Glycoside Hydrolase Family 5 / Subf 1

Activities in Familyendo-β-1,4-glucanase / cellulase (EC 3.2.1.4); endo-β-1,4-xylanase (EC 3.2.1.8); β-glucosidase (EC 3.2.1.21); β-mannosidase (EC 3.2.1.25); β-glucosylceramidase (EC 3.2.1.45); glucan β-1,3-glucosidase (EC 3.2.1.58); exo-β-1,4-glucanase / cellodextrinase (EC 3.2.1.74); glucan endo-1,6-β-glucosidase (EC 3.2.1.75); mannan endo-β-1,4-mannosidase (EC 3.2.1.78); cellulose β-1,4-cellobiosidase (EC 3.2.1.91); steryl β-glucosidase (EC 3.2.1.104); endoglycoceramidase (EC 3.2.1.123); chitosanase (EC 3.2.1.132); β-primeverosidase (EC 3.2.1.149); xyloglucan-specific endo-β-1,4-glucanase (EC 3.2.1.151); endo-β-1,6-galactanase (EC 3.2.1.164); β-1,3-mannanase (EC 3.2.1.-); arabinoxylan-specific endo-β-1,4-xylanase (EC 3.2.1.-); mannan transglycosylase (EC 2.4.1.-); lichenase / endo-β-1,3-1,4-glucanase (EC 3.2.1.73); β-glycosidase (EC 3.2.1.-); endo-β-1,3-glucanase / laminarinase (EC 3.2.1.39); β-N-acetylhexosaminidase (EC 3.2.1.52); chitosanase (EC 3.2.1.132); β-D-galactofuranosidase (EC 3.2.1.146); β-galactosylceramidase (EC 3.2.1.46);
Activities in Sub Family
Mechanism Retaining
ClanGH-A
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental)
NoteOnce known as cellulase family A; many members have been assigned to subfamilies as described by Aspeborg et al. (2012) BMC Evol Biol. 12(1):186 (PMID: 22992189).
External resourcesCAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; NZYTech; PROZOMIX;
Statistics GenBank accession (751); Uniprot accession (102); PDB accession (15); 3D entries (3); cryst (0)
| 1 | 2 | 3 | 4 | 5 | 6 | 7 |
Bacteria
Protein Name EC#Organism GenBankUniprotPDB/3DSubf
 CFP59_05028   Streptomyces sp. M56 AUA12875.1     1
 EJ357_20285   Streptomyces sp. MK-45 AZQ35546.1     1
 C6376_11910   Streptomyces sp. P3 AVV42024.1     1
 F750_5941   Streptomyces sp. PAMC 26508 AGJ58369.1     1
 GFH48_02005   Streptomyces sp. QMT-28 QFZ72191.1     1
 D7Y56_27960   Streptomyces sp. S501 QBR09424.1     1
 B9S64_28810   Streptomyces sp. SM18 AWL41642.1     1
 SSPO_054340 (fragment)   Streptomyces sporoclivatus NBRC 100767 BBJ42716.1     1
 SSPO_054350 (fragment)   Streptomyces sporoclivatus NBRC 100767 BBJ42717.1     1
 Strvi_8930   Streptomyces violaceusniger Tu 4113 AEM88231.1     1
 DKM19_02670   Streptosporangium sp. caverna AWS40401.1     1
 SCL_1792   Sulfuricaulis limicola HA5 BAV34090.1     1
 TJEJU_3612   Tenacibaculum jejuense KCTC 22618 SNR17255.1     1
 TERTU_3565   Teredinibacter turnerae T7901 ACR11017.1 C5BRI4   1
 endoglucanase (EGtf2) (Cel5B) 3.2.1.4 Thermobifida fusca TM51 AAP56348.1 Q7X2N2   1
 endoglucanase 5B (Tfu_2712) (Cel5B) 3.2.1.4 Thermobifida fusca YX AAZ56745.1 Q47LC7   1
 multidomain cellulase   thermophilic anaerobe NA10 BAA22939.1 O24820   1
 KTC_24100   Thermosporothrix sp. COM3 BBH87659.1     1
 endocellulase (CelA) (Cel5A) 3.2.1.4 Thermus caldophilus GK24 AAK60011.1 Q93Q07   1
 TCCBUS3UF1_1700   Thermus sp. CCB_US3_UF1 AEV15219.1     1
