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Glycoside Hydrolase Family 5 / Subf 2

Activities in Sub FamilyChitosanase (EC 3.2.1.132);
Endo-β-1,4-glucanase (EC 3.2.1.4);
Lichenase / endo-β-1,3-1,4-glucanase (EC 3.2.1.73);
Endo-β-1,4-xylanase (EC 3.2.1.8);
Mechanism Retaining e
ClanGH-A
3D Structure Status( β / α ) 8 barrel
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental)
NoteOnce known as cellulase family A; many members have been assigned to subfamilies as described by Aspeborg et al. (2012) BMC Evol Biol. 12(1):186 (PMID: 22992189).
External resourcesCAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; NZYTech; PROZOMIX;
Statistics GenBank accession (10); Uniprot accession (147); PDB accession (47); 3D entries (17); cryst (0)
Summary
Download GH5_2 (2298) Taxonomic display Structure (17) Characterized (129)
| 1 | ... | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 | ... | 21 |
Bacteria
Protein Name EC#Organism GenBankUniprotPDB/3DSubf
 C6W10_11910   Plantactinospora sp. BB1 AVT37049.1     2
 C6361_13510   Plantactinospora sp. BC1 AVT30345.1     2
 CIK06_15180   Plantactinospora sp. KBS50 ASW55230.1     2
 JL193_04210   Polaribacter batillariae G4M1 QTD38500.1     2
 JL193_04165   Polaribacter batillariae G4M1 QTD38491.1     2
 H9I45_05895   Polaribacter haliotis KCTC 52418 QOD61974.1     2
 BTO07_06690   Polaribacter sp. SA4-12 ARV14855.1     2
 E8A73_004265   Polyangium aurulentum SDU3-1 UQA63524.1     2
 Prubr_38470   Polymorphospora rubra NBRC 101157 BCJ66826.1     2
 RJD25_22010   Pontibacter sp. G13 WNJ17533.1     2
 RJD25_06990   Pontibacter sp. G13 WNJ20209.1     2
 C1N53_16505   Pontibacter sp. SGAir0037 QCR23793.1     2
 prwr041_03620   Prevotella herbatica WR041 BCS84469.1     2
 endoglucanase   Priestia aryabhattai JGLY-1 WDV57395.1     2
 endo-glucanase   Priestia megaterium AP25 ADI82821.1     2
 endo-β-1,4-glucanase   Priestia megaterium IARI-SP-9 AGW99981.1     2
 glucanase (BglC) 3.2.1.4 Priestia megaterium L103 AGG91154.1 V5JAY7   2
 Ser39006_2780   Prodigiosinella confusarubida ATCC 39006 AGU87995.1
AUH00725.1
AUH05046.1		     2
 GCM10025730_14930   Promicromonospora thailandica JCM 17130 BFF17972.1     2
 PARC_b0695   Pseudoalteromonas arctica A 37-1-2 ATC88864.1     2
 Patl_1404   Pseudoalteromonas atlantica T6c ABG39929.1     2
 PCAR9_B0611 (fragment)   Pseudoalteromonas carrageenovora IAM 12662 ATCC 43555 SOU43078.1     2
 PCAR9_B0610 (fragment)   Pseudoalteromonas carrageenovora IAM 12662 ATCC 43555 SOU43077.1     2
 PC2016_3299 (fragment)   Pseudoalteromonas carrageenovora KCTC 22325 QBJ73479.1     2
 FFU37_16790   Pseudoalteromonas distincta 16-SW-7 QCU76129.1     2
 CelA8   Pseudoalteromonas haloplanktis ADI47126.1     2
 endoglucanase (CelG) (Cel5G) 3.2.1.4 Pseudoalteromonas haloplanktis A23 CAA76775.1 O86099 1TVN[A,B]
