Glycoside Hydrolase Family 5 / Subf 1

Activities in Familyendo-β-1,4-glucanase / cellulase (EC 3.2.1.4); endo-β-1,4-xylanase (EC 3.2.1.8); β-glucosidase (EC 3.2.1.21); β-mannosidase (EC 3.2.1.25); β-glucosylceramidase (EC 3.2.1.45); glucan β-1,3-glucosidase (EC 3.2.1.58); licheninase (EC 3.2.1.73); exo-β-1,4-glucanase / cellodextrinase (EC 3.2.1.74); glucan endo-1,6-β-glucosidase (EC 3.2.1.75); mannan endo-β-1,4-mannosidase (EC 3.2.1.78); cellulose β-1,4-cellobiosidase (EC 3.2.1.91); steryl β-glucosidase (EC 3.2.1.104); endoglycoceramidase (EC 3.2.1.123); chitosanase (EC 3.2.1.132); β-primeverosidase (EC 3.2.1.149); xyloglucan-specific endo-β-1,4-glucanase (EC 3.2.1.151); endo-β-1,6-galactanase (EC 3.2.1.164); hesperidin 6-O-α-L-rhamnosyl-β-glucosidase (EC 3.2.1.168); β-1,3-mannanase (EC 3.2.1.-); arabinoxylan-specific endo-β-1,4-xylanase (EC 3.2.1.-); mannan transglycosylase (EC 2.4.1.-)
Activities in Sub Family
Mechanism Retaining
ClanGH-A
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental)
NoteOnce known as cellulase family A; many members have been assigned to subfamilies as described by Aspeborg et al. (2012) BMC Evol Biol. 12(1):186 (PMID: 22992189).
External resourcesCAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; NZYTech; PROZOMIX;
Statistics GenBank accession (574); Uniprot accession (102); PDB accession (15); 3D entries (3); cryst (0)
| 1 | 2 | 3 | 4 | 5 |
Bacteria
Protein Name EC#Organism GenBankUniprotPDB/3DSubf
 O77CONTIG1_02914   Leptolyngbya sp. O-77 BAU43092.1     1
 Mahau_1116   Mahella australiensis 50-1 BON AEE96313.1     1
 AZF01_06880   Martelella sp. AD-3 AMM84112.1     1
 CR152_25160   Massilia violaceinigra B2 ATQ77421.1     1
 C6568_02270   Melaminivora sp. SC2-9 AVO48212.1     1
 MEBOL_000684   Melittangium boletus DSM 14713 ATB27246.1     1
 DK389_16305   Methylobacterium sp. 17SD2-17 AWN41780.1     1
 SAMN04489810_3464   Microbacterium pygmaeum DSM 23142 SDH61822.1     1
 BJP65_02895   Microbacterium sp. BH-3-3-3 AOX44867.1     1
 SAMN05216488_1924   Microbacterium sp. LKL04 SCY46623.1     1
 MTES_0141   Microbacterium testaceum StLB037 BAJ73105.1     1
 Mic7113_4470   Microcoleus sp. PCC 7113 AFZ20162.1     1
 Micau_1546   Micromonospora aurantiaca ATCC 27029 ADL45104.1 D9SYR9   1
 GA0070611_6160   Micromonospora auratinigra DSM 44815 SBT53509.1     1
 GA0070612_5967   Micromonospora chokoriensis DSM 45160 SCF29189.1     1
 GA0070607_1055   Micromonospora coriariae DSM 44875 SCE74509.1     1
 GA0070614_4776   Micromonospora coxensis DSM 45161 SCG71042.1     1
 GA0070614_0384   Micromonospora coxensis DSM 45161 SCG37348.1     1
 GA0070610_4046   Micromonospora echinofusca DSM 43913 SCG17725.1     1
 GA0070618_0392   Micromonospora echinospora DSM 43816 SCE71858.1     1
 GA0070621_0342   Micromonospora narathiwatensis DSM 45248 SBT38231.1     1