 Trad_1441   Truepera radiovictrix DSM 17093 ADI14563.1 D7CX55   1
 CelE2, partial   uncultured bacterium ANN44164.1     1
 VAB18032_22475   Verrucosispora maris AB-18-032 AEB45595.1     1
 EQG49_04655   Weissella sp. 26KH-42 QBO35805.1     1
 XALc_2967   Xanthomonas albilineans GPE PC73 CBA17444.1     1
 XALc_2969   Xanthomonas albilineans GPE PC73 CBA17446.1     1
 AKJ12_08070   Xanthomonas arboricola pv. juglandis Xaj 417 AKU49746.1     1
 F6Y24_08865   Xanthomonas arboricola pv. pruni 15-088 QEX77129.1     1
 XACM_0615 (EngxcA)   Xanthomonas axonopodis pv. citrumelo F1 AEO40920.1     1
 Xcom_18885   Xanthomonas axonopodis pv. commiphoreae LMG26789 AYO96787.1     1
 XAC29_03125   Xanthomonas axonopodis Xac29-1 AGH76155.1     1
 XB05_20710   Xanthomonas campestris 17 AKC80882.1     1
 NX80_018250   Xanthomonas campestris pv. arecae NCPPB 2649 AZR28079.1     1
 endo-β-1,4-glucanase (EngXCA;EngA) (frameshift) 3.2.1.4 Xanthomonas campestris pv. campestris CAC18529.1
AAA27612.1
Q9EVR6 4TUF[A,B,C,D] 1
 AAW18_17365   Xanthomonas campestris pv. campestris 17 ALE70057.1     1
 AEA01_03155   Xanthomonas campestris pv. campestris 4013 AKS19035.1     1
 AEA00_03125   Xanthomonas campestris pv. campestris ICMP 21080 AKS15008.1     1
 Xcc1_06720 (EngxcA)   Xanthomonas campestris pv. campestris MAFF106712 BBJ94942.1     1
 Xcc3_06690 (EngxcA)   Xanthomonas campestris pv. campestris MAFF302021 BBJ99361.1     1
 XC_0639   Xanthomonas campestris pv. campestris str. 8004 AAY47719.1 Q4UZ04   1
 endo-β-1,4-glucanase (EngXCA;XccEG;XCC3521) 3.2.1.4 Xanthomonas campestris pv. campestris str. ATCC 33913 AAM42791.1
NP_638867.1
P19487   1
 xcc-b100_0675 (EngXCA)   Xanthomonas campestris pv. campestris str. B100 CAP50014.1 P19487   1
 DFG55_04210   Xanthomonas campestris pv. campestris Xcc8004_Xcc1 QCX65775.1     1
 DFG54_03165   Xanthomonas campestris pv. campestris Xcc8004_Xcc2 QCX69907.1     1
 KWO_003210   Xanthomonas campestris pv. musacearum NCPPB 4379 AZR29698.1     1
 XCR_3859 (EngXCA)   Xanthomonas campestris pv. raphani 756C AEL08719.1     1
 XCV0670 (EngXCA)   Xanthomonas campestris pv. vesicatoria str. 85-10 CAJ22301.1
AOY68300.1
Q3BXW2   1
 AC028_09270   Xanthomonas citri pv. aurantifolii 1566 AMV06963.1     1
 TP45_02600   Xanthomonas citri pv. aurantifolii FDC 1561 ARE55338.1     1
 CLM98_03770   Xanthomonas citri pv. citri 03-1638-1-1 AUZ49783.1     1
 J152_00729   Xanthomonas citri pv. citri 5208 AJZ38424.1     1
 J165_03949   Xanthomonas citri pv. citri AW13 AJZ46035.1     1
 J166_03953   Xanthomonas citri pv. citri AW14 AJZ50654.1     1
 J167_03954   Xanthomonas citri pv. citri AW15 AJZ55275.1     1
 J168_03950   Xanthomonas citri pv. citri AW16 AJZ68066.1     1
 J170_00725   Xanthomonas citri pv. citri BL18 AJZ33955.1     1
 J171_00727   Xanthomonas citri pv. citri FB19 AJZ29492.1     1
 J154_00733   Xanthomonas citri pv. citri gd2 AJZ25074.1     1
 J155_00733   Xanthomonas citri pv. citri gd3 AJZ20648.1     1
