Activities in Sub Family	Endo-β-1,4-mannanase (EC 3.2.1.78);
Mechanism	Retaining e
Clan	GH-A
3D Structure Status	( β / α ) 8 barrel
Catalytic Nucleophile/Base	Glu (experimental)
Catalytic Proton Donor	Glu (experimental)
Note	Once known as cellulase family A; many members have been assigned to subfamilies as described by Aspeborg et al. (2012) BMC Evol Biol. 12(1):186 (PMID: 22992189).
External resources	CAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)	MEGAZYME; NZYTech; PROZOMIX;
Statistics	GenBank accession (10); Uniprot accession (37); PDB accession (10); 3D entries (6); cryst (0)

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Bacteria
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D	Subf
HG421_07270		Xanthomonas campestris pv. badrii NEB122	QJD67539.1			8
JH298_11935		Xanthomonas campestris pv. campestris 0474	WDJ71058.1			8
JH278_10035		Xanthomonas campestris pv. campestris 0659	WDJ70281.1			8
JH257_10040		Xanthomonas campestris pv. campestris 0792	WDJ61876.1			8
JH266_10040		Xanthomonas campestris pv. campestris 0793	WDJ66081.1			8
JH306_12025		Xanthomonas campestris pv. campestris 08284	WDJ54310.1			8
JH309_12480		Xanthomonas campestris pv. campestris 08288	WDJ79451.1			8
JH256_12485		Xanthomonas campestris pv. campestris 08290	WDJ33120.1			8
JH275_12035		Xanthomonas campestris pv. campestris 08305	WDK04832.1			8
JH265_12265		Xanthomonas campestris pv. campestris 10006	WDK43956.1			8
JH312_12260		Xanthomonas campestris pv. campestris 10008	WDK39652.1			8
JH310_12320		Xanthomonas campestris pv. campestris 10090	WDJ37251.1			8
JH282_12390		Xanthomonas campestris pv. campestris 10103	WDJ75266.1			8
JH304_12270		Xanthomonas campestris pv. campestris 10108	WDJ28865.1			8
JH300_12315		Xanthomonas campestris pv. campestris 11085	WDK34158.1			8
JH293_12070		Xanthomonas campestris pv. campestris 12049	WDJ49957.1			8
JH286_11990		Xanthomonas campestris pv. campestris 12112	WDJ45656.1			8
JH313_12030		Xanthomonas campestris pv. campestris 13108G	WDJ41465.1			8
JH296_12135		Xanthomonas campestris pv. campestris 15-1	WDK77563.1			8
AAW18_08870		Xanthomonas campestris pv. campestris 17	ALE68568.1			8
JH294_09325		Xanthomonas campestris pv. campestris 25-4	WDK76654.1			8
JH284_08515		Xanthomonas campestris pv. campestris 27-10	WDK72451.1			8
JH258_09325		Xanthomonas campestris pv. campestris 27-6	WDK68577.1			8
JH271_09315		Xanthomonas campestris pv. campestris 27-9	WDK64533.1			8
JH301_12100		Xanthomonas campestris pv. campestris 28-1	WDK56555.1			8
JH291_20025		Xanthomonas campestris pv. campestris 29-5	WDL46162.1			8
JH292_12175		Xanthomonas campestris pv. campestris 29-6	WDL40803.1			8
JH303_09900		Xanthomonas campestris pv. campestris 30-1	WDL60404.1			8
JH288_12465		Xanthomonas campestris pv. campestris 33-1	WDL36723.1			8
JH255_11890		Xanthomonas campestris pv. campestris 33-2	WDL32513.1			8
JH297_09975		Xanthomonas campestris pv. campestris 33-4	WDL31758.1			8
JH276_11845		Xanthomonas campestris pv. campestris 33-5	WDL24337.1			8
JH263_09260		Xanthomonas campestris pv. campestris 39-3	WDL56120.1			8
JH287_07380		Xanthomonas campestris pv. campestris 40-2	WDL51737.1			8
AEA01_11715		Xanthomonas campestris pv. campestris 4013	AKS20523.1			8
JH289_09650		Xanthomonas campestris pv. campestris 42-1	WDK93061.1			8
JH305_09610		Xanthomonas campestris pv. campestris 42-2	WDK88919.1			8
JH268_09960		Xanthomonas campestris pv. campestris 42-3	WDL23581.1			8
JH311_12080		Xanthomonas campestris pv. campestris 42-4	WDK81527.1			8
JH269_11985		Xanthomonas campestris pv. campestris 54-2	WDL65346.1			8
JH259_12540		Xanthomonas campestris pv. campestris 54-3	WDL61273.1			8
JH267_12605		Xanthomonas campestris pv. campestris 55-1	WDK52446.1			8
JH308_08545		Xanthomonas campestris pv. campestris 55-2	WDK51307.1			8
JH285_09910		Xanthomonas campestris pv. campestris 66-2	WDL19499.1			8
JM952_12285		Xanthomonas campestris pv. campestris BJSJQ20200612	UKA38723.1			8
