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Glycoside Hydrolase Family 5 / Subf 18

Activities in Sub Familyβ-mannosidase (EC 3.2.1.25);
Mechanism Retaining e
ClanGH-A
3D Structure Status( β / α ) 8 barrel
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental)
NoteOnce known as cellulase family A; many members have been assigned to subfamilies as described by Aspeborg et al. (2012) BMC Evol Biol. 12(1):186 (PMID: 22992189).
External resourcesCAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; NZYTech; PROZOMIX;
Statistics GenBank accession (733); Uniprot accession (5); PDB accession (12); 3D entries (5); cryst (0)
Summary
Download GH5_18 (728) Taxonomic display Structure (5) Characterized (5)
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Bacteria
Protein Name EC#Organism GenBankUniprotPDB/3DSubf
 SMD11_0766   Streptomyces albireticuli SMD11 ARZ66432.1     18
 SMD44_07664   Streptomyces alboflavus MDJK44 ARX88177.1     18
 CP975_31795   Streptomyces alboniger ATCC 12461 QEV21517.1     18
 N1H47_34685   Streptomyces albulus IFO14147 UWS75930.1     18
 DC74_7129   Streptomyces albulus NK660 AIA07557.1     18
 SLNHY_1504   Streptomyces albus BK3-25 AOU76195.1     18
 G3260_000656   Streptomyces albus CAS922 QID34808.1     18
 NR995_30590   Streptomyces albus DSM 40763 UVN58388.1     18
 SLNWT_1503   Streptomyces albus DSM 41398 AJE81879.1     18
 DUI70_1482   Streptomyces albus ZD11 AYN31985.1     18
 H9W91_32990   Streptomyces alfalfae XN-04 QUI35116.1     18
 SAM40697_6661   Streptomyces ambofaciens DSM 40697 ANB10614.1     18
 HCX60_02430   Streptomyces antibioticus DSM 41481 QIT48700.1     18
 G9272_03100   Streptomyces asoensis H2S5 QJT06607.1     18
 O1Q96_30815   Streptomyces aurantiacus Qhu-M197 WAU83702.1     18
 O1Q96_16610   Streptomyces aurantiacus Qhu-M197 WAU86293.1     18
 G3H79_03480   Streptomyces aureoverticillatus HN6 QIB42281.1     18
 SAV7274   Streptomyces avermitilis MA-4680 = NBRC 14893 BAC74985.1
NP_828450.1		     18
 SAVMC3_82480   Streptomyces avermitilis MC3 BBJ55619.1     18
 SBI_00829   Streptomyces bingchenggensis BCW-1 ADI03950.1     18
 GQF42_38615   Streptomyces broussonetiae T44 QHA08394.1     18
 EJC51_40460   Streptomyces brunneus CR22 AZP21810.1     18
 EJC51_36180   Streptomyces brunneus CR22 AZP21038.1     18
 DN051_07010   Streptomyces cadmiisoli ZFG47 AWW36418.1     18
 IHE65_38775   Streptomyces caniscabiei ID-03-3A WEO30234.1     18
 OG925_13215   Streptomyces canus NBC_01585 WSD85196.1     18
 OG925_08420   Streptomyces canus NBC_01585 WSD84319.1     18
 CP983_04890   Streptomyces chartreusis ATCC 14922 QEV66061.1     18
 HUT05_06165   Streptomyces chartreusis NA02069 QKZ16990.1     18
 IPT68_32500   Streptomyces chromofuscus DSM 40273 QOV44297.1     18
 STRCI_007066   Streptomyces cinnabarinus DSM 40467 WAZ25559.1     18
 SCO0949 or SCM11.04c   Streptomyces coelicolor A3(2) CAB61915.1
NP_625246.1		     18
 FQ762_04750   Streptomyces coelicolor A3(2) CFB_NBC_0001 QFI41191.1     18
 JCM4020_09490   Streptomyces coelicolor JCM 4020 BDD70329.1     18
 HCU77_04560   Streptomyces coelicolor M1154/pAMX4/pGP1416 QKN71059.1     18
 RE436_04620   Streptomyces coelicolor M22 WMT31729.1     18
 CP976_33465   Streptomyces coeruleorubidus ATCC 13740 QEV28548.1     18
 PV963_35085   Streptomyces coeruleorubidus DM WDV55215.1     18
 R5U08_04540   Streptomyces coeruleorubidus WT-48 WOT33459.1     18
 HGI09_05950   Streptomyces collinus L2 UJA13300.1     18
 HGI10_58150   Streptomyces collinus SQ UJA11834.1     18
 B446_31815   Streptomyces collinus Tu 365 AGS73167.1     18
 QU709_03615   Streptomyces coralus SX92 WLW50499.1     18
 QU709_09050   Streptomyces coralus SX92 WLW58389.1     18
 EJ357_04820   Streptomyces cyaneochromogenes MK-45 AZQ32851.1     18
