Glycoside Hydrolase Family 13

Activities in Familyα-amylase (EC 3.2.1.1); pullulanase (EC 3.2.1.41); cyclomaltodextrin glucanotransferase (EC 2.4.1.19); cyclomaltodextrinase (EC 3.2.1.54); trehalose-6-phosphate hydrolase (EC 3.2.1.93); oligo-α-glucosidase (EC 3.2.1.10); maltogenic amylase (EC 3.2.1.133); neopullulanase (EC 3.2.1.135); α-glucosidase (EC 3.2.1.20); maltotetraose-forming α-amylase (EC 3.2.1.60); isoamylase (EC 3.2.1.68); glucodextranase (EC 3.2.1.70); maltohexaose-forming α-amylase (EC 3.2.1.98); maltotriose-forming α-amylase (EC 3.2.1.116); branching enzyme (EC 2.4.1.18); trehalose synthase (EC 5.4.99.16); 4-α-glucanotransferase (EC 2.4.1.25); maltopentaose-forming α-amylase (EC 3.2.1.-) ; amylosucrase (EC 2.4.1.4) ; sucrose phosphorylase (EC 2.4.1.7); malto-oligosyltrehalose trehalohydrolase (EC 3.2.1.141); isomaltulose synthase (EC 5.4.99.11); malto-oligosyltrehalose synthase (EC 5.4.99.15); amylo-α-1,6-glucosidase (EC 3.2.1.33); α-1,4-glucan: phosphate α-maltosyltransferase (EC 2.4.99.16); 6'-P-sucrose phosphorylase (EC 2.4.1.-); amino acid transporter
Mechanism Retaining
ClanGH-H
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseAsp (experimental)
Catalytic Proton DonorGlu (experimental)
NoteNew: many members have been assigned to subfamilies as described by Stam et al. (2006) Protein Eng Des Sel. 19, 555-562 (PMID: 17085431)
External resourcesCAZypedia; EBI Protein of the Month; HOMSTRAD; PDB Molecule of the Month; PRINTS;
Commercial Enzyme Provider(s)MEGAZYME; PROZOMIX;
Statistics GenBank accession (57221); Uniprot accession (7858); PDB accession (471); 3D entries (111); cryst (2)
All (52442) Archaea (375) Bacteria (48858) Eukaryota (3079) unclassified (130) Structure (111 - 2 cryst) Characterized (812)
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | ... | 31 |
Eukaryota
Protein Name EC#OrganismGenBank UniprotPDB/3D Subf
 SAMEA4029009_CIC11G00000004611   [Candida] intermedia PYCC 4715 SGZ53899.1     25
 CORT_0B11040   Candida orthopsilosis Co 90-125 CCG22803.1     40
 CORT_0H02280   Candida orthopsilosis Co 90-125 CCG25338.1     8
 CORT_0B00110   Candida orthopsilosis Co 90-125 CCG21734.1     25
 CPAR2_600530   Candida parapsilosis CDC317 CCE39640.1     8
 CPAR2_109930   Candida parapsilosis CDC317 CCE40955.1     40
 CPAR2_500020   Candida parapsilosis CDC317 CCE43776.1     25
 CPAR2_400770   Candida parapsilosis CDC317 CCE44276.1     40
 glycogen branching enzyme 1, partial (Gbe1) (fragment)   Canis lupus familiaris AAY18631.1     8
 glycogen debranching enzyme (AGL)   Canis lupus familiaris ABC25005.1 Q2PQH8   25
 4F2 cell-surface antigen heavy chain (4f2hC)   Canis lupus familiaris BAO65809.1     34
 amino acid transporter SLC3A1   Canis lupus familiaris MIXED BREED AAG34759.1 Q9GKM3   35
 glycogen debranching enzyme/amylo-α-1,6-glucosidase (AgL)   Cavenderia deminutiva MexM19A AOE43284.1     25
 alpha amylase 2 (Amy2)   Cebidichthys violaceus AMQ67308.1     24
 alpha amylase 2 (Amy2)   Cebidichthys violaceus AMQ67309.1     24
 α-amylase (fragment)   Cebidichthys violaceus ABK57091.1 A0MJA3   24
 α-amylase, partial (fragment)   Centropomus undecimalis AFP86439.1    
