Glycoside Hydrolase Family 13

Activities in Familyα-amylase (EC 3.2.1.1); pullulanase (EC 3.2.1.41); cyclomaltodextrin glucanotransferase (EC 2.4.1.19); cyclomaltodextrinase (EC 3.2.1.54); trehalose-6-phosphate hydrolase (EC 3.2.1.93); oligo-α-glucosidase (EC 3.2.1.10); maltogenic amylase (EC 3.2.1.133); neopullulanase (EC 3.2.1.135); α-glucosidase (EC 3.2.1.20); maltotetraose-forming α-amylase (EC 3.2.1.60); isoamylase (EC 3.2.1.68); glucodextranase (EC 3.2.1.70); maltohexaose-forming α-amylase (EC 3.2.1.98); maltotriose-forming α-amylase (EC 3.2.1.116); branching enzyme (EC 2.4.1.18); trehalose synthase (EC 5.4.99.16); 4-α-glucanotransferase (EC 2.4.1.25); maltopentaose-forming α-amylase (EC 3.2.1.-) ; amylosucrase (EC 2.4.1.4) ; sucrose phosphorylase (EC 2.4.1.7); malto-oligosyltrehalose trehalohydrolase (EC 3.2.1.141); isomaltulose synthase (EC 5.4.99.11); malto-oligosyltrehalose synthase (EC 5.4.99.15); amylo-α-1,6-glucosidase (EC 3.2.1.33); α-1,4-glucan: phosphate α-maltosyltransferase (EC 2.4.99.16); 6'-P-sucrose phosphorylase (EC 2.4.1.-); amino acid transporter
Mechanism Retaining
ClanGH-H
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseAsp (experimental)
Catalytic Proton DonorGlu (experimental)
NoteNew: many members have been assigned to subfamilies as described by Stam et al. (2006) Protein Eng Des Sel. 19, 555-562 (PMID: 17085431)
External resourcesCAZypedia; EBI Protein of the Month; HOMSTRAD; PDB Molecule of the Month; PRINTS;
Commercial Enzyme Provider(s)MEGAZYME; PROZOMIX;
Statistics GenBank accession (54252); Uniprot accession (7858); PDB accession (465); 3D entries (110); cryst (2)
All (49476) Archaea (367) Bacteria (45982) Eukaryota (2997) unclassified (130) Structure (110 - 2 cryst) Characterized (812)
| 1 | ... | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | ... | 30 |
Eukaryota
Protein Name EC#OrganismGenBank UniprotPDB/3D Subf
 CG33138 protein, partial (fragment)   Drosophila albomicans KT48 BAR88882.1     8
 CG33138 protein, partial (fragment)   Drosophila albomicans KT48 BAR88898.1     8
 CG33138 protein, partial (fragment)   Drosophila albomicans MMY1 BAR88883.1     8
 CG33138 protein, partial (fragment)   Drosophila albomicans MMY1 BAR88899.1     8
 CG33138 protein, partial (fragment)   Drosophila albomicans NG3 BAR88884.1     8
 CG33138 protein, partial (fragment)   Drosophila albomicans TAK2 BAR88885.1     8
 CG33138 protein, partial (fragment)   Drosophila albomicans TOK5 BAR88886.1     8
 CG33138 protein, partial (fragment)   Drosophila albomicans TSN7 BAR88903.1     8
 CG33138 protein, partial (fragment)   Drosophila albomicans TSN7 BAR88887.1     8
 CG33138 protein, partial (fragment)   Drosophila albomicans WL1 BAR88904.1     8
 CG33138 protein, partial (fragment)   Drosophila albomicans WL1 BAR88888.1     8
 CG33138 protein, partial (fragment)   Drosophila albomicans X108 BAR88889.1     8
 CG33138 protein, partial (fragment)   Drosophila albomicans X108 BAR88905.1     8
 amylase-related protein (Amyrel) (fragment)   Drosophila ambigua AAN16193.1     15
