Glycoside Hydrolase Family 13

Activities in Familyα-amylase (EC 3.2.1.1); pullulanase (EC 3.2.1.41); cyclomaltodextrin glucanotransferase (EC 2.4.1.19); cyclomaltodextrinase (EC 3.2.1.54); trehalose-6-phosphate hydrolase (EC 3.2.1.93); oligo-α-glucosidase (EC 3.2.1.10); maltogenic amylase (EC 3.2.1.133); neopullulanase (EC 3.2.1.135); α-glucosidase (EC 3.2.1.20); maltotetraose-forming α-amylase (EC 3.2.1.60); isoamylase (EC 3.2.1.68); glucodextranase (EC 3.2.1.70); maltohexaose-forming α-amylase (EC 3.2.1.98); maltotriose-forming α-amylase (EC 3.2.1.116); branching enzyme (EC 2.4.1.18); trehalose synthase (EC 5.4.99.16); 4-α-glucanotransferase (EC 2.4.1.25); maltopentaose-forming α-amylase (EC 3.2.1.-) ; amylosucrase (EC 2.4.1.4) ; sucrose phosphorylase (EC 2.4.1.7); malto-oligosyltrehalose trehalohydrolase (EC 3.2.1.141); isomaltulose synthase (EC 5.4.99.11); malto-oligosyltrehalose synthase (EC 5.4.99.15); amylo-α-1,6-glucosidase (EC 3.2.1.33); α-1,4-glucan: phosphate α-maltosyltransferase (EC 2.4.99.16); 6'-P-sucrose phosphorylase (EC 2.4.1.-); amino acid transporter
Mechanism Retaining
ClanGH-H
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseAsp (experimental)
Catalytic Proton DonorGlu (experimental)
NoteNew: many members have been assigned to subfamilies as described by Stam et al. (2006) Protein Eng Des Sel. 19, 555-562 (PMID: 17085431)
External resourcesCAZypedia; EBI Protein of the Month; HOMSTRAD; PDB Molecule of the Month; PRINTS;
Commercial Enzyme Provider(s)MEGAZYME; PROZOMIX;
Statistics GenBank accession (66285); Uniprot accession (7872); PDB accession (486); 3D entries (114); cryst (2)
All (61404) Archaea (391) Bacteria (57550) Eukaryota (3337) unclassified (126) Structure (114 - 2 cryst) Characterized (815)
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | ... | 34 |
Eukaryota
Protein Name EC#OrganismGenBank UniprotPDB/3D Subf
 α-amylase (fragment)   Acanthochitona fascicularis ACA34373.1 D2YVN1  
 α-amylase (fragment)   Acanthochitona fascicularis ACA34376.1 D2YVN4  
 α-amylase (fragment)   Acanthochitona fascicularis ACA34378.1 D2YVN6  
 α-amylase (fragment)   Acanthochitona fascicularis ACA34382.1 D2YVP0  
 α-amylase (fragment)   Acanthochitona fascicularis ACA34384.1 D2YVP2  
 α-amylase (fragment)   Acanthochitona fascicularis ACA34385.1 D2YVP3  
 α-amylase 2, partial (AmY) (fragment)   Acanthochitona sp. AEA72219.1    
 AmY (fragment)   Acanthochitona sp. JLDL-2011 AEA72218.1    
 α-amylase / allergen (Aca s 4) 3.2.1.1 Acarus siro ABL09312.1 B0KZK1   24
 secreted protein   Achlya hypogyna ATCC 48635 AIG56379.1    
 secreted protein   Achlya hypogyna ATCC 48635 AIG56379.1     1
 α-amylase (plastid) (Amy3)   Actinidia chinensis AFO84072.1
AAX33233.1
CAW95501.1
CAX01336.1
CAX06581.1
CAX06912.1
CBD14454.1
Q5BLY1   6
 α-amylase (Amy1)   Actinidia chinensis AFO84070.1     6
 α-amylase (Amy2)   Actinidia chinensis AFO84071.1     6
 ISA2   Actinidia deliciosa AOQ26242.1    
 ISA1   Actinidia deliciosa AOQ26241.1     11
 ISA3   Actinidia deliciosa AOQ26243.1     11
