Glycoside Hydrolase Family 33

Activities in Familysialidase or neuraminidase (EC 3.2.1.18); trans-sialidase (EC 2.4.1.-); anhydrosialidase (EC 4.2.2.15); Kdo hydrolase (EC 3.2.1.-); 2-keto-3-deoxynononic acid hydrolase / KDNase (EC 3.2.1.-)
Mechanism Retaining
ClanGH-E
3D Structure Status6-fold β-propeller
Catalytic Nucleophile/BaseTyr+Glu
Catalytic Proton DonorNot known
External resourcesHOMSTRAD;
Commercial Enzyme Provider(s)MEGAZYME;
Statistics GenBank accession (6329); Uniprot accession (681); PDB accession (152); 3D entries (21); cryst (0)
All (6088) Archaea (1) Bacteria (5613) Eukaryota (431) Viruses (37) unclassified (6) Structure (21) Characterized (97)
| 1 | ... | 44 | 45 | 46 | 47 | 48 | 49 | 50 | 51 | 52 | ... | 58 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 SAMEA3714262_01324 (Nanb_1)   Streptococcus pneumoniae 2245STDY6179186 VFI48247.1    
 SAMEA3714262_01324 (Nanb_1)   Streptococcus pneumoniae 2245STDY6179186 VFI48247.1    
 neuraminidase (Nana_3)   Streptococcus pneumoniae 2245STDY6179186 VFI48857.1    
 SAMEA3714262_01530 (Nanb_2)   Streptococcus pneumoniae 2245STDY6179186 VFI48840.1    
 SAMEA3714262_01530 (Nanb_2)   Streptococcus pneumoniae 2245STDY6179186 VFI48840.1    
 C4N11_06265   Streptococcus pneumoniae 335 AVD75144.1    
 C4N11_06265   Streptococcus pneumoniae 335 AVD75144.1    
 C4N11_08635   Streptococcus pneumoniae 335 AVD75579.1    
 C4N11_08635   Streptococcus pneumoniae 335 AVD75579.1    
 C4N11_08660   Streptococcus pneumoniae 335 AVD75584.1    
 neuraminidase (NanB)   Streptococcus pneumoniae 521 QBK28617.1    
 neuraminidase (NanB)   Streptococcus pneumoniae 521 QBK28617.1    
 sialidase A (NanA) 3.2.1.18 Streptococcus pneumoniae 6 CAA51473.1
ACJ76903.1
B8XTT3
P62575
Q59959
5KKY[A,B]
 sialidase B (NanB) 3.2.1.18 Streptococcus pneumoniae 6 AAC44396.1
AAW08718.1
Q54727  
 sialidase B (NanB) 3.2.1.18 Streptococcus pneumoniae 6 AAC44396.1 Q54727  
 SP670_0950   Streptococcus pneumoniae 670-6B ADM91015.1 E0TMG6  
 SP670_0950   Streptococcus pneumoniae 670-6B ADM91015.1 E0TMG6  
 SP670_1783   Streptococcus pneumoniae 670-6B ADM91835.1 E0TSF6  
 SP670_1773   Streptococcus pneumoniae 670-6B ADM91827.1 E0TSE8  
 neuraminidase   Streptococcus pneumoniae 70585 ACO17645.1    
 SP70585_1726   Streptococcus pneumoniae 70585 ACO17953.1 C1C8S5  
 SP70585_1726   Streptococcus pneumoniae 70585 ACO17953.1 C1C8S5  
 T308_07725   Streptococcus pneumoniae A026 AGZ48230.1    
 T308_07695   Streptococcus pneumoniae A026 AGZ48224.1    
 T308_07695   Streptococcus pneumoniae A026 AGZ48224.1    
 A66_01518   Streptococcus pneumoniae A66 CRI62229.1    
 A66_01513   Streptococcus pneumoniae A66 CRI62224.1    
 A66_01513   Streptococcus pneumoniae A66 CRI62224.1    
 neuraminidase (NanA)   Streptococcus pneumoniae A66.1 ACJ76912.1 B8XTU2  
 SPAP_1700   Streptococcus pneumoniae AP200 ADM85284.1 E0SWG1  
 SPAP_1354   Streptococcus pneumoniae AP200 ADM84940.1 E0SUC9  
 SPAP_1354   Streptococcus pneumoniae AP200 ADM84940.1 E0SUC9  
 SPAP_1692 (fragment)   Streptococcus pneumoniae AP200 ADM85276.1 E0SWF3  
 ASP0581_16330 (NanA)   Streptococcus pneumoniae ASP0581 BBG82155.1    
 ASP0581_12830 (NanB)   Streptococcus pneumoniae ASP0581 BBG81805.1    
 ASP0581_12830 (NanB)   Streptococcus pneumoniae ASP0581 BBG81805.1    
 SPAT_1555 (Nanb_2)   Streptococcus pneumoniae ATCC 49619 BBG39603.1    
 SPAT_1555 (Nanb_2)   Streptococcus pneumoniae ATCC 49619 BBG39603.1    
 SPAT_1561 (Nana_3)   Streptococcus pneumoniae ATCC 49619 BBG39609.1    
 SPAT_1230 (Nanb_1)   Streptococcus pneumoniae ATCC 49619 BBG39280.1    
 SPAT_1230 (Nanb_1)   Streptococcus pneumoniae ATCC 49619 BBG39280.1    
