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Glycoside Hydrolase Family 5

Activities in Family[retaining] arabinoxylan-specific endo-β-1,4-xylanase (EC 3.2.1.-);
β-1,3-mannanase (EC 3.2.1.-);
β-rutinosidase /α-L-rhamnose-(1,6)-β-D-glucosidase (EC 3.2.1.-);
Glucomannan-specific endo-β-1,4-glucanase (EC 3.2.1.-);
Mannan exo-β-1,4-mannosidase (EC 3.2.1.-);
Steryl β-glucosidase (EC 3.2.1.104);
Endoglycosylceramidase (EC 3.2.1.123);
Chitosanase (EC 3.2.1.132);
β-D-galactofuranosidase (EC 3.2.1.146);
β-primeverosidase (EC 3.2.1.149);
Oligoxyloglucan reducing-end-specific cellobiohydrolase (EC 3.2.1.150);
Xyloglucan-specific endo-β-1,4-glucanase / endo-xyloglucanase (EC 3.2.1.151);
Endo-β-1,6-galactanase (EC 3.2.1.164);
Hesperidin 6-O-α-L-rhamnosyl-β-glucosidase (EC 3.2.1.168);
β-glucosidase (EC 3.2.1.21);
β-galactosidase (EC 3.2.1.23);
β-mannosidase (EC 3.2.1.25);
Xylan β-1,4-xylosidase (EC 3.2.1.37);
Endo-β-1,3-glucanase / laminarinase (EC 3.2.1.39);
Endo-β-1,4-glucanase (EC 3.2.1.4);
β-glucosylceramidase (EC 3.2.1.45);
β-galactosylceramidase (EC 3.2.1.46);
β-N-acetylhexosaminidase (EC 3.2.1.52);
α-L-arabinofuranosidase (EC 3.2.1.55);
Exo-β-1,3-glucanase (EC 3.2.1.58);
Endo-β-1,3(4)-glucanase / lichenase-laminarinase (EC 3.2.1.6);
Lichenase / endo-β-1,3-1,4-glucanase (EC 3.2.1.73);
Exo-β-1,4-glucanase / cellodextrinase (EC 3.2.1.74);
Endo-β-1,6-glucanase (EC 3.2.1.75);
Endo-β-1,4-mannanase (EC 3.2.1.78);
Endo-β-1,4-xylanase (EC 3.2.1.8);
Cellobiohydrolase (EC 3.2.1.91);
Mechanism Retaining e
ClanGH-A
3D Structure Status( β / α ) 8 barrel
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental)
NoteOnce known as cellulase family A; many members have been assigned to subfamilies as described by Aspeborg et al. (2012) BMC Evol Biol. 12(1):186 (PMID: 22992189).
External resourcesCAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; NZYTech; PROZOMIX;
Statistics GenBank accession (31227); Uniprot accession (673); PDB accession (296); 3D entries (110); cryst (0)
Summary
Download GH5 (44486) Taxonomic display Structure (110) Characterized (624)
| 1 | ... | 16 | 17 | 18 | 19 | 20 | 21 | 22 | 23 | 24 | ... | 245 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D Subf
 EJJ34_09925   Bacillus subtilis subsp. subtilis NCIB 3610 = ATCC 6051 = DSM 10 QCX89517.1     2
 BEP06_07030   Bacillus subtilis subsp. subtilis PG10 ANY35199.1     2
 D9C11_22230   Bacillus subtilis subsp. subtilis PJ-7 AYK67880.1     2
 BEP07_07080   Bacillus subtilis subsp. subtilis PS38 ANY37961.1     2
 BHY07_09960   Bacillus subtilis subsp. subtilis QB5412 AOT48097.1     2
 S100333_02083   Bacillus subtilis subsp. subtilis SRCM100333 ASB69976.1     2
 S100757_02006   Bacillus subtilis subsp. subtilis SRCM100757 ARW02937.1     2
 S100761_02016   Bacillus subtilis subsp. subtilis SRCM100761 ASB57345.1     2
 S101392_02048   Bacillus subtilis subsp. subtilis SRCM101392 ASB93521.1     2
 S101444_02015   Bacillus subtilis subsp. subtilis SRCM101444 ARV98863.1     2
 D9C14_18840   Bacillus subtilis subsp. subtilis SSJ-1 AYK63269.1     2
 HIR76_17630 (EglS)   Bacillus subtilis subsp. subtilis str. 168 QJF44448.1     2
