Glycoside Hydrolase Family 5 / Subf 1

Activities in Familyendo-β-1,4-glucanase / cellulase (EC 3.2.1.4); endo-β-1,4-xylanase (EC 3.2.1.8); β-glucosidase (EC 3.2.1.21); β-mannosidase (EC 3.2.1.25); β-glucosylceramidase (EC 3.2.1.45); glucan β-1,3-glucosidase (EC 3.2.1.58); exo-β-1,4-glucanase / cellodextrinase (EC 3.2.1.74); glucan endo-1,6-β-glucosidase (EC 3.2.1.75); mannan endo-β-1,4-mannosidase (EC 3.2.1.78); cellulose β-1,4-cellobiosidase (EC 3.2.1.91); steryl β-glucosidase (EC 3.2.1.104); endoglycoceramidase (EC 3.2.1.123); chitosanase (EC 3.2.1.132); β-primeverosidase (EC 3.2.1.149); xyloglucan-specific endo-β-1,4-glucanase (EC 3.2.1.151); endo-β-1,6-galactanase (EC 3.2.1.164); β-1,3-mannanase (EC 3.2.1.-); arabinoxylan-specific endo-β-1,4-xylanase (EC 3.2.1.-); mannan transglycosylase (EC 2.4.1.-); lichenase / endo-β-1,3-1,4-glucanase (EC 3.2.1.73); β-glycosidase (EC 3.2.1.-); endo-β-1,3-glucanase / laminarinase (EC 3.2.1.39); β-N-acetylhexosaminidase (EC 3.2.1.52); chitosanase (EC 3.2.1.132); β-D-galactofuranosidase (EC 3.2.1.146); β-galactosylceramidase (EC 3.2.1.46); ; β-rutinosidase /α-L-rhamnose-(1,6)-β-D-glucosidase (EC 3.2.1.-); α-L-arabinofuranosidase (EC 3.2.1.55)
Activities in Sub Family
Mechanism Retaining
ClanGH-A
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental)
NoteOnce known as cellulase family A; many members have been assigned to subfamilies as described by Aspeborg et al. (2012) BMC Evol Biol. 12(1):186 (PMID: 22992189).
External resourcesCAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; NZYTech; PROZOMIX;
Statistics GenBank accession (803); Uniprot accession (102); PDB accession (15); 3D entries (3); cryst (0)
All (763) Archaea (11) Bacteria (689) Eukaryota (50) Viruses (11) unclassified (2) Structure (3) Characterized (34)
| 1 | 2 | 3 | 4 | 5 | 6 | 7 |
Bacteria
Protein Name EC#Organism GenBankUniprotPDB/3DSubf
 cellulase (CBH-B;CelB;Csac_1078) 3.2.1.4 Caldicellulosiruptor saccharolyticus DSM 8903 ABP66692.1 A4XIF7   1
 multidomain endoglucanase (CelB)   Caldicellulosiruptor sp. Tok7B.1 AAD30364.1 Q9X3P6   1
 NIES22_60310   Calothrix brevissima NIES-22 BAY65919.1     1
 NIES267_13610   Calothrix parasitica NIES-267 BAY81883.1     1
 NIES267_49770   Calothrix parasitica NIES-267 BAY85477.1     1
 IJ00_21580   Calothrix sp. 336/3 AKG24782.1     1
 IJ00_14720   Calothrix sp. 336/3 AKG22350.1     1
 IJ00_24435   Calothrix sp. 336/3 AKG24820.1     1
 NIES2100_07100   Calothrix sp. NIES-2100 BAY20966.1     1
 NIES3974_19500   Calothrix sp. NIES-3974 BAZ05303.1     1
 NIES4071_47850   Calothrix sp. NIES-4071 BAZ12951.1     1
 NIES4071_04830   Calothrix sp. NIES-4071 BAZ08678.1     1
 NIES4101_40790   Calothrix sp. NIES-4101 BAZ38144.1     1
 NIES4101_46910   Calothrix sp. NIES-4101 BAZ38749.1     1
 NIES4105_04820   Calothrix sp. NIES-4105 BAZ54829.1     1
 NIES4105_47790   Calothrix sp. NIES-4105 BAZ59097.1     1
 Cal6303_3022   Calothrix sp. PCC 6303 AFZ01969.1     1
 Cal7507_3091   Calothrix sp. PCC 7507 AFY33503.1     1
 F6R98_03160   Candidatus Methylospira mobilis Shm1 QFY41750.1     1
 A7sIIA15_04770   Candidatus Planktophila vernalis ASY20173.1     1
 Caci_4214   Catenulispora acidiphila DSM 44928 ACU73078.1 C7QI33   1
 endo-β-1,4-glucanase D (CenD;Celf_1924) (Cel5A) 3.2.1.4 Cellulomonas fimi ATCC 484 AAA23089.1
AEE46054.1
P50400   1
 NCTC7547_01960 (Cbhb_1)   Cellulomonas fimi NCTC7547 VEH31446.1     1
 endo-β-1,4-glucanase B (CelB;CflB;CelCflB;SP18) 3.2.1.4 Cellulomonas flavigena CDBB-531 AAD48494.3
AAD48494.2
Q9S3V3   1
 Cfla_1897   Cellulomonas flavigena DSM 20109 ADG74794.1 D5UEY4   1
 Celgi_1696   Cellulomonas gilvus ATCC 13127 AEI12207.1     1
 E5225_08430   Cellulomonas shaoxiangyii Z28 QCB93582.1     1
