Glycoside Hydrolase Family 5 / Subf 1

Activities in Familyendo-β-1,4-glucanase / cellulase (EC 3.2.1.4); endo-β-1,4-xylanase (EC 3.2.1.8); β-glucosidase (EC 3.2.1.21); β-mannosidase (EC 3.2.1.25); β-glucosylceramidase (EC 3.2.1.45); glucan β-1,3-glucosidase (EC 3.2.1.58); licheninase (EC 3.2.1.73); exo-β-1,4-glucanase / cellodextrinase (EC 3.2.1.74); glucan endo-1,6-β-glucosidase (EC 3.2.1.75); mannan endo-β-1,4-mannosidase (EC 3.2.1.78); cellulose β-1,4-cellobiosidase (EC 3.2.1.91); steryl β-glucosidase (EC 3.2.1.104); endoglycoceramidase (EC 3.2.1.123); chitosanase (EC 3.2.1.132); β-primeverosidase (EC 3.2.1.149); xyloglucan-specific endo-β-1,4-glucanase (EC 3.2.1.151); endo-β-1,6-galactanase (EC 3.2.1.164); hesperidin 6-O-α-L-rhamnosyl-β-glucosidase (EC 3.2.1.168); β-1,3-mannanase (EC 3.2.1.-); arabinoxylan-specific endo-β-1,4-xylanase (EC 3.2.1.-); mannan transglycosylase (EC 2.4.1.-)
Activities in Sub Family
Mechanism Retaining
ClanGH-A
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental)
NoteOnce known as cellulase family A; many members have been assigned to subfamilies as described by Aspeborg et al. (2012) BMC Evol Biol. 12(1):186 (PMID: 22992189).
External resourcesCAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; NZYTech; PROZOMIX;
Statistics GenBank accession (610); Uniprot accession (102); PDB accession (15); 3D entries (3); cryst (0)
| 1 | 2 | 3 | 4 | 5 | 6 |
Bacteria
Protein Name EC#Organism GenBankUniprotPDB/3DSubf
 RD2015_749   Roseateles depolymerans KCTC 42856 ALV05245.1     1
 RGI145_02340   Roseomonas gilardii U14-5 APT56123.1     1
 CMCase (P66;Ccel_2337) 3.2.1.4 Ruminiclostridium cellulolyticum H10 ACL76673.1 B8I5D7   1
 cellulase N (CelN; Ccel_0740) (Cel5N) 3.2.1.4 Ruminiclostridium cellulolyticum H10 ACL75118.1
AAG45162.1
B8I7W1
Q9EYQ0
  1
 Cel5B (Cel5B)   Ruminiclostridium josui BAI52933.1 D1MXA2   1
 Rumal_1049   Ruminococcus albus 7 = DSM 20455 ADU21575.1 E0L9A2   1
 Rumal_2017   Ruminococcus albus 7 = DSM 20455 ADU22510.1 E0LAT0   1
 Rumal_2777   Ruminococcus albus 7 = DSM 20455 ADU23246.1 E0L654   1
 cellulase (Cel5G)   Ruminococcus albus 8 AAT48117.1 Q6GVN1   1
 lichenase (Ra2830;CUS_5609) 3.2.1.73 Ruminococcus albus 8 EGC04285.1
ZP_08157835.1
    1
 RBI_I00497   Ruminococcus bicirculans 80/3 CCO04221.1     1
 endo-β-1,4-glucanase (GH5B;RUM_06330) (Cel5B) 3.2.1.4 Ruminococcus champanellensis 18P13 = JCM 17042 CBL16847.1 D4LB52   1
 Strop_2684   Salinispora tropica CNB-440 ABP55128.1 A4X8C8   1
 SAMD00079811_23510   Scytonema sp. HK-05 NIES-2130 BAY44749.1     1
 SAMD00079811_39570   Scytonema sp. HK-05 NIES-2130 BAY46348.1     1
 NIES4073_72930   Scytonema sp. NIES-4073 BAZ26387.1     1
 NIES4073_56600   Scytonema sp. NIES-4073 BAZ24761.1     1
 SVI_0875   Shewanella violacea DSS12 BAJ00846.1 D4ZGP7   1
 M5M_14915   Simiduia agarivorans SA1 = DSM 21679 AFV00118.1
