Glycoside Hydrolase Family 13

Activities in Familyα-amylase (EC 3.2.1.1); pullulanase (EC 3.2.1.41); cyclomaltodextrin glucanotransferase (EC 2.4.1.19); cyclomaltodextrinase (EC 3.2.1.54); trehalose-6-phosphate hydrolase (EC 3.2.1.93); oligo-α-glucosidase (EC 3.2.1.10); maltogenic amylase (EC 3.2.1.133); neopullulanase (EC 3.2.1.135); α-glucosidase (EC 3.2.1.20); maltotetraose-forming α-amylase (EC 3.2.1.60); isoamylase (EC 3.2.1.68); glucodextranase (EC 3.2.1.70); maltohexaose-forming α-amylase (EC 3.2.1.98); maltotriose-forming α-amylase (EC 3.2.1.116); branching enzyme (EC 2.4.1.18); trehalose synthase (EC 5.4.99.16); 4-α-glucanotransferase (EC 2.4.1.25); maltopentaose-forming α-amylase (EC 3.2.1.-) ; amylosucrase (EC 2.4.1.4) ; sucrose phosphorylase (EC 2.4.1.7); malto-oligosyltrehalose trehalohydrolase (EC 3.2.1.141); isomaltulose synthase (EC 5.4.99.11); malto-oligosyltrehalose synthase (EC 5.4.99.15); amylo-α-1,6-glucosidase (EC 3.2.1.33); α-1,4-glucan: phosphate α-maltosyltransferase (EC 2.4.99.16); amino acid transporter; [retaining] sucrose 6(F)-phosphate phosphorylase (EC 2.4.1.329); [retaining] glucosylglycerol phosphorylase (EC 2.4.1.359); ; Glucosylglycerate phosphorylase (EC 2.4.1.352); [retaining] sucrose α-glucosidase (EC 3.2.1.48); oligosaccharide α-4-glucosyltransferase (EC 2.4.1.161); [retaining] α-amylase (EC 3.2.1.1)
Mechanism Retaining
ClanGH-H
3D Structure Status( β / α ) 8 barrel
Catalytic Nucleophile/BaseAsp (experimental)
Catalytic Proton DonorGlu (experimental)
NoteNew: many members have been assigned to subfamilies as described by Stam et al. (2006) Protein Eng Des Sel. 19, 555-562 (PMID: 17085431)
External resourcesCAZypedia; EBI Protein of the Month; HOMSTRAD; PDB Molecule of the Month; PRINTS;
Commercial Enzyme Provider(s)MEGAZYME; PROZOMIX;
Statistics GenBank accession (121044); Uniprot accession (7841); PDB accession (589); 3D entries (140); cryst (2)
All (115994) Archaea (642) Bacteria (110564) Eukaryota (4654) Viruses (3) unclassified (131) Structure (140 - 2 cryst) Characterized (824)
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | ... | 47 |
Eukaryota
Protein Name EC#OrganismGenBank UniprotPDB/3D Subf
 α-amylase (fragment)   Acanthochitona fascicularis ACA34373.1 D2YVN1  
 α-amylase (fragment)   Acanthochitona fascicularis ACA34376.1 D2YVN4  
 α-amylase (fragment)   Acanthochitona fascicularis ACA34378.1 D2YVN6  
 α-amylase (fragment)   Acanthochitona fascicularis ACA34382.1 D2YVP0  
 α-amylase (fragment)   Acanthochitona fascicularis ACA34384.1 D2YVP2  
 α-amylase (fragment)   Acanthochitona fascicularis ACA34385.1 D2YVP3  
 α-amylase 2, partial (AmY) (fragment)   Acanthochitona sp. AEA72219.1    
 AmY (fragment)   Acanthochitona sp. JLDL-2011 AEA72218.1    
 α-amylase / allergen (Aca s 4) 3.2.1.1 Acarus siro ABL09312.1 B0KZK1   24
 secreted protein   Achlya hypogyna ATCC 48635 AIG56379.1    
 secreted protein   Achlya hypogyna ATCC 48635 AIG56379.1     1
 α-amylase (plastid) (Amy3)   Actinidia chinensis AFO84072.1
AAX33233.1
CAW95501.1
CAX01336.1
CAX06581.1
CAX06912.1
CBD14454.1
Q5BLY1   6
 α-amylase (Amy1)   Actinidia chinensis AFO84070.1     6
 α-amylase (Amy2)   Actinidia chinensis AFO84071.1     6
