Carbohydrate-Binding Module Family 13

Activities in FamilyModules of approx. 150 residues which always appear as a threefold internal repeat. The only apparent exception to this, xylanase II of Actinomadura sp. FC7 (GenBank U08894), is in fact not completely sequenced. These modules were first identified in several plant lectins such as ricin or agglutinin of Ricinus communis which bind galactose residues. The three-dimensional structure of a plant lectin has been determined and displays a pseudo-threefold symmetry in accord with the observed sequence threefold repeat. These modules have since been found in a number of other proteins of various functions including glycoside hydrolases and glycosyltransferases. While in the plant lectins this module binds mannose, binding to xylan has been demonstrated in the Streptomyces lividans xylanase A and arabinofuranosidase B. Binding to GalNAc has been shown for the corresponding module of GalNAc transferase 4. For the other proteins, the binding specificity of these modules has not been established. The pseudo three-fold symmetry of the CBM13 module has now been confirmed in the 3-D structure of the intact, two-domain, xylanase of Streptomyces olivaceoviridis.
3D Structure Statusβ-trefoil
NotePreviously known as cellulose-binding domain family XIII (CBD XIII).
External resourcesHOMSTRAD;
Statistics GenBank accession (5533); Uniprot accession (902); PDB accession (143); 3D entries (56); cryst (1)
All (5278) Archaea (18) Bacteria (4665) Eukaryota (558) Viruses (26) unclassified (11) Structure (56 - 1 cryst) Characterized (99)
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | ... | 47 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 AcGH5 / AceceDRAFT_1592 3.2.1.- Acetivibrio cellulolyticus CD2 EFL62381.1 E1KC96  
 LuPra_05212 (Abn-ts_2)   Acidobacteria bacterium DSM 100886 AMY11942.1    
 ACP_0871   Acidobacterium capsulatum ATCC 51196 ACO32851.1 C1F2X0  
 C380_15030   Acidovorax sp. KKS102 AFU46703.1    
 AHTJS_06760   Acinetobacter haemolyticus TJS01 APR70108.1    
 AHOG_17785   Actinoalloteichus hoggarensis DSM 45943 ASO21182.1    
 AHOG_25390 (AbfB)   Actinoalloteichus hoggarensis DSM 45943 ASO22683.1    
 AHOG_22090   Actinoalloteichus hoggarensis DSM 45943 ASO22033.1    
 TL08_24460   Actinoalloteichus hymeniacidonis HPA177(T) (=DSM 45092(T)) AOS65670.1    
 UA74_19810   Actinoalloteichus sp. ADI127-7 APU15987.1    
 UA74_27530   Actinoalloteichus sp. ADI127-7 APU17509.1    
 UA75_28075   Actinoalloteichus sp. GBA129-24 APU23586.1    
 UA75_20310   Actinoalloteichus sp. GBA129-24 APU22051.1    
 ACEE_07815 (fragment)   Actinobacillus equuli subsp. equuli 19392 AIZ79674.1    
 CHY23_01064   Actinobacillus pleuropneumoniae KL 16 ASU15823.1    
 APJL_1995   Actinobacillus pleuropneumoniae serovar 3 str. JL03 ABY70543.1 B0BTX6  
 APL_1948   Actinobacillus pleuropneumoniae serovar 5b str. L20 ABN75026.1 A3N3P0  
 APP7_2036   Actinobacillus pleuropneumoniae serovar 7 str. AP76 ACE62688.1 B3H318  
 MIDG2331_02176   Actinobacillus pleuropneumoniae serovar 8 CUU53394.1    
 ASU1_07520   Actinobacillus suis ATCC 33415 AIJ31765.1    
 ASU2_07445   Actinobacillus suis H91-0380 AFU19627.1    
 SAMEA4504061_01576   Actinobacillus suis NCTC12996 SNV36070.1    
 xylanase II (XylII) (fragment) 3.2.1.8 Actinomadura sp. FC7 AAA17888.1
AAO97631.1
AAQ80272.1
Q59139  
 actinohivin (Ath)   actinomycete K97-0003 BAA97578.1
AAN99135.1
Q9KWN0 3A07[A,B]
4DEN[A]
4END[A]
4G1R[A,C]
4G1S[A]
4P6A[A]
 SAMN04489716_4359   Actinoplanes derwentensis DSM 43941 SDT53506.1    
 SAMN04489716_2149   Actinoplanes derwentensis DSM 43941 SDS97814.1    
 SAMN04489716_7045   Actinoplanes derwentensis DSM 43941 SDT74640.1    
 SAMN04489716_3019   Actinoplanes derwentensis DSM 43941 SDT25471.1    
 SAMN04489716_9061   Actinoplanes derwentensis DSM 43941 SDT80101.1    
 SAMN04489716_4630   Actinoplanes derwentensis DSM 43941 SDT57818.1    
 SAMN04489716_4358   Actinoplanes derwentensis DSM 43941 SDT53490.1    
 SAMN04489716_2150   Actinoplanes derwentensis DSM 43941 SDS97841.1    
 SAMN04489716_9542   Actinoplanes derwentensis DSM 43941 SDT81215.1    
 SAMN04489716_9542   Actinoplanes derwentensis DSM 43941 SDT81215.1    
 SAMN04489716_2875   Actinoplanes derwentensis DSM 43941 SDT21472.1    