1TVP[A,B] 		2
 endoglucanase (Cel5A)   Pseudoalteromonas haloplanktis A5 ADD17064.1     2
 S4054_20400   Pseudoalteromonas luteoviolacea S4054 AOT19860.1     2
 S40542_20395   Pseudoalteromonas luteoviolacea S40542 AOT14944.1     2
 S4054249_20425   Pseudoalteromonas luteoviolacea S4054249 AOT10033.1     2
 CWC22_022555   Pseudoalteromonas rubra S4059 QPB85787.1     2
 AT705_23635   Pseudoalteromonas rubra SCSIO 6842 ALU45920.1     2
 AOR04_20710   Pseudoalteromonas sp. 1_2015MBL_MicDiv ATG79951.1     2
 PA25_37890   Pseudoalteromonas sp. A25 BBN83804.1     2
 D172_019580   Pseudoalteromonas sp. Bsw20308 ALQ10273.1
AEK35325.1		     2
 RB214_19650   Pseudoalteromonas sp. HL-AS1 WMS92681.1     2
 JG479_17320   Pseudoalteromonas sp. LC2018020214 QQM66350.1     2
 endoglucanase (CelA) 3.2.1.4 Pseudoalteromonas sp. MB-1 AAS58467.1 Q6QA02   2
 cellulase (CelY) 3.2.1.4 Pseudoalteromonas sp. NO3 ACN62172.1 C0KZC4   2
 ELR70_03455   Pseudoalteromonas sp. R3 AZZ96267.1     2
 J8Z24_12425   Pseudoalteromonas sp. SCSIO 43201 USD27741.1     2
 J5X90_23120   Pseudoalteromonas viridis BBR56 QTL37730.1     2
 FSB84_20490   Pseudobacter ginsenosidimutans Gsoil 221 QEC43940.1     2
 FSB84_22545   Pseudobacter ginsenosidimutans Gsoil 221 QEC44320.1     2
 cellulase (AclA) 3.2.1.4 Pseudomonas sp. ND137 BAB79288.1 Q8VUT3   2
 endo-β-1,4-glucanase (CelX) 3.2.1.4 psychrophilic marine bacterium DY3 AAP04424.1 Q841J5   2
 E9099_17595   Psychroserpens sp. NJDZ02 QCE43156.1     2
 FN924_16515   Radiobacillus deserti TKL69 QDP42240.1     2
 KO561_17250   Radiobacillus kanasensis 80 UFT98918.1     2
 HF520_08270   Romboutsia sp. CE17 QJA08944.1     2
 N4261_12980   Roseateles amylovorans BIM B-1768 UXH80730.1     2
 RD2015_3542   Roseateles depolymerans KCTC 42856 ALV07998.1     2
 OU995_12805   Roseateles sp. SL47 WAC75522.1     2
 DC20_12305   Rufibacter tibetensis 1351 ALJ01419.1     2
 DC20_05235   Rufibacter tibetensis 1351 ALJ01230.1     2
 DC20_16535   Rufibacter tibetensis 1351 ALJ01521.1     2
 β-1,4-glucanase 5I (Cel5I; Ccel_0428) (Cel5I) 3.2.1.4 Ruminiclostridium cellulolyticum H10 ACL74811.1
AAL79562.1		 B8I5Z4
Q8RLT7		   2
 endo-β-1,4-glucanase 5A (CelA) (Cel5A) 3.2.1.4 Ruminiclostridium josui BAA12826.1
BAA12826.2		 Q59290   2
 P0092_07245   Ruminiclostridium papyrosolvens DSM 2782 WES35754.1     2
 cellulase 5A (Cel5A)   Ruminococcus albus QPB75699.1     2
 cellulase 5A (Cel5A)   Ruminococcus albus QPB75691.1     2
 cellulase 5A, partial (Cel5A) (fragment)   Ruminococcus albus QPB75696.1     2
 cellulase 5A (Cel5A)   Ruminococcus albus QPB75689.1     2
 cellulase 5A (Cel5A)   Ruminococcus albus QPB75693.1     2
 endo-1,4-glucanase 4 (EGIV) 3.2.1.4 Ruminococcus albus BAA32286.1 Q07940   2
