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Glycoside Hydrolase Family 5

Activities in Family[retaining] arabinoxylan-specific endo-β-1,4-xylanase (EC 3.2.1.-);
β-1,3-mannanase (EC 3.2.1.-);
β-rutinosidase /α-L-rhamnose-(1,6)-β-D-glucosidase (EC 3.2.1.-);
Glucomannan-specific endo-β-1,4-glucanase (EC 3.2.1.-);
Mannan exo-β-1,4-mannosidase (EC 3.2.1.-);
Steryl β-glucosidase (EC 3.2.1.104);
Endoglycosylceramidase (EC 3.2.1.123);
Chitosanase (EC 3.2.1.132);
β-D-galactofuranosidase (EC 3.2.1.146);
β-primeverosidase (EC 3.2.1.149);
Oligoxyloglucan reducing-end-specific cellobiohydrolase (EC 3.2.1.150);
Xyloglucan-specific endo-β-1,4-glucanase / endo-xyloglucanase (EC 3.2.1.151);
Endo-β-1,6-galactanase (EC 3.2.1.164);
Hesperidin 6-O-α-L-rhamnosyl-β-glucosidase (EC 3.2.1.168);
β-glucosidase (EC 3.2.1.21);
β-galactosidase (EC 3.2.1.23);
β-mannosidase (EC 3.2.1.25);
Xylan β-1,4-xylosidase (EC 3.2.1.37);
Endo-β-1,3-glucanase / laminarinase (EC 3.2.1.39);
Endo-β-1,4-glucanase (EC 3.2.1.4);
β-glucosylceramidase (EC 3.2.1.45);
β-galactosylceramidase (EC 3.2.1.46);
β-N-acetylhexosaminidase (EC 3.2.1.52);
α-L-arabinofuranosidase (EC 3.2.1.55);
Exo-β-1,3-glucanase (EC 3.2.1.58);
Endo-β-1,3(4)-glucanase / lichenase-laminarinase (EC 3.2.1.6);
Lichenase / endo-β-1,3-1,4-glucanase (EC 3.2.1.73);
Exo-β-1,4-glucanase / cellodextrinase (EC 3.2.1.74);
Endo-β-1,6-glucanase (EC 3.2.1.75);
Endo-β-1,4-mannanase (EC 3.2.1.78);
Endo-β-1,4-xylanase (EC 3.2.1.8);
Cellobiohydrolase (EC 3.2.1.91);
Mechanism Retaining e
ClanGH-A
3D Structure Status( β / α ) 8 barrel
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental)
NoteOnce known as cellulase family A; many members have been assigned to subfamilies as described by Aspeborg et al. (2012) BMC Evol Biol. 12(1):186 (PMID: 22992189).
External resourcesCAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; NZYTech; PROZOMIX;
Statistics GenBank accession (31227); Uniprot accession (673); PDB accession (296); 3D entries (110); cryst (0)
Summary
Download GH5 (44486) Taxonomic display Structure (110) Characterized (624)
| 1 | ... | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 | ... | 245 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D Subf
 QNH35_08885   Bacillus pumilus B2_10 WHX46576.1     7
 LG951_08295   Bacillus pumilus BIM 171 UDF18178.1     7
 VP59_07445   Bacillus pumilus C4 ANT56640.1     7
 K4A85_01905   Bacillus pumilus EB130 QZD59784.1     7
 R0I01_02000   Bacillus pumilus EB68 WOP22253.1     7
 Q8W18_08365   Bacillus pumilus F12-21 WLP61234.1     7
 β-mannanase   Bacillus pumilus GBSW 19 AHF81566.1     7
 BS467_15785   Bacillus pumilus GLB197 APP17114.1     7
 ID12_13295   Bacillus pumilus GR-8 AKU32339.1     7
 Cel5S   Bacillus pumilus HY1 ACY72384.1     2
 endo-β-1,4-glucanase (fragment)   Bacillus pumilus IARI-SP-5 AGW99982.1     2