 GXP71_06520   Cellulomonas sp. H30R-01 QHT58264.1     1
 CBP52_04725   Cellulomonas sp. PSBB021 ASR54546.1     1
 Clole_2598   Cellulosilyticum lentocellum DSM 5427 ADZ84301.1     1
 CGSCsYakCAS_16179 (Cel5B)   Cellulosilyticum ruminicola CGMCC 1.5065 ACZ98599.1 D2KFJ7   1
 EKH84_15865   Cellulosilyticum sp. WCF-2 QEH69789.1     1
 endoglucanase (CelB)   Clavibacter michiganensis subsp. capsici 1101 QGL06814.1     1
 GW570_11760   Clavibacter michiganensis subsp. capsici 1101 QIS45712.1     1
 endoglucanase (CelB)   Clavibacter michiganensis subsp. capsici 1106 QGL06815.1     1
 GW571_11790   Clavibacter michiganensis subsp. capsici 1106 QIS42769.1     1
 GW572_12210   Clavibacter michiganensis subsp. capsici 1207 QIS39854.1     1
 AES38_11775 (CelB)   Clavibacter michiganensis subsp. capsici PF008 ALD13503.1     1
 BEH62_15190   Clavibacter michiganensis subsp. insidiosus ATCC 10253 AWG02938.1     1
 VO01_15470   Clavibacter michiganensis subsp. insidiosus R1-1 AJW80648.1     1
 VO01_11370   Clavibacter michiganensis subsp. insidiosus R1-1 AJW79649.1     1
 BEH61_03535   Clavibacter michiganensis subsp. insidiosus R1-3 AWF97569.1     1
 BEH61_15105   Clavibacter michiganensis subsp. insidiosus R1-3 AWF99834.1     1
 cellulase, partial (CelA) (fragment)   Clavibacter michiganensis subsp. michiganensis 0310 AHZ96450.1     1
 cellulase, partial (CelA) (fragment)   Clavibacter michiganensis subsp. michiganensis 0312 AHZ96451.1     1
 cellulase, partial (CelA) (fragment)   Clavibacter michiganensis subsp. michiganensis 0314 AHZ96452.1     1
 cellulase, partial (CelA) (fragment)   Clavibacter michiganensis subsp. michiganensis 0315 AHZ96453.1     1
 cellulase, partial (CelA) (fragment)   Clavibacter michiganensis subsp. michiganensis 04100 AHZ96454.1     1
 cellulase, partial (CelA) (fragment)   Clavibacter michiganensis subsp. michiganensis 04101 AHZ96455.1     1
 cellulase, partial (CelA) (fragment)   Clavibacter michiganensis subsp. michiganensis 04106 AHZ96456.1     1
 cellulase, partial (CelA) (fragment)   Clavibacter michiganensis subsp. michiganensis 04108 AHZ96457.1     1
 cellulase, partial (CelA) (fragment)   Clavibacter michiganensis subsp. michiganensis 0426 AHZ96458.1     1
 cellulase, partial (CelA) (fragment)   Clavibacter michiganensis subsp. michiganensis 0459 AHZ96459.1     1
 cellulase, partial (CelA) (fragment)   Clavibacter michiganensis subsp. michiganensis 0572 AHZ96460.1     1
 cellulase, partial (CelA) (fragment)   Clavibacter michiganensis subsp. michiganensis 0580 AHZ96461.1     1
 cellulase, partial (CelA) (fragment)   Clavibacter michiganensis subsp. michiganensis 0581 AHZ96462.1     1
 cellulase, partial (CelA) (fragment)   Clavibacter michiganensis subsp. michiganensis 0582 AHZ96463.1     1
 cellulase, partial (CelA) (fragment)   Clavibacter michiganensis subsp. michiganensis 06124 AHZ96464.1     1
 cellulase, partial (CelA) (fragment)   Clavibacter michiganensis subsp. michiganensis 0651 AHZ96465.1     1
 cellulase, partial (CelA) (fragment)   Clavibacter michiganensis subsp. michiganensis 0654 AHZ96466.1     1
 cellulase, partial (CelA) (fragment)   Clavibacter michiganensis subsp. michiganensis 0676 AHZ96467.1     1
 cellulase, partial (CelA) (fragment)   Clavibacter michiganensis subsp. michiganensis 0687 AHZ96468.1     1
 cellulase, partial (CelA) (fragment)   Clavibacter michiganensis subsp. michiganensis 0690 AHZ96469.1     1
 cellulase, partial (CelA) (fragment)   Clavibacter michiganensis subsp. michiganensis 0691 AHZ96470.1     1
 cellulase, partial (CelA) (fragment)   Clavibacter michiganensis subsp. michiganensis 0692 AHZ96471.1     1
