Activities in Sub Family	Endo-β-1,4-glucanase (EC 3.2.1.4);
Mechanism	Retaining e
Clan	GH-A
3D Structure Status	( β / α ) 8 barrel
Catalytic Nucleophile/Base	Glu (experimental)
Catalytic Proton Donor	Glu (experimental)
Note	Once known as cellulase family A; many members have been assigned to subfamilies as described by Aspeborg et al. (2012) BMC Evol Biol. 12(1):186 (PMID: 22992189).
External resources	CAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)	MEGAZYME; NZYTech; PROZOMIX;
Statistics	GenBank accession (2130); Uniprot accession (61); PDB accession (35); 3D entries (9); cryst (0)

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Eukaryota
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D	Subf
563796		Cadophora sp. DSE1049 v1 (Cadsp1)				5
614602		Cadophora sp. DSE1049 v1 (Cadsp1)				5
659706		Cadophora sp. DSE1049 v1 (Cadsp1)				5
574545		Cadophora sp. DSE1049 v1 (Cadsp1)				5
632545		Cadophora sp. DSE1049 v1 (Cadsp1)				5
10620		Cadophora sp. M221 (CadmalM221_1)				5
6023		Cadophora sp. M221 (CadmalM221_1)				5
16311		Cadophora sp. M221 (CadmalM221_1)				5
13380		Cadophora sp. M221 (CadmalM221_1)				5
14842		Cadophora sp. M221 (CadmalM221_1)				5
10651		Cadophora sp. M221 (CadmalM221_1)				5
8970		Cadophora sp. M221 (CadmalM221_1)				5
523322		Caecomyces churrovis (Caecom1)				5
390596		Caecomyces churrovis (Caecom1)				5
525528		Caecomyces churrovis (Caecom1)				5
467890		Calocera cornea (Calco1)				5
550912		Calocera cornea (Calco1)				5
486189		Calocera viscosa v1 (Calvi1)				5
581081		Calocera viscosa v1 (Calvi1)				5
562763		Calycina marina TRa3180A v1.0 (Calmar1)				5
577381		Calycina marina TRa3180A v1.0 (Calmar1)				5
415490		Calycina marina TRa3180A v1.0 (Calmar1)				5
204163		Calycina marina TRa3180A v1.0 (Calmar1)				5
563874		Calycina marina TRa3180A v1.0 (Calmar1)				5
647162		Camillea tinctor CBS 203.56 v1.0 (CtCBS203_1)				5
717899		Camillea tinctor CBS 203.56 v1.0 (CtCBS203_1)				5
696533		Camillea tinctor CBS 203.56 v1.0 (CtCBS203_1)				5
344761		Camillea tinctor CBS 203.56 v1.0 (CtCBS203_1)				5
699815		Camillea tinctor CBS 203.56 v1.0 (CtCBS203_1)				5
148462		Thielavia arenaria CBS 508.74 v1 (Thiar1)				5
705187		Thielavia arenaria CBS 508.74 v1 (Thiar1)				5
702070		Thielavia arenaria CBS 508.74 v1 (Thiar1)				5
7857		Capronia coronata CBS 617.96 (Capcor1)				5
700549		Cenococcum geophilum 1.58 v2.0 (Cenge3)				5
693399		Cenococcum geophilum 1.58 v2.0 (Cenge3)				5
RhiJN_09269		Ceratobasidium sp. AG-Ba JN	QRV81254.1			5
RhiJN_09250		Ceratobasidium sp. AG-Ba JN	QRV81235.1			5
RhiJN_10663		Ceratobasidium sp. AG-Ba JN	QRV82648.1			5
RhiJN_27276		Ceratobasidium sp. AG-Ba JN	QRV99257.1			5
RhiJN_23728		Ceratobasidium sp. AG-Ba JN	QRV95710.1			5
RhiJN_23727		Ceratobasidium sp. AG-Ba JN	QRV95709.1			5
RhiJN_06782		Ceratobasidium sp. AG-Ba JN	QRV78767.1			5
RhiJN_24670		Ceratobasidium sp. AG-Ba JN	QRV96652.1			5
RhiJN_21564		Ceratobasidium sp. AG-Ba JN	QRV93546.1			5
RhiJN_13169		Ceratobasidium sp. AG-Ba JN	QRV85151.1			5
RhiJN_09249		Ceratobasidium sp. AG-Ba JN	QRV81234.1			5
RhiJN_23744		Ceratobasidium sp. AG-Ba JN	QRV95726.1			5