 SAMN04489716_9606   Actinoplanes derwentensis DSM 43941 SDT81378.1    
 SAMN04489716_8791   Actinoplanes derwentensis DSM 43941 SDT79450.1    
 SAMN04489716_4356   Actinoplanes derwentensis DSM 43941 SDT53467.1    
 SAMN04489716_3154   Actinoplanes derwentensis DSM 43941 SDT29034.1    
 SAMN04489716_0823   Actinoplanes derwentensis DSM 43941 SDS45579.1    
 SAMN04489716_3389   Actinoplanes derwentensis DSM 43941 SDT34677.1    
 SAMN04489716_2838   Actinoplanes derwentensis DSM 43941 SDT20333.1    
 SAMN04489716_5669   Actinoplanes derwentensis DSM 43941 SDT68742.1    
 SAMN04489716_4520   Actinoplanes derwentensis DSM 43941 SDT56085.1    
 SAMN04489716_5361   Actinoplanes derwentensis DSM 43941 SDT66543.1    
 SAMN04489716_1072   Actinoplanes derwentensis DSM 43941 SDS56728.1    
 SAMN04489716_2952   Actinoplanes derwentensis DSM 43941 SDT23632.1    
 SAMN04489716_2820   Actinoplanes derwentensis DSM 43941 SDT19755.1    
 SAMN04489716_2359   Actinoplanes derwentensis DSM 43941 SDT04936.1    
 SAMN04489716_1514   Actinoplanes derwentensis DSM 43941 SDS74768.1    
 SAMN04489716_1906   Actinoplanes derwentensis DSM 43941 SDS89210.1    
 SAMN04489716_2458   Actinoplanes derwentensis DSM 43941 SDT08346.1    
 SAMN04489716_5668   Actinoplanes derwentensis DSM 43941 SDT68735.1    
 SAMN04489716_9062   Actinoplanes derwentensis DSM 43941 SDT80103.1    
 SAMN04489716_2360   Actinoplanes derwentensis DSM 43941 SDT04982.1    
 SAMN04489716_1299   Actinoplanes derwentensis DSM 43941 SDS66128.1    
 AFR_01180   Actinoplanes friuliensis DSM 7358 AGZ38525.1    
 AFR_01605   Actinoplanes friuliensis DSM 7358 AGZ38610.1    
 AFR_03690   Actinoplanes friuliensis DSM 7358 AGZ39027.1    
 AFR_03705   Actinoplanes friuliensis DSM 7358 AGZ39030.1    
 AFR_04300   Actinoplanes friuliensis DSM 7358 AGZ39149.1    
 AFR_08740   Actinoplanes friuliensis DSM 7358 AGZ40037.1    
 AFR_12555   Actinoplanes friuliensis DSM 7358 AGZ40797.1    
 AFR_12835   Actinoplanes friuliensis DSM 7358 AGZ40853.1    
 AFR_14330   Actinoplanes friuliensis DSM 7358 AGZ41148.1    
 AFR_14770   Actinoplanes friuliensis DSM 7358 AGZ41236.1    
 AFR_15480   Actinoplanes friuliensis DSM 7358 AGZ41378.1    
 AFR_15820   Actinoplanes friuliensis DSM 7358 AGZ41446.1    
 AFR_16445   Actinoplanes friuliensis DSM 7358 AGZ41571.1    
 AFR_17060   Actinoplanes friuliensis DSM 7358 AGZ41690.1    
 AFR_17540   Actinoplanes friuliensis DSM 7358 AGZ41786.1    
 AFR_17865   Actinoplanes friuliensis DSM 7358 AGZ41851.1    
 AFR_18830   Actinoplanes friuliensis DSM 7358 AGZ42042.1    
 AFR_22100   Actinoplanes friuliensis DSM 7358 AGZ42690.1    
 AFR_23400   Actinoplanes friuliensis DSM 7358 AGZ42950.1    
 AFR_25380   Actinoplanes friuliensis DSM 7358 AGZ43340.1    
 AFR_28485   Actinoplanes friuliensis DSM 7358 AGZ43958.1    
 AFR_28490   Actinoplanes friuliensis DSM 7358 AGZ43959.1    
 AFR_29160   Actinoplanes friuliensis DSM 7358 AGZ44093.1    
 AFR_29165   Actinoplanes friuliensis DSM 7358 AGZ44094.1    
 AFR_29170   Actinoplanes friuliensis DSM 7358 AGZ44095.1    
 AFR_29180   Actinoplanes friuliensis DSM 7358 AGZ44097.1    
 AFR_29190   Actinoplanes friuliensis DSM 7358 AGZ44099.1    
 AFR_29205   Actinoplanes friuliensis DSM 7358 AGZ44102.1    
 AFR_29210   Actinoplanes friuliensis DSM 7358 AGZ44103.1    
 AFR_32520   Actinoplanes friuliensis DSM 7358 AGZ44762.1    
 AFR_38190   Actinoplanes friuliensis DSM 7358 AGZ45892.1    
 AFR_39015   Actinoplanes friuliensis DSM 7358 AGZ46057.1    
 AFR_41225   Actinoplanes friuliensis DSM 7358 AGZ46499.1    
 AFR_42305   Actinoplanes friuliensis DSM 7358 AGZ46715.1    
 AFR_12840   Actinoplanes friuliensis DSM 7358 AGZ40854.1    
 AFR_14980   Actinoplanes friuliensis DSM 7358 AGZ41278.1    
 AFR_17105   Actinoplanes friuliensis DSM 7358 AGZ41699.1    
 AFR_21985   Actinoplanes friuliensis DSM 7358 AGZ42667.1    
 AFR_27820   Actinoplanes friuliensis DSM 7358 AGZ43825.1    
 AFR_29175   Actinoplanes friuliensis DSM 7358 AGZ44096.1    
 AFR_29195   Actinoplanes friuliensis DSM 7358 AGZ44100.1    
 AFR_29200   Actinoplanes friuliensis DSM 7358 AGZ44101.1    
 AFR_31185   Actinoplanes friuliensis DSM 7358 AGZ44497.1    
 AFR_32590   Actinoplanes friuliensis DSM 7358 AGZ44776.1    
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