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Glycoside Hydrolase Family 5

Activities in Family[retaining] arabinoxylan-specific endo-β-1,4-xylanase (EC 3.2.1.-);
β-1,3-mannanase (EC 3.2.1.-);
β-rutinosidase /α-L-rhamnose-(1,6)-β-D-glucosidase (EC 3.2.1.-);
Glucomannan-specific endo-β-1,4-glucanase (EC 3.2.1.-);
Mannan exo-β-1,4-mannosidase (EC 3.2.1.-);
Steryl β-glucosidase (EC 3.2.1.104);
Endoglycosylceramidase (EC 3.2.1.123);
Chitosanase (EC 3.2.1.132);
β-D-galactofuranosidase (EC 3.2.1.146);
β-primeverosidase (EC 3.2.1.149);
Oligoxyloglucan reducing-end-specific cellobiohydrolase (EC 3.2.1.150);
Xyloglucan-specific endo-β-1,4-glucanase / endo-xyloglucanase (EC 3.2.1.151);
Endo-β-1,6-galactanase (EC 3.2.1.164);
Hesperidin 6-O-α-L-rhamnosyl-β-glucosidase (EC 3.2.1.168);
β-glucosidase (EC 3.2.1.21);
β-galactosidase (EC 3.2.1.23);
β-mannosidase (EC 3.2.1.25);
Xylan β-1,4-xylosidase (EC 3.2.1.37);
Endo-β-1,3-glucanase / laminarinase (EC 3.2.1.39);
Endo-β-1,4-glucanase (EC 3.2.1.4);
β-glucosylceramidase (EC 3.2.1.45);
β-galactosylceramidase (EC 3.2.1.46);
β-N-acetylhexosaminidase (EC 3.2.1.52);
α-L-arabinofuranosidase (EC 3.2.1.55);
Exo-β-1,3-glucanase (EC 3.2.1.58);
Endo-β-1,3(4)-glucanase / lichenase-laminarinase (EC 3.2.1.6);
Lichenase / endo-β-1,3-1,4-glucanase (EC 3.2.1.73);
Exo-β-1,4-glucanase / cellodextrinase (EC 3.2.1.74);
Endo-β-1,6-glucanase (EC 3.2.1.75);
Endo-β-1,4-mannanase (EC 3.2.1.78);
Endo-β-1,4-xylanase (EC 3.2.1.8);
Cellobiohydrolase (EC 3.2.1.91);
Mechanism Retaining e
ClanGH-A
3D Structure Status( β / α ) 8 barrel
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental)
NoteOnce known as cellulase family A; many members have been assigned to subfamilies as described by Aspeborg et al. (2012) BMC Evol Biol. 12(1):186 (PMID: 22992189).
External resourcesCAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; NZYTech; PROZOMIX;
Statistics GenBank accession (31227); Uniprot accession (673); PDB accession (296); 3D entries (110); cryst (0)
Summary
Download GH5 (44486) Taxonomic display Structure (110) Characterized (624)
| 1 | ... | 14 | 15 | 16 | 17 | 18 | 19 | 20 | 21 | 22 | ... | 245 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D Subf
 SD85_09595   Bacillus spizizenii NRS 231 AJD36478.1     2
 BSUW23_09325 (EglS)   Bacillus spizizenii str. W23 ADM37911.1     2
 DQ231_09570   Bacillus spizizenii SW83 AXC53088.1     2
 GYO_2183   Bacillus spizizenii TU-B-10 AEP86815.1     2
 QI003_13235   Bacillus stercoris BS21 WGV93519.1     2
 QI003_09810   Bacillus stercoris BS21 WGV97294.1     2
 BSB_06040 (EglS)   Bacillus stercoris BST19 BEV37531.1     2
 QA442_12785 (EglS)   Bacillus stercoris Mal05 WGE37321.1     2
 R0126_15890   Bacillus stratosphericus AIMST-CREST02 WOQ72095.1     7
 endo-1,4-β-glucanase (fragment)   Bacillus subtilis AEK70950.1     2
 endo-1,4-β-glucanase (fragment)   Bacillus subtilis AEK70951.1     2
 endo-1,4-β-glucanase (fragment)   Bacillus subtilis AEK70952.1     2
 endo-β-1,4-glucanase 3.2.1.4 Bacillus subtilis AAA22307.1 Q45532   2
 BKP58_02035   Bacillus subtilis 29R7-12 API94754.1     2
