Carbohydrate-Binding Module Family 13

Activities in FamilyModules of approx. 150 residues which always appear as a threefold internal repeat. The only apparent exception to this, xylanase II of Actinomadura sp. FC7 (GenBank U08894), is in fact not completely sequenced. These modules were first identified in several plant lectins such as ricin or agglutinin of Ricinus communis which bind galactose residues. The three-dimensional structure of a plant lectin has been determined and displays a pseudo-threefold symmetry in accord with the observed sequence threefold repeat. These modules have since been found in a number of other proteins of various functions including glycoside hydrolases and glycosyltransferases. While in the plant lectins this module binds mannose, binding to xylan has been demonstrated in the Streptomyces lividans xylanase A and arabinofuranosidase B. Binding to GalNAc has been shown for the corresponding module of GalNAc transferase 4. For the other proteins, the binding specificity of these modules has not been established. The pseudo three-fold symmetry of the CBM13 module has now been confirmed in the 3-D structure of the intact, two-domain, xylanase of Streptomyces olivaceoviridis.
3D Structure Statusβ-trefoil
NotePreviously known as cellulose-binding domain family XIII (CBD XIII).
External resourcesHOMSTRAD;
Statistics GenBank accession (5439); Uniprot accession (902); PDB accession (142); 3D entries (56); cryst (1)
All (5178) Archaea (18) Bacteria (4566) Eukaryota (557) Viruses (26) unclassified (11) Structure (56 - 1 cryst) Characterized (99)
| 1 | ... | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | ... | 46 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 A9498_31550   Bacillus thuringiensis serovar coreanensis ST7 ANN35896.1    
 A9498_28915   Bacillus thuringiensis serovar coreanensis ST7 ANN35453.1    
 A9498_29535   Bacillus thuringiensis serovar coreanensis ST7 ANN35658.1    
 A9498_29550   Bacillus thuringiensis serovar coreanensis ST7 ANN35547.1    
 PBt054   Bacillus thuringiensis serovar israelensis CAD30104.1 Q8KNU9  
 PBt054   Bacillus thuringiensis serovar israelensis CAD30104.1 Q8KNU9  
 PBt152   Bacillus thuringiensis serovar israelensis CAD30184.1 Q8KNP4  
 ORF   Bacillus thuringiensis serovar israelensis 1.24 ASO64511.1    
 ORF   Bacillus thuringiensis serovar israelensis 1.24 ASO64511.1    
 hemagglutinin-related protein (plasmid)   Bacillus thuringiensis serovar israelensis 1.24 ASO64578.1    
 ATN07_33745   Bacillus thuringiensis serovar israelensis AM65-52 AND28683.1    
 ATN07_33745   Bacillus thuringiensis serovar israelensis AM65-52 AND28683.1    
 ATN07_33560   Bacillus thuringiensis serovar israelensis AM65-52 AND28648.1    
 ATN07_34550   Bacillus thuringiensis serovar israelensis AM65-52 AND28830.1    
 ATN07_29875   Bacillus thuringiensis serovar israelensis AM65-52 APF32705.1    
 toxin (plasmid)   Bacillus thuringiensis serovar israelensis HD522 BAV56204.1    
 toxin (plasmid)   Bacillus thuringiensis serovar israelensis HD522 BAV56204.1    
 BG08_6214   Bacillus thuringiensis serovar kurstaki HD 1 AJK37933.1    
 BTK_31084   Bacillus thuringiensis serovar kurstaki str. HD-1 AIE37804.1    
 DF16_pBMB400orf00380   Bacillus thuringiensis serovar kurstaki str. YBT-1520 AIM35215.1    
 YBT1520_31234   Bacillus thuringiensis serovar kurstaki str. YBT-1520 AHZ54746.1    
 KNN_06946   Bacillus thuringiensis serovar tolworthi Pasteur Institute Standard strain BAR87679.1    
 insecticidal crystal protein 6   Bacillus thuringiensis SK700 AJW76687.1    
 insecticidal crystal protein 6   Bacillus thuringiensis SK700 AJW76687.1    
 XI92_29830   Bacillus thuringiensis YC-10 AKJ62375.1    
 CHH28_07170   Bacterioplanes sanyensis NV9 ASP38465.1    
 CHH28_07310   Bacterioplanes sanyensis NV9 ASP38492.1    
 BcellWH2_02913 (Abn-ts_3)   Bacteroides cellulosilyticus WH2 ALJ60152.1    
 BcellWH2_02970   Bacteroides cellulosilyticus WH2 ALJ60208.1    
 AB656_00595   Bifidobacterium actinocoloniiforme DSM 22766 AKV55018.1    
 BADO_1512   Bifidobacterium adolescentis 22L AII76920.1    
 BADO_1512   Bifidobacterium adolescentis 22L AII76920.1    
 BADO_1512   Bifidobacterium adolescentis 22L AII76920.1    
 BBMN23_1664   Bifidobacterium adolescentis BBMN23 AJE06636.1    
 BBMN23_1664   Bifidobacterium adolescentis BBMN23 AJE06636.1    