 GA0070623_2127   Micromonospora rifamycinica DSM 44983 SCG53214.1     1
 GA0074704_2216   Micromonospora siamensis DSM 45097 SCG48664.1     1
 ML5_1807   Micromonospora sp. L5 ADU07338.1 D3C675   1
 CO540_11385   Micromonospora sp. WMMA2032 ATO14339.1     1
 CO540_00195   Micromonospora sp. WMMA2032 ATO12451.1     1
 GA0070619_0769   Micromonospora zamorensis DSM 45600 SCG39192.1     1
 Mflv_3001   Mycolicibacterium gilvum PYR-GCK ABP45478.1 A4TBD9   1
 Mspyr1_23340   Mycolicibacterium gilvum Spyr1 ADT98979.1     1
 Mvan_3505   Mycolicibacterium vanbaalenii PYR-1 ABM14300.1 A1TAV0   1
 BKM31_47890   Nonomuraea sp. ATCC 55076 AQZ68170.1     1
 NIES4070_34790   Nostoc commune HK-02 NIES-4070 BBD67091.1     1
 COO91_04747   Nostoc flagelliforme CCNUN1 AUB38772.1     1
 BZZ01_24965   Nostocales cyanobacterium HT-58-2 ARV61444.1     1
 BZZ01_24160   Nostocales cyanobacterium HT-58-2 ARV61297.1     1
 PBOR_03685   Paenibacillus borealis DSM 13188 AIQ56159.1     1
 B9T62_20790   Paenibacillus donghaensis KCTC 13049 ASA23029.1     1
 PGRAT_15895   Paenibacillus graminis DSM 15220 AIQ68937.1     1
 B4V02_07145   Paenibacillus kribbensis AM49 ASR46467.1     1
 ABE82_18415   Paenibacillus peoriae HS311 ALA43361.1     1
 endo-β-1,4-glucanase 3.2.1.4 Paenibacillus polymyxa AAA22631.1
AAY03292.1
P23548   1
 VK72_18980   Paenibacillus polymyxa ATCC 15970 APQ60649.1     1
 LK13_05715   Paenibacillus polymyxa CF05 AIY08118.1     1
 X809_19500   Paenibacillus polymyxa CR1 AHC21187.1
AIW41095.1
    1
 PPE_03461   Paenibacillus polymyxa E681 ADM71278.1 E0RKS1   1
 C1A50_3796   Paenibacillus polymyxa HY96-2 AUS27960.1     1
 AOU00_05595   Paenibacillus polymyxa J AOK89338.1     1
 PPM_3722 (CelA3)   Paenibacillus polymyxa M1 CCI70531.1     1
 RE92_18740   Paenibacillus polymyxa Sb3-1 AJE52931.1     1
 PPSC2_c3966   Paenibacillus polymyxa SC2 ADO57917.1 E3E5P0   1
 PPSQR21_037080   Paenibacillus polymyxa SQR-21 SQR21 AHM67346.1     1
 PPYC1_07190   Paenibacillus polymyxa YC0136 APB70154.1     1
 PPYC2_07570   Paenibacillus polymyxa YC0573 APB74847.1     1
 PRIO_3446   Paenibacillus riograndensis SBR5 CQR55849.1     1
 BBD42_25070   Paenibacillus sp. BIHB4019 ANY69390.1     1
 DCC85_01260   Paenibacillus sp. CAA11 AWB42992.1     1
 P40081_04040   Paenibacillus sp. FSL P4-0081 AIQ27461.1     1
 R50912_03665   Paenibacillus sp. FSL R5-0912 AIQ39244.1     1
 endo-β-1,4-glucanase (Endo5A) 3.2.1.4 Paenibacillus sp. ICGEB2008 / MTCC 5639 AEB00655.1     1
 ASL14_19880   Paenibacillus sp. IHB B 3084 ALP38105.1     1
 endo-β-1,4-glucanase (Egl) 3.2.1.4 Paenibacillus sp. KCTC8848P AAL83749.1 Q8RPZ3   1
 C0638_14995   Paenibacillus sp. lzh-N1 AUO07745.1     1
 HPL003_26960   Paenibacillus terrae HPL-003 AET62104.1     1
 SAMN04489860_0019   Paraoerskovia marina DSM 22126 SDR77692.1     1
