Glycoside Hydrolase Family 5 / Subf 18

Activities in Sub Familyβ-mannosidase (EC 3.2.1.25);
Mechanism Retaining e
ClanGH-A
3D Structure Status( β / α ) 8 barrel
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental)
NoteOnce known as cellulase family A; many members have been assigned to subfamilies as described by Aspeborg et al. (2012) BMC Evol Biol. 12(1):186 (PMID: 22992189).
External resourcesCAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; NZYTech; PROZOMIX;
Statistics GenBank accession (733); Uniprot accession (5); PDB accession (12); 3D entries (5); cryst (0)
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 |
Bacteria
Protein Name EC#Organism GenBankUniprotPDB/3DSubf
 NCG97_03720   Streptomyces lydicamycinicus MMS22-DDSA8 URZ99989.1     18
 SL103_21365   Streptomyces lydicus 103 AOP48446.1     18
 LJ741_34080   Streptomyces lydicus M01 UEG95140.1     18
 DDE74_36230   Streptomyces lydicus WYEC 108 AZS75621.1     18
 K7I03_02900   Streptomyces mobaraensis DSM 40587 UBI35518.1     18
 J7W19_29645   Streptomyces mobaraensis NBRC 13819 = DSM 40847 QTT76996.1     18
 POD33_34610   Streptomyces moderatus DT446 WCH96990.1     18
 GO605_18005   Streptomyces murinus CR-43 UWW92516.1     18
 ME763_36320   Streptomyces murinus JS029 WDO10668.1     18
 WEB32_29360   Streptomyces netropsis M-141 WXH42122.1     18
 DC008_30540   Streptomyces nigra 452 AWE53593.1     18
 STRNI_000909   Streptomyces nigrescens DSM 40276 WAU02841.1     18
 HEK616_41760   Streptomyces nigrescens HEK616 BDM70689.1     18
 CP978_05375   Streptomyces nodosus ATCC 14899 QEV38038.1     18
 SNOD_04995   Streptomyces nodosus ATCC 14899 AJE39452.1     18
 JYK04_06185   Streptomyces nojiriensis JCM 3382 QTI48321.1     18
 JNO44_38320   Streptomyces noursei A-2-1 QRX95866.1     18
 SNOUR_06490   Streptomyces noursei ATCC 11455 ANZ14617.1     18
 SAZ_36960   Streptomyces noursei ZPM AKA07371.1     18
 MMU79_14495   Streptomyces olivaceus B-81 WFB84439.1     18
 QZH56_03605   Streptomyces olivoreticuli ZZ-21 WKK24730.1     18
 B1H29_04150   Streptomyces pactum ACT12 AQS66237.1     18
 DVK44_29925   Streptomyces paludis GSSD-12 AXG81212.1     18
 DVK44_33230   Streptomyces paludis GSSD-12 AXG81785.1     18
 Spa2297_28905   Streptomyces parvulus 2297 ANJ10645.1     18
 OHB35_43150   Streptomyces phaeochromogenes NBC 01752 WSD21919.1     18
 OHB35_07690   Streptomyces phaeochromogenes NBC 01752 WSD13124.1     18
 OG931_07300   Streptomyces phaeochromogenes NBC_00186 WRZ27564.1     18
 OG931_42870   Streptomyces phaeochromogenes NBC_00186 WRZ36475.1     18
 F9278_05335   Streptomyces phaeolivaceus GY16 QFQ95697.1     18
 LK06_001720   Streptomyces pluripotens MUSC 135 ARP73894.1     18
 LK07_02800   Streptomyces pluripotens MUSC 137 ASN28157.1     18
 SPRI_6676   Streptomyces pristinaespiralis HCCB 10218 ALC24982.1     18
 H3L99_03375   Streptomyces pristinaespiralis PR11 QMU12736.1     18
 BFF78_05005   Streptomyces puniciscabiei TW1S1 AOR36892.1     18
 FGW37_28115   Streptomyces rectiverticillatus B15-08 QLE74945.1     18
 TUE45_00150   Streptomyces reticuli CUW25440.1     18
 CP984_24010   Streptomyces rimosus ATCC 10970 QEV77647.1     18
 V519_001020   Streptomyces rimosus R6-500 QGY71095.1     18
 SRIM_016815   Streptomyces rimosus subsp. rimosus ATCC 10970 QST85957.1     18
 SRIMDV3_21360   Streptomyces rimosus subsp. rimosus DV3 UTJ14794.1     18
 SRIMHP_21465   Streptomyces rimosus subsp. rimosus HP126 UTH96697.1     18