 α-amylase (fragment)   Cerastoderma edule ACA34380.1 D2YVN8  
 starch branching enzyme I, partial (chloroplast) (fragment)   Cerasus xueluoensis AMP82277.1     8
 α-amylase (Amy)   Ceratitis capitata AAO13691.1
AAC47371.1
Q17311
Q8IA48
  15
 Amyrel   Ceratitis capitata AAO13692.1 Q8IA47   15
 α-amylase (fragment)   Ceratopteris richardii ABC87289.1 Q0QJL6   6
 α-amylase (Amy) (fragment)   Chaetonerius sp. FM-2005a AAY88823.1 Q3SCC5   15
 α-amylase (Amy) (fragment)   Chaetonerius sp. FM-2005b AAY88832.1 Q3SCB6   15
 pancreatic α-amylase (Amy2) (fragment)   Chelon labrosus CAX64421.1 C0MQV6   24
 α-amylase   Chelon labrosus AIC81809.1     24
 isoamylase 1 (Isa1;CrISA1;Sta7) 3.2.1.68 Chlamydomonas reinhardtii CC425 AAP85534.1
AAP88032.1
CAZ78881.1
Q7X8Q2 4J7R[A,B]
4OKD[A,B]
11
 Amyrel (fragment)   Chymomyza amoena AAW66449.1     15
 ORF (fragment)   Cichlasoma urophthalmum CDJ79882.1     24
 α-amylase (fragment)   Cimex lectularius ACA34377.1 D2YVN5  
 amylase, partial (fragment)   Cirrhinus cirrhosus AHY00276.1     24
 α-amylase (fragment)   Citrus reticulata AAM18229.1 Q8RW88   6
 ORF (fragment)   Citrus sinensis AFD62766.1     6
 ORF (short fragment)   Citrus sinensis AFD62767.1     6
 amylase, partial (fragment)   Clarias batrachus ART46312.1     24
 1,4-α-glucan-branching enzyme   Cocos nucifera AIC82459.1     8
 α-amylase (Amy) (fragment)   Coelopa frigida AAY88833.1 Q3SCB5   15
 α-amylase (Amy) (fragment)   Coelopa frigida AAY88834.1 Q3SCB4   15
 AmY   Colobus angolensis ABW02886.1 A8HDI0   24
 starch branching enzyme A (SbeA)   Colocasia esculenta ABP96984.1
ANC33494.1
A5HSI0   8
 ORF (fragment)   Coptotermes formosanus AGM32281.1     17
 ORF (fragment)   Coptotermes formosanus AGM32321.1     17
 ORF (fragment)   Coptotermes formosanus AGM32822.1     17
 ORF (fragment)   Coptotermes formosanus AGM32823.1     17
 α-amylase (Amy)   Corbicula fluminea AAO17927.2 Q8I9P8  
 A9K55_000120   Cordyceps militaris ATCC 34164 ATY67289.1     8
 A9K55_005467   Cordyceps militaris ATCC 34164 ATY61276.1     25
 A9K55_008949   Cordyceps militaris ATCC 34164 ATY62175.1     40
 A9K55_007977   Cordyceps militaris ATCC 34164 ATY61965.1     40
 A9K55_002235   Cordyceps militaris ATCC 34164 ATY59031.1     5
 glycogen debranching enzyme/amylo-α-1,6-glucosidase, partial (AgL)   Coremiostelium polycephalum MY1-1 AOE43286.1     25
 alpha amylase   Cosmopolites sordidus AKN63428.1     15
 ORF   Cotesia congregata CAR82255.1 B9W4L8   15
 starch branching enzyme I, partial (SbeI) (fragment)   Cotoneaster franchetii AMX81600.1     8
 starch branching enzyme I, partial (SbeI) (fragment)   Cotoneaster hebephyllus AMX81601.1     8
 starch branching enzyme I, partial (SbeI) (fragment)   Cotoneaster moupinensis AMX81602.1     8
 α-1,4-glucan-branching enzyme (GlgB)   Crassostrea angulata CCN27374.1     8
 ORF (fragment)   Crassostrea ariakensis AEF33381.1    
 α-amylase B (AmyB;Amy) 3.2.1.1 Crassostrea gigas AAL37207.1
ABB80387.1
ABB80388.1
ABR37235.1
ACC77978.1
ACC77979.1
ACC77980.1
CAD43101.1
CAD43102.1
CAD43103.1
CAD43104.1
Q8I7E4
Q8I7E5
Q8I7E6
Q8I7E7
Q8WSG9
  24
