Glycoside Hydrolase Family 13

Activities in Familyα-amylase (EC 3.2.1.1); pullulanase (EC 3.2.1.41); cyclomaltodextrin glucanotransferase (EC 2.4.1.19); cyclomaltodextrinase (EC 3.2.1.54); trehalose-6-phosphate hydrolase (EC 3.2.1.93); oligo-α-glucosidase (EC 3.2.1.10); maltogenic amylase (EC 3.2.1.133); neopullulanase (EC 3.2.1.135); α-glucosidase (EC 3.2.1.20); maltotetraose-forming α-amylase (EC 3.2.1.60); isoamylase (EC 3.2.1.68); glucodextranase (EC 3.2.1.70); maltohexaose-forming α-amylase (EC 3.2.1.98); maltotriose-forming α-amylase (EC 3.2.1.116); branching enzyme (EC 2.4.1.18); trehalose synthase (EC 5.4.99.16); 4-α-glucanotransferase (EC 2.4.1.25); maltopentaose-forming α-amylase (EC 3.2.1.-) ; amylosucrase (EC 2.4.1.4) ; sucrose phosphorylase (EC 2.4.1.7); malto-oligosyltrehalose trehalohydrolase (EC 3.2.1.141); isomaltulose synthase (EC 5.4.99.11); malto-oligosyltrehalose synthase (EC 5.4.99.15); amylo-α-1,6-glucosidase (EC 3.2.1.33); α-1,4-glucan: phosphate α-maltosyltransferase (EC 2.4.99.16); 6'-P-sucrose phosphorylase (EC 2.4.1.-); amino acid transporter
Mechanism Retaining
ClanGH-H
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseAsp (experimental)
Catalytic Proton DonorGlu (experimental)
NoteNew: many members have been assigned to subfamilies as described by Stam et al. (2006) Protein Eng Des Sel. 19, 555-562 (PMID: 17085431)
External resourcesCAZypedia; EBI Protein of the Month; HOMSTRAD; PDB Molecule of the Month; PRINTS;
Commercial Enzyme Provider(s)MEGAZYME; PROZOMIX;
Statistics GenBank accession (54252); Uniprot accession (7858); PDB accession (465); 3D entries (110); cryst (2)
All (49476) Archaea (367) Bacteria (45982) Eukaryota (2997) unclassified (130) Structure (110 - 2 cryst) Characterized (812)
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | ... | 30 |
Eukaryota
Protein Name EC#OrganismGenBank UniprotPDB/3D Subf
 starch branching enzyme (fragment)   Culex tarsalis ACJ64305.1 B8RJ07   8
 α-glucosidase (fragment)   Culex tarsalis ACJ64310.1 C4N154   17
 α-amylase (fragment)   Culex tarsalis ACJ64321.1 B8RJ22  
 α-amylase (fragment)   Culex tarsalis ACJ64402.1 B8RJA3   15
 α-amylase (fragment)   Culex tarsalis ACJ64479.1 B8RJI0  
 α-amylase 3.2.1.1 Culex tarsalis AAA03350.1 Q23767   15
 maltase   Culicoides nubeculosus ACM40914.1 B9URL7   17
 maltase / allergen (Cul n 8)   Culicoides nubeculosus ADJ67272.1 D9IL18   17
 maltase / allergen (Cul o 1)   Culicoides obsoletus AGI16774.1     17
 α-amylase (Amy1;CsAMY1) (fragment)   Culicoides sonorensis AAU06472.1 Q66UE3  
 maltase / allergen (Mal1;CsMAL1;Cul s 1)   Culicoides sonorensis AAU06480.1 Q66UC5   17
 ORF (fragment)   Culicoides sonorensis AAV84200.1 Q5QBM4   17
 α-amylase (fragment)   Culter alburnus ADY39430.1     24
 α-amylase (Amy) (fragment)   Curtonotidae sp. FM-2005a AAY88835.1 Q3SCB3   15
 α-amylase (Amy) (fragment)   Curtonotidae sp. FM-2005b AAY88836.1 Q3SCB2   15
 α-amylase 3.2.1.1 Cuscuta reflexa AAA16513.1 Q42678   6
 CYME_CMB158C   Cyanidioschyzon merolae strain 10D BAM78952.1    
 CYME_CMD033C   Cyanidioschyzon merolae strain 10D BAM79124.1    
 CYME_CMH144C   Cyanidioschyzon merolae strain 10D BAM79815.1     8
