Glycoside Hydrolase Family 33

Activities in Familysialidase or neuraminidase (EC 3.2.1.18); trans-sialidase (EC 2.4.1.-); anhydrosialidase (EC 4.2.2.15); Kdo hydrolase (EC 3.2.1.-); 2-keto-3-deoxynononic acid hydrolase / KDNase (EC 3.2.1.-)
Mechanism Retaining
ClanGH-E
3D Structure Status6-fold β-propeller
Catalytic Nucleophile/BaseTyr+Glu
Catalytic Proton DonorNot known
External resourcesHOMSTRAD;
Commercial Enzyme Provider(s)MEGAZYME;
Statistics GenBank accession (6329); Uniprot accession (681); PDB accession (152); 3D entries (21); cryst (0)
All (6088) Archaea (1) Bacteria (5613) Eukaryota (431) Viruses (37) unclassified (6) Structure (21) Characterized (97)
| 1 | ... | 49 | 50 | 51 | 52 | 53 | 54 | 55 | 56 | 57 | ... | 58 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 FNV61_43535   Streptomyces sp. RLB3-6 QDN91475.1    
 FNV61_18290   Streptomyces sp. RLB3-6 QDN87328.1    
 FNV63_18510   Streptomyces sp. S1A1-3 QDO29841.1    
 FNV63_42405   Streptomyces sp. S1A1-3 QDO33825.1    
 FNV63_20325   Streptomyces sp. S1A1-3 QDO30143.1    
 FNV64_43915   Streptomyces sp. S1A1-7 QDN81578.1    
 FNV64_22245   Streptomyces sp. S1A1-7 QDN77966.1    
 FNV65_18495   Streptomyces sp. S1A1-8 QDO19716.1    
 FNV65_20310   Streptomyces sp. S1A1-8 QDO20018.1    
 FNV65_42380   Streptomyces sp. S1A1-8 QDO23699.1    
 FNV66_42050   Streptomyces sp. S1D4-14 QDN71246.1    
 FNV66_18935   Streptomyces sp. S1D4-14 QDN67378.1    
 FNV66_20730   Streptomyces sp. S1D4-14 QDN67679.1    
 FNV67_19340   Streptomyces sp. S1D4-20 QDN57203.1    
 FNV67_21535   Streptomyces sp. S1D4-20 QDN57582.1    
 FNV67_43200   Streptomyces sp. S1D4-20 QDN61192.1    
 FNV68_21285   Streptomyces sp. S1D4-23 QDO08463.1    
 FNV68_19390   Streptomyces sp. S1D4-23 QDO08142.1    
 FNV68_44620   Streptomyces sp. S1D4-23 QDO12300.1    
 D7Y56_26900   Streptomyces sp. S501 QBR09238.1    
 A8713_30840 (fragment)   Streptomyces sp. SAT1 ANH95025.1    
 CAG99_09570   Streptomyces sp. SCSIO 03032 ARQ69077.1    
 CAG99_09585   Streptomyces sp. SCSIO 03032 ARQ69080.1    
 CAG99_18855   Streptomyces sp. SCSIO 03032 ARQ70627.1    
 C1N79_30335   Streptomyces sp. SGAir0924 QCR50552.1    
 SACTE_5371   Streptomyces sp. SirexAA-E AEN13180.1    
 B9S66_01110   Streptomyces sp. SM17 AWL30851.1    
 B9S64_27555   Streptomyces sp. SM18 AWL41421.1    
 E5N77_30665   Streptomyces sp. SS52 QCB25691.1    
 GEV49_34235   Streptomyces sp. SYP-A7193 QFX85425.1    
 GEV49_06430   Streptomyces sp. SYP-A7193 QFX80593.1    
 GQF42_14315   Streptomyces sp. T44 QHA04305.1    
 GQF42_15675   Streptomyces sp. T44 QHA04535.1    
 EZV63_03360   Streptomyces sp. VN1 QIP69022.1    
 EZV63_31225   Streptomyces sp. VN1 QIP73745.1    
 D1J60_20090   Streptomyces sp. W1SF4 AZM90469.1    
 DMA15_32485   Streptomyces sp. WAC 01529 AZM56717.1    
 DMA15_10195   Streptomyces sp. WAC 01529 AZM52922.1    
 neuraminidase   Streptomyces sp. WAC 06738 AZM45985.1    
 DMB38_04650   Streptomyces sp. WAC 06738 AZM45212.1    
 C9F11_12665 (Neda1)   Streptomyces sp. YIM 121038 QCX76210.1    
 C9F11_32565 (Neda2)   Streptomyces sp. YIM 121038 QCX80099.1    
 D9753_24085   Streptomyces sp. Z022 AYN41452.1    
 D9753_25275   Streptomyces sp. Z022 AYN41637.1    
 D9753_05710   Streptomyces sp. Z022 AYN38499.1    
 DN051_25885   Streptomyces sp. ZFG47 AWW39669.1    
 DN051_27080   Streptomyces sp. ZFG47 AWW42671.1    
 DN051_09320   Streptomyces sp. ZFG47 AWW36806.1    
 CP982_33450   Streptomyces spectabilis ATCC 27465 QEV63009.1    
 CP982_13210   Streptomyces spectabilis ATCC 27465 QEV59573.1    
 FH965_32005   Streptomyces spectabilis NRRL 2792 QDQ14605.1    
 FH965_11985   Streptomyces spectabilis NRRL 2792 QDQ11215.1    
 SSPO_069900   Streptomyces sporoclivatus NBRC 100767 BBJ44272.1    
 SSPO_017880   Streptomyces sporoclivatus NBRC 100767 BBJ39070.1    
 neuraminidase   Streptomyces sporoclivatus NBRC 100767 BBJ40034.1    
 F3L20_13595   Streptomyces tendae 139 QER86798.1    
 GBW32_30290   Streptomyces tsukubensis AT3 QFR96538.1    
 DEJ45_33795   Streptomyces venezuelae ATCC 10595 QES16868.1    
 DEJ45_31555 (fragment)   Streptomyces venezuelae ATCC 10595 QES17633.1    
 SVEN_0307   Streptomyces venezuelae ATCC 10712 CCA53594.1
QER97200.1
   
