Glycoside Hydrolase Family 5

Activities in Familyendo-β-1,4-glucanase / cellulase (EC 3.2.1.4); endo-β-1,4-xylanase (EC 3.2.1.8); β-glucosidase (EC 3.2.1.21); β-mannosidase (EC 3.2.1.25); β-glucosylceramidase (EC 3.2.1.45); glucan β-1,3-glucosidase (EC 3.2.1.58); licheninase (EC 3.2.1.73); exo-β-1,4-glucanase / cellodextrinase (EC 3.2.1.74); glucan endo-1,6-β-glucosidase (EC 3.2.1.75); mannan endo-β-1,4-mannosidase (EC 3.2.1.78); cellulose β-1,4-cellobiosidase (EC 3.2.1.91); steryl β-glucosidase (EC 3.2.1.104); endoglycoceramidase (EC 3.2.1.123); chitosanase (EC 3.2.1.132); β-primeverosidase (EC 3.2.1.149); xyloglucan-specific endo-β-1,4-glucanase (EC 3.2.1.151); endo-β-1,6-galactanase (EC 3.2.1.164); hesperidin 6-O-α-L-rhamnosyl-β-glucosidase (EC 3.2.1.168); β-1,3-mannanase (EC 3.2.1.-); arabinoxylan-specific endo-β-1,4-xylanase (EC 3.2.1.-); mannan transglycosylase (EC 2.4.1.-)
Mechanism Retaining
ClanGH-A
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental)
NoteOnce known as cellulase family A; many members have been assigned to subfamilies as described by Aspeborg et al. (2012) BMC Evol Biol. 12(1):186 (PMID: 22992189).
External resourcesCAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; NZYTech; PROZOMIX;
Statistics GenBank accession (14323); Uniprot accession (1922); PDB accession (218); 3D entries (77); cryst (0)
All (12930) Archaea (94) Bacteria (10492) Eukaryota (2215) Viruses (8) unclassified (121) Structure (77) Characterized (551)
| 1 | ... | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | ... | 105 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D Subf
 A3L20_18535   Bacillus thuringiensis HD12 AMR88058.1     48
 AC241_17265   Bacillus thuringiensis HS18-1 AKR12420.1     48
 endo-β-1,4-glucanase (fragment)   Bacillus thuringiensis IARI-SP-6 AGW99983.1     2
 BCM43_11585   Bacillus thuringiensis KNU-07 ANV74005.1     48
 B4918_19610   Bacillus thuringiensis L-7601 AQY42210.1     48
 CUC43_32110   Bacillus thuringiensis LM1212 AXY11283.1     28
 MC28_G027   Bacillus thuringiensis MC28 AFU17760.1     48
 BT246_38300 (fragment)   Bacillus thuringiensis MYBT18246 ANS49178.1     48
 BT246_63680 (fragment)   Bacillus thuringiensis MYBT18246 ANS51660.1     48
 BT246_66980 (fragment)   Bacillus thuringiensis MYBT18246 ANS51990.1     48
 D7J84_21585   Bacillus thuringiensis QZL38 AYF84711.1     48
 Bt4C1_17180   Bacillus thuringiensis serovar alesti BGSC 4C1 AND10926.1     48
 CT43_CH3456   Bacillus thuringiensis serovar chinensis CT-43 AEA17123.1     48
 A9498_18185   Bacillus thuringiensis serovar coreanensis ST7 ANN35388.1     48
 BT4G5_29985 (fragment)   Bacillus thuringiensis serovar galleriae HD-29 AJA23074.1     48
 BT4G5_18355   Bacillus thuringiensis serovar galleriae HD-29 AJA22935.1     48
 NF53_3388   Bacillus thuringiensis serovar indiana HD521 AKR36466.1     48
 ATN07_17345   Bacillus thuringiensis serovar israelensis AM65-52 AND27454.1     48
 BG08_2313   Bacillus thuringiensis serovar kurstaki HD 1 AJK42767.1     48
 BTK_18640   Bacillus thuringiensis serovar kurstaki str. HD-1 AIE34780.1     48
 HD73_3790   Bacillus thuringiensis serovar kurstaki str. HD73 AGE79368.1     48
 DF16_orf02442 (BglC)   Bacillus thuringiensis serovar kurstaki str. YBT-1520 AIM30857.1     48
 YBT1520_18690   Bacillus thuringiensis serovar kurstaki str. YBT-1520 AHZ52363.1     48
 SD98_18215   Bacillus thuringiensis serovar morrisoni BGSC 4AA1 AJQ62320.1     48
 H175_ch3513   Bacillus thuringiensis serovar thuringiensis str. IS5056 AGG02225.1     48
 BG07_1333   Bacillus thuringiensis str. Al Hakam AJI15237.1     48
 BG07_59 (fragment)   Bacillus thuringiensis str. Al Hakam AJI17850.1     48
 YBT1518_19285   Bacillus thuringiensis YBT-1518 AHA72997.1     48
 XI92_25155   Bacillus thuringiensis YC-10 AKJ62307.1     48
 BVH75_15275   Bacillus thuringiensis YGD22-03 ARX69947.1     48
 BVH75_30260   Bacillus thuringiensis YGD22-03 ARX70213.1     28
 AQ980_12375   Bacillus thuringiensis YWC2-8 ALL61887.1     48
 B9C48_09240   Bacillus vallismortis NBIF-001 ARM28000.1     2
 C0W57_06835   Bacillus velezensis 10075 AUS15916.1     2