 ISA2   Actinidia deliciosa AOQ26242.1    
 ISA1   Actinidia deliciosa AOQ26241.1     11
 ISA3   Actinidia deliciosa AOQ26243.1     11
 PUL1   Actinidia deliciosa AOQ26240.1     13
 sucrase / α-glucosidase (S1;APS1) 3.2.1.20 Acyrthosiphon pisum ABB55878.1 Q0H3F1   17
 ACYPI004887 (fragment)   Acyrthosiphon pisum LSR1 BAH72207.1 C4WWD7   8
 ACYPI000002 (fragment)   Acyrthosiphon pisum LSR1 BAH72291.1 C4WWM1   17
 α-amylase (amy) (fragment)   Aedes aegypti AAA03321.1 Q16901  
 α-amylase I (AmyI)   Aedes aegypti AAA29343.1
AAA29344.1
AAA29345.1
AAB60935.1
O02413
P53354
  15
 α-amylase II (AmyII)   Aedes aegypti AAB60934.1 O02652   15
 α-glucosidase (Mal1;MalI; AAEL009524-PA)   Aedes aegypti AAA29352.1
AAA29351.1
ABM68601.1
ACC76784.1
ACC76785.1
ACC76786.1
CBF79241.1
P13080   17
 α-glucosidase (Aam1;AaeL_AAEL010537)   Aedes aegypti Liverpool XP_001660909.1     17
 ORF   Aedes albopictus AAV90637.1
CAZ78874.1
Q5MIZ5   17
 α-amylase   Aedes atropalpus AAA03322.1 Q16924   15
 isoamylase   Aegilops tauschii AAP44579.1 Q7XA16   11
 Sequence 6 from patent US 6916976   Aegilops tauschii ABA16971.1     8
 Sequence 12 from patent US 6916976   Aegilops tauschii ABA16972.1     8
 Sequence 71 from patent US 6916976   Aegilops tauschii ABA16992.1     8
 starch branching enzyme IIb (SBE II-DB1) (fragments)   Aegilops tauschii AAW80632.1
AAW80633.1
Q24M32   8
 SBE-I   Aegilops tauschii subsp. strangulata AAD30187.1 Q6KFU0   8
 starch branching enzyme II   Agave tequilana QED40919.1     8
 alpha amylase a3   Agave tequilana QED40920.1     6
 isoamylase   Agave tequilana QEU57406.1     11
 starch branching enzyme (SbE)   Amaranthus caudatus BAR73032.1     8
 starch branching enzyme (SbE)   Amaranthus hybridus subsp. cruentus BAR73033.1     8
 isoamylase1-type starch debranching enzyme (Dbe1;DBE)   Amaranthus hybridus subsp. cruentus BAP91163.1     11
 isoamylase-type starch debranching enzyme 3 (Isa3;CrISA3) 3.2.1.68 Amaranthus hybridus subsp. cruentus BAQ22171.1     11
 starch branching enzyme (SbE)   Amaranthus hypochondriacus BAR73034.1     8
 ORF   Amblyomma maculatum AEO34594.1    
 ORF   Amblyomma maculatum AEO36080.1     8
 ORF (fragment)   Amblyomma maculatum AEO32115.1     24
 α-amylase (fragment)   Amphipholis squamata ACA34390.1 D2YVP8  
 CB5_LOCUS17129 (fragment)   Ananas comosus var. bracteatus VUW66544.1
CAB5268819.1
    8
 CB5_LOCUS13408   Ananas comosus var. bracteatus VUW62827.1
CAB5265102.1
    6
 CB5_LOCUS17126 (fragment)   Ananas comosus var. bracteatus VUW66541.1
CAB5268816.1
    8
 CB5_LOCUS14551   Ananas comosus var. bracteatus VUW63968.1
CAB5266243.1
    6
 CB5_LOCUS21534   Ananas comosus var. bracteatus VUW70949.1
CAB5273224.1
    13
 CB5_LOCUS6193 (fragment)   Ananas comosus var. bracteatus VUW55616.1
CAB5257891.1
    11
 CB5_LOCUS8044 (fragment)   Ananas comosus var. bracteatus VUW57466.1
CAB5259741.1
    6
 CB5_LOCUS9670 (fragment)   Ananas comosus var. bracteatus VUW59091.1
CAB5261366.1
    8
 CB5_LOCUS7401   Ananas comosus var. bracteatus VUW56823.1
CAB5259098.1
    11
 CB5_LOCUS6194 (fragment)   Ananas comosus var. bracteatus VUW55617.1
CAB5257892.1
    11
 CB5_LOCUS1240   Ananas comosus var. bracteatus VUW50664.1
CAB5252939.1
    8