 neuraminidase   Streptococcus pneumoniae ATCC 700669 CAR69021.1 B8ZK40  
 neuraminidase   Streptococcus pneumoniae ATCC 700669 CAR69021.1 B8ZK40  
 neuraminidase (NanB)   Streptococcus pneumoniae ATCC 700669 CAR69459.1 B8ZMF2  
 neuraminidase (NanB)   Streptococcus pneumoniae ATCC 700669 CAR69459.1 B8ZMF2  
 neuraminidase (NanA)   Streptococcus pneumoniae ATCC 700669 CAR69464.1 B8ZMF7  
 neuraminidase (NanA)   Streptococcus pneumoniae AUSMDU00010538 QGK04319.1    
 neuraminidase (NanB)   Streptococcus pneumoniae AUSMDU00010538 QGK04314.1    
 neuraminidase (NanB)   Streptococcus pneumoniae AUSMDU00010538 QGK04314.1    
 NanA   Streptococcus pneumoniae BC7326 AMQ67148.1    
 NanA   Streptococcus pneumoniae CF6852 AMQ67142.1    
 NanA   Streptococcus pneumoniae CF6857 AMQ67143.1    
 NanA   Streptococcus pneumoniae CF6937 AMQ67144.1    
 sialidase (NanC;SPCG_0853) 3.2.1.18 Streptococcus pneumoniae CGSP14 ACB90105.1 B2IP34  
 sialidase (NanC;SPCG_0853) 3.2.1.18 Streptococcus pneumoniae CGSP14 ACB90105.1 B2IP34  
 SPCG_1660 (NanB)   Streptococcus pneumoniae CGSP14 ACB90912.1 B2IRU3  
 SPCG_1660 (NanB)   Streptococcus pneumoniae CGSP14 ACB90912.1 B2IRU3  
 SPCG_1665   Streptococcus pneumoniae CGSP14 ACB90917.1
ACJ76905.1
ACJ76908.1
ACJ76909.1
ACJ76932.1
B2IRU8  
 NanA   Streptococcus pneumoniae CJ9400 AMQ67146.1    
 neuraminidase (NanA) (fragment)   Streptococcus pneumoniae CL25 = 340 132217 CAI94554.1 Q4LB84  
 neuraminidase (NanA) (fragment)   Streptococcus pneumoniae CL37 = 162 GM123 CAI94567.1 Q4LB80  
 neuraminidase (NanA) (fragment)   Streptococcus pneumoniae Cl50 = 352- E/208 CAI94551.1
AIL27686.1
Q4LB89  
 neuraminidase (NanA) (fragment)   Streptococcus pneumoniae CL54 = 145 GM92 CAI94566.1 Q4LB86  
 neuraminidase (NanA) (fragment)   Streptococcus pneumoniae CL56 = 381 110K/70 CAI94568.1 Q4LB79  
 neuraminidase (NanA) (fragment)   Streptococcus pneumoniae CL57 = 398 CAI94571.1 Q4LB81  
 DA395_08290   Streptococcus pneumoniae CP2215 AVV91827.1    
 DA395_08290   Streptococcus pneumoniae CP2215 AVV91827.1    
 DA395_08315   Streptococcus pneumoniae CP2215 AVV91832.1    
 neuraminidase (NanA) (fragment)   Streptococcus pneumoniae CR13 = 884 141926 CAI94555.1 Q4LB83  
 neuraminidase (NanA) (fragment)   Streptococcus pneumoniae CR33 = 910 13B-15F CAI94565.1 Q4LB88  
 neuraminidase (NanA) (fragment)   Streptococcus pneumoniae CR50 = 967 12B-5L CAI94552.1 Q4LB87  
 neuraminidase (NanA) (fragment)   Streptococcus pneumoniae CR51 = 946 12B-21H CAI94556.1 Q4LB82  
 neuraminidase (NanA) (fragment)   Streptococcus pneumoniae CR8 = 956 12B-11F CAI94553.1 Q4LB85  
 SPND122_01617   Streptococcus pneumoniae D122 AOG56480.1    
 SPND122_01612   Streptococcus pneumoniae D122 AOG56475.1    
 SPND122_01612   Streptococcus pneumoniae D122 AOG56475.1    
 SPND141_01620   Streptococcus pneumoniae D141 AOG58634.1    
 SPND141_01620   Streptococcus pneumoniae D141 AOG58634.1    
 SPND141_01625   Streptococcus pneumoniae D141 AOG58639.1    
 SPND219_01714   Streptococcus pneumoniae D219 ANO37465.1    
 SPND219_01714   Streptococcus pneumoniae D219 ANO37465.1    
 SPND219_01719   Streptococcus pneumoniae D219 ANO37470.1    
 SPD_1499   Streptococcus pneumoniae D39 ABJ55283.1 Q04J83  
 SPD_1499   Streptococcus pneumoniae D39 ABJ55283.1 Q04J83  
 sialidase (NanA;SPD_1504) 3.2.1.18 Streptococcus pneumoniae D39 ABJ55437.1 Q04J78  
 SPV_1499 (NanB)   Streptococcus pneumoniae D39V AVN86574.1    
 SPV_1499 (NanB)   Streptococcus pneumoniae D39V AVN86574.1    
 SPV_1504 (NanA)   Streptococcus pneumoniae D39V AVN86579.1    
 C3Y86_07820   Streptococcus pneumoniae EF3030 AXK91899.1
QBF69421.1
   
