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Glycoside Hydrolase Family 5 / Subf 18

Activities in Sub Familyβ-mannosidase (EC 3.2.1.25);
Mechanism Retaining e
ClanGH-A
3D Structure Status( β / α ) 8 barrel
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental)
NoteOnce known as cellulase family A; many members have been assigned to subfamilies as described by Aspeborg et al. (2012) BMC Evol Biol. 12(1):186 (PMID: 22992189).
External resourcesCAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; NZYTech; PROZOMIX;
Statistics GenBank accession (733); Uniprot accession (5); PDB accession (12); 3D entries (5); cryst (0)
Summary
Download GH5_18 (728) Taxonomic display Structure (5) Characterized (5)
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Bacteria
Protein Name EC#Organism GenBankUniprotPDB/3DSubf
 J7M33_06760   Bifidobacterium longum K15 QTL75153.1     18
 I3K77_06185   Bifidobacterium longum K2-21-4 QUI43929.1     18
 J7M31_06770   Bifidobacterium longum K5 QTL68013.1     18
 PIB40_08630   Bifidobacterium longum LBUX23 WCE37196.1     18
 LCQ81_09160   Bifidobacterium longum NBRC 114370 UBS39695.1     18
 β-mannosidase (BlMan5B; BL1333) (BlMan5B) 3.2.1.25 Bifidobacterium longum NCC2705 AAN25133.1
NP_696497.1		 Q8G4P5   18
 SAMN04489749_0829   Bifidobacterium longum Su859 SDO44614.1     18
 BLIF_1312   Bifidobacterium longum subsp. infantis 157F BAJ71452.1     18
 Blon_2377   Bifidobacterium longum subsp. infantis ATCC 15697 = JCM 1222 = DSM 20088 ACJ53432.1   7LQX[A] 18
 BLIJ_2448   Bifidobacterium longum subsp. infantis ATCC 15697 = JCM 1222 = DSM 20088 BAJ70025.1     18
 HUE60_11685   Bifidobacterium longum subsp. infantis BB-02 UPT10190.1     18
 NUU11_11995   Bifidobacterium longum subsp. infantis BB-02 UUY28169.1     18
 EE567_010810   Bifidobacterium longum subsp. infantis Bi-26 QKY14223.1     18
 KDJ92_10645   Bifidobacterium longum subsp. infantis BINF QUF87966.1     18
 RY67_1643   Bifidobacterium longum subsp. infantis BT1 ALE09655.1     18
 RY67_518   Bifidobacterium longum subsp. infantis BT1 ALE08581.1     18
 BL1347_00205   Bifidobacterium longum subsp. infantis JCM 11347 QOL44583.1     18
 BL1660_02565   Bifidobacterium longum subsp. infantis JCM 11660 QOL47075.1     18
 BLI009_01620   Bifidobacterium longum subsp. infantis JCM 7009 QSP97892.1     18
 BLI010_07880   Bifidobacterium longum subsp. infantis JCM 7010 QTB92408.1     18
 BLI011_01580   Bifidobacterium longum subsp. infantis JCM 7011 QSZ18139.1     18
 MT990_11985   Bifidobacterium longum subsp. infantis JRPT UOG10698.1     18
 NCTC11817_02520   Bifidobacterium longum subsp. infantis NCTC11817 VEG44600.1     18
 HUE59_04405   Bifidobacterium longum subsp. infantis NLS UPT10957.1     18
 HUE61_04440   Bifidobacterium longum subsp. infantis PI_002 UPT07820.1     18
 HUE62_03685   Bifidobacterium longum subsp. infantis PI_003 UPT04368.1     18
 HUE63_04405   Bifidobacterium longum subsp. infantis PI_004 UPT02436.1     18
 HUE64_10675   Bifidobacterium longum subsp. infantis PI_005 UPT33779.1     18
 HUE65_04510   Bifidobacterium longum subsp. infantis PI_006 UPT13026.1     18
 HUE66_04405   Bifidobacterium longum subsp. infantis PI_007 UPT30682.1     18
 HUE67_01945   Bifidobacterium longum subsp. infantis PI_008 UPT28171.1     18
 HUE68_04405   Bifidobacterium longum subsp. infantis PI_009 UPT26520.1     18
 HUE69_08495   Bifidobacterium longum subsp. infantis PI_010 UPT25102.1     18
 O0R44_10750   Bifidobacterium longum subsp. infantis Y46 WAT12268.1     18
 β-1,4-mannosidase (BlGH5_18; HMPREF0175_1989) 3.2.1.25 Bifidobacterium longum subsp. longum ATCC 55813 EEI79871.1 C2GY91 7LR1[A,B,C,D]
7LR2[A,B,C,D]
7LR6[A,B,C,D] 		18
 G8B11_04075   Bifidobacterium longum subsp. longum B1 UNL81573.1     18
 G8B12_00460   Bifidobacterium longum subsp. longum B2 UNL70560.1     18
 G8B14_04325   Bifidobacterium longum subsp. longum B4 UNL67225.1     18
 G8B15_04515   Bifidobacterium longum subsp. longum B5 UNL65246.1     18
 BBMN68_220   Bifidobacterium longum subsp. longum BBMN68 ADQ02913.1     18
 BCBL_1298   Bifidobacterium longum subsp. longum BCBL-583 UAU38166.1     18
 DVB78_06135   Bifidobacterium longum subsp. longum BORI AXF98754.1     18
 BBL306_1348   Bifidobacterium longum subsp. longum CCUG30698 ALO74877.1     18