 ASM07_07620   Bacillus pumilus ku-bf1 AMB89777.1     7
 QPL77_07980   Bacillus pumilus Monterrey_S2 WIG33586.1     7
 MK860_08080   Bacillus pumilus MS32 WFO49112.1     7
 BW16_08670   Bacillus pumilus MTCC B6033 AHL71452.1     7
 SAMEA4076707_01656   Bacillus pumilus NCTC10337 SNV02448.1     7
 NPA43_07930   Bacillus pumilus NDY-10 UUD44160.1     7
 AKO65_15415   Bacillus pumilus NJ-M2 ALM29338.1     7
 AKO66_11740   Bacillus pumilus NJ-V ANY97356.1     7
 AMR71_11735   Bacillus pumilus NJ-V2 ALM45875.1     7
 H9S87_07710   Bacillus pumilus ONU 554 QNP17861.1     7
 BEN31_07990   Bacillus pumilus PDSLzg-1 AOC56743.1     7
 WAA16_07920   Bacillus pumilus S9 WWZ72963.1     7
 BPUM_1561   Bacillus pumilus SAFR-032 ABV62243.1     7
 GPS65_08550   Bacillus pumilus SF-4 QHQ76169.1     7
 UP15_08390   Bacillus pumilus SH-B11 AMM88977.1     7
 UP12_08105   Bacillus pumilus SH-B9 AMM97310.1     7
 BTUAT1_15770   Bacillus pumilus TUAT1 BAT48711.1     7
 HZ310_11005   Bacillus pumilus UAMX QLI78307.1     7
 VT48_08320   Bacillus pumilus W3 AKC66023.1     7
 DKE43_04285   Bacillus pumilus ZB201701 AZV52369.1     7
 M0696_09800   Bacillus rugosus A78.1 UPV80949.1     2
 NIZ90_07965   Bacillus safensis 1370ba1 USY30674.1     7
 M5E03_08360   Bacillus safensis AHB11 USD80685.1     7
 M5E02_08020   Bacillus safensis AHB2 USD84333.1     7
 BWL10_15385   Bacillus safensis BcP62 UDB50681.1     7
 B0X07_00650   Bacillus safensis Bcs96 UDB47719.1     7
 EI692_07830   Bacillus safensis BLXSC UQZ92883.1     7
 BRL64_08220   Bacillus safensis BRM1 ARD56165.1     7
 ORQ91_02180   Bacillus safensis BS-10L WBL29606.1     7
 QNH21_08110   Bacillus safensis CEW AP102 WHX84357.1     7
 QNH25_08125   Bacillus safensis CEW-AP100 WHX76900.1     7
 WNC56_08410   Bacillus safensis DMB13 WYZ12158.1     7
 JNE45_08115   Bacillus safensis F6 QRF33821.1     7
 RS87_08150   Bacillus safensis FO-36b AWI36699.1     7
 N4Q31_08195   Bacillus safensis GX-H6 UXC34024.1     7
 LXN49_08095   Bacillus safensis H31R-08 UIN51756.1     7
 BsIDN1_30480 (fragment)   Bacillus safensis IDN1 BBP89430.1     7
 V9W59_08345   Bacillus safensis JJ1041 WWY46181.1     7
 BSL056_08100   Bacillus safensis KCTC 12796BP APJ10920.1     7
 FX981_03751   Bacillus safensis PgKB20 QEK65481.1     7
 RA177_08170   Bacillus safensis PL23A WLW71085.1     7
 O0R49_08455   Bacillus safensis PLA 1006 WAT82369.1     7
 P5638_13925   Bacillus safensis PRO114 WEZ15210.1     7
 CS953_10685   Bacillus safensis sami AYJ90157.1     7
 PNF30_11115   Bacillus safensis SRCM125915 WCL56077.1     7
 BSA145_16070   Bacillus safensis U14-5 APT47251.1     7
 BSA171_11305   Bacillus safensis U17-1 APT54133.1     7
 BSA41_06410   Bacillus safensis U41 APT49591.1     7
 V6986_08120   Bacillus safensis yw6 WWT79410.1     7