 BBMN23_1664   Bifidobacterium adolescentis BBMN23 AJE06636.1    
 Bang102_001540   Bifidobacterium angulatum GT102 AMK57293.1    
 Bang102_001540   Bifidobacterium angulatum GT102 AMK57293.1    
 Bang102_001540   Bifidobacterium angulatum GT102 AMK57293.1    
 BBBF_0047   Bifidobacterium bifidum ATCC 29521 = JCM 1255 = DSM 20456 BAQ97254.1    
 BBBF_0047   Bifidobacterium bifidum ATCC 29521 = JCM 1255 = DSM 20456 BAQ97254.1    
 BBBF_0047   Bifidobacterium bifidum ATCC 29521 = JCM 1255 = DSM 20456 BAQ97254.1    
 RY70_101   Bifidobacterium bifidum BF3 ALE10489.1    
 RY70_101   Bifidobacterium bifidum BF3 ALE10489.1    
 RY70_101   Bifidobacterium bifidum BF3 ALE10489.1    
 BBB_0050 (LytC)   Bifidobacterium bifidum BGN4 AFL03647.1    
 BBB_0050 (LytC)   Bifidobacterium bifidum BGN4 AFL03647.1    
 BBB_0050 (LytC)   Bifidobacterium bifidum BGN4 AFL03647.1    
 BBJK_01493 (LytC)   Bifidobacterium bifidum LMG 13195 JCM 7004 BBA48030.1    
 BBJK_01493 (LytC)   Bifidobacterium bifidum LMG 13195 JCM 7004 BBA48030.1    
 BBJK_01493 (LytC)   Bifidobacterium bifidum LMG 13195 JCM 7004 BBA48030.1    
 BBPR_0052   Bifidobacterium bifidum PRL2010 ADP35190.1 E4NY16  
 BBPR_0052   Bifidobacterium bifidum PRL2010 ADP35190.1 E4NY16  
 BBPR_0052   Bifidobacterium bifidum PRL2010 ADP35190.1 E4NY16  
 BBIF_0048 (LytC)   Bifidobacterium bifidum S17 ADO52253.1 E3ENH5  
 BBIF_0048 (LytC)   Bifidobacterium bifidum S17 ADO52253.1 E3ENH5  
 BBIF_0048 (LytC)   Bifidobacterium bifidum S17 ADO52253.1 E3ENH5  
 B7019_1983   Bifidobacterium breve JCM 7019 AHJ20146.1    
 B7019_1983   Bifidobacterium breve JCM 7019 AHJ20146.1    
 B7019_1983   Bifidobacterium breve JCM 7019 AHJ20146.1    
 BCOR_0219   Bifidobacterium coryneforme LMG18911 AII74239.1    
 BCOR_0219   Bifidobacterium coryneforme LMG18911 AII74239.1    
 BINDI_0153   Bifidobacterium indicum LMG 11587 = DSM 20214 AIC91439.1    
 BINDI_0153   Bifidobacterium indicum LMG 11587 = DSM 20214 AIC91439.1    
 BBKW_1752   Bifidobacterium kashiwanohense JCM 15439 = DSM 21854 BAQ29887.1    
 BBKW_1752   Bifidobacterium kashiwanohense JCM 15439 = DSM 21854 BAQ29887.1    
 BBKW_1752   Bifidobacterium kashiwanohense JCM 15439 = DSM 21854 BAQ29887.1    
 AH68_09395   Bifidobacterium kashiwanohense PV20-2 AIZ15211.1    
 AH68_09395   Bifidobacterium kashiwanohense PV20-2 AIZ15211.1    
 BL105A_1849   Bifidobacterium longum 105-A BAP84454.1    
 B624_1709   Bifidobacterium longum 35624 AOL11151.1    
 BBG7_1961   Bifidobacterium longum BG7 ALE37147.1    
 BBG7_1928   Bifidobacterium longum BG7 ALE37114.1    
 BBG7_1928   Bifidobacterium longum BG7 ALE37114.1    
 GS08_10135   Bifidobacterium longum BXY01 AIF91426.1    
 BLD_1519   Bifidobacterium longum DJO10A ACD98964.1    
 BL0157   Bifidobacterium longum NCC2705 AAN24012.1
NP_695376.1
Q8G7T8  
 SAMN04489749_0213   Bifidobacterium longum Su859 SDO32479.1    
 BLIF_1909   Bifidobacterium longum subsp. infantis 157F BAJ72043.1    
 BL1206_1978   Bifidobacterium longum subsp. longum AH1206 AOP02010.1    
 BBMN68_1454   Bifidobacterium longum subsp. longum BBMN68 ADQ02475.1 E4R242  
 BBL306_1413   Bifidobacterium longum subsp. longum CCUG30698 ALO74942.1    
 BLGT_09870   Bifidobacterium longum subsp. longum GT15 AIW44396.1    
 BLLJ_1841   Bifidobacterium longum subsp. longum JCM 1217 BAJ67505.1    
 BLJ_1955   Bifidobacterium longum subsp. longum JDM301 ADH01377.1 D6ZWX1  
 BLNIAS_00036   Bifidobacterium longum subsp. longum KACC 91563 AEI96592.1    
 B8809_1780   Bifidobacterium longum subsp. longum NCIMB8809 ALO73450.1    
 CGC63_01505   Blautia hansenii DSM 20583 ASM68290.1    
 SAMN05444159_0540   Bradyrhizobium lablabi GAS499 SHJ40954.1    
 S58_29670   Bradyrhizobium oligotrophicum S58 BAM88968.1    
 BRADO6329   Bradyrhizobium sp. ORS 278 CAL79964.1 A4Z1D8  
 EX87_22610 (fragment)   Brevibacillus laterosporus B9 AKF96321.1    
 EX87_22595   Brevibacillus laterosporus B9 AKF96318.1    
 EX87_22740   Brevibacillus laterosporus B9 AKF96340.1    
 BRLA_c029530 (Paga_1)   Brevibacillus laterosporus LMG 15441 AIG27265.1    
 BRLA_c029820 (Paga_2)   Brevibacillus laterosporus LMG 15441 AIG27294.1    
 P350_31615   Burkholderia cepacia JBK9 ALX16370.1    
 P350_31615   Burkholderia cepacia JBK9 ALX16370.1    
 P350_31615   Burkholderia cepacia JBK9 ALX16370.1    
 P350_31615   Burkholderia cepacia JBK9 ALX16370.1    
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