QJS49_12690		Xanthomonas campestris pv. campestris CFBP 9145	WMB23532.1			8
JH272_12585		Xanthomonas campestris pv. campestris CFBP12825	WDJ12587.1			8
JH281_17870		Xanthomonas campestris pv. campestris CFBP6943	WDI85054.1			8
KJQ95_13040		Xanthomonas campestris pv. campestris GBBC 1073	UQB63167.1			8
KIV67_12065		Xanthomonas campestris pv. campestris GBBC1458	UPS16154.1			8
JOA57_12025		Xanthomonas campestris pv. campestris GSXT20191014	UKA42961.1			8
AEA00_11550		Xanthomonas campestris pv. campestris ICMP 21080	AKS16497.1			8
Xcc1_24450		Xanthomonas campestris pv. campestris MAFF106712	BBJ96715.1			8
Xcc3_24540		Xanthomonas campestris pv. campestris MAFF302021	BBK01147.1			8
LR085_12390		Xanthomonas campestris pv. campestris SB80	UIU01585.1			8
endo-β-1,4-mannanase (ManA;XC_2458)		Xanthomonas campestris pv. campestris str. 8004	AAY49508.1			8
endo-β-1,4-mannosidase (ManA;XCC1778)	3.2.1.78	Xanthomonas campestris pv. campestris str. ATCC 33913	AAM41068.1 NP_637144.1	Q8P9S0		8
xcc-b100_2486 (ManA)		Xanthomonas campestris pv. campestris str. B100	CAP51846.1			8
VDP59_012325		Xanthomonas campestris pv. campestris WHRI 6066	WVJ82961.1			8
VDR56_012390		Xanthomonas campestris pv. campestris WHRI 8978	WWD73293.1			8
KPR34_12855		Xanthomonas campestris pv. campestris Xcc-C7	QXJ15569.1			8
DFG55_17710		Xanthomonas campestris pv. campestris Xcc8004_Xcc1	QCX68005.1			8
DFG54_12715		Xanthomonas campestris pv. campestris Xcc8004_Xcc2	QCX71498.1			8
OF401_11975		Xanthomonas campestris pv. campestris XY1-1	UYP76290.1			8
JH274_11660		Xanthomonas campestris pv. incanae 16-8	WDK24026.1			8
JH290_09605		Xanthomonas campestris pv. incanae 18048	UAU36343.1			8
JH260_09355		Xanthomonas campestris pv. incanae 4053	WDJ95584.1			8
JH262_11880		Xanthomonas campestris pv. incanae 5057	WDJ96381.1			8
JH279_09935		Xanthomonas campestris pv. incanae 8-14	WDJ86855.1			8
JH295_12330		Xanthomonas campestris pv. incanae CFBP1606	WDI96271.1			8
JH261_11980		Xanthomonas campestris pv. incanae CFBP6690	WDJ04605.1			8
NCPPB1935_13790		Xanthomonas campestris pv. nigromaculans NCPPB 1935	CAH2708822.1			8
JH283_11945		Xanthomonas campestris pv. raphani 5055	WDI88166.1			8
JH277_11750		Xanthomonas campestris pv. raphani 576	WDJ24903.1			8
JH270_12855		Xanthomonas campestris pv. raphani 609	WDJ20809.1			8
JH264_09125		Xanthomonas campestris pv. raphani 719	WDJ19815.1			8
XCR_2021		Xanthomonas campestris pv. raphani 756C	AEL06909.1			8
AD14011_11880		Xanthomonas campestris pv. raphani MAFF106181	QLC70143.1			8
DGM98_10030		Xanthomonas citri M11	QWN20433.1			8
AC028_16915		Xanthomonas citri pv. aurantifolii 1566	AMV08302.1			8
β-mannanase (XcGH5_8; TP37_09655)	3.2.1.78	Xanthomonas citri pv. aurantifolii FDC 1559	AMU98328.1			8
TP45_10335		Xanthomonas citri pv. aurantifolii FDC 1561	ARE56697.1			8
TP50_13060		Xanthomonas citri pv. aurantifolii FDC 1609	AMV03262.1			8
CLM98_10025		Xanthomonas citri pv. citri 03-1638-1-1	AUZ50854.1			8
J152_01948		Xanthomonas citri pv. citri 5208	AJZ39612.1			8
J165_02617		Xanthomonas citri pv. citri AW13	AJZ44727.1			8
J166_02619		Xanthomonas citri pv. citri AW14	AJZ49344.1			8
J167_02618		Xanthomonas citri pv. citri AW15	AJZ53963.1			8
J168_02618		Xanthomonas citri pv. citri AW16	AJZ66758.1			8
HZS92_01921		Xanthomonas citri pv. citri B2	QYF39849.1			8
J170_01943		Xanthomonas citri pv. citri BL18	AJZ35142.1			8
XCQ_09120		Xanthomonas citri pv. citri CQ13	UPS79496.1			8
H8Z73_09175		Xanthomonas citri pv. citri DAR72029	QRD66336.1			8
H8Z71_12495		Xanthomonas citri pv. citri DAR73886	QRD72238.1			8
H8Z72_13230		Xanthomonas citri pv. citri DAR73889	QRD67735.1			8
H8Z74_09205		Xanthomonas citri pv. citri DAR73909	QRD61834.1			8
H8Z75_05105		Xanthomonas citri pv. citri DAR73910	QRD56929.1			8
H8Z70_12605		Xanthomonas citri pv. citri DAR84832	QRD76633.1			8
J171_01945		Xanthomonas citri pv. citri FB19	AJZ30679.1			8
J154_01942		Xanthomonas citri pv. citri gd2	AJZ26252.1			8
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