Glycoside Hydrolase Family 13

Activities in Familyα-amylase (EC 3.2.1.1); pullulanase (EC 3.2.1.41); cyclomaltodextrin glucanotransferase (EC 2.4.1.19); cyclomaltodextrinase (EC 3.2.1.54); trehalose-6-phosphate hydrolase (EC 3.2.1.93); oligo-α-glucosidase (EC 3.2.1.10); maltogenic amylase (EC 3.2.1.133); neopullulanase (EC 3.2.1.135); α-glucosidase (EC 3.2.1.20); maltotetraose-forming α-amylase (EC 3.2.1.60); isoamylase (EC 3.2.1.68); glucodextranase (EC 3.2.1.70); maltohexaose-forming α-amylase (EC 3.2.1.98); maltotriose-forming α-amylase (EC 3.2.1.116); branching enzyme (EC 2.4.1.18); trehalose synthase (EC 5.4.99.16); 4-α-glucanotransferase (EC 2.4.1.25); maltopentaose-forming α-amylase (EC 3.2.1.-) ; amylosucrase (EC 2.4.1.4) ; sucrose phosphorylase (EC 2.4.1.7); malto-oligosyltrehalose trehalohydrolase (EC 3.2.1.141); isomaltulose synthase (EC 5.4.99.11); malto-oligosyltrehalose synthase (EC 5.4.99.15); amylo-α-1,6-glucosidase (EC 3.2.1.33); α-1,4-glucan: phosphate α-maltosyltransferase (EC 2.4.99.16); 6'-P-sucrose phosphorylase (EC 2.4.1.-); amino acid transporter
Mechanism Retaining
ClanGH-H
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseAsp (experimental)
Catalytic Proton DonorGlu (experimental)
NoteNew: many members have been assigned to subfamilies as described by Stam et al. (2006) Protein Eng Des Sel. 19, 555-562 (PMID: 17085431)
External resourcesCAZypedia; EBI Protein of the Month; HOMSTRAD; PDB Molecule of the Month; PRINTS;
Commercial Enzyme Provider(s)MEGAZYME; PROZOMIX;
Statistics GenBank accession (63317); Uniprot accession (7865); PDB accession (486); 3D entries (114); cryst (2)
All (58438) Archaea (382) Bacteria (54614) Eukaryota (3312) unclassified (130) Structure (114 - 2 cryst) Characterized (815)
| 1 | ... | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | ... | 34 |
Eukaryota
Protein Name EC#OrganismGenBank UniprotPDB/3D Subf
 CG33138 protein, partial (fragment)   Drosophila albomicans X108 BAR88905.1     8
 amylase-related protein (Amyrel) (fragment)   Drosophila ambigua AAN16193.1     15
 α-amylase (Amy) (fragment)   Drosophila ambigua ECOSSE AAN16140.1     15
 Amyrel (fragment)   Drosophila americana AAW66434.1     15
 maltase 1 (Mav1) (fragment)   Drosophila americana 15010-0951.0 AAP12720.1 Q86FU8  
 Amyrel (fragment)   Drosophila americana texana AAW66445.1     15
 α-amylase 38/58 (Amy;Amy35;Amy58;AmyTBU118)   Drosophila ananassae AAC79123.1
AAC47353.1
AAC79122.1
BAA22481.1
O15947
O18345
Q23835
  15
 α-amylase 4N (Amy4N)   Drosophila ananassae AAC48343.1
AAC47352.1
Q23834   15
 α-amylase C1 3.2.1.1 Drosophila ananassae AAC35243.1 O77407   15
 amylase C1 (fragment)   Drosophila ananassae AAC47354.1 Q23836  
 Amy C6 (Amyrel)   Drosophila ananassae AAC39090.3 O18344   15
 Amyrel (fragment)   Drosophila angularis AAW66435.1     15
 putative amylase (fragment)   Drosophila aracataca AAC47372.1 Q23837  
 Amyrel   Drosophila aracataca AAW64455.1     15
 alpha amylase-related-protein, partial (AmyreL) (fragment)   Drosophila aracataca 15040-1171.00 AHL43632.1     15
 alpha amylase, partial (fragment)   Drosophila aracataca 15040-1171.00 AHL43644.1     15
 Amyrel (fragment)   Drosophila aracea AAW66436.1     15
 Amyrel   Drosophila ararama AAW64451.1     15
 Amyrel   Drosophila arawakana AAO84660.1 Q86N69   15
 Amy (fragment)   Drosophila arawakana AAQ13446.1 Q5NKY1   15
 amylase-related protein, partial (AmyreL) (fragment)   Drosophila arizonae AJP07832.1     15
 Amyrel   Drosophila asahinai AAL99575.1 Q8T7Y0   15
 α-amylase (Amy) (fragment)   Drosophila athabasca AAN16149.1     15
 α-amylase (Amy) (fragment)   Drosophila athabasca AAN16150.1 Q71V28   15
 amylase-related protein (Amyrel) (fragment)   Drosophila athabasca AAN16196.1     15
 amylase, partial (fragment)   Drosophila athabasca AVP37704.1    
 amylase, partial (fragment)   Drosophila athabasca AVP37683.1    
 amylase, partial (fragment)   Drosophila athabasca AVP37711.1    
 amylase, partial (fragment)   Drosophila athabasca AVP37756.1    
 amylase, partial (fragment)   Drosophila athabasca AVP37745.1    
 amylase, partial (fragment)   Drosophila athabasca AVP37732.1    
 amylase, partial (fragment)   Drosophila athabasca AVP37723.1    
 amylase, partial (fragment)   Drosophila athabasca AVP37693.1    
 amylase, partial (fragment)   Drosophila athabasca AVP37749.1    
 amylase, partial (fragment)   Drosophila athabasca AVP37762.1    