 Rumal_1845   Ruminococcus albus 7 = DSM 20455 ADU22343.1     2
 RBI_I00026   Ruminococcus bicirculans (ex Wegman et al. 2014) 80/3 CCO03766.1     2
 DTQ70_27660   Runella sp. SP2 AYQ35713.1     2
 FFV09_20295   Saccharibacillus brassicae ATSA2 QDH22988.1     2
 endo-β-1,4-glucanase 5J (Sde_2494) (processive) (Cel5J) 3.2.1.4 Saccharophagus degradans 2-40 ABD81754.1 Q21HS5   2
 endoglucanase 5A (Sde_3003) (Cel5A) 3.2.1.4 Saccharophagus degradans 2-40 ABD82260.1 Q21GB9   2
 endoglucanase 5A (Sde_3003) (Cel5A)   Saccharophagus degradans 2-40 ABD82260.1 Q21GB9   2
 endo-β-1,4-glucanase 5H (Sde_3237) (processive) (Cel5H) 3.2.1.4 Saccharophagus degradans 2-40 ABD82494.1 Q21FN5   2
 endo-β-1,4-glucanase 5G (Sde_3239) (processive) (Cel5G) 3.2.1.4 Saccharophagus degradans 2-40 ABD82496.1 Q21FN3   2
 QFX18_04460   Saccharophagus degradans FZY0027 WGO99311.1     2
 QFX18_04450   Saccharophagus degradans FZY0027 WGO99309.1     2
 QFX18_08225   Saccharophagus degradans FZY0027 WGP00035.1     2
 QFX18_05655 (fragment)   Saccharophagus degradans FZY0027 WGO99546.1     2
 endoglucanase (Egl-R1)   Saccharophagus sp. JAM-R001 BAI50016.1     2
 cellulase (CelMytA)   Saccharophagus sp. Myt-1 BAL42331.1     2
 cellulase (CelMytA)   Saccharophagus sp. Myt-1 BAL42331.1     2
 cellulase (CelMytB) 3.2.1.4 Saccharophagus sp. Myt-1 BAM21527.1 I4DUD7   2
 JQX30_20355   Saccharopolyspora erythraea NRRL 23338 QRK87195.1     2
 SACE_4004   Saccharopolyspora erythraea NRRL 2338 CAM03275.1     2
 HUO13_18920   Saccharopolyspora erythraea SCSIO 07745 QUH02597.1     2
 J7S33_01880   Saccharothrix algeriensis NRRL B-24137 QTR03816.1     2
 BN6_31760 (CelE)   Saccharothrix espanaensis DSM 44229 type strain: DSM 44229 CCH30481.1     2
 GCM10017745_29650   Saccharothrix mutabilis subsp. capreolus JCM 4248 BFE49538.1     2
 GCM10017745_58870   Saccharothrix mutabilis subsp. capreolus JCM 4248 BFE52460.1     2
 GCM10017745_64360   Saccharothrix mutabilis subsp. capreolus JCM 4248 BFE53009.1     2
 IOD16_25725   Saccharothrix sp. 6-C QQQ80802.1     2
 IOD16_12515   Saccharothrix sp. 6-C QQQ79177.1     2
 L3Q67_36825   Saccharothrix sp. AJ9571 UJW30721.1     2
 EKG83_18505   Saccharothrix syringae NRRL B-16468 QFZ19170.1     2
 EKG83_36265 (fragment)   Saccharothrix syringae NRRL B-16468 QFZ24723.1     2
 Sare_2410   Salinispora arenicola CNS-205 ABV98267.1     2
 Strop_2285   Salinispora tropica CNB-440 ABP54735.1     2
 Strop_4424   Salinispora tropica CNB-440 ABP56852.1     2
 endo-β-1,4-glucanase 5A (Cel5A) 3.2.1.4 Salipaludibacillus agaradhaerens AAC19169.1 O85465 1A3H[A]
1E5J[A]
1H11[A]
1H2J[A]
1H5V[A]
1HF5[A]
1HF6[A]
1HF7[A]
1OCQ[A]
1QHZ[A]
1QI0[A]
1QI2[A]
1W3K[A]
1W3L[A]
2A3H[A]
2V38[A]
3A3H[A]
4A3H[A]
5A3H[A]
6A3H[A]
7A3H[A]
8A3H[A] 		2
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