 HIR78_09845 (EglS)   Bacillus subtilis subsp. subtilis str. 168 QJP88315.1     2
 endo-β-1,4-glucanase (EglS;BglC;Gld;BSU18130;BsCel5;BsCel5A) (Cel5A) 3.2.1.4 Bacillus subtilis subsp. subtilis str. 168 CAA82317.1
AEJ76923.1
AIY93123.1
AQR81804.1
AQR86018.1
CAA97610.1
CAB13696.2
NP_389695.1
NP_389695.2		 A0A6M3ZBL5
G1DE47
P10475		 3PZT[A,B]
3PZU[A,B]
3PZV[A,B,C,D] 		2
 BSUB_01951 (EglS)   Bacillus subtilis subsp. subtilis str. AG1839 AIC44469.1     2
 I653_09410   Bacillus subtilis subsp. subtilis str. BAB-1 AGI29134.1     2
 A7A1_0701   Bacillus subtilis subsp. subtilis str. BSP1 AGA21319.1     2
 BSUA_01951 (EglS)   Bacillus subtilis subsp. subtilis str. JH642 substr. AG174 AIC40237.1     2
 Q433_10715   Bacillus subtilis subsp. subtilis str. OH 131.1 AIC98399.1     2
 I33_2031   Bacillus subtilis subsp. subtilis str. RO-NN-1 AEP90990.1     2
 HC658_19150 (EglS)   Bacillus subtilis subsp. subtilis UCMB5021 QJD04277.1     2
 HC659_19120 (EglS)   Bacillus subtilis subsp. subtilis UCMB5121 QJD00294.1     2
 endo-β-1,4-glucanase 3.2.1.4 Bacillus subtilis subsp. subtilis UMC7 AGG11030.1 M1R5G7   2
 BSSX_2016   Bacillus subtilis SX01705 ASK23911.1     2
 endo-β-1,4-glucanase (fragment)   Bacillus subtilis SYYS AFV95351.1     2
 A3772_09840   Bacillus subtilis SZMC 6179J AMS47376.1     2
 β-1,4-endo-glucanase, partial (fragment)   Bacillus subtilis T28d AHD24514.1     2
 BIS30_19935   Bacillus subtilis T30 AJW87252.1     2
 β-1,4-endo-glucanase, partial (fragment)   Bacillus subtilis t37a AHD24506.1     2
 ORF (fragment)   Bacillus subtilis T41a AIT71752.1     2
 cellulase   Bacillus subtilis TB-2 ABS70711.1     2
 CLD04_10445   Bacillus subtilis TLO3 ASZ61563.1     2
 M036_09535   Bacillus subtilis TO-A AII35811.1     2
 ABU16_2893   Bacillus subtilis TO-A JPC AKN13969.1     2
 ABA10_09875   Bacillus subtilis UD1022 AKI92270.1     2
 endo-1,4-β-glucanase   Bacillus subtilis VSDB5 QEA08555.1     2
 BKN48_19800   Bacillus subtilis VV2 AOY07432.1     2
 β-1,4-endo-glucanase, partial (fragment)   Bacillus subtilis w AHD24516.1     2
 D3Z87_09910   Bacillus subtilis WB800N AYE64410.1     2
 cellulase (Egls3)   Bacillus subtilis WL001 AOY41715.1     2
 endoglucanase (CelW)   Bacillus subtilis WL001 AHZ62779.1     2
 C663_1868 (EglS)   Bacillus subtilis XF-1 AGE63656.1     2
 xylanase (Xyl141)   Bacillus subtilis Xyl14-KBRB ADP09027.1     2
 β-1,4-endo-glucanase, partial (fragment)   Bacillus subtilis Y AHD24507.1     2
 GFX43_011830 (EglS)   Bacillus subtilis ZD01 QGU24489.1     2
 G4P54_10325   Bacillus tequilensis EA-CB0015 QIW80171.1     2
 endoglucanase (CeL)   Bacillus tequilensis S17I28 AIJ27554.1     2
 OAT02_12145   Bacillus thuringiensis 4F5 UYC99719.1     48
 K8Z20_16180   Bacillus thuringiensis ABTS-1857 UEL15390.1     48
 K8Z42_07320   Bacillus thuringiensis ABTS-351 UEK86583.1     48
 CAB88_17695   Bacillus thuringiensis ATCC 10792 ARP61015.1     48
 JRY14_00560   Bacillus thuringiensis B13 UJP57658.1     48
 K8Z39_13590   Bacillus thuringiensis B401 UEK81056.1     48
 BtBc_18320   Bacillus thuringiensis Bc601 AMX80339.1     48
