Glycoside Hydrolase Family 33

Activities in Familysialidase or neuraminidase (EC 3.2.1.18); trans-sialidase (EC 2.4.1.-); anhydrosialidase (EC 4.2.2.15); Kdo hydrolase (EC 3.2.1.-); 2-keto-3-deoxynononic acid hydrolase / KDNase (EC 3.2.1.-)
Mechanism Retaining
ClanGH-E
3D Structure Status6-fold β-propeller
Catalytic Nucleophile/BaseTyr+Glu
Catalytic Proton DonorNot known
External resourcesHOMSTRAD;
Commercial Enzyme Provider(s)MEGAZYME;
Statistics GenBank accession (6329); Uniprot accession (681); PDB accession (152); 3D entries (21); cryst (0)
All (6088) Archaea (1) Bacteria (5613) Eukaryota (431) Viruses (37) unclassified (6) Structure (21) Characterized (97)
| 1 | ... | 48 | 49 | 50 | 51 | 52 | 53 | 54 | 55 | 56 | ... | 58 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 BFF78_08635   Streptomyces puniciscabiei TW1S1 AOR31101.1    
 BFF78_28390   Streptomyces puniciscabiei TW1S1 AOR34447.1    
 A4E84_11690   Streptomyces qaidamensis S10(2016) AMW10120.1    
 A4E84_33700   Streptomyces qaidamensis S10(2016) AMW14014.1    
 M271_35050   Streptomyces rapamycinicus NRRL 5491 AGP58418.1    
 M271_07500   Streptomyces rapamycinicus NRRL 5491 AGP53120.1    
 neuraminidase   Streptomyces rapamycinicus NRRL 5491 AGP54140.1    
 TUE45_07154 (Neda_3)   Streptomyces reticuli CUW32405.1    
 TUE45_03121 (Neda_2)   Streptomyces reticuli CUW28387.1    
 TUE45_02825 (Neda_1)   Streptomyces reticuli CUW28095.1    
 CP984_29495   Streptomyces rimosus ATCC 10970 QEV78556.1    
 CP984_29495   Streptomyces rimosus ATCC 10970 QEV78556.1    
 CP984_06685   Streptomyces rimosus ATCC 10970 QEV74751.1    
 CP984_06685   Streptomyces rimosus ATCC 10970 QEV74751.1    
 V519_034650   Streptomyces rimosus R6-500 QGY70331.1    
 V519_022885   Streptomyces rimosus R6-500 QGY68383.1    
 CTZ40_29530   Streptomyces rimosus WT5260 QDA07275.1    
 CTZ40_06710   Streptomyces rimosus WT5260 QDA03471.1    
 SRO_4931   Streptomyces rochei 7434AN4 BBC96107.1    
 SRO_1359   Streptomyces rochei 7434AN4 BBC92535.1    
 A7J05_25630   Streptomyces silaceus ACCC40021 APY88614.1    
 A7J05_05955   Streptomyces silaceus ACCC40021 APY85328.1    
 CGL27_15120   Streptomyces sp. 11-1-2 ASQ94228.1    
 CGL27_36225   Streptomyces sp. 11-1-2 ASQ97747.1    
 CGL27_41180   Streptomyces sp. 11-1-2 ASQ98581.1    
 SAMN05428941_6626   Streptomyces sp. 2114.2 SDT79140.1    
 SAMN06272775_5075   Streptomyces sp. 2323.1 SOE14111.1    
 SAMN06272775_6207   Streptomyces sp. 2323.1 SOE15281.1    
 SAMN06272775_1119   Streptomyces sp. 2323.1 SOE10071.1    
 SAMN05444521_7759   Streptomyces sp. 3214.6 SHI51548.1    
 ASR50_28895   Streptomyces sp. 4F ALV53033.1    
 C3K23_02425   Streptomyces sp. 604F QHV83827.1    
 neuraminidase   Streptomyces sp. 769 AJC54865.1    
 T261_6984   Streptomyces sp. A02 AJT68586.1    
 neuraminidase   Streptomyces sp. A02 AJT63325.1    
 T261_5894   Streptomyces sp. A02 AJT67510.3
AJT67510.1
AJT67510.2
   
 EES41_21150 (NedA)   Streptomyces sp. ADI95-16 AYV29221.1    
 C4J65_29800   Streptomyces sp. CB09001 AXL92020.1    
 C4J65_31815   Streptomyces sp. CB09001 AXL92354.1    
 NI25_34220   Streptomyces sp. CCM_MD2014 AIV37956.1    
 AS200_10380   Streptomyces sp. CdTB01 ALV38485.1    
 AS200_29915   Streptomyces sp. CdTB01 ALV35791.1    
