Glycoside Hydrolase Family 84

Activities in FamilyN-acetyl β-glucosaminidase (EC 3.2.1.52); hyaluronidase (EC 3.2.1.35); [protein]-3-O-(GlcNAc)-L-Ser/Thr β-N-acetylglucosaminidase (EC 3.2.1.169)
Mechanism Retaining
3D Structure Status( β / α ) 8
Catalytic Nucleophile/Basecarbonyl oxygen of C-2 acetamido group of substrate
Catalytic Proton DonorAsp
NoteMechanism shown in Macauley et al. (2005) JBC 280:25313-25322
External resourcesCAZypedia;
Commercial Enzyme Provider(s)PROZOMIX;
Statistics GenBank accession (866); Uniprot accession (107); PDB accession (64); 3D entries (6); cryst (0)
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 B7C51_22400   Paenibacillus larvae subsp. pulvifaciens SAG 10367 ARF70007.1    
 ABE82_01765   Paenibacillus peoriae HS311 ALA40350.1    
 VK72_01750   Paenibacillus polymyxa ATCC 15970 APQ57575.1    
 LK13_14680   Paenibacillus polymyxa CF05 AIY09750.1    
 X809_01520   Paenibacillus polymyxa CR1 AHC18033.1    
 PPE_00341   Paenibacillus polymyxa E681 ADM68223.1 E0RC48  
 C1A50_0350   Paenibacillus polymyxa HY96-2 AUS24589.1    
 AOU00_14400   Paenibacillus polymyxa J AOK90919.1    
 PPM_0365 (HyL)   Paenibacillus polymyxa M1 CCC83302.1    
 RE92_10015   Paenibacillus polymyxa Sb3-1 AJE51346.1    
 PPSC2_c0392   Paenibacillus polymyxa SC2 ADO54376.1 E3ECT2  
 PPSQR21_003430   Paenibacillus polymyxa SQR-21 SQR21 AHM64054.1    
 PPYC1_22520   Paenibacillus polymyxa YC0136 APB72963.1    
 PPYC2_24865   Paenibacillus polymyxa YC0573 APB77956.1    
 DCC85_17430   Paenibacillus sp. CAA11 AWB45792.1    
 H70737_09440   Paenibacillus sp. FSL H7-0737 AIQ23051.1    
 P40081_31050   Paenibacillus sp. FSL P4-0081 AIQ32071.1    
 R50345_09880   Paenibacillus sp. FSL R5-0345 AIQ34888.1    
 R50912_27795   Paenibacillus sp. FSL R5-0912 AIQ43399.1    
 R70723_26645   Paenibacillus sp. FSL R7-0273 AIQ49084.1    
 ASL14_10115   Paenibacillus sp. IHB B 3084 ALP36460.1    
 C0638_06015   Paenibacillus sp. lzh-N1 AUO06120.1    
 HPL003_09490   Paenibacillus terrae HPL-003 AET58659.1    
 BDI_1142   Parabacteroides distasonis ATCC 8503 ABR42905.1 A6LB41  
 CI960_09425   Parabacteroides sp. CT06 AST53562.1    
 A4V02_09055   Parabacteroides sp. YL27 ANU63860.1    
 Plav_1649   Parvibaculum lavamentivorans DS-1 ABS63268.1 A7HTN5  
 AQ505_01415   Pedobacter sp. PACM 27299 ALL04266.1    
 Pmob_0472   Petrotoga mobilis SJ95 ABX31208.1 A9BFN8  
 HYN04_08800   Phenylobacterium sp. HYN0004 AWM77853.1    
 PHZ_c1061 (fragment)   Phenylobacterium zucineum HLK1 ACG77475.1 B4R7U2  
 SMSP2_00909   Phycisphaerae bacterium SM-Chi-D1 AQQ70557.1    
 HMPREF9137_0590   Prevotella denticola F0289 AEA21503.1    
 ADJ77_06260   Prevotella fusca JCM 17724 AKU69696.1    
 CRM71_08685   Prevotella jejuni CD3_33 AUI55353.1    
 HMPREF0659_A5046   Prevotella melaninogenica ATCC 25845 ADK95569.1 D9RR08  
 CEP85_00415   Prevotella melaninogenica FDAARGOS_306 ASE16680.1    
 PMEL1_00044   Prevotella melaninogenica GAI 07411 BBA28154.1    
 AXF22_01355   Prevotella scopos JCM 17725 ANR72191.1    
 BCB70_12070 (fragment)   Propionibacterium sp. oral taxon 193 F0672 AOH46838.1    
 AFB00_25670 (fragment)   Pseudonocardia sp. HH130630-07 ANY09084.1    
 hyaluronidase   Rickettsia felis ADD74153.1 D4N370  
 RF_p56   Rickettsia felis URRWXCal2 AAY62307.1
AAY62351.1
Q4UJA6  
 SACE_0529   Saccharopolyspora erythraea NRRL 2338 CAL99875.1 A4F751  
 SACE_7066   Saccharopolyspora erythraea NRRL 2338 CAM06227.1 A4FQA2  
 SELR_08510   Selenomonas ruminantium subsp. lactilytica TAM6421 BAL82559.1    
 Selsp_1425   Selenomonas sputigena ATCC 35185 AEC00383.1    
 CGQ25_17110   Sinomonas sp. R1AF57 ASN53590.1    
 KO02_20065   Sphingobacterium sp. ML3W AIM38739.1    