AFV00107.2
    1
 STHERM_c20620 (StX;StCBM64A) 3.2.1.4 Spirochaeta thermophila DSM 6192 ADN02996.1 E0RQU0   1
 Spith_2109   Spirochaeta thermophila DSM 6578 AEJ62365.1     1
 C7M71_023240   Streptacidiphilus sp. DSM 106435 AXI79881.1     1
 DMT42_17410   Streptomyces actuosus ATCC 25421 AWT43919.1     1
 BV401_21515   Streptomyces autolyticus CGMCC0516 AQA12639.1     1
 SBI_05889   Streptomyces bingchenggensis BCW-1 ADI09009.1 D7CGA5   1
 DWG14_04720   Streptomyces griseorubiginosus 3E-1 AYC40455.1     1
 SHXM_05206   Streptomyces hygroscopicus XM201 AQW51743.1     1
 SIRAN5394   Streptomyces iranensis CDR08747.1     1
 SLCG_3059   Streptomyces lincolnensis LC-G AXG54214.1     1
 SLCG_3059   Streptomyces lincolnensis LC-G AXG54214.1     1
 SLINC_3798   Streptomyces lincolnensis NRRL 2936 ANS66022.1     1
 SMALA_3611   Streptomyces malaysiensis DSM 4137 ATL83845.1     1
 SNOD_15095   Streptomyces nodosus ATCC 14899 AJE41211.1     1
 Sfla_0913   Streptomyces pratensis ATCC 33331 ADW02371.1 C9NB23   1
 A4E84_17785   Streptomyces qaidamensis S10(2016) AMW11190.1     1
 M271_26970   Streptomyces rapamycinicus NRRL 5491 AGP56864.1     1
 A4G23_00273   Streptomyces rubrolavendulae MJM4426 AOT57484.1     1
 SCAB_51081   Streptomyces scabiei 87.22 CBG72151.1 C9YTK2   1
 CGL27_22625   Streptomyces sp. 11-1-2 ASQ95494.1     1
 SAMN05444521_4982   Streptomyces sp. 3214.6 SHI18454.1     1
 AS200_25685   Streptomyces sp. CdTB01 ALV35061.1     1
 C1703_17145   Streptomyces sp. Go-475 AXE86734.1     1
 CFP59_05028   Streptomyces sp. M56 AUA12875.1     1
 C6376_11910   Streptomyces sp. P3 AVV42024.1     1
 F750_5941   Streptomyces sp. PAMC 26508 AGJ58369.1     1
 B9S64_28810   Streptomyces sp. SM18 AWL41642.1     1
 Strvi_8930   Streptomyces violaceusniger Tu 4113 AEM88231.1     1
 DKM19_02670   Streptosporangium sp. caverna AWS40401.1     1
 SCL_1792   Sulfuricaulis limicola HA5 BAV34090.1     1
 TJEJU_3612   Tenacibaculum jejuense KCTC 22618 SNR17255.1     1
 TERTU_3565   Teredinibacter turnerae T7901 ACR11017.1 C5BRI4   1
 endoglucanase (EGtf2) (Cel5B) 3.2.1.4 Thermobifida fusca TM51 AAP56348.1 Q7X2N2   1
 endoglucanase 5B (Tfu_2712) (Cel5B) 3.2.1.4 Thermobifida fusca YX AAZ56745.1 Q47LC7   1
 multidomain cellulase   thermophilic anaerobe NA10 BAA22939.1 O24820   1
 endocellulase (CelA) (Cel5A) 3.2.1.4 Thermus caldophilus GK24 AAK60011.1 Q93Q07   1
 TCCBUS3UF1_1700   Thermus sp. CCB_US3_UF1 AEV15219.1     1
 Trad_1441   Truepera radiovictrix DSM 17093 ADI14563.1 D7CX55   1
 CelE2, partial   uncultured bacterium ANN44164.1     1
 VAB18032_22475   Verrucosispora maris AB-18-032 AEB45595.1     1
 XALc_2967   Xanthomonas albilineans GPE PC73 CBA17444.1     1
 XALc_2969   Xanthomonas albilineans GPE PC73 CBA17446.1     1
 AKJ12_08070   Xanthomonas arboricola pv. juglandis Xaj 417 AKU49746.1     1