 PUL1   Actinidia deliciosa AOQ26240.1     13
 sucrase / α-glucosidase (S1;APS1) 3.2.1.20 Acyrthosiphon pisum ABB55878.1 Q0H3F1   17
 ACYPI004887 (fragment)   Acyrthosiphon pisum LSR1 BAH72207.1 C4WWD7   8
 ACYPI000002 (fragment)   Acyrthosiphon pisum LSR1 BAH72291.1 C4WWM1   17
 α-amylase (amy) (fragment)   Aedes aegypti AAA03321.1 Q16901  
 α-amylase I (AmyI) 3.2.1.1 Aedes aegypti AAA29343.1
AAA29344.1
AAA29345.1
AAB60935.1
O02413
P53354
  15
 α-amylase II (AmyII) 3.2.1.1 Aedes aegypti AAB60934.1 O02652   15
 α-glucosidase (Mal1;MalI; AAEL009524-PA)   Aedes aegypti AAA29352.1
AAA29351.1
ABM68601.1
ACC76784.1
ACC76785.1
ACC76786.1
CBF79241.1
P13080   17
 α-glucosidase (Aam1;AaeL_AAEL010537)   Aedes aegypti Liverpool XP_001660909.1     17
 ORF   Aedes albopictus AAV90637.1
CAZ78874.1
Q5MIZ5   17
 α-amylase 3.2.1.1 Aedes atropalpus AAA03322.1 Q16924   15
 isoamylase   Aegilops tauschii AAP44579.1 Q7XA16   11
 Sequence 6 from patent US 6916976   Aegilops tauschii ABA16971.1     8
 Sequence 12 from patent US 6916976   Aegilops tauschii ABA16972.1     8
 Sequence 71 from patent US 6916976   Aegilops tauschii ABA16992.1     8
 starch branching enzyme IIb (SBE II-DB1) (fragments)   Aegilops tauschii AAW80632.1
AAW80633.1
Q24M32   8
 SBE-I   Aegilops tauschii subsp. strangulata AAD30187.1 Q6KFU0   8
 starch branching enzyme (SbE)   Amaranthus caudatus BAR73032.1     8
 starch branching enzyme (SbE)   Amaranthus hybridus subsp. cruentus BAR73033.1     8
 isoamylase1-type starch debranching enzyme (Dbe1;DBE)   Amaranthus hybridus subsp. cruentus BAP91163.1     11
 isoamylase-type starch debranching enzyme 3 (Isa3;CrISA3) 3.2.1.68 Amaranthus hybridus subsp. cruentus BAQ22171.1     11
 starch branching enzyme (SbE)   Amaranthus hypochondriacus BAR73034.1     8
 ORF   Amblyomma maculatum AEO34594.1    
 ORF   Amblyomma maculatum AEO36080.1     8
 ORF (fragment)   Amblyomma maculatum AEO32115.1     24
 α-amylase (fragment)   Amphipholis squamata ACA34390.1 D2YVP8  
 α-amylase, partial (fragment)   Anastrepha fraterculus AVO65462.1     15
 α-amylase, partial (fragment)   Anastrepha fraterculus AVO65454.1     15
 α-amylase, partial (fragment)   Anastrepha fraterculus AVO65438.1     15
 α-amylase, partial (fragment)   Anastrepha fraterculus AVO65450.1     15
 α-amylase, partial (fragment)   Anastrepha fraterculus AVO65434.1     15
 α-amylase, partial (fragment)   Anastrepha fraterculus AVO65455.1     15
 α-amylase, partial (fragment)   Anastrepha fraterculus AVO65459.1     15
 α-amylase, partial (fragment)   Anastrepha fraterculus AVO65437.1     15
 α-amylase, partial (fragment)   Anastrepha fraterculus AVO65451.1     15
 α-amylase, partial (fragment)   Anastrepha fraterculus AVO65456.1     15
 α-amylase, partial (fragment)   Anastrepha fraterculus AVO65463.1     15
 α-amylase, partial (fragment)   Anastrepha fraterculus AVO65452.1     15
 α-amylase, partial (fragment)   Anastrepha fraterculus AVO65460.1     15
 α-amylase, partial (fragment)   Anastrepha fraterculus AVO65457.1     15
 α-amylase, partial (fragment)   Anastrepha fraterculus AVO65464.1     15
