Glycoside Hydrolase Family 5 / Subf 1

Activities in Familyendo-β-1,4-glucanase / cellulase (EC 3.2.1.4); endo-β-1,4-xylanase (EC 3.2.1.8); β-glucosidase (EC 3.2.1.21); β-mannosidase (EC 3.2.1.25); β-glucosylceramidase (EC 3.2.1.45); glucan β-1,3-glucosidase (EC 3.2.1.58); licheninase (EC 3.2.1.73); exo-β-1,4-glucanase / cellodextrinase (EC 3.2.1.74); glucan endo-1,6-β-glucosidase (EC 3.2.1.75); mannan endo-β-1,4-mannosidase (EC 3.2.1.78); cellulose β-1,4-cellobiosidase (EC 3.2.1.91); steryl β-glucosidase (EC 3.2.1.104); endoglycoceramidase (EC 3.2.1.123); chitosanase (EC 3.2.1.132); β-primeverosidase (EC 3.2.1.149); xyloglucan-specific endo-β-1,4-glucanase (EC 3.2.1.151); endo-β-1,6-galactanase (EC 3.2.1.164); hesperidin 6-O-α-L-rhamnosyl-β-glucosidase (EC 3.2.1.168); β-1,3-mannanase (EC 3.2.1.-); arabinoxylan-specific endo-β-1,4-xylanase (EC 3.2.1.-); mannan transglycosylase (EC 2.4.1.-)
Activities in Sub Family
Mechanism Retaining
ClanGH-A
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental)
NoteOnce known as cellulase family A; many members have been assigned to subfamilies as described by Aspeborg et al. (2012) BMC Evol Biol. 12(1):186 (PMID: 22992189).
External resourcesCAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; NZYTech; PROZOMIX;
Statistics GenBank accession (531); Uniprot accession (102); PDB accession (15); 3D entries (3); cryst (0)
| 1 | 2 | 3 | 4 | 5 |
Bacteria
Protein Name EC#Organism GenBankUniprotPDB/3DSubf
 TCCBUS3UF1_1700   Thermus sp. CCB_US3_UF1 AEV15219.1     1
 Trad_1441   Truepera radiovictrix DSM 17093 ADI14563.1 D7CX55   1
 CelE2, partial   uncultured bacterium ANN44164.1     1
 VAB18032_22475   Verrucosispora maris AB-18-032 AEB45595.1     1
 XALc_2967   Xanthomonas albilineans GPE PC73 CBA17444.1     1
 XALc_2969   Xanthomonas albilineans GPE PC73 CBA17446.1     1
 AKJ12_08070   Xanthomonas arboricola pv. juglandis Xaj 417 AKU49746.1     1
 XAC0612 (EngXCA)   Xanthomonas axonopodis pv. citri str. 306 AAM35501.1
NP_640965.1
Q8PPS3   1
 XACM_0615 (EngxcA)   Xanthomonas axonopodis pv. citrumelo F1 AEO40920.1     1
 XAC29_03125   Xanthomonas axonopodis Xac29-1 AGH76155.1     1
 XB05_20710   Xanthomonas campestris 17 AKC80882.1     1
 endo-β-1,4-glucanase (EngXCA;EngA) (frameshift) 3.2.1.4 Xanthomonas campestris pv. campestris CAC18529.1
AAA27612.1
Q9EVR6 4TUF[A,B,C,D] 1
 AAW18_17365   Xanthomonas campestris pv. campestris 17 ALE70057.1     1
 AEA01_03155   Xanthomonas campestris pv. campestris 4013 AKS19035.1     1
 AEA00_03125   Xanthomonas campestris pv. campestris ICMP 21080 AKS15008.1     1
 XC_0639   Xanthomonas campestris pv. campestris str. 8004 AAY47719.1 Q4UZ04   1
 endo-β-1,4-glucanase (EngXCA;XccEG;XCC3521) 3.2.1.4 Xanthomonas campestris pv. campestris str. ATCC 33913 AAM42791.1
NP_638867.1
P19487   1
 xcc-b100_0675 (EngXCA)   Xanthomonas campestris pv. campestris str. B100 CAP50014.1 P19487   1
 XCR_3859 (EngXCA)   Xanthomonas campestris pv. raphani 756C AEL08719.1     1
