Glycoside Hydrolase Family 13

Activities in Familyα-amylase (EC 3.2.1.1); pullulanase (EC 3.2.1.41); cyclomaltodextrin glucanotransferase (EC 2.4.1.19); cyclomaltodextrinase (EC 3.2.1.54); trehalose-6-phosphate hydrolase (EC 3.2.1.93); oligo-α-glucosidase (EC 3.2.1.10); maltogenic amylase (EC 3.2.1.133); neopullulanase (EC 3.2.1.135); α-glucosidase (EC 3.2.1.20); maltotetraose-forming α-amylase (EC 3.2.1.60); isoamylase (EC 3.2.1.68); glucodextranase (EC 3.2.1.70); maltohexaose-forming α-amylase (EC 3.2.1.98); maltotriose-forming α-amylase (EC 3.2.1.116); branching enzyme (EC 2.4.1.18); trehalose synthase (EC 5.4.99.16); 4-α-glucanotransferase (EC 2.4.1.25); maltopentaose-forming α-amylase (EC 3.2.1.-) ; amylosucrase (EC 2.4.1.4) ; sucrose phosphorylase (EC 2.4.1.7); malto-oligosyltrehalose trehalohydrolase (EC 3.2.1.141); isomaltulose synthase (EC 5.4.99.11); malto-oligosyltrehalose synthase (EC 5.4.99.15); amylo-α-1,6-glucosidase (EC 3.2.1.33); α-1,4-glucan: phosphate α-maltosyltransferase (EC 2.4.99.16); 6'-P-sucrose phosphorylase (EC 2.4.1.-); amino acid transporter
Mechanism Retaining
ClanGH-H
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseAsp (experimental)
Catalytic Proton DonorGlu (experimental)
NoteNew: many members have been assigned to subfamilies as described by Stam et al. (2006) Protein Eng Des Sel. 19, 555-562 (PMID: 17085431)
External resourcesCAZypedia; EBI Protein of the Month; HOMSTRAD; PDB Molecule of the Month; PRINTS;
Commercial Enzyme Provider(s)MEGAZYME; PROZOMIX;
Statistics GenBank accession (66285); Uniprot accession (7872); PDB accession (486); 3D entries (114); cryst (2)
All (61404) Archaea (391) Bacteria (57550) Eukaryota (3337) unclassified (126) Structure (114 - 2 cryst) Characterized (815)
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | ... | 34 |
Eukaryota
Protein Name EC#OrganismGenBank UniprotPDB/3D Subf
 AmY   Colobus angolensis ABW02886.1 A8HDI0   24
 starch branching enzyme A (SbeA)   Colocasia esculenta ABP96984.1
ANC33494.1
A5HSI0   8
 ORF (fragment)   Coptotermes formosanus AGM32281.1     17
 ORF (fragment)   Coptotermes formosanus AGM32321.1     17
 ORF (fragment)   Coptotermes formosanus AGM32822.1     17
 ORF (fragment)   Coptotermes formosanus AGM32823.1     17
 α-amylase (Amy)   Corbicula fluminea AAO17927.2 Q8I9P8  
 A9K55_000120   Cordyceps militaris ATCC 34164 ATY67289.1     8
 A9K55_005467   Cordyceps militaris ATCC 34164 ATY61276.1     25
 A9K55_008949   Cordyceps militaris ATCC 34164 ATY62175.1     40
 A9K55_007977   Cordyceps militaris ATCC 34164 ATY61965.1     40
 A9K55_002235   Cordyceps militaris ATCC 34164 ATY59031.1     5
 glycogen debranching enzyme/amylo-α-1,6-glucosidase, partial (AgL)   Coremiostelium polycephalum MY1-1 AOE43286.1     25
 alpha amylase   Cosmopolites sordidus AKN63428.1     15
 ORF   Cotesia congregata CAR82255.1 B9W4L8   15
 starch branching enzyme I, partial (SbeI) (fragment)   Cotoneaster franchetii AMX81600.1     8
 starch branching enzyme I, partial (SbeI) (fragment)   Cotoneaster hebephyllus AMX81601.1     8
