Carbohydrate-Binding Module Family 13

Activities in FamilyModules of approx. 150 residues which always appear as a threefold internal repeat. The only apparent exception to this, xylanase II of Actinomadura sp. FC7 (GenBank U08894), is in fact not completely sequenced. These modules were first identified in several plant lectins such as ricin or agglutinin of Ricinus communis which bind galactose residues. The three-dimensional structure of a plant lectin has been determined and displays a pseudo-threefold symmetry in accord with the observed sequence threefold repeat. These modules have since been found in a number of other proteins of various functions including glycoside hydrolases and glycosyltransferases. While in the plant lectins this module binds mannose, binding to xylan has been demonstrated in the Streptomyces lividans xylanase A and arabinofuranosidase B. Binding to GalNAc has been shown for the corresponding module of GalNAc transferase 4. For the other proteins, the binding specificity of these modules has not been established. The pseudo three-fold symmetry of the CBM13 module has now been confirmed in the 3-D structure of the intact, two-domain, xylanase of Streptomyces olivaceoviridis.
3D Structure Statusβ-trefoil
NotePreviously known as cellulose-binding domain family XIII (CBD XIII).
External resourcesHOMSTRAD;
Statistics GenBank accession (5533); Uniprot accession (902); PDB accession (143); 3D entries (56); cryst (1)
All (5278) Archaea (18) Bacteria (4665) Eukaryota (558) Viruses (26) unclassified (11) Structure (56 - 1 cryst) Characterized (99)
| 1 | ... | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | ... | 47 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 B7019_1983   Bifidobacterium breve JCM 7019 AHJ20146.1    
 B7019_1983   Bifidobacterium breve JCM 7019 AHJ20146.1    
 B7019_1983   Bifidobacterium breve JCM 7019 AHJ20146.1    
 BCOR_0219   Bifidobacterium coryneforme LMG18911 AII74239.1    
 BCOR_0219   Bifidobacterium coryneforme LMG18911 AII74239.1    
 BINDI_0153   Bifidobacterium indicum LMG 11587 = DSM 20214 AIC91439.1    
 BINDI_0153   Bifidobacterium indicum LMG 11587 = DSM 20214 AIC91439.1    
 BBKW_1752   Bifidobacterium kashiwanohense JCM 15439 = DSM 21854 BAQ29887.1    
 BBKW_1752   Bifidobacterium kashiwanohense JCM 15439 = DSM 21854 BAQ29887.1    
 BBKW_1752   Bifidobacterium kashiwanohense JCM 15439 = DSM 21854 BAQ29887.1    
 AH68_09395   Bifidobacterium kashiwanohense PV20-2 AIZ15211.1    
 AH68_09395   Bifidobacterium kashiwanohense PV20-2 AIZ15211.1    
 BL105A_1849   Bifidobacterium longum 105-A BAP84454.1    
 B624_1709   Bifidobacterium longum 35624 AOL11151.1    
 BBG7_1961   Bifidobacterium longum BG7 ALE37147.1    
 BBG7_1928   Bifidobacterium longum BG7 ALE37114.1    
 BBG7_1928   Bifidobacterium longum BG7 ALE37114.1    
 GS08_10135   Bifidobacterium longum BXY01 AIF91426.1    
 BLD_1519   Bifidobacterium longum DJO10A ACD98964.1    
 BL0157   Bifidobacterium longum NCC2705 AAN24012.1
NP_695376.1
Q8G7T8  
 SAMN04489749_0213   Bifidobacterium longum Su859 SDO32479.1    
 BLIF_1909   Bifidobacterium longum subsp. infantis 157F BAJ72043.1    
 BL1206_1978   Bifidobacterium longum subsp. longum AH1206 AOP02010.1    
 BBMN68_1454   Bifidobacterium longum subsp. longum BBMN68 ADQ02475.1 E4R242  
 BBL306_1413   Bifidobacterium longum subsp. longum CCUG30698 ALO74942.1    
 BLGT_09870   Bifidobacterium longum subsp. longum GT15 AIW44396.1    
 BLLJ_1841   Bifidobacterium longum subsp. longum JCM 1217 BAJ67505.1    
 BLJ_1955   Bifidobacterium longum subsp. longum JDM301 ADH01377.1 D6ZWX1  
 BLNIAS_00036   Bifidobacterium longum subsp. longum KACC 91563 AEI96592.1    
 B8809_1780   Bifidobacterium longum subsp. longum NCIMB8809 ALO73450.1    
 CGC63_01505   Blautia hansenii DSM 20583 ASM68290.1    
 SAMN05444159_0540   Bradyrhizobium lablabi GAS499 SHJ40954.1    
 S58_29670   Bradyrhizobium oligotrophicum S58 BAM88968.1    
 BRADO6329   Bradyrhizobium sp. ORS 278 CAL79964.1 A4Z1D8  
 EX87_22610 (fragment)   Brevibacillus laterosporus B9 AKF96321.1    