 CFN60_09420   Bacillus velezensis 157 ASK58591.1     2
 EG882_14895   Bacillus velezensis 1B-23 AZJ44488.1     2
 BK055_10270   Bacillus velezensis 9912D APA02899.1     2
 B7941_11800   Bacillus velezensis 9D-6 ARJ75167.1     2
 endoglucanase, partial (EglS)   Bacillus velezensis A4 AYO51733.1     2
 RZ52_09125   Bacillus velezensis AP183 AWK46308.1     2
 B938_09365   Bacillus velezensis AS43.3 AFZ90893.1     2
 BMJ37_09290   Bacillus velezensis ATR2 ATU26929.1     2
 BAMMD1_1755 (EglS)   Bacillus velezensis B25 CUX93659.1     2
 EG219_08725   Bacillus velezensis BCSo1 AZG39173.1     2
 D3C60_09205   Bacillus velezensis BIM B-439D AXY37919.1     2
 CMR26_07555   Bacillus velezensis BS-37 AWG38431.1     2
 BACAU_1766 (BglC)   Bacillus velezensis CAU B946 CCF05300.1     2
 BCBMB205_18710   Bacillus velezensis CBMB205 ANF36769.1
ARN87289.1
    2
 A1D33_000185   Bacillus velezensis CC09 ANB45748.1     2
 C3Z10_09765   Bacillus velezensis CGMCC 11640 AVI28645.1     2
 CVD07_09175   Bacillus velezensis CN026 ATY28447.1     2
 A2I97_08780   Bacillus velezensis D2-2 AOU01160.1     2
 DA376_09390   Bacillus velezensis DR-08 AVV94124.1     2
 BVDSYZ_09785   Bacillus velezensis DSYZ AWX72297.1     2
 RBAM_018100   Bacillus velezensis FZB42 CAE11243.1
ABS74173.1
    2
 ABH13_1848   Bacillus velezensis G341 AKL76432.1     2
 B6257_19060   Bacillus velezensis GFP-2 AUJ62547.1     2
 BAGQ_1973   Bacillus velezensis GQJK49 ARZ58207.1     2
 B9C53_00960   Bacillus velezensis GYL4 AWD12147.1     2
 B7L90_08260   Bacillus velezensis Hx05 AWM83213.1     2
 CJP14_07175   Bacillus velezensis J01 ASZ03660.1     2
 AAV29_08940   Bacillus velezensis JJ-D34 AKF30670.1     2
 NG74_01886 (EglS)   Bacillus velezensis JS25R AIU81966.1     2
 BAJT_09240   Bacillus velezensis JTYP2 ARB33457.1     2
 CRH11_14675   Bacillus velezensis L-1 ATO11163.1     2
 CQJ38_09320   Bacillus velezensis LABIM40 ATL39711.1     2
 DDE72_07450   Bacillus velezensis LM23DO2 AWE16031.1     2
 A8142_08875   Bacillus velezensis LS69 ANU30279.1     2
 CXP43_10450   Bacillus velezensis Lzh-a42 AUG36120.1     2
 BBJ33_09410   Bacillus velezensis M75 AOO61741.1     2
 BVMH_09535   Bacillus velezensis MH25 AZI47122.1     2
 BAPNAU_1934 (BglC)   Bacillus velezensis NAU-B3 CDH95715.1     2
 AW02_018440 (BglC)   Bacillus velezensis NJN-6 AKD29994.1     2
 EEB07_19455   Bacillus velezensis NY12-2 AYV19409.1     2
 D0U03_09300   Bacillus velezensis OSY-GA1 AXT12600.1     2
 alkali tolerable endoglucanase, partial (Ega5)   Bacillus velezensis Q5 ALE32753.1     2
 BVQ_09580   Bacillus velezensis QST713 AWD87699.1     2
 endoglucanase (EglS)   Bacillus velezensis RS1 AUB45040.1     2
 BVS141_18850 (EglS)   Bacillus velezensis S141 BBA76409.1     2
 A5891_09010   Bacillus velezensis S3-1 ANS38519.1     2
 CHN56_00337 (EglS)   Bacillus velezensis SCDB 291 ASS60881.1     2
 CLI97_03910 (EglS)   Bacillus velezensis SCGB 1 ATC53134.1     2
 CLI98_03744 (EglS)   Bacillus velezensis SCGB 574 ATD76966.1     2
 C1N92_00760   Bacillus velezensis SGAir0473 AWQ13510.1     2
 V529_17790 (BglC)   Bacillus velezensis SQR9 AHZ15805.1     2
 S100072_01973   Bacillus velezensis SRCM100072 ASB53309.1     2
 S101413_02134   Bacillus velezensis SRCM101413 ASB65581.1     2
 BLL65_09625   Bacillus velezensis sx01604 AQZ73217.1     2
 CEG11_09415   Bacillus velezensis T20E-257 ASF55305.1     2
 CG798_14945   Bacillus velezensis TB1501 ASP26388.1     2
 AJ82_10290   Bacillus velezensis TrigoCor1448 AHK49356.1     2
 RBAU_1784 (EglS)   Bacillus velezensis UCMB5033 CDG29752.1     2
 BAM5036_1746 (EglS)   Bacillus velezensis UCMB5036 CCP21786.1     2
 BASU_1764 (EglS)   Bacillus velezensis UCMB5113 CDG26057.1     2
 C6P48_09830   Bacillus velezensis VCC-2003 AVM08503.1     2
 BANAU_1935 (BglC)   Bacillus velezensis YAU B9601-Y2 CCG49956.1     2
 AAV30_10320   Bacillus velezensis YJ11-1-4 AKF76524.1     2
 D3N19_09300   Bacillus velezensis ZF2 AXY70422.1     2
 BK049_00270   Bacillus xiamenensis VV3 AOZ87243.1     7
 cellulase   bacterium enrichment culture AJO67866.1     4
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