 GII76_10330 (EglS)   Bacillus subtilis 73 QGH96744.1     2
 GII77_10435 (EglS)   Bacillus subtilis 75 QGI00875.1     2
 Bateq7PJ16_2005   Bacillus subtilis 7PJ-16 QHF57811.1     2
 beta 1,4 endo glucanase, partial (fragment)   Bacillus subtilis a10d AGV05392.1     2
 beta 1,4 endo glucanase, partial (fragment)   Bacillus subtilis a14h AGV05393.1    
 endocellulase   Bacillus subtilis A2 AFA26702.1     2
 β-1,3-1,4-glucanase / cellulase C (CelA;CelC) 3.2.1.4 Bacillus subtilis A8-8 AAO63626.1 Q6Y4Q1   2
 F0366_11415 (EglS)   Bacillus subtilis AMR1 QIR18797.1     2
 endoglucanase / cellulase (Cel-An5) (fragment)   Bacillus subtilis An5 AHX72143.1     2
 cellulase   Bacillus subtilis ASM6 AKQ62667.1     2
 HC662_19710 (EglS)   Bacillus subtilis At3 QJC88807.1     2
 KS07_08965   Bacillus subtilis ATCC 19217 AIW37597.1     2
 BS21228_00510   Bacillus subtilis ATCC 21228 AVL03010.1     2
 endo-1,4-β-glucanase (GlnC) (partial)   Bacillus subtilis ATTCAU195 AAN07019.1     2
 endo-β-1,4-glucanase, partial   Bacillus subtilis AuChE413 ALJ10582.1     2
 MA22_12095   Bacillus subtilis B-1 AIU77226.1     2
 β-1,4-endo-glucanase, partial (fragment)   Bacillus subtilis b5b AHD24502.1     2
 endo-β-1,4-glucanase (fragment)   Bacillus subtilis b5d AHC02484.1     2
 beta 1,4 endo glucanase, partial (fragment)   Bacillus subtilis b8a AGV05394.1     2
 endoglucanase (Egl173;Cel;EglS) 3.2.1.4 Bacillus subtilis BEC-1 / Y106 / shu-3 AAK39540.1
ADM12805.1
ADP05286.1		 Q93TJ6   2
 BEST7003_1842 (EglS)   Bacillus subtilis BEST7003 BAM58043.1     2
 C0W65_19480   Bacillus subtilis BJ3-2 AUS14012.1     2
 GTW28_10050 (EglS)   Bacillus subtilis BJQ0005 QHH20269.1     2
 endo-β-1,4-glucanase (Eg15) (Cel5A) 3.2.1.4 Bacillus subtilis BME-15 ACI15227.1
ACJ12786.1
ACJ12787.1
ACJ12788.1
ACJ12789.1
ACJ12790.1
ACJ12791.1
ACJ12792.1		 B6DVJ2
B6VEU9
B6VEV0
B6VEV1
B6VEV2
B6VEV3
B6VEV4
B6VEV5		   2
 endo-β-1,4-glucanase (Cel5H)   Bacillus subtilis BME12 ACM68436.1     2
 B7470_21865   Bacillus subtilis Bs-115 ARI88503.1     2
 β-glucanase   Bacillus subtilis BS-2 ABS70712.1
ABO37787.1		     2
 endo-β-1,4-glucanase (EG5C) 3.2.1.4 Bacillus subtilis BS-5 AVD69633.1
AVD69632.1		     2
 KO64_09220   Bacillus subtilis Bs-916 AIW30039.1     2
 endo-1,4-β-glucanohydrolase   Bacillus subtilis BS-DX4 AQT39609.1     2
 BS16045_01927   Bacillus subtilis BS16045 AOL97645.1     2
 β-1,4-endo glucanase, partial (fragment)   Bacillus subtilis BS3-2J AVV48623.1     2
 BSBS38_02055   Bacillus subtilis BS38 AOR98335.1     2
 BS49_20100 (EglS)   Bacillus subtilis BS49 CEI57006.1     2
 endo-β-1,4-glucanase (CMCase;BglC) 3.2.1.4 Bacillus subtilis BSE616 BAA00859.1 P23549   2
 BSn5_00410   Bacillus subtilis BSn5 ADV92718.1     2
 endo-β-1,4-glucanase   Bacillus subtilis BY-2 AGN52749.1     2
 endo-β-1,4-glucanase   Bacillus subtilis BY-4 AHA61366.1     2
 endo-β-1,4-glucanase (EglS;EG)   Bacillus subtilis C-36 ABG78039.1     2
 cellulase, partial (fragment)   Bacillus subtilis C05-16 AFH66774.1     2
 endo-β-1,4-glucanase (fragment)   Bacillus subtilis C11A ADP76527.1     2
 endo-β-1,4-glucanase (fragment)   Bacillus subtilis C11B1 ADP76526.1     2