 AS200_31520   Streptomyces sp. CdTB01 ALV36071.1    
 ABE83_13020   Streptomyces sp. CFMR 7 ALC27916.1    
 neuraminidase   Streptomyces sp. CMB-StM0423 AUH43077.1    
 CXR04_30015   Streptomyces sp. CMB-StM0423 AUH43847.1    
 AA958_27020   Streptomyces sp. CNQ-509 AKH85286.1    
 AA958_04495   Streptomyces sp. CNQ-509 AKH81573.1    
 neuraminidase   Streptomyces sp. CNQ-509 AKH82377.1    
 SFR_6663   Streptomyces sp. FR-008 ALM43278.1    
 GR131_01245   Streptomyces sp. GF20 QHC14161.1    
 C1703_10640 (Neda1)   Streptomyces sp. Go-475 AXE85460.1    
 C1703_33275 (Neda2)   Streptomyces sp. Go-475 AXE89910.1    
 GR130_08850   Streptomyces sp. GS7 QHC26780.1    
 GR130_27985   Streptomyces sp. GS7 QHC24638.1    
 F9278_13735   Streptomyces sp. GY16 QFR02534.1    
 F9278_39830   Streptomyces sp. GY16 QFR03107.1    
 F9278_01125   Streptomyces sp. GY16 QFR02303.1    
 F9278_11675   Streptomyces sp. GY16 QFQ96773.1    
 GR129_29195   Streptomyces sp. HF10 QHC32265.1    
 GR129_11725   Streptomyces sp. HF10 QHC29393.1    
 G7Z12_06160   Streptomyces sp. ID38640 QIK11116.1    
 G7Z12_26585 (fragment)   Streptomyces sp. ID38640 QIK09057.1    
 G7Z12_26585 (fragment)   Streptomyces sp. ID38640 QIK09057.1    
 G7Z13_29225   Streptomyces sp. JB150 QIJ65651.1    
 D1J63_32895   Streptomyces sp. KPB2 AZM79219.1    
 CFP59_02439 (Neda_1)   Streptomyces sp. M56 AUA10340.1    
 CFP59_01742   Streptomyces sp. M56 AUA09652.1    
 CFP59_06452 (Neda_2)   Streptomyces sp. M56 AUA14274.1    
 EJ357_13195   Streptomyces sp. MK-45 AZQ34322.1    
 EJ357_15115   Streptomyces sp. MK-45 AZQ34644.1    
 EJ357_01525   Streptomyces sp. MK-45 AZQ32299.1    
 EJ357_39230   Streptomyces sp. MK-45 AZQ38742.1    
 STRMOE7_31410   Streptomyces sp. MOE7 ARH94053.1    
 STRMOE7_07000   Streptomyces sp. MOE7 ARH90086.1    
 DKG71_12975   Streptomyces sp. NEAU-S7GS2 AWN26925.1    
 DKG71_36330   Streptomyces sp. NEAU-S7GS2 AWN32487.1    
 DEH18_07610   Streptomyces sp. NHF165 QHF93755.1    
 DEH18_29595   Streptomyces sp. NHF165 QHF97303.1    
 F750_5720   Streptomyces sp. PAMC 26508 AGJ58149.1    
 QR97_03235   Streptomyces sp. PBH53 AKN68959.1    
 QR97_07950   Streptomyces sp. PBH53 AKN69768.1    
 QR97_13920   Streptomyces sp. PBH53 AKN70764.1    
 HA039_32980   Streptomyces sp. QMT-12 QIQ07308.1    
 GFH48_28685   Streptomyces sp. QMT-28 QFZ76706.1    
 GFH48_27215   Streptomyces sp. QMT-28 QFZ78967.1    
 GFH48_09325   Streptomyces sp. QMT-28 QFZ73431.1    
 FNV59_21225   Streptomyces sp. RLB1-8 QDO60332.1    
 FNV59_19430   Streptomyces sp. RLB1-8 QDO60028.1    
 FNV59_42780   Streptomyces sp. RLB1-8 QDO63946.1    
 FNV58_21865   Streptomyces sp. RLB1-9 QDN98310.1    
 FNV58_20050   Streptomyces sp. RLB1-9 QDN98009.1    
 FNV58_43795   Streptomyces sp. RLB1-9 QDO01967.1    
 FNV62_19285   Streptomyces sp. RLB3-17 QDO40030.1    
 FNV62_17500   Streptomyces sp. RLB3-17 QDO39733.1    
 FNV62_41900   Streptomyces sp. RLB3-17 QDO43783.1    
 FNV60_18985   Streptomyces sp. RLB3-5 QDO50092.1    
 FNV60_40530   Streptomyces sp. RLB3-5 QDO53701.1    
 FNV60_17185   Streptomyces sp. RLB3-5 QDO49787.1    
 FNV61_20200   Streptomyces sp. RLB3-6 QDN87642.1    
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