Carbohydrate-Binding Module Family 13

Activities in FamilyModules of approx. 150 residues which always appear as a threefold internal repeat. The only apparent exception to this, xylanase II of Actinomadura sp. FC7 (GenBank U08894), is in fact not completely sequenced. These modules were first identified in several plant lectins such as ricin or agglutinin of Ricinus communis which bind galactose residues. The three-dimensional structure of a plant lectin has been determined and displays a pseudo-threefold symmetry in accord with the observed sequence threefold repeat. These modules have since been found in a number of other proteins of various functions including glycoside hydrolases and glycosyltransferases. While in the plant lectins this module binds mannose, binding to xylan has been demonstrated in the Streptomyces lividans xylanase A and arabinofuranosidase B. Binding to GalNAc has been shown for the corresponding module of GalNAc transferase 4. For the other proteins, the binding specificity of these modules has not been established. The pseudo three-fold symmetry of the CBM13 module has now been confirmed in the 3-D structure of the intact, two-domain, xylanase of Streptomyces olivaceoviridis.
3D Structure Statusβ-trefoil
NotePreviously known as cellulose-binding domain family XIII (CBD XIII).
External resourcesHOMSTRAD;
Statistics GenBank accession (5439); Uniprot accession (902); PDB accession (142); 3D entries (56); cryst (1)
All (5178) Archaea (18) Bacteria (4566) Eukaryota (557) Viruses (26) unclassified (11) Structure (56 - 1 cryst) Characterized (99)
| 1 | ... | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | ... | 46 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 BM43_3411   Burkholderia gladioli ATCC 10248 AJW98162.1    
 CO712_03740   Burkholderia gladioli pv. gladioli FDAARGOS_389 ATF84254.1    
 CEJ98_10190   Burkholderia gladioli pv. gladioli KACC 11889 ASD79344.1    
 bglu_2g05460   Burkholderia glumae BGR1 ACR30989.1 C5AMD8  
 KS03_5368   Burkholderia glumae LMG 2196 = ATCC 33617 AJY63262.1    
 BG99_2085 (fragment)   Burkholderia mallei 11 AJX42992.1    
 BG99_2085 (fragment)   Burkholderia mallei 11 AJX42992.1    
 BG99_4947   Burkholderia mallei 11 AJX46705.1    
 BG99_4947   Burkholderia mallei 11 AJX46705.1    
 DM57_07660   Burkholderia mallei 2000031063 AIW47913.1    
 DM57_07660   Burkholderia mallei 2000031063 AIW47913.1    
 BO07_1954 (fragment)   Burkholderia mallei 2002721276 AJY33789.1    
 BO07_1954 (fragment)   Burkholderia mallei 2002721276 AJY33789.1    
 BO07_4802   Burkholderia mallei 2002721276 AJY36268.1    
 BO07_4802   Burkholderia mallei 2002721276 AJY36268.1    
 BM45_1959 (fragment)   Burkholderia mallei 2002734299 AJX02157.1    
 BM45_1959 (fragment)   Burkholderia mallei 2002734299 AJX02157.1    
 BM45_4017   Burkholderia mallei 2002734299 AJX05076.1    
 BM45_4017   Burkholderia mallei 2002734299 AJX05076.1    
 BO06_4075   Burkholderia mallei 2002734306 AJX55375.1    
 BO06_4075   Burkholderia mallei 2002734306 AJX55375.1    
 BO06_6 (fragment)   Burkholderia mallei 2002734306 AJX53035.1    
 BO06_6 (fragment)   Burkholderia mallei 2002734306 AJX53035.1    
 DM55_2815 (fragment)   Burkholderia mallei 23344 AIO52293.1    
 DM55_2815 (fragment)   Burkholderia mallei 23344 AIO52293.1    
 DM55_3242   Burkholderia mallei 23344 AIO54930.1    
 DM55_3242   Burkholderia mallei 23344 AIO54930.1    
 BMAA1664   Burkholderia mallei ATCC 23344 AAU45917.1    
 BMAA1664   Burkholderia mallei ATCC 23344 AAU45917.1    
 BMA0847   Burkholderia mallei ATCC 23344 AAU49138.1    
 BHL98_17835 (fragment)   Burkholderia mallei Bahrain1 AOP66796.1    
 BHL98_17835 (fragment)   Burkholderia mallei Bahrain1 AOP66796.1    
 BHL98_02085   Burkholderia mallei Bahrain1 AOP68710.1    
 BHL98_02085   Burkholderia mallei Bahrain1 AOP68710.1    
 DM57_4449   Burkholderia mallei BMK AIO78542.1    
 DM57_4449   Burkholderia mallei BMK AIO78542.1    
 DM57_2911 (fragment)   Burkholderia mallei BMK AIO81834.1    
 DM57_2911 (fragment)   Burkholderia mallei BMK AIO81834.1    
 DM76_2798 (fragment)   Burkholderia mallei BMQ AIO62041.1    
 DM76_2798 (fragment)   Burkholderia mallei BMQ AIO62041.1    
 DM76_3940   Burkholderia mallei BMQ AIO61293.1    
 DM76_3940   Burkholderia mallei BMQ AIO61293.1    
 DM78_4172   Burkholderia mallei BMY AIO55417.1    
 DM78_4172   Burkholderia mallei BMY AIO55417.1    
 RY28_18230   Burkholderia mallei FMH ATE34673.1    
 RY28_18230   Burkholderia mallei FMH ATE34673.1    
 RY28_04045   Burkholderia mallei FMH ATE31932.1    
 RY28_04045   Burkholderia mallei FMH ATE31932.1    
 DM51_610 (fragment)   Burkholderia mallei FMH 23344 AIP76117.1    
 DM51_610 (fragment)   Burkholderia mallei FMH 23344 AIP76117.1    
 DM51_3360   Burkholderia mallei FMH 23344 AIP73371.1    
 DM51_3360   Burkholderia mallei FMH 23344 AIP73371.1    
 BM47_4018   Burkholderia mallei India86-567-2 AJX51952.1    
 BM47_4018   Burkholderia mallei India86-567-2 AJX51952.1    
 BM47_2126 (fragment)   Burkholderia mallei India86-567-2 AJX49724.1    
 BM47_2126 (fragment)   Burkholderia mallei India86-567-2 AJX49724.1    
 RY29_04020   Burkholderia mallei JHU ATE36900.1    
 RY29_04020   Burkholderia mallei JHU ATE36900.1    
 RY29_18195   Burkholderia mallei JHU ATE39635.1    
 RY29_18195   Burkholderia mallei JHU ATE39635.1    
 BM94_3579   Burkholderia mallei KC_1092 AJX65837.1    
 BM94_3579   Burkholderia mallei KC_1092 AJX65837.1    
 BM94_2235 (fragment)   Burkholderia mallei KC_1092 AJX64716.1    
 BM94_2235 (fragment)   Burkholderia mallei KC_1092 AJX64716.1    
 BMA10299_1921   Burkholderia mallei NCTC 10229 ABM99806.1
ABM99018.2
A2S198
A2S199
 