 α-amylase A (AmyA;Amy) 3.2.1.1 Crassostrea gigas AAL37183.1
ACB29736.1
ACC77975.1
ACC77976.1
ACC77977.1
CAA69658.1
CAD43095.1
CAD43096.1
CAD43097.1
CAD43098.1
CAD43099.1
CAD43100.1
O02622
Q8I080
Q8I0T4
Q8I7E8
Q8WSH2
  24
 Agl (fragment)   Crassostrea gigas CAD79439.1 Q86G99  
 AmY (fragment)   Crassostrea gigas AEA72216.1    
 starch branching enzyme I, partial (SbeI) (fragment)   Crataegus scabrifolia AMX81603.1     8
 CD98-related protein   Cricetulus griseus AAB97631.1 O55221   34
 CGB_A3550C   Cryptococcus gattii WM276 ADV19568.1     8
 CGB_F5660C   Cryptococcus gattii WM276 ADV23114.1     30
 CGB_B1340C   Cryptococcus gattii WM276 ADV20192.1     1
 CGB_E4540C   Cryptococcus gattii WM276 ADV22582.1     1
 CGB_J0390W   Cryptococcus gattii WM276 ADV24562.1     25
 CGB_G0540W   Cryptococcus gattii WM276 ADV23254.1     5
 CGB_G0300C   Cryptococcus gattii WM276 ADV23282.1     22
 CGB_J0550C   Cryptococcus gattii WM276 ADV24576.1     1
 CGB_E0010C (fragment)   Cryptococcus gattii WM276 ADV22324.1     40
 CGB_K1010W   Cryptococcus gattii WM276 ADV25090.1     1
 CNAG_05913   Cryptococcus neoformans var. grubii H99 AFR96233.1     30
 CNAG_00393   Cryptococcus neoformans var. grubii H99 AFR92526.1     8
 CNAG_00122   Cryptococcus neoformans var. grubii H99 AFR92258.1     1
 CNAG_02189   Cryptococcus neoformans var. grubii H99 AFR95631.1     1
 CNAG_03120   Cryptococcus neoformans var. grubii H99 AFR96345.1
AFR96345.2
AGV14519.1
    22
 CNAG_05264   Cryptococcus neoformans var. grubii H99 AFR94522.1
AGV14255.1
    1
 CNAG_03146   Cryptococcus neoformans var. grubii H99 AFR96372.1
AFR96372.2
    5
 CNAG_04879   Cryptococcus neoformans var. grubii H99 AFR97337.1
AFR97337.2
    25
 CNAG_06260   Cryptococcus neoformans var. grubii H99 AFR98494.1     40
 CNAG_01940   Cryptococcus neoformans var. grubii H99 AFR98135.1
AGV14739.1
    1
 CKF44_001733   Cryptococcus neoformans var. grubii KN99 AUB28238.1     1
 CKF44_001971   Cryptococcus neoformans var. grubii KN99 AUB25461.1     1
 CKF44_004716 (fragment)   Cryptococcus neoformans var. grubii KN99 AUB24185.1     1
 CKF44_004380   Cryptococcus neoformans var. grubii KN99 AUB27346.1     25
 CKF44_001733 (fragment)   Cryptococcus neoformans var. grubii KN99 AUB28239.1     1
 CKF44_005606   Cryptococcus neoformans var. grubii KN99 AUB28649.1     40
 CKF44_004716   Cryptococcus neoformans var. grubii KN99 AUB24184.1     1
 CKF44_002774   Cryptococcus neoformans var. grubii KN99 AUB26252.1     22
 CKF44_002799   Cryptococcus neoformans var. grubii KN99 AUB26281.1     5
 CKF44_005321   Cryptococcus neoformans var. grubii KN99 AUB26127.1     30
 CKF44_002774   Cryptococcus neoformans var. grubii KN99 AUB26251.1     22
 CKF44_000113   Cryptococcus neoformans var. grubii KN99 AUB21666.1     1
 CKF44_000329   Cryptococcus neoformans var. grubii KN99 AUB21968.1     8
 CNG04200   Cryptococcus neoformans var. neoformans JEC21 AAW44866.1
AAW44867.1
Q5KDF2   5
 CNN00140   Cryptococcus neoformans var. neoformans JEC21 AAW47005.1
AAW47005.2
Q5K7E4   40
 CNA03810   Cryptococcus neoformans var. neoformans JEC21 AAW40900.1 P0CN82   8
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