Colhig2)				5
4344		Colletotrichum higginsianum IMI 349063 (Colhig2)				5
942		Colletotrichum incanum (Colin1)				5
11630		Colletotrichum incanum (Colin1)				5
9050		Colletotrichum incanum (Colin1)				5
1279		Colletotrichum incanum (Colin1)				5
EsH8_II_000738		Colletotrichum jinshuiense	WYZ37232.1			5
EsH8_VII_001010		Colletotrichum jinshuiense	WYZ44574.1			5
EsH8_IV_000205		Colletotrichum jinshuiense	WYZ39864.1			5
CLUP02_04230		Colletotrichum lupini IMI 504893	UQC78753.1			5
CLUP02_02689		Colletotrichum lupini IMI 504893	UQC77222.1			5
CLUP02_13197		Colletotrichum lupini IMI 504893	UQC87678.1			5
CLUP02_02319		Colletotrichum lupini IMI 504893	UQC75663.1			5
1019326		Colletotrichum nymphaeae SA-01 (Colny1)				5
1017430		Colletotrichum nymphaeae SA-01 (Colny1)				5
1011337		Colletotrichum nymphaeae SA-01 (Colny1)				5
1008339		Colletotrichum nymphaeae SA-01 (Colny1)				5
145686		Colletotrichum orbiculare 104-T (Colorb1)				5
138236		Colletotrichum orbiculare 104-T (Colorb1)				5
136345		Colletotrichum orbiculare 104-T (Colorb1)				5
144865		Colletotrichum orbiculare 104-T (Colorb1)				5
4325		Colletotrichum orchidophilum IMI 309357 (Color1)				5
10110		Colletotrichum orchidophilum IMI 309357 (Color1)				5
9284		Colletotrichum orchidophilum IMI 309357 (Color1)				5
7764		Colletotrichum orchidophilum IMI 309357 (Color1)				5
941793		Colletotrichum salicis CBS607.94 (Colsa1)				5
939121		Colletotrichum salicis CBS607.94 (Colsa1)				5
942535		Colletotrichum salicis CBS607.94 (Colsa1)				5
947537		Colletotrichum salicis CBS607.94 (Colsa1)				5
981349		Colletotrichum simmondsii CBS122122 (Colsi1)				5
983858		Colletotrichum simmondsii CBS122122 (Colsi1)				5
977228		Colletotrichum simmondsii CBS122122 (Colsi1)				5
980680		Colletotrichum simmondsii CBS122122 (Colsi1)				5
3188		Colletotrichum sublineola TX430BB (Colsub1)				5
165		Colletotrichum sublineola TX430BB (Colsub1)				5
143		Colletotrichum sublineola TX430BB (Colsub1)				5
1695		Colletotrichum sublineola TX430BB (Colsub1)				5
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