| Activities in Family | [retaining] arabinoxylan-specific endo-β-1,4-xylanase (EC 3.2.1.-); β-1,3-mannanase (EC 3.2.1.-); β-rutinosidase /α-L-rhamnose-(1,6)-β-D-glucosidase (EC 3.2.1.-); Glucomannan-specific endo-β-1,4-glucanase (EC 3.2.1.-); Exo-β-1,4-mannobiohydrolase / mannobiose-producing exo-β-mannanase (EC 3.2.1.100); Steryl β-glucosidase (EC 3.2.1.104); Endoglycosylceramidase (EC 3.2.1.123); Chitosanase (EC 3.2.1.132); β-D-galactofuranosidase (EC 3.2.1.146); β-primeverosidase (EC 3.2.1.149); Oligoxyloglucan reducing-end-specific cellobiohydrolase (EC 3.2.1.150); Xyloglucan-specific endo-β-1,4-glucanase / endo-xyloglucanase (EC 3.2.1.151); Endo-β-1,6-galactanase (EC 3.2.1.164); Hesperidin 6-O-α-L-rhamnosyl-β-glucosidase (EC 3.2.1.168); β-glucosidase (EC 3.2.1.21); β-galactosidase (EC 3.2.1.23); β-mannosidase (EC 3.2.1.25); Xylan β-1,4-xylosidase (EC 3.2.1.37); Endo-β-1,3-glucanase / laminarinase (EC 3.2.1.39); Endo-β-1,4-glucanase (EC 3.2.1.4); β-glucosylceramidase (EC 3.2.1.45); β-galactosylceramidase (EC 3.2.1.46); β-N-acetylhexosaminidase (EC 3.2.1.52); α-L-arabinofuranosidase (EC 3.2.1.55); Exo-β-1,3-glucanase (EC 3.2.1.58); Endo-β-1,3(4)-glucanase / lichenase-laminarinase (EC 3.2.1.6); Lichenase / endo-β-1,3-1,4-glucanase (EC 3.2.1.73); Exo-β-1,4-glucanase / cellodextrinase (EC 3.2.1.74); Endo-β-1,6-glucanase (EC 3.2.1.75); Endo-β-1,4-mannanase (EC 3.2.1.78); Endo-β-1,4-xylanase (EC 3.2.1.8); Cellobiohydrolase (EC 3.2.1.91); |
|---|---|
| Mechanism | Retaining e |
| Clan | GH-A |
| 3D Structure Status | ( β / α ) 8 barrel |
| Catalytic Nucleophile/Base | Glu (experimental) |
| Catalytic Proton Donor | Glu (experimental) |
| Note | Once known as cellulase family A; many members have been assigned to subfamilies as described by Aspeborg et al. (2012) BMC Evol Biol. 12(1):186 (PMID: 22992189). |
| External resources | CAZypedia; HOMSTRAD; PROSITE; |
| Commercial Enzyme Provider(s) | MEGAZYME; NZYTech; PROZOMIX; |
| Statistics | GenBank accession (29905); Uniprot accession (671); PDB accession (290); 3D entries (107); cryst (0) |