 MXH81_08065   Bacillus safensis ZK-1 UPI93478.1     7
 JD965_09670   Bacillus siamensis B28 QQD83826.1     2
 IXY25_03525   Bacillus siamensis BZR 86 QPG18760.1     2
 LYZ33_09330   Bacillus siamensis GUWM35 UIO94268.1     2
 KI431_09060   Bacillus siamensis IMD4001 UXZ19638.1     2
 CWD84_11935   Bacillus siamensis SCSIO 05746 AUJ77469.1     2
 NNG64_08175   Bacillus siamensis WYJ-E14 UUA85760.1     2
 OM992_09635   Bacillus siamensis YB-1631 UZD75898.1     2
 endo-glucanase   Bacillus sonorensis BD92 QGW63294.1     2
 SK061_10005   Bacillus sonorensis PMC204 WPP39051.1     7
 SK061_12470   Bacillus sonorensis PMC204 WPP34538.1     2
 SK061_10000   Bacillus sonorensis PMC204 WPP38509.1     4
 S101395_02568   Bacillus sonorensis SRCM101395 ASB89075.1     2
 S101395_03069   Bacillus sonorensis SRCM101395 ASB89576.1     7
 S101395_03070   Bacillus sonorensis SRCM101395 ASB89577.1     4
 unnamed protein product   Bacillus sp. (in: firmicutes) CAD67813.1
ABH73763.1
CAH03186.1		     2
 β-mannanase   Bacillus sp. (in: firmicutes) AAQ31834.1     8
 endo-β-1,4-glucanase 3.2.1.4 Bacillus sp. (in: firmicutes) 22-28 BAA12744.1 Q45554   2
 endo-β-1,4-glucanase 3.2.1.4 Bacillus sp. (in: firmicutes) 5H BAA31712.1 O83012   2
 endo-1,4-β-glucanase, partial   Bacillus sp. (in: firmicutes) AGh1 QLI42581.1     2
 endo-β-1,4-glucanase, partial (BglH)   Bacillus sp. (in: firmicutes) B110 UAW20835.1     2
 BS34A_20090 (EglS)   Bacillus sp. (in: firmicutes) BS34A CEJ77430.1     2
 unnamed protein product   Bacillus sp. (in: firmicutes) CBS 669.93 AAE86309.1
AAV25062.1
CAD82874.1		     4
 cellulase (BCE103)   Bacillus sp. (in: firmicutes) CBS 670.93 CAB59165.1
AAV25061.1
CAB58698.1
CAD82873.1		   1LF1[A] 2
 endo-β-1,4-glucanase (Cel5L)   Bacillus sp. (in: firmicutes) KD1014 AYV97589.1     2
 ba103 (Man5A)   Bacillus sp. (in: firmicutes) KW1 QGN03632.1     7
 endo-β-1,4-glucanase B1 3.2.1.4 Bacillus sp. (in: firmicutes) N186-1 CAA83942.1 Q59232   2
 endo-β-1,4-glucanase, partial (CelD) (fragment)   Bacillus sp. (in: firmicutes) NZ-3 QEQ43012.1     2
 endo-β-1,4-glucanase, partial (CelD) (fragment)   Bacillus sp. (in: firmicutes) NZ-3 QEQ43012.1     2
 CJO35_09285   Bacillus sp. 1s-1 ASV15340.1     4
 CJO35_10335   Bacillus sp. 1s-1 ASV17692.1     2
 CJO35_09290   Bacillus sp. 1s-1 ASV15341.1     7
 BZ167_00180   Bacillus sp. 275 AQP94520.1     2
 JJ692_12995   Bacillus sp. 3a QSJ00013.1     7
 CelS 3.2.1.4 Bacillus sp. 79-23 AAC02536.1 O52731   2
 HXZ66_05620   Bacillus sp. A116_S68 UJW56931.1     4
 HXZ66_15100   Bacillus sp. A116_S68 UJW58648.1     2
 HXZ66_04760   Bacillus sp. A116_S68 UJW56771.1     35
 HXZ66_17480   Bacillus sp. A116_S68 UJW59071.1     8
 GD442_16685   Bacillus sp. A260 QGY36409.1     48
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