 starch branching enzyme I, partial (SbeI) (fragment)   Cotoneaster moupinensis AMX81602.1     8
 ORF (fragment)   Crangon crangon AWU67108.1     24
 ORF   Crangon crangon AWU67099.1     24
 ORF (fragment)   Crangon crangon AWU67109.1     24
 ORF (fragment)   Crangon crangon AWU67105.1    
 ORF (fragment)   Crangon crangon AWU67102.1    
 ORF (fragment)   Crangon crangon AWU67103.1    
 ORF   Crangon crangon AWU67110.1    
 ORF (fragment)   Crangon crangon AWU67106.1     24
 ORF (fragment)   Crangon crangon AWU67101.1    
 ORF   Crangon crangon AWU67104.1    
 ORF (fragment)   Crangon crangon AWU67100.1    
 ORF   Crangon crangon AWU67107.1     24
 α-1,4-glucan-branching enzyme (GlgB)   Crassostrea angulata CCN27374.1     8
 ORF (fragment)   Crassostrea ariakensis AEF33381.1    
 α-amylase B (AmyB;Amy) 3.2.1.1 Crassostrea gigas AAL37207.1
ABB80387.1
ABB80388.1
ABR37235.1
ACC77978.1
ACC77979.1
ACC77980.1
CAD43101.1
CAD43102.1
CAD43103.1
CAD43104.1
Q8I7E4
Q8I7E5
Q8I7E6
Q8I7E7
Q8WSG9
  24
 α-amylase A (AmyA;Amy) 3.2.1.1 Crassostrea gigas AAL37183.1
ACB29736.1
ACC77975.1
ACC77976.1
ACC77977.1
CAA69658.1
CAD43095.1
CAD43096.1
CAD43097.1
CAD43098.1
CAD43099.1
CAD43100.1
O02622
Q8I080
Q8I0T4
Q8I7E8
Q8WSH2
  24
 Agl (fragment)   Crassostrea gigas CAD79439.1 Q86G99  
 AmY (fragment)   Crassostrea gigas AEA72216.1    
 starch branching enzyme I, partial (SbeI) (fragment)   Crataegus scabrifolia AMX81603.1     8
 CD98-related protein   Cricetulus griseus AAB97631.1 O55221   34
 CGB_A3550C   Cryptococcus gattii WM276 ADV19568.1     8
 CGB_F5660C   Cryptococcus gattii WM276 ADV23114.1     30
 CGB_B1340C   Cryptococcus gattii WM276 ADV20192.1     1
 CGB_E4540C   Cryptococcus gattii WM276 ADV22582.1     1
 CGB_J0390W   Cryptococcus gattii WM276 ADV24562.1     25
 CGB_G0540W   Cryptococcus gattii WM276 ADV23254.1     5
 CGB_G0300C   Cryptococcus gattii WM276 ADV23282.1     22
 CGB_J0550C   Cryptococcus gattii WM276 ADV24576.1     1
 CGB_E0010C (fragment)   Cryptococcus gattii WM276 ADV22324.1     40
 CGB_K1010W   Cryptococcus gattii WM276 ADV25090.1     1
 CNAG_05913   Cryptococcus neoformans var. grubii H99 AFR96233.1     30
 CNAG_00393   Cryptococcus neoformans var. grubii H99 AFR92526.1     8
 CNAG_00122   Cryptococcus neoformans var. grubii H99 AFR92258.1     1
 CNAG_02189   Cryptococcus neoformans var. grubii H99 AFR95631.1     1
 CNAG_03120   Cryptococcus neoformans var. grubii H99 AFR96345.1
AFR96345.2
AGV14519.1
    22
 CNAG_05264   Cryptococcus neoformans var. grubii H99 AFR94522.1
AGV14255.1
    1
 CNAG_03146   Cryptococcus neoformans var. grubii H99 AFR96372.1
AFR96372.2
    5
 CNAG_04879   Cryptococcus neoformans var. grubii H99 AFR97337.1
AFR97337.2
    25
 CNAG_06260   Cryptococcus neoformans var. grubii H99 AFR98494.1     40
 CNAG_01940   Cryptococcus neoformans var. grubii H99 AFR98135.1
AGV14739.1
    1
 CKF44_001733   Cryptococcus neoformans var. grubii KN99 AUB28238.1     1
 CKF44_001971   Cryptococcus neoformans var. grubii KN99 AUB25461.1     1
 CKF44_004716 (fragment)   Cryptococcus neoformans var. grubii KN99 AUB24185.1     1