 BIL_06980   Bifidobacterium longum subsp. longum F8 CBK70291.1     18
 BLGT_06810   Bifidobacterium longum subsp. longum GT15 AIW44813.1     18
 BL1343_01690   Bifidobacterium longum subsp. longum JCM 11343 QOL41856.1     18
 BL7050_07340   Bifidobacterium longum subsp. longum JCM 7050 QOL38152.1     18
 BL7055_07815   Bifidobacterium longum subsp. longum JCM 7055 QOL58703.1     18
 BLJ_1281   Bifidobacterium longum subsp. longum JDM301 ADH00732.1     18
 BL5915_09510   Bifidobacterium longum subsp. longum KCTC 5915 QOL54995.1     18
 LCQ52_07290   Bifidobacterium longum subsp. longum NBRC 114494 UCH54774.1     18
 B8809_1134   Bifidobacterium longum subsp. longum NCIMB8809 ALO72805.1     18
 DND34_07480   Bifidobacterium longum subsp. longum YS108R QLE15481.1     18
 BLS995_01055   Bifidobacterium longum subsp. suillum JCM 19995 QSG87100.1     18
 BLS605_01885   Bifidobacterium longum subsp. suillum KCTC 15605 QXT31529.1     18
 LZF93_06725   Bifidobacterium longum T1 UIP48984.1     18
 M1764_03490   Bifidobacterium longum W13 UPW87014.1     18
 ESN35_03475   Bifidobacterium pullorum subsp. gallinarum CACC 514 QAY32595.1     18
 BBSC_1812   Bifidobacterium scardovii JCM 12489 = DSM 13734 BAQ31892.1     18
 OZX62_07040   Bifidobacterium sp. ESL0690 WEV46202.1     18
 OZX64_03030   Bifidobacterium sp. ESL0704 WEV53710.1     18
 OZX67_06815   Bifidobacterium sp. ESL0728 WEV58520.1     18
 MMB48_10835   Bifidobacterium sp. FKU UZE98993.1     18
 KIM372_11470   Bombiscardovia nodaiensis Kim37-2 BDR53240.1     18
 CFK39_00935   Brachybacterium avium VR2415 ASK64645.1     18
 Bfae_10930   Brachybacterium faecium DSM 4810 ACU84941.1     18
 CFK41_08345   Brachybacterium ginsengisoli DCY80 ATG54776.1     18
 NLU66_11495   Brachybacterium rhamnosum NBEC-018 UVY82854.1     18
 DWV08_02740   Brachybacterium saurashtrense DSM 23186 AXK44646.1     18
 BH708_13780   Brachybacterium sp. P6-10-X1 APX33606.1     18
 BH708_03855   Brachybacterium sp. P6-10-X1 APX32004.1     18
 CFK38_10445   Brachybacterium vulturis VM2412 ATG51890.1     18
 β-mannosidase (Caci_2257) 3.2.1.25 Catenulispora acidiphila DSM 44928 ACU71175.1 C7QJF2   18
 KG102_18215   Cellulomonas fengjieae zg-ZUI188 QVI65978.1     18
 NP075_15265   Cellulomonas wangsupingiae zg-Y908 UUI64462.1     18
 N8J89_36015   Crossiella sp. CA-258035 WHT18461.1     18
 N8J89_37760   Crossiella sp. CA-258035 WHT18792.1     18
 QPK07_05140   Curtobacterium citreum A02 WIJ46352.1     18
 NY058_05470   Curtobacterium flaccumfaciens GBBC3198 UWD80231.1     18
 NY057_05640   Curtobacterium flaccumfaciens GBBC3199 UWD83726.1     18
 N8D74_11900   Curtobacterium flaccumfaciens HS17 UXN24268.1     18
 N8D75_07815   Curtobacterium flaccumfaciens HS27 UXN30145.1     18
 NY059_05145   Curtobacterium flaccumfaciens pv. betae GBBC3146 UWD87086.1     18
 N3C65_14155   Curtobacterium flaccumfaciens pv. betae IRBAB180506 UWT73942.1     18
 N8D77_16685   Curtobacterium flaccumfaciens pv. flaccumfaciens AGQB44 UXN21748.1     18
 WDV91_05610   Curtobacterium flaccumfaciens pv. flaccumfaciens ARGTr 5-2 WXF92151.1     18
 JG551_001040   Curtobacterium flaccumfaciens pv. flaccumfaciens BRIP:70606 QVG67072.1     18
 JG550_001052   Curtobacterium flaccumfaciens pv. flaccumfaciens BRIP:70614 QTR91768.1     18
 FK523_05120   Curtobacterium flaccumfaciens pv. flaccumfaciens Cff1037 QKS86978.1     18
 K0028_05730   Curtobacterium flaccumfaciens pv. flaccumfaciens DSM 20129 QYI98410.1     18
 GBG65_12350   Curtobacterium flaccumfaciens pv. flaccumfaciens P990 QFS79963.1     18
 OE229_07980   Curtobacterium flaccumfaciens pv. poinsettiae AGQB46 UYC82386.1     18
 N8D76_07390   Curtobacterium flaccumfaciens pv. poinsettiae LMG 3711 UXN16501.1     18
 N8D78_07515   Curtobacterium flaccumfaciens pv. poinsettiae LMG 3716 UXN19950.1     18
 Q9Q99_18835 (fragment)   Curtobacterium flaccumfaciens W004 WNY33873.1     18
 JN350_08500   Curtobacterium sp. 24E2 QSB24560.1     18
 JN350_06345   Curtobacterium sp. 24E2 QSB24260.1     18
 QPJ90_17435   Curtobacterium sp. 458 WJY00052.1     18
 GA0004736_1675   Curtobacterium sp. 9128 SBN62767.1     18
 MXD64_05210   Curtobacterium sp. Arg-1 UXZ58781.1     18
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