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Glycoside Hydrolase Family 5 / Subf 2

Activities in Sub FamilyChitosanase (EC 3.2.1.132);
Endo-β-1,4-glucanase (EC 3.2.1.4);
Lichenase / endo-β-1,3-1,4-glucanase (EC 3.2.1.73);
Endo-β-1,4-xylanase (EC 3.2.1.8);
Mechanism Retaining e
ClanGH-A
3D Structure Status( β / α ) 8 barrel
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental)
NoteOnce known as cellulase family A; many members have been assigned to subfamilies as described by Aspeborg et al. (2012) BMC Evol Biol. 12(1):186 (PMID: 22992189).
External resourcesCAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; NZYTech; PROZOMIX;
Statistics GenBank accession (10); Uniprot accession (147); PDB accession (47); 3D entries (17); cryst (0)
Summary
Download GH5_2 (2298) Taxonomic display Structure (17) Characterized (129)
| 1 | ... | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 | 21 |
Bacteria
Protein Name EC#Organism GenBankUniprotPDB/3DSubf
 endo-β-1,4-glucanase / celulase (CelDZ1a) 3.2.1.4 Thermoanaerobacterium sp. A57Txylan ALX38276.1 A0A0U4EBH5
I3VS73		 5FIP[A,B,C,D] 2
 PGH24_02860   Thermoanaerobacterium thermosaccharolyticum MJ1 WHE07709.1     2
 endo-1,4-beta glucanase E5   Thermobifida alba AHK119 BBA57842.1     2
 FOF52_01235   Thermobifida alba DSM 43795 UPT19757.1     2
 IM867_08850   Thermobifida fusca UPMC 901 QOS57567.1     2
 endo-β-1,4-glucanase 5A (E5;CelE;TfCel5A;Tfu_0901) (Cel5A) 3.2.1.4 Thermobifida fusca YX AAZ54939.1
AAC09379.1		 Q01786
Q47RH8		 2CKR[A,B]
2CKS[A,B] 		2
 NI17_001845   Thermobifida halotolerans DSM 44931 UOE20021.1     2
 cellulase / endo-β-1,4-glucanase (ThCel5) (Cel5A) 3.2.1.4 Thermobifida halotolerans YIM 90462 AFK65733.1     2
 DYE50_07215   Treponema ruminis RU1 QSI02355.1     2
 TRSA_13910   Treponema saccharophilum JCM 32279 BDC96292.1     2
 TRSA_04200   Treponema saccharophilum JCM 32279 BDC95321.1     2
 P0M28_12990   Tunicatimonas pelagia NBRC 107804 WKN45875.1     2
 endo-1,4-β-glucanase, partial (Cel5A) (fragment)   uncultured Bacillus sp. AKP92783.1     2
 ORF (fragment)   uncultured bacterium CAR66437.1     2
 ORF (fragment)   uncultured bacterium CAR66438.1     2
 glycoside hydrolase   uncultured bacterium AMO13171.1     2
 cellulase 5R (Cel5R;Cel5R_FS) 3.2.1.4 uncultured bacterium AND74761.1 A0A172PZJ4 5I2U[A,B] 2
 ORF (fragment)   uncultured bacterium ACN90881.1     2
 ORF (fragment)   uncultured bacterium ACN90882.1     2
 ORF (fragment)   uncultured bacterium ACN90883.1     2
 ORF (fragment)   uncultured bacterium ACN90884.1     2
 ORF (fragment)   uncultured bacterium ACN90885.1     2
 ORF (fragment)   uncultured bacterium ACN90886.1     2
 ORF (fragment)   uncultured bacterium ACN90888.1     2
 ORF (fragment)   uncultured bacterium ACN90889.1     2
 ORF (fragment)   uncultured bacterium ACN90890.1     2
 ORF (fragment)   uncultured bacterium ACN90891.1     2
 IL_H1_CDS_27   uncultured bacterium SIP56560.1     2
 IL_B3_CDS_15   uncultured bacterium SIP56505.1     2
 Endoglucanase A precursor   uncultured bacterium SIP56455.1     2
 IL_C5_CDS_1   uncultured bacterium SIP56247.1     2
 bifunctional beta 1,4-endoglucanase/cellobiohydrolase, partial (CelaB) (fragment)   uncultured bacterium ARD05451.1     2
 bifunctional beta 1,4-endoglucanase/cellobiohydrolase, partial (CelaB) (fragment)   uncultured bacterium ARD05450.1     2
 bifunctional beta 1,4-endoglucanase/cellobiohydrolase, partial (CelaB) (fragment)   uncultured bacterium ARD05452.1     2
 pcel4818Cel5_2A (fragment)   uncultured bacterium QBR94633.1     2
 cellulase, partial (fragment)   uncultured bacterium QHD57707.1     2
 Cel4   uncultured bacterium QJT73064.1     2
 BGL1   uncultured bacterium QJT73069.1     2
 CelXyn1   uncultured bacterium QJT73075.1     2
 cellulase (CelA3;BP-CelA3) (fragment) 3.2.1.4 uncultured bacterium AEW10554.1 H2BNN7   2
 cellulase (CelA84;EF-84D8)   uncultured bacterium AEW10555.1     2
 YBcontig212-01191-9   uncultured bacterium ADU86904.1     2
 cold-active cellulase   uncultured bacterium QSV39134.1     2
