Activities in Sub Family	β-mannosidase (EC 3.2.1.25);
Mechanism	Retaining e
Clan	GH-A
3D Structure Status	( β / α ) 8 barrel
Catalytic Nucleophile/Base	Glu (experimental)
Catalytic Proton Donor	Glu (experimental)
Note	Once known as cellulase family A; many members have been assigned to subfamilies as described by Aspeborg et al. (2012) BMC Evol Biol. 12(1):186 (PMID: 22992189).
External resources	CAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)	MEGAZYME; NZYTech; PROZOMIX;
Statistics	GenBank accession (733); Uniprot accession (5); PDB accession (12); 3D entries (5); cryst (0)

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Bacteria
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D	Subf
GR130_25425		Streptomyces sp. GS7	QHC24225.1			18
GR129_01030		Streptomyces sp. HF10	QHC27652.1			18
MQE23_11025		Streptomyces sp. HP-A2021	UOB15577.1			18
M1P56_21010		Streptomyces sp. HU2014	UQI46650.1			18
N8I86_32235		Streptomyces sp. HUAS 14-6	UXY38982.1			18
N8I87_35430		Streptomyces sp. HUAS 15-9	UXY31313.1			18
PGH47_37545		Streptomyces sp. HUAS 31	WCE01064.1			18
QRN89_03270		Streptomyces sp. HUAS CB01	WJY48907.1			18
Q3Y68_03070		Streptomyces sp. HUAS CX7	WKX17074.1			18
R2D22_01660		Streptomyces sp. HUAS YS2	WOX20164.1			18
DRB96_42080		Streptomyces sp. ICC1	AWZ17569.1			18
DRB89_42000		Streptomyces sp. ICC4	AWZ09883.1			18
G7Z12_03550		Streptomyces sp. ID38640	QIK05258.1			18
F1D59_09235		Streptomyces sp. INR7	QNE24920.1			18
RLT58_18780		Streptomyces sp. ITFR-16	WNI23834.1			18
RLT59_19630		Streptomyces sp. ITFR-6	WNI30746.1			18
PPN52_33700		Streptomyces sp. JCM 35825	WCL89154.1			18
KJK32_39905		Streptomyces sp. JCM17656	QWA25294.1			18
NOO62_35670		Streptomyces sp. Je 1-369	WAL99349.1			18
SLV14_000814		Streptomyces sp. Je 1-4	UYB38453.1			18
R9806_02645		Streptomyces sp. KN37	WPO69608.1			18
D1J63_03180		Streptomyces sp. KPB2	AZM74077.1			18
DKB27_01775		Streptomyces sp. KY2	QNF54037.1			18
MUK60_06515		Streptomyces sp. LRE541	UPZ27497.1			18
LRS74_31655		Streptomyces sp. LX-29	WFB11940.1			18
M6G08_21785		Streptomyces sp. M92	WCN04527.1			18
M444_25515		Streptomyces sp. Mg1	AKL68224.1			18
STRMOE7_34330		Streptomyces sp. MOE7	ARH94536.1			18
KGS77_20725		Streptomyces sp. MST-110588	UNO44080.1			18
P8A18_15695		Streptomyces sp. Mut1	WLQ34789.1			18
R2B38_38490		Streptomyces sp. N50	WOX14372.1			18
R2B38_32785		Streptomyces sp. N50	WOX13313.1			18
HUT19_38360		Streptomyces sp. NA02950	QKV96844.1			18
HUT15_02960		Streptomyces sp. NA03103	QKW59568.1			18
HUT18_27390		Streptomyces sp. NA04227	QKW09562.1			18
JIW86_12960		Streptomyces sp. NBC00162	UUU39636.1			18
OG428_30680		Streptomyces sp. NBC_01422	WUY00606.1			18
OG290_00855		Streptomyces sp. NBC_01423	WUX88395.1			18
OG906_10180		Streptomyces sp. NBC_01426	WUX81736.1			18
OG406_07385		Streptomyces sp. NBC_01428	WUX73595.1			18
OG627_05325		Streptomyces sp. NBC_01429	WUX66401.1			18
OG522_11915		Streptomyces sp. NBC_01431	WUX59764.1			18
OG574_04895		Streptomyces sp. NBC_01445	WSE02778.1			18
OG574_07860		Streptomyces sp. NBC_01445	WSE03314.1			18
DKG71_38990		Streptomyces sp. NEAU-S7GS2	AWN31267.1			18
