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Glycoside Hydrolase Family 5 / Subf 1

Activities in Sub FamilyEndo-β-1,4-glucanase (EC 3.2.1.4);
Lichenase / endo-β-1,3-1,4-glucanase (EC 3.2.1.73);
Exo-β-1,4-glucanase / cellodextrinase (EC 3.2.1.74);
Mechanism Retaining e
ClanGH-A
3D Structure Status( β / α ) 8 barrel
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental)
NoteOnce known as cellulase family A; many members have been assigned to subfamilies as described by Aspeborg et al. (2012) BMC Evol Biol. 12(1):186 (PMID: 22992189).
External resourcesCAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; NZYTech; PROZOMIX;
Statistics GenBank accession (59); Uniprot accession (38); PDB accession (16); 3D entries (4); cryst (0)
Summary
Download GH5_1 (1573) Taxonomic display Structure (4) Characterized (37)
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | ... | 15 |
Bacteria
Protein Name EC#Organism GenBankUniprotPDB/3DSubf
 LHJ49_15550   Clavibacter michiganensis subsp. michiganensis CMM84 UDM12234.1     1
 PSS89_12690 (fragment)   Clavibacter michiganensis subsp. michiganensis Cmm_21 WDD27940.1     1
 PSS89_15525   Clavibacter michiganensis subsp. michiganensis Cmm_21 WDD30030.1     1
 CelA (fragment)   Clavibacter michiganensis subsp. michiganensis Cmm_MKH AEM65927.1
AEM65928.1		     1
 GRD74_15765   Clavibacter michiganensis subsp. michiganensis MSF322 QIT13040.1     1
 endo-1,4-β-glycosidase, partial (CelA) (fragment)   Clavibacter michiganensis subsp. michiganensis MSF322 QYU76384.1     1
 endo-1,4-β-glycosidase, partial (CelB) (fragment)   Clavibacter michiganensis subsp. michiganensis MSF322 QYU76393.1     1
 MU580_12950   Clavibacter michiganensis subsp. michiganensis N.P. UOW03165.1     1
 CMM_2443 (CelB)   Clavibacter michiganensis subsp. michiganensis NCPPB 382 CAN02524.1     1
 bifunctional cellulase / expansin (CelA;pCM1_0020) 3.2.1.4 Clavibacter michiganensis subsp. michiganensis NCPPB 382 CAA44467.2
CAM98473.1		 A5CLK3
Q9K5C7		   1
 endo-1,4-β-glycosidase, partial (CelB) (fragment)   Clavibacter michiganensis subsp. michiganensis OP3 QYU76398.1     1
 endo-1,4-β-glycosidase, partial (CelA) (fragment)   Clavibacter michiganensis subsp. michiganensis OP3 QYU76389.1     1
 endo-1,4-β-glycosidase, partial (CelA) (fragment)   Clavibacter michiganensis subsp. michiganensis OP7 QYU76390.1     1
 endo-1,4-β-glycosidase, partial (CelB) (fragment)   Clavibacter michiganensis subsp. michiganensis OP7 QYU76399.1     1
 EFE39_15410   Clavibacter michiganensis subsp. michiganensis UF1 QGV76751.1     1
 endo-1,4-β-glycosidase, partial (CelA) (fragment)   Clavibacter michiganensis subsp. michiganensis VL368 QYU76385.1     1
 endo-1,4-β-glycosidase, partial (CelB) (fragment)   Clavibacter michiganensis subsp. michiganensis VL368 QYU76394.1     1
 GRD61_16045   Clavibacter michiganensis subsp. michiganensis VL527 QIT16217.1
QYU76387.1		     1