 β-glucanase (UmCel5G;RC1) 3.2.1.4 uncultured bacterium ABA42184.1 Q3HXC4   2
 β-glucanase (UmCel5H;RC2) 3.2.1.4 uncultured bacterium ABA42185.1 Q3HXC3   2
 endo-1,4-β-glucanase, partial   uncultured bacterium QZL11395.1     2
 endo-β-1,4-glucanase (CRS200) (Cel5B) 3.2.1.4 uncultured bacterium AFJ44728.1 I2B2S2   2
 cold active cellulase, partial   uncultured bacterium UGO92605.1     2
 endo-β-1,4-glucanase (CelWS15)   uncultured bacterium AFX88669.1     2
 endo-β-1,4-glucanase (CelWS3) 3.2.1.4 uncultured bacterium AFX88673.1 M4I2I3   2
 endo-β-1,4-glucanase (CelWS14) 3.2.1.4 uncultured bacterium AFX88668.1 M4I2I2   2
 endo-β-1,4-glucanase (CelWS6) 3.2.1.4 uncultured bacterium AFX88666.1 M4I2R3   2
 endo-β-1,4-glucanase (CelWS36) 3.2.1.4 uncultured bacterium AFX88672.1 M4I2J6   2
 endo-β-1,4-glucanase (CelWS7) 3.2.1.4 uncultured bacterium AFX88667.1 M4I2J5   2
 endo-β-1,4-glucanase (CelWS20)   uncultured bacterium AFX88670.1     2
 cellulase (CS10;CelCS10) 3.2.1.4 uncultured bacterium AGL50932.1 R4P2Q6   2
 endo-β-1,4-glucanase (RC3) 3.2.1.4 uncultured bacterium ABI94085.1 Q06B38   2
 endo-β-1,4-glucanase (RC5) 3.2.1.4 uncultured bacterium ABI94086.1 Q06B37   2
 GH5_2   uncultured bacterium CAK9709221.1     2
 GH5_2   uncultured bacterium CAK9710335.1     2
 endo-β-1,4-glucanase (Endos11)   uncultured bacterium AGW99967.1     2
 endo-β-1,4-glucanase (Endos9)   uncultured bacterium AGW99965.1     2
 endo-β-1,4-glucanase (Endos3)   uncultured bacterium AGW99959.1     2
 endo-β-1,4-glucanase (Endos15)   uncultured bacterium AGW99971.1     2
 endo-β-1,4-glucanase (Endos1)   uncultured bacterium AGW99957.1     2
 endo-β-1,4-glucanase (Endos19)   uncultured bacterium AGW99975.1     2
 endo-β-1,4-glucanase (Endos13)   uncultured bacterium AGW99969.1     2
 endo-β-1,4-glucanase (Endos7)   uncultured bacterium AGW99963.1     2
 endo-β-1,4-glucanase (Endos4)   uncultured bacterium AGW99960.1     2
 endo-β-1,4-glucanase (Endos10)   uncultured bacterium AGW99966.1     2
 endo-β-1,4-glucanase (Endos18)   uncultured bacterium AGW99974.1     2
 endo-β-1,4-glucanase (Endos2)   uncultured bacterium AGW99958.1     2
 endo-β-1,4-glucanase (Endos20)   uncultured bacterium AGW99976.1     2
 endo-β-1,4-glucanase (Endos8)   uncultured bacterium AGW99964.1     2
 endo-β-1,4-glucanase (Endos16)   uncultured bacterium AGW99972.1     2
 endo-β-1,4-glucanase (Endos6)   uncultured bacterium AGW99962.1     2
 endo-β-1,4-glucanase (Endos12)   uncultured bacterium AGW99968.1     2
 endo-β-1,4-glucanase (Endos5)   uncultured bacterium AGW99961.1     2
 endo-β-1,4-glucanase (Endos14)   uncultured bacterium AGW99970.1     2
 endo-β-1,4-glucanase (Endos17)   uncultured bacterium AGW99973.1     2
 cellulase (CelE1) 3.2.1.4 uncultured bacterium AHA42547.2
AHA42547.1		 A0A0R5P8X1
V5KYY9		 4M1R[A,B] 2
 cellulase (C1A1) 3.2.1.4 uncultured bacterium BAO65790.1     2
 endoglucanase (C1A2) 3.2.1.4 uncultured bacterium BAO65795.1     2
 cellulase (C2A3) 3.2.1.4 uncultured bacterium BAO65801.1     2
 4348GL29_002   uncultured bacterium ABW39336.1     2
 4348GL29_006   uncultured bacterium ABW39337.1     2
 4348JG21_002   uncultured bacterium ABW39342.1     2
 4348JG42_001   uncultured bacterium ABW39350.1     2
 4399GL23_006   uncultured bacterium ABW39355.1     2
 4399GL43_001   uncultured bacterium ABW39356.1     2
 4399GL44_001   uncultured bacterium ABW39357.1     2
 4399GL47_001   uncultured bacterium ABW39358.1     2
 ORF   uncultured bacterium Ad_113_F04_contig2 AIF25991.1     2
 ORF   uncultured bacterium Ad_125_D08 AIF26053.1     2
 ORF   uncultured bacterium Ad_143_A19 AIF26140.1     2
 ORF   uncultured bacterium Ad_143_D13_contig1 AIF26172.1     2
 ORF   uncultured bacterium Ad_144_C12_contig2 AIF26213.1     2
 ORF (fragment)   uncultured bacterium Ad_150_H18 AIF26216.1     2
 endoglucanase Z precursor (endo-1,4-β-glucanase Z) (cellulase Z) (EGZ)   uncultured bacterium contig00103 AGS52465.1     2
 glycoside hydrolase family 5   uncultured bacterium contig00118 AGS51869.1     2
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