 XCV0670 (EngXCA)   Xanthomonas campestris pv. vesicatoria str. 85-10 CAJ22301.1
AOY68300.1
Q3BXW2   1
 AB890_03190   Xanthomonas citri pv. citri jx-6 AKM23858.1     1
 BJD09_13295   Xanthomonas citri pv. citri LH201 APR25044.1     1
 BI316_04650   Xanthomonas citri pv. citri LH276 APR18926.1     1
 BI315_16605   Xanthomonas citri pv. citri LJ207-7 APR16186.1     1
 BI314_21610   Xanthomonas citri pv. citri LL074-4 APR12374.1     1
 A9D66_03375   Xanthomonas citri pv. glycines str. 12-2 ARV21669.1     1
 BHE84_21365   Xanthomonas citri pv. glycines str. 8ra AOY64452.1     1
 BGK55_03260   Xanthomonas citri pv. malvacearum MSCT AOL18402.1     1
 XcfCFBP4885P_17120   Xanthomonas citri pv. phaseoli var. fuscans CFBP4885 ATS64921.1     1
 XcfCFBP6165P_03390   Xanthomonas citri pv. phaseoli var. fuscans CFBP6165 ATS66692.1     1
 XcfCFBP6166P_21335   Xanthomonas citri pv. phaseoli var. fuscans CFBP6166 ATS73763.1     1
 XcfCFBP6167P_10490   Xanthomonas citri pv. phaseoli var. fuscans CFBP6167 ATS88667.1     1
 XcfCFBP6975P_13445   Xanthomonas citri pv. phaseoli var. fuscans CFBP6975 ATS76600.1     1
 XcfCFBP6988P_05445   Xanthomonas citri pv. phaseoli var. fuscans CFBP6988R ATS37620.1     1
 XcfCFBP6989P_15025   Xanthomonas citri pv. phaseoli var. fuscans CFBP6989 ATS43571.1     1
 XcfCFBP6990P_02320   Xanthomonas citri pv. phaseoli var. fuscans CFBP6990 ATS45622.1     1
 XcfCFBP6991P_09135   Xanthomonas citri pv. phaseoli var. fuscans CFBP6991 ATS84113.1     1
 XcfCFBP6992P_05340   Xanthomonas citri pv. phaseoli var. fuscans CFBP6992 ATS50379.1     1
 XcfCFBP6994P_14065   Xanthomonas citri pv. phaseoli var. fuscans CFBP6994R ATS56114.1     1
 XcfCFBP6996P_11665   Xanthomonas citri pv. phaseoli var. fuscans CFBP6996R ATS59873.1     1
 XcfCFBP7767P_02880   Xanthomonas citri pv. phaseoli var. fuscans CFBP7767 ATS79023.1     1
 XcvCFBP7111P_21575   Xanthomonas citri pv. vignicola CFBP7111 ASK93751.1     1
 CLM98_03770   Xanthomonas citri subsp. citri 03-1638-1-1 AUZ49783.1     1
 J152_00729   Xanthomonas citri subsp. citri 5208 AJZ38424.1     1
 J151_00735   Xanthomonas citri subsp. citri A306 AJD67204.1     1
 XCAW_03969 (BglC)   Xanthomonas citri subsp. citri Aw12879 AGI09734.1     1
 J165_03949   Xanthomonas citri subsp. citri AW13 AJZ46035.1     1
 J166_03953   Xanthomonas citri subsp. citri AW14 AJZ50654.1     1
 J167_03954   Xanthomonas citri subsp. citri AW15 AJZ55275.1     1
 J168_03950   Xanthomonas citri subsp. citri AW16 AJZ68066.1     1
 J170_00725   Xanthomonas citri subsp. citri BL18 AJZ33955.1     1
 J171_00727   Xanthomonas citri subsp. citri FB19 AJZ29492.1     1
 J154_00733   Xanthomonas citri subsp. citri gd2 AJZ25074.1     1
 J155_00733   Xanthomonas citri subsp. citri gd3 AJZ20648.1     1
 J156_00734   Xanthomonas citri subsp. citri jx4 AJZ16225.1     1
 J157_00734   Xanthomonas citri subsp. citri jx5 AJZ11796.1     1
 J172_00726   Xanthomonas citri subsp. citri mf20 AJZ07325.1     1
 J162_00731   Xanthomonas citri subsp. citri MN10 AJZ02902.1     1