 C3Y86_07820   Streptococcus pneumoniae EF3030 AXK91899.1
QBF69421.1
   
 C3Y86_07845   Streptococcus pneumoniae EF3030 AXK91904.1
QBF69426.1
   
 neuraminidase (NanA)   Streptococcus pneumoniae G54 ACF55470.1
ACJ76910.1
ACJ76928.1
B5E741  
 neuraminidase (NanB)   Streptococcus pneumoniae G54 ACF54964.1 B5E736  
 neuraminidase (NanB)   Streptococcus pneumoniae G54 ACF54964.1 B5E736  
 neuraminidase (NanC) 3.2.1.18 Streptococcus pneumoniae G54 ACF56230.1 B5E561 4YW0[A,B]
4YW1[A,B]
4YW2[A,B]
4YW3[A,B]
4YW4[A,B]
4YW5[A,B]
4YZ1[A,B]
4YZ2[A,B]
4YZ3[A,B]
4YZ4[A,B]
4YZ5[A,B]
5F9T[A,B]
 neuraminidase (NanC) 3.2.1.18 Streptococcus pneumoniae G54 ACF56230.1 B5E561 4YW0[A,B]
4YW1[A,B]
4YW2[A,B]
4YW3[A,B]
4YW4[A,B]
4YW5[A,B]
4YZ1[A,B]
4YZ2[A,B]
4YZ3[A,B]
4YZ4[A,B]
4YZ5[A,B]
5F9T[A,B]
 HMPREF1038_01669 (NanB)   Streptococcus pneumoniae gamPNI0373 AFS43693.1    
 HMPREF1038_01669 (NanB)   Streptococcus pneumoniae gamPNI0373 AFS43693.1    
 HMPREF1038_01674   Streptococcus pneumoniae gamPNI0373 AFS43698.1    
 neuraminidase (NanA)   Streptococcus pneumoniae H040400333 ACJ76913.1    
Top


Last update: 2020-04-01 © Copyright 1998-2020
AFMB - CNRS - Université d'Aix-Marseille