 EX87_22595   Brevibacillus laterosporus B9 AKF96318.1    
 EX87_22740   Brevibacillus laterosporus B9 AKF96340.1    
 BrL25_00800   Brevibacillus laterosporus DSM 25 ATO47770.1    
 BrL25_22225   Brevibacillus laterosporus DSM 25 ATO51571.1    
 BRLA_c029530 (Paga_1)   Brevibacillus laterosporus LMG 15441 AIG27265.1    
 BRLA_c029820 (Paga_2)   Brevibacillus laterosporus LMG 15441 AIG27294.1    
 P350_31615   Burkholderia cepacia JBK9 ALX16370.1    
 P350_31615   Burkholderia cepacia JBK9 ALX16370.1    
 P350_31615   Burkholderia cepacia JBK9 ALX16370.1    
 P350_31615   Burkholderia cepacia JBK9 ALX16370.1    
 BM43_3411   Burkholderia gladioli ATCC 10248 AJW98162.1    
 CO712_03740   Burkholderia gladioli pv. gladioli FDAARGOS_389 ATF84254.1    
 CEJ98_10190   Burkholderia gladioli pv. gladioli KACC 11889 ASD79344.1    
 bglu_2g05460   Burkholderia glumae BGR1 ACR30989.1 C5AMD8  
 KS03_5368   Burkholderia glumae LMG 2196 = ATCC 33617 AJY63262.1    
 BG99_2085 (fragment)   Burkholderia mallei 11 AJX42992.1    
 BG99_2085 (fragment)   Burkholderia mallei 11 AJX42992.1    
 BG99_4947   Burkholderia mallei 11 AJX46705.1    
 BG99_4947   Burkholderia mallei 11 AJX46705.1    
 DM57_07660   Burkholderia mallei 2000031063 AIW47913.1    
 DM57_07660   Burkholderia mallei 2000031063 AIW47913.1    
 BO07_1954 (fragment)   Burkholderia mallei 2002721276 AJY33789.1    
 BO07_1954 (fragment)   Burkholderia mallei 2002721276 AJY33789.1    
 BO07_4802   Burkholderia mallei 2002721276 AJY36268.1    
 BO07_4802   Burkholderia mallei 2002721276 AJY36268.1    
 BM45_1959 (fragment)   Burkholderia mallei 2002734299 AJX02157.1    
 BM45_1959 (fragment)   Burkholderia mallei 2002734299 AJX02157.1    
 BM45_4017   Burkholderia mallei 2002734299 AJX05076.1    
 BM45_4017   Burkholderia mallei 2002734299 AJX05076.1    
 BO06_4075   Burkholderia mallei 2002734306 AJX55375.1    
 BO06_4075   Burkholderia mallei 2002734306 AJX55375.1    
 BO06_6 (fragment)   Burkholderia mallei 2002734306 AJX53035.1    
 BO06_6 (fragment)   Burkholderia mallei 2002734306 AJX53035.1    
 DM55_2815 (fragment)   Burkholderia mallei 23344 AIO52293.1    
 DM55_2815 (fragment)   Burkholderia mallei 23344 AIO52293.1    
 DM55_3242   Burkholderia mallei 23344 AIO54930.1    
 DM55_3242   Burkholderia mallei 23344 AIO54930.1    
 BMAA1664   Burkholderia mallei ATCC 23344 AAU45917.1    
 BMAA1664   Burkholderia mallei ATCC 23344 AAU45917.1    
 BMA0847   Burkholderia mallei ATCC 23344 AAU49138.1    
 BHL98_17835 (fragment)   Burkholderia mallei Bahrain1 AOP66796.1    
 BHL98_17835 (fragment)   Burkholderia mallei Bahrain1 AOP66796.1    
 BHL98_02085   Burkholderia mallei Bahrain1 AOP68710.1    
 BHL98_02085   Burkholderia mallei Bahrain1 AOP68710.1    
 DM57_4449   Burkholderia mallei BMK AIO78542.1    
 DM57_4449   Burkholderia mallei BMK AIO78542.1    
 DM57_2911 (fragment)   Burkholderia mallei BMK AIO81834.1    
 DM57_2911 (fragment)   Burkholderia mallei BMK AIO81834.1    
 DM76_2798 (fragment)   Burkholderia mallei BMQ AIO62041.1    
 DM76_2798 (fragment)   Burkholderia mallei BMQ AIO62041.1    
 DM76_3940   Burkholderia mallei BMQ AIO61293.1    
 DM76_3940   Burkholderia mallei BMQ AIO61293.1    
 DM78_4172   Burkholderia mallei BMY AIO55417.1    
 DM78_4172   Burkholderia mallei BMY AIO55417.1    
 RY28_18230   Burkholderia mallei FMH ATE34673.1    
 RY28_18230   Burkholderia mallei FMH ATE34673.1    
 RY28_04045   Burkholderia mallei FMH ATE31932.1    
 RY28_04045   Burkholderia mallei FMH ATE31932.1    
 DM51_610 (fragment)   Burkholderia mallei FMH 23344 AIP76117.1    
 DM51_610 (fragment)   Burkholderia mallei FMH 23344 AIP76117.1    
 DM51_3360   Burkholderia mallei FMH 23344 AIP73371.1    
 DM51_3360   Burkholderia mallei FMH 23344 AIP73371.1    
 BM47_4018   Burkholderia mallei India86-567-2 AJX51952.1    
 BM47_4018   Burkholderia mallei India86-567-2 AJX51952.1    
 BM47_2126 (fragment)   Burkholderia mallei India86-567-2 AJX49724.1    
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