Activities in Sub Family	Chitosanase (EC 3.2.1.132); Endo-β-1,4-glucanase (EC 3.2.1.4); Lichenase / endo-β-1,3-1,4-glucanase (EC 3.2.1.73); Endo-β-1,4-xylanase (EC 3.2.1.8);
Mechanism	Retaining e
Clan	GH-A
3D Structure Status	( β / α ) 8 barrel
Catalytic Nucleophile/Base	Glu (experimental)
Catalytic Proton Donor	Glu (experimental)
Note	Once known as cellulase family A; many members have been assigned to subfamilies as described by Aspeborg et al. (2012) BMC Evol Biol. 12(1):186 (PMID: 22992189).
External resources	CAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)	MEGAZYME; NZYTech; PROZOMIX;
Statistics	GenBank accession (10); Uniprot accession (147); PDB accession (47); 3D entries (17); cryst (0)

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Bacteria
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D	Subf
HXZ27_12705		Micromonospora carbonacea aurantiaca	QLD24965.1			2
PVK37_24810		Micromonospora sp. HUAS 3	WDZ83658.1			2
PVK37_23505		Micromonospora sp. HUAS 3	WDZ83405.1			2
GA0070614_0094		Micromonospora coxensis DSM 45161	SCG34747.1			2
ID554_26720		Micromonospora craniellae LHW63014	QOC91518.1			2
ID554_29905		Micromonospora craniellae LHW63014	QOC92029.1			2
GA0070610_3306		Micromonospora echinofusca DSM 43913	SCG17005.1			2
GA0070618_5067		Micromonospora echinospora DSM 43816	SCF30627.1			2
GA0070618_5917		Micromonospora echinospora DSM 43816	SCF37480.1			2
Jiend_55460		Micromonospora endophytica NBRC 109090	BCJ62124.1			2
Jiend_02220		Micromonospora endophytica NBRC 109090	BCJ56800.1			2
VAB18032_24085		Micromonospora maris AB-18-032	AEB45915.1			2
GA0070621_1393		Micromonospora narathiwatensis DSM 45248	SBT42013.1			2
Q3V37_23760		Micromonospora profundi TRM95458	WLS44381.1			2
GA0074696_3702		Micromonospora purpureochromogenes DSM 43821	SCF24260.1			2
GA0070623_0785		Micromonospora rifamycinica DSM 44983	SCG41432.1			2
GCM10017556_57370		Micromonospora sagamiensis JCM 3310	BCL17998.1			2
GCM10017556_51460		Micromonospora sagamiensis JCM 3310	BCL17407.1			2
GA0074704_3372		Micromonospora siamensis DSM 45097	SCG57304.1			2
MicB006_6096		Micromonospora sp. B006	AXO38354.1			2
FJK98_17945		Micromonospora sp. HM134	QDY08796.1			2
ML5_5408		Micromonospora sp. L5	ADU10877.1			2
PCA76_18885		Micromonospora sp. LH3U1	WCN79086.1			2
O7604_24895		Micromonospora sp. WMMA1947	WBC12300.1			2
O7546_13330		Micromonospora sp. WMMA1976	WBC06415.1			2
O7600_02595		Micromonospora sp. WMMA1998	WBC17956.1			2
CO540_05510		Micromonospora sp. WMMA2032	ATO13355.1			2
O7542_11230		Micromonospora sp. WMMC264	WBB88362.1			2
GKC29_15740		Micromonospora sp. WMMC415	QGN48149.1			2
O7622_18605		Micromonospora sp. WMMD1076	WFF05069.1			2
O7602_14805		Micromonospora sp. WMMD1128	WBB76723.1			2
O7602_11005		Micromonospora sp. WMMD1128	WBB76005.1			2
O7617_26880 (fragment)		Micromonospora sp. WMMD1155	WFE53734.1			2
O7633_32975		Micromonospora sp. WMMD712	WFE61790.1			2
O7625_22220		Micromonospora sp. WMMD714	WFE65828.1			2
O7606_04320		Micromonospora sp. WMMD882	WBB80623.1			2
O7616_23010		Micromonospora sp. WMMD964	WFE99741.1			2
O7613_08965		Micromonospora sp. WMMD975	WFE36652.1			2
O7613_12750		Micromonospora sp. WMMD975	WFE36211.1			2
O7612_15640		Micromonospora sp. WMMD987	WFE92861.1			2
O7619_17765		Micromonospora sp. WMMD998	WFE40187.1			2
CSH63_10190		Micromonospora tulbaghiae CNY-010	AYF27799.1			2
GA0070619_3022		Micromonospora zamorensis DSM 45600	SCG53995.1			2
A7982_04389		Minicystis rosea DSM 24000	APR79042.1			2
