Glycoside Hydrolase Family 84

Activities in FamilyN-acetyl β-glucosaminidase (EC 3.2.1.52); hyaluronidase (EC 3.2.1.35); [protein]-3-O-(GlcNAc)-L-Ser/Thr β-N-acetylglucosaminidase (EC 3.2.1.169)
Mechanism Retaining
3D Structure Status( β / α ) 8
Catalytic Nucleophile/Basecarbonyl oxygen of C-2 acetamido group of substrate
Catalytic Proton DonorAsp
NoteMechanism shown in Macauley et al. (2005) JBC 280:25313-25322
External resourcesCAZypedia;
Commercial Enzyme Provider(s)PROZOMIX;
Statistics GenBank accession (866); Uniprot accession (107); PDB accession (64); 3D entries (6); cryst (0)
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 CFA72_03315   Streptococcus pyogenes GURSA1 ASO68058.1    
 SPYH293_01193 (HyL)   Streptococcus pyogenes H293 CDJ55441.1    
 CRD75_06595   Streptococcus pyogenes HarveyGAS ATL57227.1    
 HKU360_01353   Streptococcus pyogenes HKU360 AIW25156.1    
 HKU488_01252   Streptococcus pyogenes HKU488 AKP82181.1    
 L897_06535   Streptococcus pyogenes HSC5 AGQ27953.1    
 JMUB1235_1224   Streptococcus pyogenes JMUB1235 BAV55478.1    
 SPYJRS4_1260 (HyL)   Streptococcus pyogenes JRS4 BAR44760.1
AKI76495.1
   
 CCX85_06530   Streptococcus pyogenes JS12 AUG50774.1    
 SPYKS030_05750   Streptococcus pyogenes KS030 BBB87977.1    
 M1GAS476_1381 (HyL)   Streptococcus pyogenes M1 476 BAM30710.1    
 O-glycoprotein β-N-acetylglucosaminidase (SPy1600) 3.2.1.169 Streptococcus pyogenes M1 GAS AAK34378.1
NP_269657.1
Q99YP8  
 FE90_1013 (HyL)   Streptococcus pyogenes M23ND AIQ01776.1    
 ABO05_02690   Streptococcus pyogenes M28PF1 AKJ92195.1    
 M3B_0652 (HyL)   Streptococcus pyogenes M3-b BAU60022.1    
 AWM59_02730   Streptococcus pyogenes MEW123 AMA70173.1    
 AWM58_06365   Streptococcus pyogenes MEW427 AMA69267.1    
 MGAS10270_Spy1430 (hyl)   Streptococcus pyogenes MGAS10270 ABF34495.1 Q1JFR4  
 M6_Spy1332   Streptococcus pyogenes MGAS10394 AAT87467.1    
 MGAS10750_Spy1423 (hyl)   Streptococcus pyogenes MGAS10750 ABF38373.1 Q1J5L3  
 MGAS11027_1269   Streptococcus pyogenes MGAS11027 ANC24259.1    
 MGAS15252_1199   Streptococcus pyogenes MGAS15252 AFC66535.1    
 MGAS1882_1260   Streptococcus pyogenes MGAS1882 AFC68465.1    
 MGAS2096_Spy1335 + MGAS2096_Spy1334 (hyl) (fragment)   Streptococcus pyogenes MGAS2096 ABF36386.1
ABF36387.1
   
 MGAS23530_1178   Streptococcus pyogenes MGAS23530 ANC25854.1    
 MGAS27061_1214   Streptococcus pyogenes MGAS27061 ANC27483.1    
 Hyl   Streptococcus pyogenes MGAS315 AAM79901.1
NP_665098.1
Q8K6L2  
 M5005_Spy_1314 (HyL)   Streptococcus pyogenes MGAS5005 AAZ51932.1    