 SRIMR7_24100   Streptomyces rimosus subsp. rimosus R7 UNZ05243.1     18
 FMM49_24575   Streptomyces rimosus subsp. rimosus SRI-4018v0 QTL91811.1     18
 CTZ40_24045   Streptomyces rimosus WT5260 QDA06371.1     18
 SRO_7253   Streptomyces rochei 7434AN4 BBC98429.1     18
 TR631_32580   Streptomyces rochei D21E05 WQC16302.1     18
 P7W03_31320   Streptomyces rochei JK1 WMC89816.1     18
 RBH85_04220   Streptomyces rochei S32 WMI56087.1     18
 RGF97_02595   Streptomyces roseicoloratus T14 WMX43970.1     18
 IAG44_37620   Streptomyces roseirectus CRXT-G-22 QNP74613.1     18
 HUT11_03855   Streptomyces seoulensis A01 QKW25363.1     18
 A7J05_04260   Streptomyces silaceus ACCC40021 APY85054.1     18
 P8T65_41300   Streptomyces sp. 11x1 WNZ14773.1     18
 SAMN05428941_1007   Streptomyces sp. 2114.2 SDS71412.1     18
 GZL_01518   Streptomyces sp. 769 AJC54118.1     18
 T261_0639   Streptomyces sp. A02 AJT62328.1     18
 HRD51_35420   Streptomyces sp. A1-5 UJB45374.1     18
 K5X85_31150   Streptomyces sp. A144 UAX57154.1     18
 IOD14_10935   Streptomyces sp. A2-16 QUC63313.1     18
 IOD14_15925   Streptomyces sp. A2-16 QUC58169.1     18
 N7U49_06805   Streptomyces sp. AD2-2 UXX92132.1     18
 EES41_26795   Streptomyces sp. ADI95-16 AYV30331.1     18
 DKB30_33360   Streptomyces sp. Ae707_A7 QNF65995.1     18
 RPQ07_32550   Streptomyces sp. AM2-3-1 WNO76055.1     18
 RPQ02_31630   Streptomyces sp. AM8-1-1 WNO68047.1     18
 CVT30_40270   Streptomyces sp. AMCC400023 UJV45253.1     18
 M6G09_32495   Streptomyces sp. B146 WGK49941.1     18
 RI578_04430   Streptomyces sp. BB1-1-1 WND33585.1     18
 K2224_29590   Streptomyces sp. BHT-5-2 QZL07420.1     18
 WAB15_36225   Streptomyces sp. BP-8 WXK81021.1     18
 OH540_04440   Streptomyces sp. BPPL-273 WHM29318.1     18
 QIY60_26950   Streptomyces sp. BPTC-684 WHM40132.1     18
 JIX56_40300   Streptomyces sp. CA-210063 UUU37321.1     18
 C2142_32270   Streptomyces sp. CB01881 AUY52806.1     18
 C4J65_01285   Streptomyces sp. CB09001 AXL87093.1     18
 L6J92_15160   Streptomyces sp. CB09030 UOG80444.1     18
 NI25_03335   Streptomyces sp. CCM_MD2014 AIV32684.1     18
 AS200_07935   Streptomyces sp. CdTB01 ALV31970.1     18
 RJD14_25640   Streptomyces sp. CGMCC 4.1456 WNF65766.1     18
 VJ737_09305   Streptomyces sp. CGMCC 4.1772 WRT97865.1     18
 PET44_24190   Streptomyces sp. CGMCC 4.1796 WBY22456.1     18
 Q2K21_19730   Streptomyces sp. CGMCC 4.7035 WNC00120.1     18
 NNW99_03370   Streptomyces sp. CRCS-T-1 UUA12243.1     18
 NNW99_07310   Streptomyces sp. CRCS-T-1 UUA12962.1     18
 NNW98_03370   Streptomyces sp. CRLD-Y-1 UUA04619.1     18
 NNW98_07310   Streptomyces sp. CRLD-Y-1 UUA05336.1     18
 JIX55_08370   Streptomyces sp. DSM 40750 UUU20319.1     18
 HB370_34770   Streptomyces sp. DSM 40868 QIS74513.1     18
 EASAB2608_00972   Streptomyces sp. EAS-AB2608 NBRC 114648 BCM65638.1     18
 B1K54_26600   Streptomyces sp. fd1-xmd AQT74744.1     18
 KK483_33115   Streptomyces sp. FIT100 UUN30637.1     18
 A6P39_008035   Streptomyces sp. FXJ1.172 WEO93969.1     18
 Q7C01_15370   Streptomyces sp. FXY-T5 WMD05689.1     18
 NUT86_36990   Streptomyces sp. G7(2002) WDT59176.1     18
 KQY30_06150   Streptomyces sp. GMY02 QXE33934.1     18
 C1703_30575   Streptomyces sp. Go-475 AXE89370.1     18
 KBP30_06505   Streptomyces sp. Go40/10 Go 40/10 UFR00847.1     18
 LUX31_02850   Streptomyces sp. GQFP UIX29046.1     18
 LUX31_18020   Streptomyces sp. GQFP UIX31778.1     18
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