 CYME_CMI294C   Cyanidioschyzon merolae strain 10D BAM80148.1     11
 CYME_CMP300C   Cyanidioschyzon merolae strain 10D BAM81898.1     14
 CYME_CMS197C   Cyanidioschyzon merolae strain 10D BAM82814.1     11
 CYFA0S_03e04170g   Cyberlindnera fabianii YJS4271 CDR39508.1     40
 CYFA0S_03e05952g   Cyberlindnera fabianii YJS4271 CDR39670.1     40
 CYFA0S_03e05974g   Cyberlindnera fabianii YJS4271 CDR39674.1     40
 CYFA0S_03e06634g   Cyberlindnera fabianii YJS4271 CDR39735.1     25
 CYFA0S_07e01398g   Cyberlindnera fabianii YJS4271 CDR41381.1     8
 starch branching enzyme I, partial (SbeI) (fragment)   Cydonia oblonga AMX81604.1     8
 α-amylase   Cynoglossus semilaevis AGT37610.1     24
 rBAT protein (RbaT)   Cyprinus carpio AEX13745.1     17
 RbaT (fragment)   Cyprinus carpio ABY57295.1 B0FGW1   35
 α-amylase (fragment)   Cyprinus carpio jian AFB76589.1     24
 α-amylase (Amy) (fragment)   Cypselidae sp. FM-2005 AAY88837.1 Q3SCB1   15
 α-amylase   Dactylis glomerata ACY38052.1 D0VEB9   6
 α-amylase   Dactylis glomerata ACZ72923.1 D2K7Z9   6
 DKEY-202M23.2-001 (partial)   Danio rerio CAX14245.1 B8JJX3   17
 ORF   Danio rerio AAH44497.1
AAH63982.1
Q803G1   34
 Unknown (protein for MGC:66313)   Danio rerio AAH54681.1
AAI65756.1
NP_956722.1
Q7SYK9   24
 α-amylase 3 (Amy2A) (pancreatic)   Danio rerio AAH54669.1
AAH62867.1
CAQ15469.1
Q7SYL6   24
 Unknown (protein for MGC:92137)   Danio rerio AAH75900.1 Q6DHR7   24
 Unknown (protein for MGC:158423)   Danio rerio AAI28866.1 A1A5Y9   34
 solute carrier (Slc3a2)   Danio rerio AAH53236.1
AAG37838.1
AAI59203.1
NP_571676.1
Q7T2P3
Q9DDS9
  34
 DEHA0A14300g   Debaryomyces hansenii CBS767 CAG84911.1 Q6BXY6   40
 DEHA0B01650g   Debaryomyces hansenii CBS767 CAG85024.1 Q6BXN1   8
 DEHA0E00627g   Debaryomyces hansenii CBS767 CAG87533.1 Q6BR20   40
 DEHA2C06864g   Debaryomyces hansenii CBS767 CAG86039.2     25
 α-amylase (Amy) (fragment)   Delia radicum AAY88825.1 Q3SCC3   15
 α-amylase (Amy) (fragment)   Delia radicum AAY88826.1 Q3SCC2   15
 α-amylase (Amy) (fragment)   Delia radicum AAY88827.1 Q3SCC1   15
 unknown   Dendroctonus ponderosae AEE61654.1     15
 unknown   Dendroctonus ponderosae AEE62033.1     8
 unknown (fragment)   Dendroctonus ponderosae AEE61835.1     17
 allergen (Der f 4)   Dermatophagoides farinae AHX03180.1     24
 Der f 4 allergen (Der_f_4.0107)   Dermatophagoides farinae AIP86945.1     24
 Der f 4 allergen (Der_f_4.0101)   Dermatophagoides farinae AIP86939.1     24
 Der f 4 allergen (Der_f_4.0104)   Dermatophagoides farinae AIP86942.1     24
 Der f 4 allergen (Der_f_4.0106)   Dermatophagoides farinae AIP86944.1     24
 Der f 4 allergen (Der_f_4.0105)   Dermatophagoides farinae AIP86943.1     24
 Der f 4 allergen (Der_f_4.0103)   Dermatophagoides farinae AIP86941.1     24
 Der f 4 allergen (Der_f_4.0108)   Dermatophagoides farinae AIP86946.1     24
 Der f 4 allergen (Der_f_4.0102)   Dermatophagoides farinae AIP86940.1     24
 Der f 4 allergen   Dermatophagoides farinae AJF93907.1     24
 α-amylase (Der p 4;Derp4) (allergen) 3.2.1.1 Dermatophagoides pteronyssinus AAD38942.1 P49274
Q9Y197
  24
 α-amylase 3.2.1.1 Diabrotica virgifera virgifera AAF20998.1 Q9U406   15
