Activities in Sub Family	Endo-β-1,4-glucanase (EC 3.2.1.4);
Mechanism	Retaining e
Clan	GH-A
3D Structure Status	( β / α ) 8 barrel
Catalytic Nucleophile/Base	Glu (experimental)
Catalytic Proton Donor	Glu (experimental)
Note	Once known as cellulase family A; many members have been assigned to subfamilies as described by Aspeborg et al. (2012) BMC Evol Biol. 12(1):186 (PMID: 22992189).
External resources	CAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)	MEGAZYME; NZYTech; PROZOMIX;
Statistics	GenBank accession (2125); Uniprot accession (61); PDB accession (35); 3D entries (9); cryst (0)

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Eukaryota
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D	Subf
771		Armillaria mellea DSM 3731 (Armme1_1)				5
1134664		Armillaria mellea ELDO17 v1.0 (Armmel1)				5
624211		Armillaria nabsnona CMW6904 v1.0 (Armnab1)				5
1563701		Armillaria novae-zelandiae 2840 v1.0 (Armnov1)				5
253102		Armillaria ostoyae C18/9 (Armosto1)				5
55999		Armillaria tabescens CCBAS 213 v1.0 (Armtab1)				5
8331		Arthrobotrys oligospora ATCC 24927 (Artol1)				5
4377		Arthrobotrys oligospora ATCC 24927 (Artol1)				5
5192		Arthrobotrys oligospora ATCC 24927 (Artol1)				5
6444		Arthrobotrys oligospora ATCC 24927 (Artol1)				5
9033		Arthrobotrys oligospora ATCC 24927 (Artol1)				5
glycosyl hydrolase family 5, partial		Arthrobotrys sp. CX1	QNH74676.1			5
464689		Artolenzites elegans CIRM-BRFM 1122 v1.0 (Artele1122_1)				5
211252		Artolenzites elegans CIRM-BRFM 1122 v1.0 (Artele1122_1)				5
1841137		Clavicorona pyxidata HHB10654 v1 (Clapy1)				5
1875656		Clavicorona pyxidata HHB10654 v1 (Clapy1)				5
1294112		Clavicorona pyxidata HHB10654 v1 (Clapy1)				5
EKO05_0007283		Ascochyta rabiei isolate Me14	UPX16902.1			5
EKO05_0010835		Ascochyta rabiei isolate Me14	UPX20607.1			5
4781		Ascocoryne sarcoides NRRL50072 (Ascsa1)				5
3701		Ascocoryne sarcoides NRRL50072 (Ascsa1)				5
6356		Ascocoryne sarcoides NRRL50072 (Ascsa1)				5
7011		Ascocoryne sarcoides NRRL50072 (Ascsa1)				5
6156		Ascocoryne sarcoides NRRL50072 (Ascsa1)				5
3291		Ascocoryne sarcoides NRRL50072 (Ascsa1)				5
8760		Ascocoryne sarcoides NRRL50072 (Ascsa1)				5
9171		Ascocoryne sarcoides NRRL50072 (Ascsa1)				5
endoglucanase II		Aspergillus aculeatus	AAN16396.1 AAN75019.1			5
endoglucanase 2 (Cmc2;FII-CMCase;FII CM-cellulase)		Aspergillus aculeatus F-50	BAA29030.1			5
endo-β-1,4-glucanase V (FV CM-cellulase;Cel1)		Aspergillus aculeatus WO 94/14953	AAC08587.1			5
31344		Aspergillus albertensis v1.0 (Aspalbe1)				5
180118		Aspergillus albertensis v1.0 (Aspalbe1)				5
188793		Aspergillus albertensis v1.0 (Aspalbe1)				5
315130		Aspergillus alliaceus CBS 536.65 v1.0 (Aspalli1)				5
316526		Aspergillus alliaceus CBS 536.65 v1.0 (Aspalli1)				5
165936		Aspergillus alliaceus CBS 536.65 v1.0 (Aspalli1)				5
88676		Aspergillus arachidicola v1.0 (Aspara19utr)				5
165658		Aspergillus arachidicola v1.0 (Aspara19utr)				5
166504		Aspergillus avenaceus IBT 18842 v1.0 (Aspave1)				5
172136		Aspergillus avenaceus IBT 18842 v1.0 (Aspave1)				5
280702		Aspergillus bertholletius IBT 29228 v1.0 (Aspber1)				5
299071		Aspergillus bertholletius IBT 29228 v1.0 (Aspber1)				5
2581		Aspergillus bombycis NRRL 26010 (Aspbom1)				5
3868		Aspergillus bombycis NRRL 26010 (Aspbom1)				5