 PJW01_14750   Bacillus thuringiensis BLB1 WCH14669.1     48
 BMB171_C3198   Bacillus thuringiensis BMB171 ADH08008.1     48
 K8Z33_00160   Bacillus thuringiensis BMP144 UEL06653.1     48
 M3Y14_29340   Bacillus thuringiensis Bt Gxmzu777-1 UYX52449.1     48
 FBF59_02475   Bacillus thuringiensis BT-59 QCJ53820.1     48
 FM050_21605   Bacillus thuringiensis Bt-GS57 QTM18274.1     48
 BTI247_37720   Bacillus thuringiensis Bt18247 AOM12154.1     48
 AXW78_16645   Bacillus thuringiensis Bt185 AMR05601.1     48
 BTB_c35880   Bacillus thuringiensis Bt407 AFV19270.1     48
 EWV32_21185   Bacillus thuringiensis Bti QBM63051.1     48
 BtSCAC15_19180   Bacillus thuringiensis C15 AZR78328.1     48
 QOM09_17755   Bacillus thuringiensis DHC4 WIG10776.1     48
 FOC90_05560   Bacillus thuringiensis FDAARGOS_796 QKH22128.1     48
 β-glucosidase   Bacillus thuringiensis G13 ALJ10949.1     48
 K8Z38_16560   Bacillus thuringiensis GC-91 UEL08381.1     48
 KPG64_18520   Bacillus thuringiensis GR007 QWS48247.1     48
 G9298_30465   Bacillus thuringiensis H3 QPW51950.1     48
 BTG_01865   Bacillus thuringiensis HD-771 AFQ13876.1     48
 BTF1_15010   Bacillus thuringiensis HD-789 AFQ27177.1     48
 AS86_507   Bacillus thuringiensis HD1002 AJH08483.1     48
 A3L20_18535   Bacillus thuringiensis HD12 AMR88058.1     48
 HBA75_28885   Bacillus thuringiensis HER1410 QKO36645.1     48
 FHE73_17895   Bacillus thuringiensis HM-311 QCY62510.1     48
 AC241_17265   Bacillus thuringiensis HS18-1 AKR12420.1     48
 endo-β-1,4-glucanase (fragment)   Bacillus thuringiensis IARI-SP-6 AGW99983.1     2
 J2N67_005086   Bacillus thuringiensis IMBL-B9 USP54837.1     48
 F9800_23415   Bacillus thuringiensis JW-1 QFP89888.1     48
 LIT28_16640   Bacillus thuringiensis KF1 USL11633.1     48
 BCM43_11585   Bacillus thuringiensis KNU-07 ANV74005.1     48
 B4918_19610   Bacillus thuringiensis L-7601 AQY42210.1     48
 Q9G86_17415   Bacillus thuringiensis L1 WLP62420.1     48
 PJW02_12735   Bacillus thuringiensis Lip WCH13370.1     48
 CUC43_32110   Bacillus thuringiensis LM1212 AXY11283.1     28
 MC28_G027   Bacillus thuringiensis MC28 AFU17760.1     48
 BT246_38300 (fragment)   Bacillus thuringiensis MYBT18246 ANS49178.1     48
 BT246_63680 (fragment)   Bacillus thuringiensis MYBT18246 ANS51660.1     48
 BT246_66980 (fragment)   Bacillus thuringiensis MYBT18246 ANS51990.1     48
 K8Z23_08760   Bacillus thuringiensis NB-176 UEK99738.1     48
 D7J84_21585   Bacillus thuringiensis QZL38 AYF84711.1     48
 K8Z41_07315   Bacillus thuringiensis SA11 UEK93171.1     48
 Bt4C1_17180   Bacillus thuringiensis serovar alesti BGSC 4C1 AND10926.1     48
 CT43_CH3456   Bacillus thuringiensis serovar chinensis CT-43 AEA17123.1     48
 A9498_18185   Bacillus thuringiensis serovar coreanensis ST7 ANN35388.1     48
 BT4G5_29985 (fragment)   Bacillus thuringiensis serovar galleriae HD-29 AJA23074.1     48
 BT4G5_18355   Bacillus thuringiensis serovar galleriae HD-29 AJA22935.1     48
 NF53_3388   Bacillus thuringiensis serovar indiana HD521 AKR36466.1     48
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