 α-amylase (Amy) (fragment)   Drosophila ambigua ECOSSE AAN16140.1     15
 Amyrel (fragment)   Drosophila americana AAW66434.1     15
 maltase 1 (Mav1) (fragment)   Drosophila americana 15010-0951.0 AAP12720.1 Q86FU8  
 Amyrel (fragment)   Drosophila americana texana AAW66445.1     15
 α-amylase 38/58 (Amy;Amy35;Amy58;AmyTBU118)   Drosophila ananassae AAC79123.1
AAC47353.1
AAC79122.1
BAA22481.1
O15947
O18345
Q23835
  15
 α-amylase 4N (Amy4N)   Drosophila ananassae AAC48343.1
AAC47352.1
Q23834   15
 α-amylase C1 3.2.1.1 Drosophila ananassae AAC35243.1 O77407   15
 amylase C1 (fragment)   Drosophila ananassae AAC47354.1 Q23836  
 Amy C6 (Amyrel)   Drosophila ananassae AAC39090.3 O18344   15
 Amyrel (fragment)   Drosophila angularis AAW66435.1     15
 putative amylase (fragment)   Drosophila aracataca AAC47372.1 Q23837  
 Amyrel   Drosophila aracataca AAW64455.1     15
 alpha amylase-related-protein, partial (AmyreL) (fragment)   Drosophila aracataca 15040-1171.00 AHL43632.1     15
 alpha amylase, partial (fragment)   Drosophila aracataca 15040-1171.00 AHL43644.1     15
 Amyrel (fragment)   Drosophila aracea AAW66436.1     15
 Amyrel   Drosophila ararama AAW64451.1     15
 Amyrel   Drosophila arawakana AAO84660.1 Q86N69   15
 Amy (fragment)   Drosophila arawakana AAQ13446.1 Q5NKY1   15
 amylase-related protein, partial (AmyreL) (fragment)   Drosophila arizonae AJP07832.1     15
 Amyrel   Drosophila asahinai AAL99575.1 Q8T7Y0   15
 α-amylase (Amy) (fragment)   Drosophila athabasca AAN16149.1     15
 α-amylase (Amy) (fragment)   Drosophila athabasca AAN16150.1 Q71V28   15
 amylase-related protein (Amyrel) (fragment)   Drosophila athabasca AAN16196.1     15
 Amyrel   Drosophila atripex AAC39104.3 O77011   15
 putative amylase   Drosophila auraria AAC39113.2 O77020   15
 Amy / Amy3 (fragment)   Drosophila auraria BAA22482.1 O15948   15
 Amy / Amy6 (fragment)   Drosophila auraria BAA22483.1 O15949   15
 α-amylase (fragment)   Drosophila auraria 14028-0471.0 (BOWLING GREEN STOCK CENTER) AAG42549.1     15
 amylase (fragment)   Drosophila auraria SHANGHAI-1 BAC53957.1 Q8IAI3   15
 α-amylase (fragment)   Drosophila azteca AAN16158.1     15
 amylase-related protein (Amyrel) (fragment)   Drosophila azteca 14012-0171-4 AAN16170.1     15
 AmyreL (fragment)   Drosophila baimaii AEM77111.1     15
 amylase (fragment)   Drosophila baimaii 14028.0481.0 BAC53965.1 Q8IAF2   15
 putative amylase   Drosophila bakoue AAC39112.2 O77019   15
 Amyrel   Drosophila barbarae AAL99577.1 Q8T7X8   15
 amylase (fragment)   Drosophila barbarae BAC53966.1 Q8IAF1   15
 amylase (fragment)   Drosophila barbarae BAC53967.1 Q8IAF0   15
 Amyrel   Drosophila biarmipes AAO14606.1 Q8I9R3   15
 amylase   Drosophila biarmipes IND_DBR_U4 ANZ79221.1     15
 α-amylase (fragment)   Drosophila biauraria AAM69518.1 Q8MX70   15
 Amyrel   Drosophila biauraria AAF25714.2 Q86S14   15
 Amy2 (fragment)   Drosophila biauraria 14028-0501.0 (BOWLING GREEN STOCK CENTER) AAG42550.1     15