 GRD61_12870   Clavibacter michiganensis subsp. michiganensis VL527 QIT15432.1
QYU76396.1		     1
 endo-1,4-β-glycosidase, partial (CelA) (fragment)   Clavibacter michiganensis subsp. michiganensis VL542 QYU76388.1     1
 endo-1,4-β-glycosidase, partial (CelB) (fragment)   Clavibacter michiganensis subsp. michiganensis VL542 QYU76397.1     1
 endo-1,4-β-glycosidase, partial (CelB) (fragment)   Clavibacter michiganensis subsp. michiganensis VQ143 QYU76392.1     1
 KN200_15915   Clavibacter michiganensis subsp. michiganensis VQ28 QXP07556.1     1
 endo-1,4-β-glycosidase, partial (CelB) (fragment)   Clavibacter michiganensis subsp. michiganensis VQ28 QYU76391.1     1
 endo-1,4-β-glycosidase, partial (CelA) (fragment)   Clavibacter michiganensis subsp. michiganensis VQ28 QYU76383.1     1
 endo-1,4-β-glycosidase, partial (CelA) (fragment)   Clavibacter michiganensis subsp. michiganensis VQ519 QYU76386.1     1
 endo-1,4-β-glycosidase, partial (CelB) (fragment)   Clavibacter michiganensis subsp. michiganensis VQ519 QYU76395.1     1
 WDV94_00710   Clavibacter michiganensis subsp. tessellarius ARGTr 8-1 WXZ50307.1     1
 FGG90_08370   Clavibacter michiganensis subsp. tessellarius ATCC 33566 UKF34016.1     1
 LIX20_002396   Clavibacter nebraskensis 419B UQB13027.1     1
 LIX22_002395   Clavibacter nebraskensis 44 UQB15862.1     1
 EGX35_11885   Clavibacter nebraskensis 61-1 QGV73059.1     1
 EGX37_11885   Clavibacter nebraskensis 7580 QGV70268.1     1
 FGQ65_12460   Clavibacter nebraskensis A6096 UKF28935.1     1
 LIX19_002386   Clavibacter nebraskensis CIBA UQB10191.1     1
 LIV34_002383   Clavibacter nebraskensis CNK-2 UQB04538.1     1
 EGX36_11930   Clavibacter nebraskensis HF4 QGV67468.1     1
 CMN_02390 (CeL)   Clavibacter nebraskensis NCPPB 2581 CCE76326.1     1
 LIX21_002384   Clavibacter nebraskensis SL1 UQB09295.1     1
 cellulase (CelA;pCS0061) 3.2.1.4 Clavibacter sepedonicus ATCC 33113 AAK16222.1
CAQ03244.1		 B0RJ54
Q9AF65		   1
 LRE50_16125   Clavibacter sepedonicus K496 UUK67285.1     1
 KYT88_12615   Clavibacter sp. A6099 UKF24556.1     1
 CAC0912   Clostridium acetobutylicum ATCC 824 AAK78888.1
NP_347548.1		     1
 SMB_G0929 (CelB)   Clostridium acetobutylicum DSM 1731 AEI33087.1     1
 CEA_G0924   Clostridium acetobutylicum EA 2018 ADZ19963.1     1
 DK921_10960   Clostridium acetobutylicum LJ4 AWV80607.1     1
 CLAUR_014390   Clostridium aurantibutyricum DSM 793 URZ01444.1     1
 endoglucanase (Eng5A)   Clostridium cellulovorans BAV13030.1     1
 endoglucanase (Eng5E)   Clostridium cellulovorans BAV13035.1     1
 Clocel_0619   Clostridium cellulovorans 743B ADL50390.1     1
 Clocel_0983   Clostridium cellulovorans 743B ADL50749.1     1
 CLFE_015450   Clostridium felsineum DSM 794 URZ15505.1     1
 psyc5s11_39200   Clostridium gelidum C5S11 BCZ47853.1     1
 CLROS_010380   Clostridium roseum DSM 6424 URZ05712.1     1
 CROST_014610   Clostridium roseum DSM 7320 URZ10751.1     1
 Cspa_c18680 (Celb2)   Clostridium saccharoperbutylacetonicum N1-4(HMT) AGF55638.1     1