RhiLY_06698		Ceratobasidium sp. AG-Ba LY	QRW07699.1			5
RhiLY_12755		Ceratobasidium sp. AG-Ba LY	QRW13756.1			5
RhiLY_09030		Ceratobasidium sp. AG-Ba LY	QRW10031.1			5
RhiLY_09008		Ceratobasidium sp. AG-Ba LY	QRW10009.1			5
RhiLY_10402		Ceratobasidium sp. AG-Ba LY	QRW11403.1			5
RhiLY_09007		Ceratobasidium sp. AG-Ba LY	QRW10008.1			5
454970		Cercophora caudata CBS 606.72 v1.0 (Cercau1)				5
571752		Cercophora caudata CBS 606.72 v1.0 (Cercau1)				5
570901		Cercophora caudata CBS 606.72 v1.0 (Cercau1)				5
427005		Cercophora newfieldiana SMH2532-1 (Cernew1)				5
408335		Cercophora newfieldiana SMH2532-1 (Cernew1)				5
427918		Cercophora newfieldiana SMH2532-1 (Cernew1)				5
319227		Cercophora newfieldiana SMH2532-1 (Cernew1)				5
507798		Cercophora newfieldiana SMH2532-1 (Cernew1)				5
101752		Cercophora scortea SMH4131-1 v1.0 (Cersc1)				5
185153		Cercophora scortea SMH4131-1 v1.0 (Cersc1)				5
445402		Cercophora scortea SMH4131-1 v1.0 (Cersc1)				5
362978		Cercophora scortea SMH4131-1 v1.0 (Cersc1)				5
20235		Cercophora scortea SMH4131-1 v1.0 (Cersc1)				5
CBHEV_LOCUS10798		Cercospora beticola	CAK1365210.1			5
CBHEV_LOCUS4178		Cercospora beticola	CAK1358352.1			5
79557		Ceriporiopsis (Gelatoporia) subvermispora B (Cersu1)				5
117046		Ceriporiopsis (Gelatoporia) subvermispora B (Cersu1)				5
337715		Chaetomidium fimeti CBS168.71 (Chafi1)				5
21650		Chaetomidium fimeti CBS168.71 (Chafi1)				5
124051		Chaetomidium fimeti CBS168.71 (Chafi1)				5
18441		Chaetomidium leptoderma CBS 538.74 v1.0 (Chale1)				5
40923		Chaetomidium leptoderma CBS 538.74 v1.0 (Chale1)				5
40405		Chaetomidium leptoderma CBS 538.74 v1.0 (Chale1)				5
30119		Chaetomium funicola CBS 141.50 v1.0 (Chafun1)				5
27352		Chaetomium funicola CBS 141.50 v1.0 (Chafun1)				5
36044		Chaetomium funicola CBS 141.50 v1.0 (Chafun1)				5
364486		Chaetomium (Dichotomopilus) funicola MPI-SDFR-AT-0129 v1.0 (Chafu1)				5
244234		Chaetomium (Dichotomopilus) funicola MPI-SDFR-AT-0129 v1.0 (Chafu1)				5
452039		Chaetomium (Dichotomopilus) funicola MPI-SDFR-AT-0129 v1.0 (Chafu1)				5
43929		Chaetomium globosum MPI-SDFR-AT-0079 v1.0 (Chagl1)				5
547268		Chaetomium globosum MPI-SDFR-AT-0079 v1.0 (Chagl1)				5
562269		Chaetomium globosum MPI-SDFR-AT-0079 v1.0 (Chagl1)				5
344946		Chaetomium sp. MPI-CAGE-AT-0009 v1.0 (Chame1)				5
308227		Chaetomium sp. MPI-CAGE-AT-0009 v1.0 (Chame1)				5
22114		Chaetomium sp. MPI-CAGE-AT-0009 v1.0 (Chame1)				5
6869		Chaetomium thermophilum var thermophilum DSM 1495 (Chathe1)				5
6845		Chaetomium thermophilum var thermophilum DSM 1495 (Chathe1)				5
639		Chaetomium thermophilum var thermophilum DSM 1495 (Chathe1)				5
2872		Chaetomium thermophilum var thermophilum DSM 1495 (Chathe1)				5
403283		Chalara longipes (Chalo1)				5
557819		Chalara longipes (Chalo1)				5
400772		Chalara longipes (Chalo1)				5
547651		Chalara longipes (Chalo1)				5
331342		Chalara longipes (Chalo1)				5
493206		Chalara longipes (Chalo1)				5
493000		Chalara longipes (Chalo1)				5
503092		Chalara longipes (Chalo1)				5
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