 Amy1   Diatraea saccharalis AAP92665.1 Q7YXU5   15
 Amy3   Diatraea saccharalis AAP97394.1 Q7YXJ3   15
 Amy2   Diatraea saccharalis AAP97393.1 Q7YXJ4   15
 α-amylase (Amy2) (fragment)   Dicentrarchus labrax CAC33515.1 Q98TR6  
 starch branching enzyme I, partial (SbeI) (fragment)   Dichotomanthes tristaniicarpa AMX81605.1     8
 alpha amylase 2 (Amy2)   Dictyosoma burgeri AMQ67310.1     24
 glycogen debranching enzyme/amylo-α-1,6-glucosidase (AgL)   Dictyostelium deminutivum MexM19A AOE43284.1     25
 branching enzyme (GlgB) (fragment)   Dictyostelium discoideum AAC31541.1 O76547  
 AmyA (fragment)   Dictyostelium discoideum AAB70852.1 O15751  
 dd_01601g34   Dictyostelium discoideum AX4 AAL99321.1
AAM08768.2
Q8T189   8
 DDB_0214924 (AmyA)   Dictyostelium discoideum AX4 XP_640516.1     1
 glycogen debranching enzyme/amylo-α-1,6-glucosidase (AgL)   Dictyostelium polycarpum OhioWILDS AOE43285.1     25
 glycogen debranching enzyme/amylo-α-1,6-glucosidase, partial (AgL)   Dictyostelium polycephalum MY1-1 AOE43286.1     25
 ORF (fragment)   Didymium dachnayum ABD72546.1 Q207W9  
 α-amylase (Amy) (fragment)   Diopsidae sp. FM-2005 AAY88839.1 Q3SCA9   15
 α-amylase 1   Diplodus sargus ABX89620.1 B6CGL7   24
 sucrase (fragment)   Diuraphis noxia AEP03183.1
AFK66761.1
    17
 ORF (fragment)   Dreissena polymorpha AEF56576.1     24
 amylase, partial (fragment)   Dreissena rostriformis bugensis CTQ87316.1     24
 alpha amylase-related-protein, partial (AmyreL) (fragment)   Drosophila acanthoptera 15090-1693.00 AHL43631.1     15
 alpha amylase, partial (fragment)   Drosophila acanthoptera 15090-1693.00 AHL43643.1     15
 Amyrel (fragment)   Drosophila adamsi AAW66433.1     15
 α-amylase (Amy) (fragment)   Drosophila affinis ATLANTA AAN16147.1     15
 amylase related protein (Amyrel)   Drosophila affinis ATLANTA AAN16153.1     15
 Amyrel   Drosophila albirostris AAW64450.1     15
 Amyrel   Drosophila albomicans AAO14605.1 Q8I9R4   15
 CG33138 protein, partial (fragment)   Drosophila albomicans CM137 BAR88891.1     8
 amyrel protein, partial (fragment)   Drosophila albomicans CM137 BAR88651.1
BAR88652.1
BAR88653.1
BAR88654.1
BAR88655.1
BAR88656.1
BAR88657.1
BAR88658.1
BAR88659.1
BAR88660.1
BAR88661.1
BAR88662.1
BAR88663.1
BAR88664.1
BAR88665.1
BAR88666.1
BAR88667.1
BAR88668.1
BAR88669.1
BAR88670.1
BAR88671.1
BAR88672.1
BAR88673.1
BAR88674.1
BAR88675.1
BAR88676.1
BAR88677.1
BAR88678.1
BAR88679.1
BAR88680.1
BAR88681.1
BAR88682.1
    15
 CG33138 protein, partial (fragment)   Drosophila albomicans GZL3 BAR88892.1     8
 CG33138 protein, partial (fragment)   Drosophila albomicans HNZ12 BAR88877.1     8
 CG33138 protein, partial (fragment)   Drosophila albomicans ISG243 BAR88878.1     8
 CG33138 protein, partial (fragment)   Drosophila albomicans K39 BAR88879.1     8
 CG33138 protein, partial (fragment)   Drosophila albomicans KKU204 BAR88880.1     8
 CG33138 protein, partial (fragment)   Drosophila albomicans KM7 BAR88890.1     8
 CG33138 protein, partial (fragment)   Drosophila albomicans KM7 BAR88906.1     8
 CG33138 protein, partial (fragment)   Drosophila albomicans KMT408 BAR88881.1     8
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