 endo-β-1,4-glucanase (fragment)   Bacillus subtilis C8K1 ADP76528.1     2
 endo-β-1,4-glucanase (CelG) 3.2.1.4 Bacillus subtilis CHZ1 AAK94871.1 Q93LD0   2
 endo-β-1,4-glucanase (EglS) 3.2.1.4 Bacillus subtilis CK-2 CAA47429.1 G1DE47
P10475		   2
 BCV50_02950   Bacillus subtilis CW14 ARV44015.1     2
 endo-β-1,4-glucanase (Egl)   Bacillus subtilis dcy-1 ADH93702.1     2
 endo-β-1,4-glucanase, partial (fragment)   Bacillus subtilis DH4 QFS21919.1     2
 CJZ70_10320   Bacillus subtilis DKU_NT_02 ASU98698.1     2
 CJZ71_00325   Bacillus subtilis DKU_NT_03 ASV00768.1     2
 endo-β-1,4-glucanase (BglC;Gld) 3.2.1.4 Bacillus subtilis DLG AAA22496.1 P07983   2
 cellulase (CelDR) 3.2.1.4 Bacillus subtilis DR ABV45393.1
ACI63223.1		 A8D0T0
B6V3I2		   2
 endo-β-1,4-glucanase (fragment)   Bacillus subtilis DR-8806 AGT14428.1     2
 cellulase   Bacillus subtilis DR8806 AJS13457.1     2
 DTQ03_09345   Bacillus subtilis FB6-3 AXV61556.1     2
 FIU26_03810   Bacillus subtilis FDAARGOS_606 QDD03046.1     2
 endo-β-1,4-glucanase (ElgN)   Bacillus subtilis GhNa1397 QCW12957.1     2
 GSY53_17760 (EglS)   Bacillus subtilis GOT9 QHE17568.1     2
 BSK2_09725   Bacillus subtilis GQJK2 ARB37208.1     2
 β-1,4-endo-glucanase, partial (fragment)   Bacillus subtilis h13f AHD24515.1     2
 β-1,4-endo-glucanase, partial (fragment)   Bacillus subtilis h13h AHD24509.1     2
 β-1,4-endo-glucanase, partial (fragment)   Bacillus subtilis h14d AHD24508.1    
 β-1,4-endo-glucanase, partial (fragment)   Bacillus subtilis h14h AHD24511.1     2
 BSHJ0_02123   Bacillus subtilis HJ0-6 AOA54695.1     2
 AW03_018510 (BglC)   Bacillus subtilis HJ5 AKD35233.1     2
 D0819_05000   Bacillus subtilis HMNig-2 QFY84821.1     2
 cellulase   Bacillus subtilis Ho27 AIV00153.1     2
 A4A60_10410   Bacillus subtilis HRBS-10TDI13 AOS68054.1     2
 endo-β-1,4-glucanase (CelI15) 3.2.1.4 Bacillus subtilis I15 ACK38261.1 B7UAM4   2
 endo-β-1,4-glucanase 3.2.1.4 Bacillus subtilis IARI-SP-1 AGW99977.1 U3RAX4   2
 BHE96_09500   Bacillus subtilis J-5 APH35804.1     2
 endo-β-1,4-glucanase (Egl499;Egl330) 3.2.1.4 Bacillus subtilis JA18 AAZ22322.1 Q45T78   2
 HR084_09800 (EglS)   Bacillus subtilis JCL16 QKJ77900.1     2
 β-1,4-endo-glucanase, partial (fragment)   Bacillus subtilis k27k88 AHD24503.1    
 ORF (fragment)   Bacillus subtilis k36p88 AHZ90941.1    
 O7A_09975   Bacillus subtilis KCTC 1028 = ATCC 6051a AKC47378.1     2
 BSR08_06550   Bacillus subtilis KH2 API42192.1     2
 HT135_09975   Bacillus subtilis KKD1 QKS04605.1     2
 cellulase (Cel15;Cell15) 3.2.1.4 Bacillus subtilis LN ACR59602.1 C5I946   2
 cellulase (fragment)   Bacillus subtilis M3 QBX90330.1     2
 GII79_09735 (EglS)   Bacillus subtilis MB8_B1 QGI09060.1     2
 GII78_09790 (EglS)   Bacillus subtilis MB8_B10 QGI04865.1     2
 GII80_09700 (EglS)   Bacillus subtilis MB8_B7 QGI13265.1     2
 GII81_09735 (EglS)   Bacillus subtilis MB9_B1 QGI17605.1     2
 GII82_09800 (EglS)   Bacillus subtilis MB9_B4 QGI21840.1     2
 GII83_09735 (EglS)   Bacillus subtilis MB9_B6 QGI26879.1     2
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