HZZ00_20165		Streptomyces sp. NEAU-sy36	QLJ03070.1			18
DEH18_19970		Streptomyces sp. NHF165	QHF95747.1			18
QR97_37890		Streptomyces sp. PBH53	AKN74717.1			18
AW27_008235		Streptomyces sp. PCS3-D2	WKV71516.1			18
V2W30_35280		Streptomyces sp. Q6	WWQ68078.1			18
GPZ77_04445		Streptomyces sp. QHH-9511	QGZ52763.1			18
HYQ63_02210		Streptomyces sp. Rer75	QLH19603.1			18
M4D82_24650		Streptomyces sp. RerS4	UQX03315.1			18
FNV59_45665		Streptomyces sp. RLB1-8	QDO64435.1			18
FNV58_46630		Streptomyces sp. RLB1-9	QDO02433.1			18
FNV62_45020		Streptomyces sp. RLB3-17	QDO44301.1			18
FNV60_43415		Streptomyces sp. RLB3-5	QDO54190.1			18
FNV61_46180		Streptomyces sp. RLB3-6	QDN91914.1			18
HEP85_33995		Streptomyces sp. RPA4-2	QIY65673.1			18
FNV63_45235		Streptomyces sp. S1A1-3	QDO34291.1			18
FNV65_45215		Streptomyces sp. S1A1-8	QDO24168.1			18
HEP87_45790		Streptomyces sp. S1D4-11	QIZ02137.1			18
FNV66_44935		Streptomyces sp. S1D4-14	QDN71733.1			18
FNV67_46085		Streptomyces sp. S1D4-20	QDN61680.1			18
FNV68_47250		Streptomyces sp. S1D4-23	QDO12740.1			18
A8713_28445		Streptomyces sp. SAT1	ANH94624.1			18
SBE_005646		Streptomyces sp. SBE_14.2	WBO82612.1			18
PS467_40530		Streptomyces sp. SCA4-21	WNF01189.1			18
V1460_16865		Streptomyces sp. SCSIO 30461	WWR51410.1			18
C1N79_31850		Streptomyces sp. SGAir0924	QCR50815.1			18
B6R96_09720		Streptomyces sp. Sge12	ARE74178.1			18
C8250_009785		Streptomyces sp. So13.3	QNA72155.1			18
E5N77_32230		Streptomyces sp. SS52	QCB25964.1			18
A7X85_05970		Streptomyces sp. ST1015	QZZ25852.1			18
GEV49_04720		Streptomyces sp. SYP-A7193	QFX80290.1			18
PBV52_37545		Streptomyces sp. T12	WDF44859.1			18
PBV52_43625		Streptomyces sp. T12	WDF43197.1			18
SAMN05216371_6717		Streptomyces sp. TLI_053	SDT81587.1			18
BSL84_24760		Streptomyces sp. TN58	APU42518.1			18
GLX30_32780		Streptomyces sp. Tu 2975	QIP88003.1			18
MCU78_02930		Streptomyces sp. TYQ1024	UKW28110.1			18
KE639_06728		Streptomyces sp. V17-9	QUW95459.1			18
EZV63_33115		Streptomyces sp. VN1	QIP74071.1			18
Q3V23_30465		Streptomyces sp. VNUA116	WKU48037.1			18
Q3101_29835		Streptomyces sp. VNUA74	WML83799.1			18
D1J60_26520		Streptomyces sp. W1SF4	AZM91596.1			18
DLM49_05860		Streptomyces sp. WAC 01438	AZM59146.1			18
DMA15_34080		Streptomyces sp. WAC 01529	AZM56978.1			18
QHG49_00830		Streptomyces sp. WP-1	WKE67679.1			18
StreXyl84_07600		Streptomyces sp. Xyl84	BFD81359.1			18
C9F11_34540		Streptomyces sp. YIM 121038	QCX80491.1			18
CP982_35455		Streptomyces spectabilis ATCC 27465	QEV63350.1			18
FH965_33835		Streptomyces spectabilis NRRL 2792	QDQ14918.1			18
LXH13_34405		Streptomyces spinosirectus CRSS-Y-16	UIR21822.1			18
DDQ41_09690		Streptomyces spongiicola HNM0071	AWK09149.1			18
CP968_09100		Streptomyces subrutilus ATCC 27467	QEU78424.1			18
DDW44_01210		Streptomyces tirandamycinicus HNM0039	AWI27544.1			18
MMF93_31120		Streptomyces tubbatahanensis DSD3025	UNT00426.1			18
DEJ47_34255		Streptomyces venezuelae ATCC 14583	QES30809.1			18
DEJ48_03835		Streptomyces venezuelae ATCC 14584	QES38776.1			18
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