Glycoside Hydrolase Family 84

Activities in FamilyN-acetyl β-glucosaminidase (EC 3.2.1.52); hyaluronidase (EC 3.2.1.35); [protein]-3-O-(GlcNAc)-L-Ser/Thr β-N-acetylglucosaminidase (EC 3.2.1.169)
Mechanism Retaining
3D Structure Status( β / α ) 8
Catalytic Nucleophile/Basecarbonyl oxygen of C-2 acetamido group of substrate
Catalytic Proton DonorAsp
NoteMechanism shown in Macauley et al. (2005) JBC 280:25313-25322
External resourcesCAZypedia;
Commercial Enzyme Provider(s)PROZOMIX;
Statistics GenBank accession (680); Uniprot accession (107); PDB accession (59); 3D entries (6); cryst (0)
| 1 | 2 | 3 | 4 | 5 | 6 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 SAM23877_2700   Streptomyces ambofaciens ATCC 23877 AKZ55749.1    
 SAM23877_1062   Streptomyces ambofaciens ATCC 23877 AKZ54111.1    
 SAML0971   Streptomyces ambofaciens ATCC 23877 CAJ89957.1 A3KJS2  
 SAM40697_2476   Streptomyces ambofaciens DSM 40697 ANB06435.1    
 SAM40697_0930   Streptomyces ambofaciens DSM 40697 ANB04891.1    
 BV401_16825   Streptomyces autolyticus CGMCC0516 AQA11885.1    
 BV401_05140   Streptomyces autolyticus CGMCC0516 AQA09972.1    
 SBI_00159   Streptomyces bingchenggensis BCW-1 ADI03280.1 D7BUT9  
 SBI_07080   Streptomyces bingchenggensis BCW-1 ADI10200.1 D7C3H5  
 TU94_11620   Streptomyces cyaneogriseus subsp. noncyanogenus NMWT 1 AJP02049.1    
 SFUL_2231   Streptomyces fulvissimus DSM 40593 AGK77186.1    
 B1H19_15215   Streptomyces gilvosporeus F607 ARF55359.1    
 SGLAU_12155   Streptomyces glaucescens GLA.O AIR98428.1    
 WQO_11075   Streptomyces globisporus C-1027 ALU93848.1    
 SGR_4877   Streptomyces griseus subsp. griseus NBRC 13350 BAG21706.1 B1VX60  
 SHXM_04285   Streptomyces hygroscopicus XM201 AQW50822.1    
 SHXM_00809   Streptomyces hygroscopicus XM201 AQW47346.1    
 SHXM_09497   Streptomyces hygroscopicus XM201 AQW56034.1    
 SIRAN9180   Streptomyces iranensis CDR16919.1    
 SIRAN6412   Streptomyces iranensis CDR09818.1    
 SLA_2333   Streptomyces laurentii ATCC 31255 BAU83261.1    
 Sle_45640   Streptomyces leeuwenhoekii C34 (= DSM 42122 = NRRL B-24963) CQR64022.1    
 SLINC_6481   Streptomyces lincolnensis NRRL 2936 ANS68705.1    
 SL103_05840   Streptomyces lydicus 103 AOP45824.1    
 SL103_25090   Streptomyces lydicus 103 AOP49085.1    
 BBN63_23315   Streptomyces niveus SCSIO 3406 AQU68689.1    
 SNOUR_11055   Streptomyces noursei ATCC 11455 ANZ15525.1    
 SNOUR_27095   Streptomyces noursei ATCC 11455 ANZ18673.1    
 B1H29_24135   Streptomyces pactum ACT12 AQS72201.1    
 Sfla_1448   Streptomyces pratensis ATCC 33331 ADW02888.1 C9ND52  
 Sfla_4228   Streptomyces pratensis ATCC 33331 ADW05636.1 C9NFQ2  
 SPRI_4862   Streptomyces pristinaespiralis HCCB 10218 ALC23168.1    
 SPRI_1498   Streptomyces pristinaespiralis HCCB 10218 ALC19804.1    
 M271_31960   Streptomyces rapamycinicus NRRL 5491 AGP57818.1    
 M271_46640   Streptomyces rapamycinicus NRRL 5491 AGP60691.1    
 A4G23_01727 (NagJ)   Streptomyces rubrolavendulae MJM4426 AOT58904.1    
 A7J05_23755   Streptomyces silaceus ACCC40021 APY88300.1    
 CGL27_17860   Streptomyces sp. 11-1-2 ASQ94684.1    
 CGL27_04195   Streptomyces sp. 11-1-2 ASQ92465.1    
 SAMN06272775_1257   Streptomyces sp. 2323.1 SOE10206.1    
 SAMN06272775_0353   Streptomyces sp. 2323.1 SOE09262.1    
 SAMN06272775_4687   Streptomyces sp. 2323.1 SOE13712.1    
 ASR50_12850   Streptomyces sp. 4F ALV50208.1    
 GZL_01022   Streptomyces sp. 769 AJC53626.1    
 GZL_02592   Streptomyces sp. 769 AJC55181.1    