30120		Aspergillus brasiliensis v1 (Aspbr1)				5
124037		Aspergillus brasiliensis v1 (Aspbr1)				5
146443		Aspergillus brasiliensis v1 (Aspbr1)				5
106784		Aspergillus caelatus CBS 763.97 v1.0 (Aspcae1)				5
162611		Aspergillus caelatus CBS 763.97 v1.0 (Aspcae1)				5
769993		Aspergillus calidoustus (Aspcal1)				5
763399		Aspergillus calidoustus (Aspcal1)				5
759891		Aspergillus calidoustus (Aspcal1)				5
320093		Aspergillus campestris IBT 28561 v1 (Aspcam1)				5
315371		Aspergillus campestris IBT 28561 v1 (Aspcam1)				5
307914		Aspergillus campestris IBT 28561 v1 (Aspcam1)				5
130878		Aspergillus candidus CBS 102.13 v1.0 (Aspcand1)				5
16349		Aspergillus candidus CBS 102.13 v1.0 (Aspcand1)				5
134719		Aspergillus candidus CBS 102.13 v1.0 (Aspcand1)				5
130813		Aspergillus carbonarius ITEM 5010 v3 (Aspca3)				5
207459		Aspergillus carbonarius ITEM 5010 v3 (Aspca3)				5
206627		Aspergillus carbonarius ITEM 5010 v3 (Aspca3)				5
ACHE_40697S		Aspergillus chevalieri M1	BCR88133.1			5
8484		Aspergillus clavatus NRRL 1 (Aspcl1)				5
8516		Aspergillus clavatus NRRL 1 (Aspcl1)				5
8871		Aspergillus clavatus NRRL 1 (Aspcl1)				5
164574		Aspergillus coremiiformis CBS 553.77 v1.0 (Aspcor1)				5
164772		Aspergillus coremiiformis CBS 553.77 v1.0 (Aspcor1)				5
2657		Aspergillus cristatus GZAAS20.1005 (Aspcri1)				5
G4B11_010939		Aspergillus flavus AF13	QMW47460.1			5
G4B11_000751		Aspergillus flavus AF13	QMW37515.1			5
endo-1,4-β-glucanase, partial (fragment)		Aspergillus flavus AGERI-S4	BBE15448.1			5
AFCA_000749		Aspergillus flavus CA14	UCK57867.1			5
AFCA_011740		Aspergillus flavus CA14	UDD64503.1			5
AFCA_011740 (fragment)		Aspergillus flavus CA14	UDD64504.1			5
F9C07_1565		Aspergillus flavus NRRL 3357	QRD88581.1			5
F9C07_5856		Aspergillus flavus NRRL 3357	QRD91813.1			5
G4B84_000691		Aspergillus flavus NRRL3357	QMW25446.1			5
G4B84_010889		Aspergillus flavus NRRL3357	QMW35398.1			5
30777		Aspergillus flavus NRRL3357 (Aspfl1)				5
35267		Aspergillus flavus NRRL3357 (Aspfl1)				5
1565		Aspergillus flavus NRRL3357 v1.0 (Aspfl2_3)				5
5856		Aspergillus flavus NRRL3357 v1.0 (Aspfl2_3)				5
101639		Aspergillus fumigatus A1163 (Aspfu_A1163_1)				5
107389		Aspergillus fumigatus A1163 (Aspfu_A1163_1)				5
106300		Aspergillus fumigatus A1163 (Aspfu_A1163_1)				5
106714		Aspergillus fumigatus A1163 (Aspfu_A1163_1)				5
8226		Aspergillus fumigatus Af293 (Aspfu1)				5
7824		Aspergillus fumigatus Af293 (Aspfu1)				5
2453		Aspergillus fumigatus Af293 (Aspfu1)				5
9343		Aspergillus fumigatus Af293 (Aspfu1)				5
endoglucanase (CenA)		Aspergillus fumigatus WL002	AOY41714.1			5
endoglucanase / cellulase (Egl2)	3.2.1.4	Aspergillus fumigatus Z5	ADX78144.1	F1DGF4		5
endoglucanase / cellulase (Egl3)	3.2.1.4	Aspergillus fumigatus Z5	ADX78145.1	F1DGF5		5
glycoside hydrolase family 5		Aspergillus glaucus CCHA	AVM41566.1			5
68490		Aspergillus glaucus v1 (Aspgl1)				5
endo-β-1,4-glucanase C (EglC) (Cel5B)		Aspergillus kawachii	BAB62319.1			5
endo-β-1,4-glucanase A (EglA) (Cel5A)	3.2.1.4	Aspergillus kawachii	BAB62317.1	Q96WR0		5
15086		Aspergillus kawachii IFO 4308 (Aspka1_1)				5
16893		Aspergillus kawachii IFO 4308 (Aspka1_1)				5
14756		Aspergillus kawachii IFO 4308 (Aspka1_1)				5
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