 cellulase, partial (CelA) (fragment)   Clavibacter michiganensis subsp. michiganensis 0748 AHZ96472.1     1
 cellulase, partial (CelA) (fragment)   Clavibacter michiganensis subsp. michiganensis 0763 AHZ96473.1     1
 cellulase, partial (CelA) (fragment)   Clavibacter michiganensis subsp. michiganensis 0767 AHZ96474.1     1
 cellulase, partial (CelA) (fragment)   Clavibacter michiganensis subsp. michiganensis 0775 AHZ96475.1     1
 cellulase, partial (CelA) (fragment)   Clavibacter michiganensis subsp. michiganensis 0779 AHZ96476.1     1
 cellulase, partial (CelA) (fragment)   Clavibacter michiganensis subsp. michiganensis 0780 AHZ96477.1     1
 cellulase, partial (CelA) (fragment)   Clavibacter michiganensis subsp. michiganensis 0784 AHZ96478.1     1
 cellulase, partial (CelA) (fragment)   Clavibacter michiganensis subsp. michiganensis 0785 AHZ96479.1     1
 cellulase, partial (CelA) (fragment)   Clavibacter michiganensis subsp. michiganensis 08223 AHZ96480.1     1
 cellulase, partial (CelA) (fragment)   Clavibacter michiganensis subsp. michiganensis 08224 AHZ96481.1     1
 cellulase, partial (CelA) (fragment)   Clavibacter michiganensis subsp. michiganensis 09081 AHZ96482.1     1
 cellulase, partial (CelA) (fragment)   Clavibacter michiganensis subsp. michiganensis 09085 AHZ96483.1     1
 cellulase, partial (CelA) (fragment)   Clavibacter michiganensis subsp. michiganensis 09086 AHZ96484.1     1
 cellulase, partial (CelA) (fragment)   Clavibacter michiganensis subsp. michiganensis 11015 AHZ96485.1     1
 cellulase, partial (CelA) (fragment)   Clavibacter michiganensis subsp. michiganensis 12069 AHZ96486.1     1
 cellulase, partial (CelA) (fragment)   Clavibacter michiganensis subsp. michiganensis 12083 AHZ96487.1     1
 cellulase, partial (CelA) (fragment)   Clavibacter michiganensis subsp. michiganensis 13048 AHZ96488.1     1
 cellulase, partial (CelA) (fragment)   Clavibacter michiganensis subsp. michiganensis 13054 AHZ96489.1     1
 cellulase, partial (CelA) (fragment)   Clavibacter michiganensis subsp. michiganensis 13084 AHZ96490.1     1
 cellulase, partial (CelA) (fragment)   Clavibacter michiganensis subsp. michiganensis 13090 AHZ96491.1     1
 cellulase, partial (CelA) (fragment)   Clavibacter michiganensis subsp. michiganensis 13091 AHZ96492.1     1
 cellulase, partial (CelA) (fragment)   Clavibacter michiganensis subsp. michiganensis 13109 AHZ96493.1     1
 cellulase, partial (CelA) (fragment)   Clavibacter michiganensis subsp. michiganensis 13115 AHZ96494.1     1
 cellulase, partial (CelA) (fragment)   Clavibacter michiganensis subsp. michiganensis 13117 AHZ96495.1     1
 cellulase, partial (CelA) (fragment)   Clavibacter michiganensis subsp. michiganensis 13129 AHZ96496.1     1
 cellulase, partial (CelA) (fragment)   Clavibacter michiganensis subsp. michiganensis 13134 AHZ96497.1     1
 CelA   Clavibacter michiganensis subsp. michiganensis BT0505 AHN16207.1     1
 CelA (fragment)   Clavibacter michiganensis subsp. michiganensis Cmm_MKH AEM65927.1
AEM65928.1
    1
 GRD74_15765   Clavibacter michiganensis subsp. michiganensis MSF322 QIT13040.1     1
 CMM_2443 (CelB)   Clavibacter michiganensis subsp. michiganensis NCPPB 382 CAN02524.1 A5CTT9   1
 bifunctional cellulase / expansin (CelA;pCM1_0020) 3.2.1.4 Clavibacter michiganensis subsp. michiganensis NCPPB 382 CAA44467.2
CAM98473.1
Q9K5C7   1
 EFE39_15410   Clavibacter michiganensis subsp. michiganensis UF1 QGV76751.1     1
 GRD61_16045   Clavibacter michiganensis subsp. michiganensis VL527 QIT16217.1     1
 GRD61_12870   Clavibacter michiganensis subsp. michiganensis VL527 QIT15432.1     1
 EGX35_11885   Clavibacter michiganensis subsp. nebraskensis 61-1 QGV73059.1     1
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