 GZL_05761   Streptomyces sp. 769 AJC58336.1    
 T261_5410   Streptomyces sp. A02 AJT67035.3
AJT67035.1
AJT67035.2
   
 T261_1828   Streptomyces sp. A02 AJT63513.1    
 NI25_36120   Streptomyces sp. CCM_MD2014 AIV38295.1    
 ABE83_24825   Streptomyces sp. CFMR 7 ALC29914.1    
 AA958_09820   Streptomyces sp. CNQ-509 AKH82480.1    
 AA958_28465   Streptomyces sp. CNQ-509 AKH85523.1    
 B1K54_13385   Streptomyces sp. fd1-xmd AQT72538.1    
 SFR_5038   Streptomyces sp. FR-008 ALM41653.1    
 SFR_2645   Streptomyces sp. FR-008 ALM39260.1    
 M444_12985   Streptomyces sp. Mg1 AKL66173.1    
 STRMOE7_14050   Streptomyces sp. MOE7 ARH95271.1    
 F750_5429   Streptomyces sp. PAMC 26508 AGJ57858.1    
 F750_2484   Streptomyces sp. PAMC 26508 AGJ54970.1    
 A4E84_13980   Streptomyces sp. S10(2016) AMW10523.1    
 A6E92_21715   Streptomyces sp. S8 ARI54491.1    
 B6R96_23165   Streptomyces sp. Sge12 ARE76488.1    
 SACTE_2080   Streptomyces sp. SirexAA-E AEN09981.1    
 SAMN05216371_2596   Streptomyces sp. TLI_053 SDT50703.1    
 BSL84_11585   Streptomyces sp. TN58 APU40312.1    
 TK78_23700   Streptomyces sp. Tue 6075 Tue6075 APS21586.1    
 SVEN_2438   Streptomyces venezuelae ATCC 10712 CCA55724.1    
 BN2537_6671   Streptomyces venezuelae ATCC 15439 CUM38853.1    
 BN2537_11271   Streptomyces venezuelae ATCC 15439 CUM41153.1    
 AQF52_2891   Streptomyces venezuelae ATCC 15439 ALO08485.1    
 AQF52_5075   Streptomyces venezuelae ATCC 15439 ALO10669.1    
 B1H20_10320   Streptomyces violaceoruber S21 ARF66111.1    
 Strvi_5205   Streptomyces violaceusniger Tu 4113 AEM84739.1    
 Strvi_7941   Streptomyces violaceusniger Tu 4113 AEM87264.1    
 Tsac_2289   Thermoanaerobacterium saccharolyticum JW/SL-YS485 AFK87293.1    
 SAMN05660242_2297   Thermoanaerobacterium sp. RBIITD SNX54593.1    
 Thethe_01898   Thermoanaerobacterium thermosaccharolyticum M0795 AGB19509.1    
 Thert_00287   Thermoanaerobacterium thermosaccharolyticum TG57 AST56509.1    
 Tter_0116   Thermobaculum terrenum ATCC BAA-798 ACZ41038.1 D1CDN2 5DIY[A,B]
 CIG75_10185   Tumebacillus algifaecis THMBR28 ASS75322.1    
 CBW65_12910   Tumebacillus sp. AR23208 ARU61830.1    
 CBW65_19250   Tumebacillus sp. AR23208 ARU62875.1    
 β-N-acetylglucosaminidase (fragment)   uncultured bacterium APO31996.1    
 β-N-acetylglucosaminidase family protein   uncultured bacterium 4L05 ALB75783.1    
 ORF_27c   uncultured gamma proteobacterium HF0770_09E07 ADI23125.1    
 BME96_15585   Virgibacillus halodenitrificans PDB-F2 APC49528.1    
 BME96_15590   Virgibacillus halodenitrificans PDB-F2 APC49529.1    
 BME96_14800   Virgibacillus halodenitrificans PDB-F2 APC49382.1    
 CFK40_05195   Virgibacillus necropolis LMG 19488 ASN07301.1    
 CFK37_09225   Virgibacillus sp. LM2416 ASK62324.1    
 CFK37_08530   Virgibacillus sp. LM2416 ASK62202.1    
 CFK37_10320   Virgibacillus sp. LM2416 ASK64369.1    
 AKJ12_21630   Xanthomonas arboricola pv. juglandis Xaj 417 AKU52092.1    
 XAC3928   Xanthomonas axonopodis pv. citri str. 306 AAM38765.1
NP_644229.1
Q8PFQ0  
 XACM_3822   Xanthomonas axonopodis pv. citrumelo F1 AEO44061.1    
 XAC29_19935   Xanthomonas axonopodis Xac29-1 AGH79380.1    
 XB05_14600   Xanthomonas campestris 17 AKC79853.1    
 AAW18_10085   Xanthomonas campestris pv. campestris 17 ALE68783.1    
 AEA01_10425   Xanthomonas campestris pv. campestris 4013 AKS20306.1    
 AEA00_10300   Xanthomonas campestris pv. campestris ICMP 21080 AKS16282.1    
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