 CB5_LOCUS1515   Ananas comosus var. bracteatus CAD1818304.1     8
 CB5_LOCUS21743   Ananas comosus var. bracteatus CAD1838532.1     8
 CB5_LOCUS4473 (fragment)   Ananas comosus var. bracteatus CAD1821262.1     8
 CB5_LOCUS19938 (fragment)   Ananas comosus var. bracteatus CAD1836727.1     8
 CB5_LOCUS4426 (fragment)   Ananas comosus var. bracteatus CAD1821215.1     8
 CB5_LOCUS27142   Ananas comosus var. bracteatus CAD1843931.1     13
 CB5_LOCUS27220   Ananas comosus var. bracteatus CAD1844009.1     13
 CB5_LOCUS21748 (fragment)   Ananas comosus var. bracteatus CAD1838537.1     8
 CB5_LOCUS27141 (fragment)   Ananas comosus var. bracteatus CAD1843930.1     3
 CB5_LOCUS18403   Ananas comosus var. bracteatus CAD1835192.1     6
 CB5_LOCUS10297 (fragment)   Ananas comosus var. bracteatus CAD1827086.1     6
 CB5_LOCUS12466 (fragment)   Ananas comosus var. bracteatus CAD1829255.1     8
 CB5_LOCUS12449 (fragment)   Ananas comosus var. bracteatus CAD1829238.1     11
 CB5_LOCUS10226 (fragment)   Ananas comosus var. bracteatus CAD1827015.1     6
 CB5_LOCUS7965 (fragment)   Ananas comosus var. bracteatus CAD1824754.1     11
 CB5_LOCUS17120   Ananas comosus var. bracteatus CAD1833909.1     6
 CB5_LOCUS9528   Ananas comosus var. bracteatus CAD1826317.1     11
 CB5_LOCUS8096   Ananas comosus var. bracteatus CAD1824885.1     11
 CB5_LOCUS10227 (fragment)   Ananas comosus var. bracteatus CAD1827016.1     6
 α-amylase, partial (fragment)   Anastrepha fraterculus AVO65462.1     15
 α-amylase, partial (fragment)   Anastrepha fraterculus AVO65454.1     15
 α-amylase, partial (fragment)   Anastrepha fraterculus AVO65438.1     15
 α-amylase, partial (fragment)   Anastrepha fraterculus AVO65450.1     15
 α-amylase, partial (fragment)   Anastrepha fraterculus AVO65434.1     15
 α-amylase, partial (fragment)   Anastrepha fraterculus AVO65455.1     15
 α-amylase, partial (fragment)   Anastrepha fraterculus AVO65459.1     15
 α-amylase, partial (fragment)   Anastrepha fraterculus AVO65437.1     15
 α-amylase, partial (fragment)   Anastrepha fraterculus AVO65451.1     15
 α-amylase, partial (fragment)   Anastrepha fraterculus AVO65456.1     15
 α-amylase, partial (fragment)   Anastrepha fraterculus AVO65463.1     15
 α-amylase, partial (fragment)   Anastrepha fraterculus AVO65452.1     15
 α-amylase, partial (fragment)   Anastrepha fraterculus AVO65460.1     15
 α-amylase, partial (fragment)   Anastrepha fraterculus AVO65457.1     15
 α-amylase, partial (fragment)   Anastrepha fraterculus AVO65464.1     15
 α-amylase, partial (fragment)   Anastrepha fraterculus AVO65461.1     15
 α-amylase, partial (fragment)   Anastrepha fraterculus AVO65453.1     15
 α-amylase, partial (fragment)   Anastrepha fraterculus AVO65435.1     15
 α-amylase, partial (fragment)   Anastrepha fraterculus AVO65458.1     15
 α-amylase, partial (fragment)   Anastrepha fraterculus AVO65436.1     15
 α-amylase, partial (fragment)   Anastrepha fraterculus AVO65449.1     15
 α-amylase, partial (fragment)   Anastrepha obliqua AVO65469.1     15
 α-amylase, partial (fragment)   Anastrepha obliqua AVO65481.1     15
 α-amylase, partial (fragment)   Anastrepha obliqua AVO65477.1     15
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