 CKF44_004380   Cryptococcus neoformans var. grubii KN99 AUB27346.1     25
 CKF44_001733 (fragment)   Cryptococcus neoformans var. grubii KN99 AUB28239.1     1
 CKF44_005606   Cryptococcus neoformans var. grubii KN99 AUB28649.1     40
 CKF44_004716   Cryptococcus neoformans var. grubii KN99 AUB24184.1     1
 CKF44_002774   Cryptococcus neoformans var. grubii KN99 AUB26252.1     22
 CKF44_002799   Cryptococcus neoformans var. grubii KN99 AUB26281.1     5
 CKF44_005321   Cryptococcus neoformans var. grubii KN99 AUB26127.1     30
 CKF44_002774   Cryptococcus neoformans var. grubii KN99 AUB26251.1     22
 CKF44_000113   Cryptococcus neoformans var. grubii KN99 AUB21666.1     1
 CKF44_000329   Cryptococcus neoformans var. grubii KN99 AUB21968.1     8
 CNG04200   Cryptococcus neoformans var. neoformans JEC21 AAW44866.1
AAW44867.1
Q5KDF2   5
 CNN00140   Cryptococcus neoformans var. neoformans JEC21 AAW47005.1
AAW47005.2
Q5K7E4   40
 CNA03810   Cryptococcus neoformans var. neoformans JEC21 AAW40900.1 P0CN82   8
 CNL03660   Cryptococcus neoformans var. neoformans JEC21 AAW46412.1 Q5K924   1
 CNK02760   Cryptococcus neoformans var. neoformans JEC21 AAW46356.1 Q5K993   1
 CNF00610   Cryptococcus neoformans var. neoformans JEC21 AAW43932.1 Q5KFT6   30
 CNJ03090   Cryptococcus neoformans var. neoformans JEC21 AAW45872.1 Q5KA48   25
 α-1,3-glucan synthase (Ags1;CNG04420) 2.4.1.183 Cryptococcus neoformans var. neoformans JEC21 AAW44814.1
AAR97368.1
Q5KDD1   22
 CNH03660   Cryptococcus neoformans var. neoformans JEC21 AAW45221.1 Q5K924   1
 CNA01120   Cryptococcus neoformans var. neoformans JEC21 AAW41268.1 Q5KPY6   1
 CNE03480   Cryptococcus neoformans var. neoformans JEC21 AAW43607.1 Q5KGI6   1
 α-amylase (Amy-CS2) 3.2.1.1 Cryptococcus sp. S-2 BAA12010.1
BAA12011.1
Q92394   1
 1MB.26   Cryptosporidium parvum CAD98636.1 Q7YY51   25
 cgd6_3280 (1MB.422)   Cryptosporidium parvum CAD98370.1
EAK89954.1
Q7YYW0   9
 1MB.513   Cryptosporidium parvum CAD98416.1 Q7YYR4  
 α-amylase (Amy2A)   Ctenopharyngodon idella ACX35465.1 D0EM61   24
 pancreatic amylase (AmY) (fragment)   Ctenopharyngodon idella ACV04936.1 D4HNE8   24
 α-amylase (fragment)   Ctenopharyngodon idella ADY39424.1     24
 starch branching enzyme   Cucumis melo subsp. melo ADN33992.1 E5GBZ3   8
 cytosolic α-amylase   Cucumis melo subsp. melo ADN34132.1 E5GCD3   6
 starch branching enzyme I (CS_SBa_056C11) (fragment)   Cucumis sativus ACA35282.1 B3U2B7   8
 starch branching enzyme I (CS_SBa_075L23)   Cucumis sativus ACA35286.1 B3U2C1   8
 SbeII (fragment)   Cucurbita moschata AEV91543.1     8
 starch debranching enzyme, partial (IsaI) (fragment)   Cucurbita moschata AEV91544.1     11
 α-glucosidase / maltase 1 (Cpm1) (binary toxin-binding) 3.2.1.20 Culex pipiens AAL05443.1 Q95WY5   17
 maltase 1 (Cpm1) (fragment)   Culex pipiens BP ABN64095.1 A4KVA0   17
 maltase 1 (Cpm1) (possible frameshift)   Culex pipiens BP ABN64096.1 A4KVA1   17
 ORF   Culex pipiens pallens AAZ15878.1 Q4F8A2   8
 maltase 1 (Cpm1)   Culex pipiens S-LAB ABN64094.1 A4KV99   17
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