 α-amylase, partial (fragment)   Anastrepha fraterculus AVO65461.1     15
 α-amylase, partial (fragment)   Anastrepha fraterculus AVO65453.1     15
 α-amylase, partial (fragment)   Anastrepha fraterculus AVO65435.1     15
 α-amylase, partial (fragment)   Anastrepha fraterculus AVO65458.1     15
 α-amylase, partial (fragment)   Anastrepha fraterculus AVO65436.1     15
 α-amylase, partial (fragment)   Anastrepha fraterculus AVO65449.1     15
 α-amylase, partial (fragment)   Anastrepha obliqua AVO65469.1     15
 α-amylase, partial (fragment)   Anastrepha obliqua AVO65481.1     15
 α-amylase, partial (fragment)   Anastrepha obliqua AVO65477.1     15
 α-amylase, partial (fragment)   Anastrepha obliqua AVO65474.1     15
 α-amylase, partial (fragment)   Anastrepha obliqua AVO65470.1     15
 α-amylase, partial (fragment)   Anastrepha obliqua AVO65466.1     15
 α-amylase, partial (fragment)   Anastrepha obliqua AVO65478.1     15
 α-amylase, partial (fragment)   Anastrepha obliqua AVO65475.1     15
 α-amylase, partial (fragment)   Anastrepha obliqua AVO65471.1     15
 α-amylase, partial (fragment)   Anastrepha obliqua AVO65440.1     15
 α-amylase, partial (fragment)   Anastrepha obliqua AVO65467.1     15
 α-amylase, partial (fragment)   Anastrepha obliqua AVO65479.1     15
 α-amylase, partial (fragment)   Anastrepha obliqua AVO65439.1     15
 α-amylase, partial (fragment)   Anastrepha obliqua AVO65472.1     15
 α-amylase, partial (fragment)   Anastrepha obliqua AVO65482.1     15
 α-amylase, partial (fragment)   Anastrepha obliqua AVO65480.1     15
 α-amylase, partial (fragment)   Anastrepha obliqua AVO65473.1     15
 α-amylase, partial (fragment)   Anastrepha obliqua AVO65465.1     15
 α-amylase, partial (fragment)   Anastrepha obliqua AVO65468.1     15
 α-amylase, partial (fragment)   Anastrepha obliqua AVO65476.1     15
 α-amylase, partial (fragment)   Anastrepha sororcula AVO65483.1     15
 α-amylase, partial (fragment)   Anastrepha sororcula AVO65444.1     15
 α-amylase, partial (fragment)   Anastrepha sororcula AVO65487.1     15
 α-amylase, partial (fragment)   Anastrepha sororcula AVO65442.1     15
 α-amylase, partial (fragment)   Anastrepha sororcula AVO65490.1     15
 α-amylase, partial (fragment)   Anastrepha sororcula AVO65486.1     15
 α-amylase, partial (fragment)   Anastrepha sororcula AVO65491.1     15
 α-amylase, partial (fragment)   Anastrepha sororcula AVO65441.1     15
 α-amylase, partial (fragment)   Anastrepha sororcula AVO65492.1     15
 α-amylase, partial (fragment)   Anastrepha sororcula AVO65488.1     15
 α-amylase, partial (fragment)   Anastrepha sororcula AVO65448.1     15
 α-amylase, partial (fragment)   Anastrepha sororcula AVO65446.1     15
 α-amylase, partial (fragment)   Anastrepha sororcula AVO65484.1     15
 α-amylase, partial (fragment)   Anastrepha sororcula AVO65445.1     15
 α-amylase, partial (fragment)   Anastrepha sororcula AVO65489.1     15
 α-amylase, partial (fragment)   Anastrepha sororcula AVO65443.1     15
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