 BMA10299_1921   Burkholderia mallei NCTC 10229 ABM99806.1
ABM99018.2
A2S198
A2S199
 
 BMA10299_A0506   Burkholderia mallei NCTC 10229 ABN01297.1 A2S3I5  
 BMA10299_A0506   Burkholderia mallei NCTC 10229 ABN01297.1 A2S3I5  
 BMA10247_A0596   Burkholderia mallei NCTC 10247 ABO03150.1 A3MC11  
 BMA10247_A0596   Burkholderia mallei NCTC 10247 ABO03150.1 A3MC11  
 BMA10247_0650 (fragment)   Burkholderia mallei NCTC 10247 ABO05596.1 A3MIY1  
 BMA10247_0650 (fragment)   Burkholderia mallei NCTC 10247 ABO05596.1 A3MIY1  
 BM44_3178   Burkholderia mallei NCTC 10247 AIS25870.1    
 BM44_3178   Burkholderia mallei NCTC 10247 AIS25870.1    
 BM44_2394 (fragment)   Burkholderia mallei NCTC 10247 AIS28575.1    
 BM44_2394 (fragment)   Burkholderia mallei NCTC 10247 AIS28575.1    
 BMASAVP1_1713   Burkholderia mallei SAVP1 ABM48230.1 A1UZA4  
 BMASAVP1_1713   Burkholderia mallei SAVP1 ABM48230.1 A1UZA4  
 BMASAVP1_A1368   Burkholderia mallei SAVP1 ABM52922.1 A1V397  
 NM78_08690   Burkholderia mallei Turkey1 ATD89056.1    
 NM78_08690   Burkholderia mallei Turkey1 ATD89056.1    
 NM78_18305   Burkholderia mallei Turkey1 ATD90949.1    
 NM78_18305   Burkholderia mallei Turkey1 ATD90949.1    
 NW99_23405   Burkholderia mallei Turkey10 ATE45434.1    
 NW99_23405   Burkholderia mallei Turkey10 ATE45434.1    
 NW99_09035   Burkholderia mallei Turkey10 ATE42714.1    
 NW99_09035   Burkholderia mallei Turkey10 ATE42714.1    
 NW91_22495   Burkholderia mallei Turkey2 ATD96446.1    
 NW91_22495   Burkholderia mallei Turkey2 ATD96446.1    
 NW91_08695   Burkholderia mallei Turkey2 ATD93815.1    
 NW91_08695   Burkholderia mallei Turkey2 ATD93815.1    
 NW92_23115   Burkholderia mallei Turkey3 ATE01305.1    
 NW92_23115   Burkholderia mallei Turkey3 ATE01305.1    
 NW92_09105   Burkholderia mallei Turkey3 ATD98627.1    
 NW92_09105   Burkholderia mallei Turkey3 ATD98627.1    
 NW93_23410   Burkholderia mallei Turkey4 ATE06224.1    
 NW93_23410   Burkholderia mallei Turkey4 ATE06224.1    
 NW93_09320   Burkholderia mallei Turkey4 ATE03535.1    
 NW93_09320   Burkholderia mallei Turkey4 ATE03535.1    
 NW94_23200   Burkholderia mallei Turkey5 ATE11097.1    
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