 BN1088_1430317   Sphingobacterium sp. PM2-P1-29 CDS91913.1    
 BN1088_1432989   Sphingobacterium sp. PM2-P1-29 CDT03377.1    
 TS85_03725   Sphingomonas hengshuiensis WHSC-8 AJP71124.1    
 BJP26_08285   Sphingomonas melonis TY AOW23572.1    
 CP552_02250   Sphingomonas melonis ZJ26 ATI54565.1    
 AV944_14970   Sphingomonas sp. LK11 APX66913.1    
 A7E77_14930   Sphingomonas sp. NIC1 ANC88070.1    
 MC45_11905   Sphingomonas taxi ATCC 55669 AIT06969.1    
 SmB9_36690   Sphingosinicella microcystinivorans B9 BBE36011.1    
 IMCC21906_02147   Spongiibacter sp. IMCC21906 AKH69814.1    
 Snas_2451   Stackebrandtia nassauensis DSM 44728 ADD42134.1 D3Q4V4  
 SZO_04490   Steptococcus equi subsp. zooepidemicus H70 CAW98371.1    
 SDSE167_1709 (HyL)   Streptococcus dysgalactiae subsp. equisimilis 167 BAN94096.1    
 SDSE_1739 (HyL)   Streptococcus dysgalactiae subsp. equisimilis AC-2713 CCI63232.1    
 SDE12394_08290   Streptococcus dysgalactiae subsp. equisimilis ATCC 12394 ADX25098.1    
 SDEG_1588 (HyL)   Streptococcus dysgalactiae subsp. equisimilis GGS_124 BAH82082.1 C5WI67  
 NCTC5370_01558 (HyL)   Streptococcus dysgalactiae subsp. equisimilis NCTC5370 SQE86337.1    
 NCTC5371_01646 (HyL)   Streptococcus dysgalactiae subsp. equisimilis NCTC5371 SQF78783.1    
 NCTC6179_01661 (HyL)   Streptococcus dysgalactiae subsp. equisimilis NCTC6179 SQF67469.1    
 NCTC7136_00951 (HyL)   Streptococcus dysgalactiae subsp. equisimilis NCTC7136 SQG92759.1    
 NCTC9414_00719 (HyL)   Streptococcus dysgalactiae subsp. equisimilis NCTC9414 SQF68702.1    
 GGS_1455 (HyL)   Streptococcus dysgalactiae subsp. equisimilis RE378 BAM61590.1    
 SEQ_1693   Streptococcus equi subsp. equi 4047 CAW94746.1 C0MC42  
 SE071780_01724   Streptococcus equi subsp. equi ATCC 39506 ASB97311.1    
 SeseC_02032 (HyA)   Streptococcus equi subsp. zooepidemicus ATCC 35246 AEJ25853.1    
 β-N-acetylglucosaminidase (HylZ)   Streptococcus equi subsp. zooepidemicus ATCC 39920 AHJ09604.1    
 Q426_01285   Streptococcus equi subsp. zooepidemicus CY AIA67201.1    
 Sez_1507   Streptococcus equi subsp. zooepidemicus MGCS10565 ACG62840.1 B4U4C3  
 NCTC11606_01500 (NagJ)   Streptococcus equi subsp. zooepidemicus NCTC11606 SQF54506.1    
 NCTC11824_01516 (NagJ)   Streptococcus equi subsp. zooepidemicus NCTC11824 SQG17698.1    
 NCTC12090_01599 (NagJ)   Streptococcus equi subsp. zooepidemicus NCTC12090 SQF06103.1    
 NCTC6176_01545 (NagJ)   Streptococcus equi subsp. zooepidemicus NCTC6176 SQF82162.1    
 NCTC7022_01661 (NagJ)   Streptococcus equi subsp. zooepidemicus NCTC7022 SQE96523.1    
 smi_1537   Streptococcus mitis B6 CBJ22777.1 D3HA79  
 AXK38_07515   Streptococcus mitis SVGS_061 AMH89096.1    
 CO686_07620   Streptococcus oralis FDAARGOS_367 ATF57309.1    
 BWR56_0605   Streptococcus oralis S.MIT/ORALIS-351 AQA08903.1    
 BWR56_0313   Streptococcus oralis S.MIT/ORALIS-351 AQA08844.1    
 SOR_1642   Streptococcus oralis Uo5 CBZ01293.1    
 STP_1214+STP_1213   Streptococcus parauberis KCTC 11537 AEF25661.1
AEF25662.1
   
 STAB904_07030   Streptococcus pyogenes 1E1 AIW12140.1    
 SP5448_03015   Streptococcus pyogenes 5448 AKK70039.1    
 STAB1101_05800   Streptococcus pyogenes 7F7 AIT77818.1    
 A20_1348c (HyL)   Streptococcus pyogenes A20 AFV38428.1    
 SPYALAB49_001292   Streptococcus pyogenes Alab49 AEQ24885.1    
 SPAP1_02925   Streptococcus pyogenes AP1 AKG27575.1    
 AUQ45_1301 (HyL)   Streptococcus pyogenes AP53 AMY97855.1    
 DP15_382   Streptococcus pyogenes ATCC 19615 AIL11961.1    
 SpyM6D471_06010   Streptococcus pyogenes D471 AKI78166.1    
 AL510_06480   Streptococcus pyogenes FDAARGOS_149 AMH03489.1    
 B2G65_03315   Streptococcus pyogenes GUR ASO73774.1    
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