 amylase, partial (fragment)   Drosophila athabasca AVP37734.1    
 amylase, partial (fragment)   Drosophila athabasca AVP37727.1    
 amylase, partial (fragment)   Drosophila athabasca AVP37775.1    
 amylase, partial (fragment)   Drosophila athabasca AVP37709.1    
 amylase, partial (fragment)   Drosophila athabasca AVP37783.1    
 amylase, partial (fragment)   Drosophila athabasca AVP37706.1    
 amylase, partial (fragment)   Drosophila athabasca AVP37695.1    
 amylase, partial (fragment)   Drosophila athabasca AVP37687.1    
 amylase, partial (fragment)   Drosophila athabasca AVP37725.1    
 amylase, partial (fragment)   Drosophila athabasca AVP37701.1    
 amylase, partial (fragment)   Drosophila athabasca AVP37760.1    
 amylase, partial (fragment)   Drosophila athabasca AVP37685.1    
 amylase, partial (fragment)   Drosophila athabasca AVP37785.1    
 amylase, partial (fragment)   Drosophila athabasca AVP37771.1    
 amylase, partial (fragment)   Drosophila athabasca AVP37747.1    
 amylase, partial (fragment)   Drosophila athabasca AVP37707.1    
 amylase, partial (fragment)   Drosophila athabasca AVP37773.1    
 amylase, partial (fragment)   Drosophila athabasca AVP37788.1    
 amylase, partial (fragment)   Drosophila athabasca AVP37703.1    
 amylase, partial (fragment)   Drosophila athabasca AVP37714.1    
 amylase, partial (fragment)   Drosophila athabasca AVP37719.1    
 amylase, partial (fragment)   Drosophila athabasca AVP37754.1    
 amylase, partial (fragment)   Drosophila athabasca AVP37726.1    
 amylase, partial (fragment)   Drosophila athabasca AVP37780.1    
 amylase, partial (fragment)   Drosophila athabasca AVP37689.1    
 amylase, partial (fragment)   Drosophila athabasca AVP37739.1    
 amylase, partial (fragment)   Drosophila athabasca AVP37731.1    
 amylase, partial (fragment)   Drosophila athabasca AVP37782.1    
 amylase, partial (fragment)   Drosophila athabasca AVP37769.1    
 amylase, partial (fragment)   Drosophila athabasca AVP37790.1    
 amylase, partial (fragment)   Drosophila athabasca AVP37721.1    
 amylase, partial (fragment)   Drosophila athabasca AVP37691.1    
 amylase, partial (fragment)   Drosophila athabasca AVP37752.1    
 amylase, partial (fragment)   Drosophila athabasca AVP37741.1    
 amylase, partial (fragment)   Drosophila athabasca AVP37712.1    
 amylase, partial (fragment)   Drosophila athabasca AVP37764.1    
 amylase, partial (fragment)   Drosophila athabasca AVP37743.1    
 amylase, partial (fragment)   Drosophila athabasca AVP37767.1    
 amylase, partial (fragment)   Drosophila athabasca AVP37757.1    
 amylase, partial (fragment)   Drosophila athabasca AVP37778.1    
 amylase, partial (fragment)   Drosophila athabasca AVP37729.1    
 amylase, partial (fragment)   Drosophila athabasca AVP37776.1    
 amylase, partial (fragment)   Drosophila athabasca AVP37705.1    
 amylase, partial (fragment)   Drosophila athabasca AVP37736.1    
 amylase, partial (fragment)   Drosophila athabasca AVP37761.1    
 amylase, partial (fragment)   Drosophila athabasca AVP37733.1    
 amylase, partial (fragment)   Drosophila athabasca AVP37698.1    
 amylase, partial (fragment)   Drosophila athabasca AVP37774.1    
 amylase, partial (fragment)   Drosophila athabasca AVP37710.1    
 amylase, partial (fragment)   Drosophila athabasca AVP37777.1    
 amylase, partial (fragment)   Drosophila athabasca AVP37786.1    
 amylase, partial (fragment)   Drosophila athabasca AVP37750.1    
 amylase, partial (fragment)   Drosophila athabasca AVP37744.1    
 amylase, partial (fragment)   Drosophila athabasca AVP37722.1    
 amylase, partial (fragment)   Drosophila athabasca AVP37692.1    
 amylase, partial (fragment)   Drosophila athabasca AVP37770.1    
 amylase, partial (fragment)   Drosophila athabasca AVP37766.1    
 amylase, partial (fragment)   Drosophila athabasca AVP37708.1    
 amylase, partial (fragment)   Drosophila athabasca AVP37759.1    
 amylase, partial (fragment)   Drosophila athabasca AVP37746.1    
 amylase, partial (fragment)   Drosophila athabasca AVP37737.1    
 amylase, partial (fragment)   Drosophila athabasca AVP37724.1    
 amylase, partial (fragment)   Drosophila athabasca AVP37784.1    
 amylase, partial (fragment)   Drosophila athabasca AVP37772.1    
 amylase, partial (fragment)   Drosophila athabasca AVP37694.1    
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