 Amyrel   Drosophila bicornuta AAF25715.1 Q86S13   15
 Amy2 (fragment)   Drosophila bicornuta 14028-0511.1 (BOWLING GREEN STOCK CENTER) AAG42559.1     15
 Amy1 (fragment)   Drosophila bicornuta 14028-0511.1 (BOWLING GREEN STOCK CENTER) AAG42558.1     15
 Amyrel   Drosophila bifasciata AAL99395.1
AAN16155.1
Q8T7W5   15
 α-amylase (Amy) (fragment)   Drosophila bifasciata AAN16152.1     15
 putative amylase (fragment)   Drosophila bifasciata BAA22484.1 O15950   15
 Amy (fragment)   Drosophila bifurca AAQ13450.1 Q5NKX7   15
 Amy (fragment)   Drosophila bipectinata BAA22485.1 O15951
O18665
  15
 Amy / Amy4 (fragment)   Drosophila bipectinata BAA22486.1 O15952   15
 putative amylase (fragment)   Drosophila bipectinata AAC47373.1 Q23842  
 putative amylase (fragment)   Drosophila bipectinata AAC47374.1 Q23843  
 Amyrel   Drosophila bipectinata AAF25718.1 Q9NJN8   15
 amylase   Drosophila bipectinata IND_DBP_U14 ANZ79222.1     15
 AmyreL (fragment)   Drosophila birchii AEM77112.1     15
 amylase (fragment)   Drosophila birchii 14028.0521.0 BAC53968.1
BAC53969.1
Q8I057   15
 amylase distal, partial (Amy-D) (fragment)   Drosophila biseriata AFM76789.1     15
 AmyreL (fragment)   Drosophila bocki AEM77113.1     15
 α-amylase (Amy4) 3.2.1.1 Drosophila bocki A65 BAA95436.1 Q9NKZ0   15
 α-amylase (Amy3) 3.2.1.1 Drosophila bocki A65 BAA95435.1 Q9NKZ1   15
 α-amylase (Amy2) 3.2.1.1 Drosophila bocki A65 BAA95434.1 Q9NKZ2   15
 α-amylase (Amy1) 3.2.1.1 Drosophila bocki A65 BAA95433.1 Q9NKZ3   15
 α-amylase (Amy1) 3.2.1.1 Drosophila bocki A94 BAB91544.1 Q9NKZ2   15
 α-amylase (Amy2) 3.2.1.1 Drosophila bocki A94 BAB91547.1 Q8N0P7   15
 α-amylase (Amy1) 3.2.1.1 Drosophila bocki AO-1 BAB91546.1 Q8N0P8   15
 α-amylase (Amy2) 3.2.1.1 Drosophila bocki AO-1 BAB91549.1 Q8N0P5   15
 α-amylase (Amy1) 3.2.1.1 Drosophila bocki IRO2-37 BAB91545.1 Q8N0P9   15
 α-amylase (Amy2) 3.2.1.1 Drosophila bocki IRO2-37 BAB91548.1 Q8N0P6   15
 putative amylase   Drosophila bocqueti AAC39100.2 O76284   15
 amylase (fragment)   Drosophila bocqueti L139 BAC53970.1 Q8IAE9   15
 amylase (fragment)   Drosophila bocqueti L139 BAC53971.1 Q8IAE8   15
 Amyrel   Drosophila bromeliae AAW64452.1     15
 alpha amylase, partial (fragment)   Drosophila bromeliae 15085-1682.00 AHL43645.1     15
 Amyrel   Drosophila burlai AAL99583.1 Q8T7X3   15
 amylase (fragment)   Drosophila burlai L111 BAC53972.1 Q8IAE7   15
 amylase (fragment)   Drosophila burlai L111 BAC53973.1 Q8IAE6   15
 Dbus_chr2Rg503   Drosophila busckii ALC40924.1     17
 Dbus_chr2Lg1433 (fragment)   Drosophila busckii ALC39348.1     17
 Dbus_chr2Rg506   Drosophila busckii ALC40927.1     17
 Dbus_chr2Rg511   Drosophila busckii ALC40932.1     17
 Dbus_chr2Rg507   Drosophila busckii ALC40928.1     17
 Dbus_chr2Rg505 (fragment)   Drosophila busckii ALC40926.1     17
 Dbus_chr2Rg1249   Drosophila busckii ALC41670.1     25
 Dbus_chr2Rg510   Drosophila busckii ALC40931.1     17
 Dbus_chr2Rg461   Drosophila busckii ALC40882.1     8
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