 Clo1100_1829   Clostridium sp. BNL1100 AEY66039.1     1
 Clo1100_2788   Clostridium sp. BNL1100 AEY66946.1     1
 B5808_07170   Cnuibacter physcomitrellae XA(T) ARJ05010.1     1
 HH215_30930   Cohnella herbarum MFER-1 QJD87157.1     1
 Cwoe_0159   Conexibacter woesei DSM 14684 ADB48595.1     1
 COUCH_17025   Couchioplanes caeruleus TL65 UQU67872.1     1
 PA27867_1437   Cryobacterium arcticum PAMC 27867 ANP72394.1     1
 KIV56_18125   Cryobacterium breve ERMR7:08 WBM80028.1     1
 KY500_05295   Cryobacterium sp. PAMC25264 QYF74598.1     1
 BJQ94_07665   Cryobacterium sp. SO2 WEO78902.1     1
 SAY89_14410   Cyanobacterium aponinum AL20115 WPF87976.1     1
 WEU38_14340   Cyanobacterium aponinum AL20118 WXZ61317.1     1
 Cyan10605_2560   Cyanobacterium aponinum PCC 10605 AFZ54640.1     1
 VKI22_10535   Cyanobacterium aponinum UTEX 3221 WRL37066.1     1
 VKI21_07025   Cyanobacterium aponinum UTEX 3222 WRL43429.1     1
 F0U63_23490   Cystobacter fuscus Cbf 10 WNG17301.1     1
 F0U62_24680   Cystobacter fuscus Cbf 8 WNG26858.1     1
 CYFUS_005260   Cystobacter fuscus DSM 52655 ATB39812.1     1
 Daura_40990   Dactylosporangium aurantiacum NRRL B-8018 UWZ52917.1     1
 Daura_15205   Dactylosporangium aurantiacum NRRL B-8018 UWZ57380.1     1
 Dfulv_37130   Dactylosporangium fulvum NRRL B-16292 UWP80729.1     1
 Dmats_36980   Dactylosporangium matsuzakiense NRRL B-16293 UWZ43050.1     1
 Dmats_29045   Dactylosporangium matsuzakiense NRRL B-16293 UWZ41678.1     1
 Dmats_37390   Dactylosporangium matsuzakiense NRRL B-16293 UWZ49999.1     1
 Drose_27885   Dactylosporangium roseum NRRL B-16295 UWZ34965.1     1
 KZZ52_38235   Dactylosporangium sp. AC04546 WVK89702.1     1
 KZZ52_48435   Dactylosporangium sp. AC04546 WVK81720.1     1
 GCM10020063_016720   Dactylosporangium thailandense JCM 3084 BFE57146.1     1
 GCM10020063_110020   Dactylosporangium thailandense JCM 3084 BFE66476.1     1
 GCM10020063_046610   Dactylosporangium thailandense JCM 3084 BFE60135.1     1
 Dvina_42295   Dactylosporangium vinaceum NRRL B-16297 UAB94680.1     1
 Dvina_34205   Dactylosporangium vinaceum NRRL B-16297 UAB93299.1     1
 Dvina_42715   Dactylosporangium vinaceum NRRL B-16297 UAC02240.1     1
 LGT36_002620   Demequina sp. TMPB413 UPU88830.1     1
 QUF31_21385 (fragment)   Dickeya chrysanthemi BRR1 WJM85514.1     1
 N7L95_22305   Eleftheria terrae P9846-PB WKB52498.1     1
 EUS_18130   [Eubacterium] siraeum 70/3 CBK96886.1     1
 NQ549_08305   [Eubacterium] siraeum DSM 15702 UWP24534.1     1
 ES1_23790   [Eubacterium] siraeum V10Sc8a CBL35203.1     1
 KP625_02410   Eubacterium sp. MSJ-33 QWT53501.1     1
 C1H87_01040   Flavivirga eckloniae ECD14 AUP77378.1     1
 cellulase GH5   Flavobacterium sp. AUG42 QCD26736.1     1
 SAMN04488543_1663   Friedmanniella luteola DSM 21741 SDS40102.1     1
 LVD16_27190   Fulvivirga ligni W9P-11 UII21517.1     1
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