RZE84_08200		Mollicutes bacterium LVI A0075	WOO88889.1			2
R2F61_08425		Mollicutes bacterium LVI A0078	WOO90735.1			2
HYN43_016955		Mucilaginibacter celer HYN0043	AYL96888.1			2
SAMN05216490_0949		Mucilaginibacter mallensis MP1X4	SDS32391.1			2
HH214_07765		Mucilaginibacter robiniae F39-2	QJD95774.1			2
DEO27_000905		Mucilaginibacter rubeus P1	QEM08634.1			2
GWR56_11985		Mucilaginibacter sp. 14171R-50	QHS56219.1			2
A0256_21225		Mucilaginibacter sp. PAMC 26640	AMR33776.1			2
MTO98_06865		Mucilaginibacter sp. SMC90	UOE50797.1			2
Dd703_1886		Musicola paradisiaca Ech703	ACS85678.1			2
LV483_07275 (fragment)		Myxococcales bacterium MSr11368	WXA86079.1			2
Niako_3530		Niastella koreensis GR20-10	AEV99831.1			2
Niako_4179		Niastella koreensis GR20-10	AEW00453.1			2
KGD83_19025		Nocardiopsis akebiae HDS12	QUX27399.1			2
B005_3970		Nocardiopsis alba ATCC BAA-2165	AFR08794.1			2
KGD84_21825		Nocardiopsis changdeensis Mg02	QUX21074.1			2
CGQ36_10255		Nocardiopsis dassonvillei HZNU_N_1	ASU57907.1			2
NCTC10488_00036 (CelE)		Nocardiopsis dassonvillei NCTC10488	VEI86457.1			2
A9R04_10425		Nocardiopsis dassonvillei NOCA502F	APC35073.1			2
Ndas_1368		Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111	ADH66800.1			2
NE857_12690		Nocardiopsis exhalans JCM11759T	USY22386.1			2
PV789_11180		Nocardiopsis sp. DZFXJ 01	WDZ93053.1			2
K1J57_31280		Nocardiopsis sp. MT53	QYX37004.1			2
Nocox_28680 (CelE)		Nonomuraea coxensis DSM 45129	QYC43320.1			2
BN4615_P6407		Nonomuraea gerenzanensis ATCC 39727	SBO96891.1			2
LCN96_29570		Nonomuraea gerenzanensis L70	UBU08542.1			2
WBK31_10960		Nonomuraea sp. N2-4H	WXK66990.1			2
DZC78_00765		Olleya aquimaris DAU311	AXO78975.1			2
CW732_04295		Olleya sp. Bg11-27	AUC74935.1			2
H0I26_04190		Olleya sp. HaHaR_3_96	QXP60845.1			2
AR543_07145 (fragment)		Paenibacillus bovis BD3526	ANF95802.1			2
cellulase (fragment)		Paenibacillus campinasensis BL11	ADI39639.1			2
endo-β-1,4-glucanase, partial (CelD) (fragment)		Paenibacillus campinasensis NZ-2	QEQ43011.1			2
B9T62_05285		Paenibacillus donghaensis KCTC 13049	ASA20263.1			2
SK066_19205 (fragment)		Paenibacillus hunanensis Y9	WPP40704.1			2
B4V02_06945		Paenibacillus kribbensis AM49	ASR46431.1			2
PQ456_04435		Paenibacillus kyungheensis KACC 18744	WCT56778.1			2
endo-β-1,4-glucanase 3a (possible fragment)		Paenibacillus lautus	CAA01935.1			2
PM3016_5775		Paenibacillus mucilaginosus 3016	AFC32453.1			2
B2K_29390		Paenibacillus mucilaginosus K02	AFH64766.1 AFK65318.1			2
ERY13_28690		Paenibacillus mucilaginosus KN-18	WFA20936.1			2
KNP414_06148		Paenibacillus mucilaginosus KNP414	AEI44672.1			2
KCX80_27895		Paenibacillus mucilaginosus PM12	WDM26231.1			2
AASFL403_14880		Paenibacillus nuruki AASFL403	CAJ1316506.1			2
ABE82_18615		Paenibacillus peoriae HS311	ALA43398.1			2
RBB83_19845		Paenibacillus peoriae JJ21	WVX09690.1			2
MLD56_18720		Paenibacillus peoriae ZBSF16	UMY53591.1			2
IAQ67_21200		Paenibacillus peoriae ZF390	QNR66332.1			2
G7L40_15260		Paenibacillus polymyxa 2020	QPK59000.1			2
G7L40_22960		Paenibacillus polymyxa 2020	QPK60378.1			2
QNH38_12095		Paenibacillus polymyxa ACCC03434	WHX38149.1			2
QNH38_18715		Paenibacillus polymyxa ACCC03434	WHX34603.1			2
VK72_19185		Paenibacillus polymyxa ATCC 15970	APQ60687.1			2
CUU60_09535		Paenibacillus polymyxa ATCC 842	UOD85444.1			2
CUU60_01895		Paenibacillus polymyxa ATCC 842	UOD84008.1			2
CPY53_01005		Paenibacillus polymyxa C12	UNL92224.1			2
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