 SVEN_0771 (fragment)   Streptomyces venezuelae ATCC 10712 CCA54058.1
QES03449.1
   
 DEJ47_10460   Streptomyces venezuelae ATCC 14583 QES26836.1    
 DEJ47_32330   Streptomyces venezuelae ATCC 14583 QES31919.1    
 DEJ48_05810   Streptomyces venezuelae ATCC 14584 QES32978.1    
 DEJ48_27920   Streptomyces venezuelae ATCC 14584 QES36716.1    
 DEJ49_31090   Streptomyces venezuelae ATCC 14585 QES44850.1    
 DEJ49_09950   Streptomyces venezuelae ATCC 14585 QES41290.1    
 DEJ46_36540   Streptomyces venezuelae ATCC 15068 QES23948.1    
 BN2537_15683   Streptomyces venezuelae ATCC 15439 CUM43359.1    
 AQF52_0784   Streptomyces venezuelae ATCC 15439 ALO06381.1    
 DEJ44_03605 (fragment)   Streptomyces venezuelae ATCC 21113 QES10455.1    
 DEJ44_01425   Streptomyces venezuelae ATCC 21113 QES04391.1    
 DEJ50_14070   Streptomyces venezuelae ATCC 21782 QES48778.1    
 neuraminidase   Streptomyces venezuelae ATCC 21782 QES50805.1    
 neuraminidase   Streptomyces venezuelae ATCC 21782 QES51956.1    
 B1H20_22730   Streptomyces violaceoruber S21 ARF66342.1    
 Strvi_2597   Streptomyces violaceusniger Tu 4113 AEM82314.1    
 Strvi_3597   Streptomyces violaceusniger Tu 4113 AEM83265.1    
 Strvi_7342   Streptomyces violaceusniger Tu 4113 AEM86701.1    
 CP969_30755   Streptomyces viridosporus T7A ATCC 39115 QEU88585.1    
 C1J05_12065   Sulfitobacter sp. JL08 AXI55131.1    
 KR49_09385   Synechococcus sp. KORDI-49 AII46653.1    
 TF3313_0675   Tannerella forsythia 3313 BAR48245.1    
 TF3313_2017   Tannerella forsythia 3313 BAR49484.1    
 BFO_0701   Tannerella forsythia 92A2 ATCC 43037 AEW20449.1    
 sialidase (NanH;TF0036;BFO_2207) 3.2.1.18 Tannerella forsythia 92A2 ATCC 43037 AEW22573.1    
 TFKS16_0644   Tannerella forsythia KS16 BAR50943.1    
 TFKS16_1972   Tannerella forsythia KS16 BAR52188.1    
 MARIT_2686 (SiaA)   Tenacibaculum maritimum SFZ84307.1    
 MARIT_2686 (SiaA)   Tenacibaculum maritimum SFZ84307.1    
 B9C57_11355   Tenacibaculum maritimum TM-KORJJ QCD63079.1    
 B9C57_11355   Tenacibaculum maritimum TM-KORJJ QCD63079.1    
 neuraminidase   Terriglobus albidus ORNL QEE31157.1    
 FTW19_21345   Terriglobus albidus ORNL QEE30300.1    
 FTW19_15115   Terriglobus albidus ORNL QEE29205.1    
 neuraminidase   Terriglobus roseus DSM 18391 AFL86731.1    
 Terro_1154   Terriglobus roseus DSM 18391 AFL87470.1    
 neuraminidase   Terriglobus roseus GAS232 SDF06571.1    
 neuraminidase   Terriglobus roseus GAS232 SDE92571.1    
 AciPR4_2821   Terriglobus saanensis SP1PR4 ADV83594.1 E1N2Z3  
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