 M28_Spy1355 (HyL)   Streptococcus pyogenes MGAS6180 AAX72465.1    
 Hyl   Streptococcus pyogenes MGAS8232 AAL98163.1
NP_607664.1
Q8P022  
 MGAS9429_Spy1308 (hyl)   Streptococcus pyogenes MGAS9429 ABF32495.1 Q1JKS4  
 MTB313_1331 (HyL)   Streptococcus pyogenes MTB313 BAQ51738.1    
 MTB314_1250 (HyL)   Streptococcus pyogenes MTB314 BAQ53413.1    
 NCTC10085_01230 (HyL)   Streptococcus pyogenes NCTC10085 SQG54861.1    
 NCTC10874_01248 (HyL)   Streptococcus pyogenes NCTC10874 SQG15768.1    
 NCTC10876_00559 (HyL)   Streptococcus pyogenes NCTC10876 SQF62372.1    
 NCTC10877_00552 (HyL)   Streptococcus pyogenes NCTC10877 SQH10160.1    
 NCTC10879_00553 (HyL)   Streptococcus pyogenes NCTC10879 SQG27868.1    
 NCTC10880_01265 (HyL)   Streptococcus pyogenes NCTC10880 SQG40772.1    
 NCTC12044_01180 (HyL)   Streptococcus pyogenes NCTC12044 SQH27024.1    
 NCTC12045_01053 (HyL)   Streptococcus pyogenes NCTC12045 SQE97931.1    
 NCTC12046_01319 (HyL)   Streptococcus pyogenes NCTC12046 SQF19988.1    
 NCTC12047_01243 (HyL)   Streptococcus pyogenes NCTC12047 SQF21705.1    
 NCTC12048_00640 (HyL)   Streptococcus pyogenes NCTC12048 SQF14014.1    
 NCTC12050_00537 (HyL)   Streptococcus pyogenes NCTC12050 SQF15588.1    
 NCTC12052_01370 (HyL)   Streptococcus pyogenes NCTC12052 SQF52573.1    
 NCTC12057_01323 (HyL)   Streptococcus pyogenes NCTC12057 SQF10673.1    
 NCTC12058_01257 (HyL)   Streptococcus pyogenes NCTC12058 SQF07697.1    
 NCTC12059_00553 (HyL)   Streptococcus pyogenes NCTC12059 SQE77896.1    
 NCTC12062_00561 (HyL)   Streptococcus pyogenes NCTC12062 SQF26814.1    
 NCTC12064_00597 (HyL)   Streptococcus pyogenes NCTC12064 SQF22766.1    
 NCTC12066_00538 (HyL)   Streptococcus pyogenes NCTC12066 SQE92508.1    
 NCTC12067_01191 (HyL)   Streptococcus pyogenes NCTC12067 SQF56034.1    
 NCTC12068_01225 (HyL)   Streptococcus pyogenes NCTC12068 SQF60626.1    
 NCTC12069_01255 (HyL)   Streptococcus pyogenes NCTC12069 SQF04030.1    
 NCTC12696_01239 (HyL)   Streptococcus pyogenes NCTC12696 SQF12834.1    
 NCTC12840_00262 (HyL)   Streptococcus pyogenes NCTC12840 SQF35538.1    
 NCTC13736_00551 (HyL)   Streptococcus pyogenes NCTC13736 SQG94587.1    
 NCTC13737_00555 (HyL)   Streptococcus pyogenes NCTC13737 SQH22111.1    
 NCTC13738_01312 (HyL)   Streptococcus pyogenes NCTC13738 SQG20704.1    
 NCTC13739_00555 (HyL)   Streptococcus pyogenes NCTC13739 SQH08503.1    
 NCTC13742_01413 (HyL)   Streptococcus pyogenes NCTC13742 SQG24920.1    
 NCTC13743_00578 (HyL)   Streptococcus pyogenes NCTC13743 SQG22362.1    
 NCTC13744_01246 (HyL)   Streptococcus pyogenes NCTC13744 SQG73453.1    