 AB890_03190   Xanthomonas citri pv. citri jx-6 AKM23858.1     1
 J156_00734   Xanthomonas citri pv. citri jx4 AJZ16225.1     1
 J157_00734   Xanthomonas citri pv. citri jx5 AJZ11796.1     1
 BJD09_13295   Xanthomonas citri pv. citri LH201 APR25044.1     1
 BI316_04650   Xanthomonas citri pv. citri LH276 APR18926.1     1
 BI315_16605   Xanthomonas citri pv. citri LJ207-7 APR16186.1     1
 BI314_21610   Xanthomonas citri pv. citri LL074-4 APR12374.1     1
 J172_00726   Xanthomonas citri pv. citri mf20 AJZ07325.1     1
 J162_00731   Xanthomonas citri pv. citri MN10 AJZ02902.1     1
 J163_00731   Xanthomonas citri pv. citri MN11 AJY98478.1     1
 J164_00731   Xanthomonas citri pv. citri MN12 AJY94054.1     1
 J169_00731   Xanthomonas citri pv. citri NT17 AJY89583.1     1
 XAC0612 (EngXCA)   Xanthomonas citri pv. citri str. 306 AAM35501.1
NP_640965.1
Q8PPS3   1
 B7L65_20635   Xanthomonas citri pv. citri TX160042 ARR19057.1     1
 B7L66_23830   Xanthomonas citri pv. citri TX160149 ARR14873.1     1
 B7L67_03845   Xanthomonas citri pv. citri TX160197 ARR20822.1     1
 COR42_03320   Xanthomonas citri pv. citri Xcc29-1 AYL19513.1     1
 CPA10_03320   Xanthomonas citri pv. citri Xcc49 AYL23953.1     1
 CKU38_00658   Xanthomonas citri pv. fuscans FX01 ATB57205.1     1
 AC613_03125   Xanthomonas citri pv. fuscans ISO118C1 AZU16111.1     1
 AC614_03125   Xanthomonas citri pv. fuscans ISO118C5 AZU91372.1     1
 AC612_03125   Xanthomonas citri pv. fuscans ISO12C3 AZU20259.1     1
 XFF4834R_chr06240   Xanthomonas citri pv. fuscans str. 4834-R CDF60261.1     1
 FPL00_03590   Xanthomonas citri pv. glycines 1018 QDS06067.1     1
 FPL03_03540   Xanthomonas citri pv. glycines 1157 QDS10345.1     1
 FPL04_03250   Xanthomonas citri pv. glycines 2098 QDS14753.1     1
 FPK90_03550   Xanthomonas citri pv. glycines 8ra QDR43878.1     1
 C2859_03545   Xanthomonas citri pv. glycines EB08 QEQ72212.1     1
 FPL05_03730   Xanthomonas citri pv. glycines K2 QDS18975.1     1
 A9D66_03375   Xanthomonas citri pv. glycines str. 12-2 ARV21669.1     1
 BHE84_21365   Xanthomonas citri pv. glycines str. 8ra AOY64452.1     1
 CIW71_20430   Xanthomonas citri pv. malvacearum AR81009 ASY85998.1     1
 GH913_08110   Xanthomonas citri pv. malvacearum HD-1 QGL16765.1     1
 CIW72_03370   Xanthomonas citri pv. malvacearum MS14003 ASY87580.1     1
 BGK55_03260   Xanthomonas citri pv. malvacearum MSCT AOL18402.1     1
 APY29_19075   Xanthomonas citri pv. malvacearum XcmH1005 ASN02827.1     1
 APY30_18890   Xanthomonas citri pv. malvacearum XcmN1003 ASN11029.1     1
 XcfCFBP4885P_17120   Xanthomonas citri pv. phaseoli var. fuscans CFBP4885 ATS64921.1     1
 XcfCFBP6165P_03390   Xanthomonas citri pv. phaseoli var. fuscans CFBP6165 ATS66692.1     1
 XcfCFBP6166P_21335   Xanthomonas citri pv. phaseoli var. fuscans CFBP6166 ATS73763.1     1
 XcfCFBP6167P_10490   Xanthomonas citri pv. phaseoli var. fuscans CFBP6167 ATS88667.1     1
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