 EJ357_35890   Streptomyces cyaneochromogenes MK-45 AZQ38173.1     18
 S1361_34505   Streptomyces cyanogenus S136 QTE02494.1     18
 BN159_1456   Streptomyces davaonensis JCM 4913 CCK25835.1     18
 L3078_06770   Streptomyces deccanensis KCTC 19241 ULR55872.1     18
 K7C20_33520   Streptomyces decoyicus NRRL 2666 QZY19538.1     18
 NEH16_00620   Streptomyces drozdowiczii MDA8-470 UZK52811.1     18
 M4V62_05750   Streptomyces durmitorensis MS405 UQT54642.1     18
 OJ254_25530   Streptomyces endophytica HNM0140 UZJ33037.1     18
 PS783_33195   Streptomyces enissocaesilis NBF 715 WDI22163.1     18
 GFH48_07565   Streptomyces fagopyri QMT-28 QFZ73139.1     18
 IM697_32900   Streptomyces ferrugineus CCTCC AA2014009 QOV34861.1     18
 QUY26_04525   Streptomyces flavofungini TRM90047 WJV44860.1     18
 J4032_16025   Streptomyces formicae 1H-GS9 UNM12821.1     18
 KY5_7386   Streptomyces formicae KY5 ATL32404.1     18
 D3X13_03260   Streptomyces fradiae NKZ-259 AYA15393.1     18
 H4W23_06520   Streptomyces gardneri ATCC 15439 QPK44296.1     18
 B1H19_36315   Streptomyces gilvosporeus F607 ARF58923.1     18
 C0216_07410   Streptomyces globosus LZH-48 AXE27344.1     18
 GCM10017557_09000   Streptomyces glomeroaurantiacus JCM 4677 BCL26041.1     18
 test1122_21230   Streptomyces gobiensis 1_25 UGY93984.1     18
 SGFS_103020 (fragment)   Streptomyces graminofaciens A-8890 BBC39008.1     18
 V9K83_01650   Streptomyces griseoaurantiacus XQ-29 WWY82984.1     18
 AVL59_16115   Streptomyces griseochromogenes ATCC 14511 ANP56544.1     18
 HEP81_07580   Streptomyces griseofuscus DSM 40191 QNT97812.1     18
 DWG14_02058 (fragment)   Streptomyces griseorubiginosus 3E-1 AYC37839.1     18
 ELQ87_04330   Streptomyces griseoviridis F1-27 AZS83604.1     18
 DDJ31_35025   Streptomyces griseoviridis K61 QCN89541.1     18
 K9S39_40000   Streptomyces halobius 3_2 UQA97232.1     18
 J2N69_33750   Streptomyces huasconensis D23 UFQ19535.1     18
 DWB77_02465   Streptomyces hundungensis BH38 AYG80334.1     18
 HOK021_43050 (fragment)   Streptomyces hygroscopicus HOK021 BDH13126.1     18
 SHJG_0530   Streptomyces hygroscopicus subsp. jinggangensis 5008 AEY85807.1     18
 SHJGH_0363   Streptomyces hygroscopicus subsp. jinggangensis TL01 AGF60029.1     18
 SHL15_8397   Streptomyces hygroscopicus subsp. limoneus KCTC 1717 ALO99347.1     18
 ABB07_03975   Streptomyces incarnatus NRRL 8089 AKJ09211.1     18
 KI385_39075   Streptomyces inhibens NRRL30439 UKY54227.1     18
 RI060_09180   Streptomyces janthinus JCM 4387 WND17503.1     18
 CP970_03260   Streptomyces kanamyceticus ATCC 12853 QEU90056.1     18
 KJK29_03350   Streptomyces koelreuteriae MG62 QWB21693.1     18
 KJK29_07275   Streptomyces koelreuteriae MG62 QWB22394.1     18
 P8A22_20420   Streptomyces laculatispora Mut2 WLQ42115.1     18
 SLAV_11005   Streptomyces lavendulae subsp. lavendulae CCM 3239 ATZ24069.1     18
 J3S85_02620   Streptomyces lavenduligriseus Tu901 WDM10535.1     18
 HA039_05170   Streptomyces liangshanensis QMT-12 QIQ01760.1     18
 STRLI_000922   Streptomyces libani subsp. libani DSM 40555 WAT95232.1     18
 JEQ17_40305   Streptomyces liliifuscus ZYC-3 QQM47184.1     18
 JEQ17_07635   Streptomyces liliifuscus ZYC-3 QQM46553.1     18
 GJU35_34715   Streptomyces lincolnensis B48 QMV12645.1     18
 SLCG_1944   Streptomyces lincolnensis LC-G AXG53099.1     18
 SLINC_6472   Streptomyces lincolnensis NRRL 2936 ANS68696.1     18
 SLITK23_09060   Streptomyces lividans TK23 BDE37661.1     18
 SLIV_33190   Streptomyces lividans TK24 AIJ17522.1     18
 LGI35_37290   Streptomyces longhuiensis BH-MK-02 UDM03503.1     18
 LGI35_39930   Streptomyces longhuiensis BH-MK-02 UDM03992.1     18
 EKH77_28105   Streptomyces luteoverticillatus CGMCC 15060 AZQ74557.1     18
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