 NCTC13745_01364 (HyL)   Streptococcus pyogenes NCTC13745 SQH48421.1    
 NCTC13751_01459 (HyL)   Streptococcus pyogenes NCTC13751 SQH63054.1    
 NCTC4001_00356 (HyL)   Streptococcus pyogenes NCTC4001 SQF49924.1    
 NCTC5163_01431 (HyL)   Streptococcus pyogenes NCTC5163 SQE57488.1    
 NCTC5164_01431 (HyL)   Streptococcus pyogenes NCTC5164 SQE90981.1    
 NCTC8195_01420 (HyL)   Streptococcus pyogenes NCTC8195 SQF46229.1    
 ERS445054_01436 (HyL)   Streptococcus pyogenes NCTC8198 CKH04861.1    
 NCTC8224_00594 (HyL)   Streptococcus pyogenes NCTC8224 SRX90574.1    
 NCTC8225_00674 (HyL)   Streptococcus pyogenes NCTC8225 SQE38269.1    
 NCTC8227_01275 (HyL)   Streptococcus pyogenes NCTC8227 SQG52913.1    
 NCTC8230_01426 (HyL)   Streptococcus pyogenes NCTC8230 SQF61204.1    
 NCTC8231_00557 (HyL)   Streptococcus pyogenes NCTC8231 SQF32366.1    
 NCTC8300_00560 (HyL)   Streptococcus pyogenes NCTC8300 SQF01671.1    
 NCTC8304_01255 (HyL)   Streptococcus pyogenes NCTC8304 SQG97113.1    
 NCTC8314_00611 (HyL)   Streptococcus pyogenes NCTC8314 SQE92538.1    
 NCTC8316_01261 (HyL)   Streptococcus pyogenes NCTC8316 SRX89588.1    
 NCTC8320_01382 (HyL)   Streptococcus pyogenes NCTC8320 SQG44044.1    
 NCTC8322_01345 (HyL)   Streptococcus pyogenes NCTC8322 SRX87897.1    
 NCTC8324_00684 (HyL)   Streptococcus pyogenes NCTC8324 SQF38270.1    
 NCTC8326_00551 (HyL)   Streptococcus pyogenes NCTC8326 SQF57039.1    
 NCTC8328_00651 (HyL)   Streptococcus pyogenes NCTC8328 SQF09378.1    
 NCTC8332_01431 (HyL)   Streptococcus pyogenes NCTC8332 SQF18205.1    
 NCTC8370_00552 (HyL)   Streptococcus pyogenes NCTC8370 SQH67856.1    
 SD89_02740   Streptococcus pyogenes NGAS322 AKZ50040.1    
 DK93_02705   Streptococcus pyogenes NGAS327 AKI38372.1    
 DK92_02820   Streptococcus pyogenes NGAS596 AKI36763.1    
 SD90_06060   Streptococcus pyogenes NGAS638 AKZ52495.1    
 DI45_07475   Streptococcus pyogenes NGAS743 AKI35833.1    
 C5P47_06400   Streptococcus pyogenes NGAS979 AWS23573.1    
 A4265_05840   Streptococcus pyogenes NS53 ANC74791.1    
 Spy49_1236c (HyL)   Streptococcus pyogenes NZ131 ACI61522.1 B5XMG0  
 SPs0567   Streptococcus pyogenes SSI-1 BAC63662.1
NP_801829.1
F7IV97  
 VT08_06480   Streptococcus pyogenes STAB09014 ANP29859.1    
 B4W66_06545   Streptococcus pyogenes STAB090229 ASQ21555.1    
 VU19_06965   Streptococcus pyogenes STAB10015 AKL63572.1    
 STAB1102_06475   Streptococcus pyogenes STAB1102 AIG49217.1    
Top


Last update: 2018-07-09 © Copyright 1998-2018
AFMB - CNRS - Université d'Aix-Marseille