 J163_00731   Xanthomonas citri subsp. citri MN11 AJY98478.1     1
 J164_00731   Xanthomonas citri subsp. citri MN12 AJY94054.1     1
 J169_00731   Xanthomonas citri subsp. citri NT17 AJY89583.1     1
 B7L65_20635   Xanthomonas citri subsp. citri TX160042 ARR19057.1     1
 B7L66_23830   Xanthomonas citri subsp. citri TX160149 ARR14873.1     1
 B7L67_03845   Xanthomonas citri subsp. citri TX160197 ARR20822.1     1
 J158_00732   Xanthomonas citri subsp. citri UI6 AJY85160.1     1
 CIW71_20430   Xanthomonas citri subsp. malvacearum AR81009 ASY85998.1     1
 CIW72_03370   Xanthomonas citri subsp. malvacearum MS14003 ASY87580.1     1
 APY29_19075   Xanthomonas citri subsp. malvacearum XcmH1005 ASN02827.1     1
 APY30_18890   Xanthomonas citri subsp. malvacearum XcmN1003 ASN11029.1     1
 BJD11_19485   Xanthomonas euvesicatoria LMG930 APO91915.1     1
 BER93_02585   Xanthomonas fragariae AOD17201.1     1
 BER92_02580   Xanthomonas fragariae AOD13808.1     1
 NBC2815_03482 (EngxcA)   Xanthomonas fragariae SMQ96802.1     1
 PD885_03476 (EngxcA)   Xanthomonas fragariae SMR00697.1     1
 PD5205_00534 (EngxcA)   Xanthomonas fragariae SMR01854.1     1
 AC028_09270   Xanthomonas fuscans subsp. aurantifolii 1566 AMV06963.1     1
 CKU38_00658   Xanthomonas fuscans subsp. fuscans FX01 ATB57205.1     1
 XFF4834R_chr06240   Xanthomonas fuscans subsp. fuscans str. 4834-R CDF60261.1     1
 BI317_20445   Xanthomonas gardneri ICMP 7383 APP86165.1     1
 BJD10_21715   Xanthomonas gardneri JS749-3 APP81949.1     1
 XJ27_19175   Xanthomonas hortorum B07-007 ASW47829.1     1
 AXO1947_17450   Xanthomonas oryzae pv. oryzae AXO1947 ALS96022.1     1
 ClsA (fragment)   Xanthomonas oryzae pv. oryzae BXO43 AAT35585.1 Q6IT75   1
 XOO4019 (EglXoE)   Xanthomonas oryzae pv. oryzae KACC 10331 AAW77273.1     1
 XOO3789   Xanthomonas oryzae pv. oryzae MAFF 311018 BAE70544.1 Q2NYT3   1
 BVV19_03415   Xanthomonas oryzae pv. oryzae MAI106 AUJ04186.1     1
 BVV09_03405   Xanthomonas oryzae pv. oryzae MAI129 AUJ07855.1     1
 BVV20_03425   Xanthomonas oryzae pv. oryzae MAI134 AUJ11525.1     1
 BVV13_03405   Xanthomonas oryzae pv. oryzae MAI145 AUJ15257.1     1
 BVV16_03405   Xanthomonas oryzae pv. oryzae MAI68 AUI89487.1     1
 BVV17_03405   Xanthomonas oryzae pv. oryzae MAI73 AUI93165.1     1
 BVV18_03415   Xanthomonas oryzae pv. oryzae MAI95 AUI96837.1     1
 BVV10_03410   Xanthomonas oryzae pv. oryzae MAI99 AUJ00507.1     1
 ATY43_15945   Xanthomonas oryzae pv. oryzae PXO145 AOS08814.1     1
 ATY44_03505   Xanthomonas oryzae pv. oryzae PXO211 AOS12769.1     1
 ATY45_03375   Xanthomonas oryzae pv. oryzae PXO236 AOS16942.1     1
 ATY46_19845   Xanthomonas oryzae pv. oryzae PXO282 AOS20556.1     1
 ATY47_19775   Xanthomonas oryzae pv. oryzae PXO524 AOS25545.1     1
 ATY48_19755   Xanthomonas oryzae pv. oryzae PXO563 AOS29719.1     1
 ATY49_19630   Xanthomonas oryzae pv. oryzae PXO602 AOS33863.1     1
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