 AAW51_2245   [Polyangium] brachysporum DSM 7029 AKJ28936.1     1
 Riv7116_4185   Rivularia sp. PCC 7116 AFY56617.1     1
 Riv7116_0722   Rivularia sp. PCC 7116 AFY53310.1     1
 RD2015_747   Roseateles depolymerans KCTC 42856 ALV05243.1     1
 RD2015_749   Roseateles depolymerans KCTC 42856 ALV05245.1     1
 RGI145_02340   Roseomonas gilardii U14-5 APT56123.1     1
 AD2_02839   Ruminiclostridium thermocellum AD2 ALX09817.1     1
 AD2_01719   Ruminiclostridium thermocellum AD2 ALX08709.1     1
 AD2_00416   Ruminiclostridium thermocellum AD2 ALX07424.1     1
 AD2_01837   Ruminiclostridium thermocellum AD2 ALX08827.1     1
 Cthe_0405 (CelL)   Ruminiclostridium thermocellum ATCC 27405 ABN51643.1 A3DCG4   1
 endo-β-1,4-glucanase B (CelB;EgB;Cthe_0536) (Cel5A) 3.2.1.4 Ruminiclostridium thermocellum ATCC 27405 ABN51772.1 P04956   1
 Cthe_2147 (CelO) (Cel5F)   Ruminiclostridium thermocellum ATCC 27405 ABN53350.1 A3DHC1   1
 endo-β-1,4-glucanase G (CelG;Cthe_2872) (Cel5D) 3.2.1.4 Ruminiclostridium thermocellum ATCC 27405 ABN54070.1 Q05332   1
 Clo1313_1701   Ruminiclostridium thermocellum DSM 1313 ADU74758.1     1
 Clo1313_1816   Ruminiclostridium thermocellum DSM 1313 ADU74872.1     1
 Clo1313_2805   Ruminiclostridium thermocellum DSM 1313 ADU75785.1     1
 Clo1313_0413   Ruminiclostridium thermocellum DSM 1313 ADU73502.1     1
 LQRI_1836   Ruminiclostridium thermocellum DSM 2360 LQRI ANV76577.1     1
 LQRI_1720   Ruminiclostridium thermocellum DSM 2360 LQRI ANV76461.1     1
 LQRI_2850   Ruminiclostridium thermocellum DSM 2360 LQRI ANV77591.1     1
 LQRI_0416   Ruminiclostridium thermocellum DSM 2360 LQRI ANV75163.1     1
 endo-1,4-β-glucanase (CelL)   Ruminiclostridium thermocellum F7 CAK18680.1 Q1JR84   1
 cellobiohydrolase (CelO) (Cel5F) 3.2.1.91 Ruminiclostridium thermocellum F7 CAB76938.1 Q9L3J2   1
 endo-β-1,4-glucanase B (CelB;EgB) (Cel5A) 3.2.1.4 Ruminiclostridium thermocellum NCIB 10682 CAA27266.1 P04956   1
 endo-β-1,4-glucanase G (CelG) (Cel5D) 3.2.1.4 Ruminiclostridium thermocellum NCIB 10682 CAA49187.1 Q05332   1
 Rumal_1049   Ruminococcus albus 7 = DSM 20455 ADU21575.1 E0L9A2   1
 Rumal_2017   Ruminococcus albus 7 = DSM 20455 ADU22510.1 E0LAT0   1
 Rumal_2777   Ruminococcus albus 7 = DSM 20455 ADU23246.1 E0L654   1
 cellulase (Cel5G)   Ruminococcus albus 8 AAT48117.1 Q6GVN1   1
 lichenase (Ra2830;CUS_5609) 3.2.1.73 Ruminococcus albus 8 EGC04285.1
ZP_08157835.1
    1
 RBI_I00497   Ruminococcus bicirculans 80/3 CCO04221.1     1
 endo-β-1,4-glucanase (GH5B;RUM_06330) (Cel5B) 3.2.1.4 Ruminococcus champanellensis 18P13 = JCM 17042 CBL16847.1 D4LB52   1
 Strop_2684   Salinispora tropica CNB-440 ABP55128.1 A4X8C8   1
 SAMD00079811_23510   Scytonema sp. HK-05 NIES-2130 BAY44749.1     1
 SAMD00079811_39570   Scytonema sp. HK-05 NIES-2130 BAY46348.1     1
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