 XACM_0615 (EngxcA)   Xanthomonas axonopodis pv. citrumelo F1 AEO40920.1     1
 XAC29_03125   Xanthomonas axonopodis Xac29-1 AGH76155.1     1
 XB05_20710   Xanthomonas campestris 17 AKC80882.1     1
 endo-β-1,4-glucanase (EngXCA;EngA) (frameshift) 3.2.1.4 Xanthomonas campestris pv. campestris CAC18529.1
AAA27612.1
Q9EVR6 4TUF[A,B,C,D] 1
 AAW18_17365   Xanthomonas campestris pv. campestris 17 ALE70057.1     1
 AEA01_03155   Xanthomonas campestris pv. campestris 4013 AKS19035.1     1
 AEA00_03125   Xanthomonas campestris pv. campestris ICMP 21080 AKS15008.1     1
 XC_0639   Xanthomonas campestris pv. campestris str. 8004 AAY47719.1 Q4UZ04   1
 endo-β-1,4-glucanase (EngXCA;XccEG;XCC3521) 3.2.1.4 Xanthomonas campestris pv. campestris str. ATCC 33913 AAM42791.1
NP_638867.1
P19487   1
 xcc-b100_0675 (EngXCA)   Xanthomonas campestris pv. campestris str. B100 CAP50014.1 P19487   1
 XCR_3859 (EngXCA)   Xanthomonas campestris pv. raphani 756C AEL08719.1     1
 XCV0670 (EngXCA)   Xanthomonas campestris pv. vesicatoria str. 85-10 CAJ22301.1
AOY68300.1
Q3BXW2   1
 AC028_09270   Xanthomonas citri pv. aurantifolii 1566 AMV06963.1     1
 TP45_02600   Xanthomonas citri pv. aurantifolii FDC 1561 ARE55338.1     1
 CLM98_03770   Xanthomonas citri pv. citri 03-1638-1-1 AUZ49783.1     1
 J152_00729   Xanthomonas citri pv. citri 5208 AJZ38424.1     1
 J165_03949   Xanthomonas citri pv. citri AW13 AJZ46035.1     1
 J166_03953   Xanthomonas citri pv. citri AW14 AJZ50654.1     1
 J167_03954   Xanthomonas citri pv. citri AW15 AJZ55275.1     1
 J168_03950   Xanthomonas citri pv. citri AW16 AJZ68066.1     1
 J170_00725   Xanthomonas citri pv. citri BL18 AJZ33955.1     1
 J171_00727   Xanthomonas citri pv. citri FB19 AJZ29492.1     1
 J154_00733   Xanthomonas citri pv. citri gd2 AJZ25074.1     1
 J155_00733   Xanthomonas citri pv. citri gd3 AJZ20648.1     1
 AB890_03190   Xanthomonas citri pv. citri jx-6 AKM23858.1     1
 J156_00734   Xanthomonas citri pv. citri jx4 AJZ16225.1     1
 J157_00734   Xanthomonas citri pv. citri jx5 AJZ11796.1     1
 BJD09_13295   Xanthomonas citri pv. citri LH201 APR25044.1     1
 BI316_04650   Xanthomonas citri pv. citri LH276 APR18926.1     1
 BI315_16605   Xanthomonas citri pv. citri LJ207-7 APR16186.1     1
 BI314_21610   Xanthomonas citri pv. citri LL074-4 APR12374.1     1
 J172_00726   Xanthomonas citri pv. citri mf20 AJZ07325.1     1
 J162_00731   Xanthomonas citri pv. citri MN10 AJZ02902.1     1
 J163_00731   Xanthomonas citri pv. citri MN11 AJY98478.1     1
 J164_00731   Xanthomonas citri pv. citri MN12 AJY94054.1     1
 J169_00731   Xanthomonas citri pv. citri NT17 AJY89583.1     1
 XAC0612 (EngXCA)   Xanthomonas citri pv. citri str. 306 AAM35501.1
NP_640965.1
Q8PPS3   1
 B7L65_20635   Xanthomonas citri pv. citri TX160042 ARR19057.1     1
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