Glycoside Hydrolase Family 33

Activities in Familysialidase or neuraminidase (EC 3.2.1.18); trans-sialidase (EC 2.4.1.-); anhydrosialidase (EC 4.2.2.15); Kdo hydrolase (EC 3.2.1.-); 2-keto-3-deoxynononic acid hydrolase / KDNase (EC 3.2.1.-)
Mechanism Retaining
ClanGH-E
3D Structure Status6-fold β-propeller
Catalytic Nucleophile/BaseTyr+Glu
Catalytic Proton DonorNot known
External resourcesHOMSTRAD;
Commercial Enzyme Provider(s)MEGAZYME;
Statistics GenBank accession (6329); Uniprot accession (681); PDB accession (152); 3D entries (21); cryst (0)
All (6088) Archaea (1) Bacteria (5613) Eukaryota (431) Viruses (37) unclassified (6) Structure (21) Characterized (97)
| 1 | ... | 47 | 48 | 49 | 50 | 51 | 52 | 53 | 54 | 55 | ... | 58 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 BV401_14365   Streptomyces autolyticus CGMCC0516 AQA11494.1    
 BV401_38265   Streptomyces autolyticus CGMCC0516 AQA15388.1    
 BV401_34675   Streptomyces autolyticus CGMCC0516 AQA14795.1    
 SAV1842 (NanH)   Streptomyces avermitilis MA-4680 = NBRC 14893 BAC69553.1
NP_823018.1
   
 SAV5934   Streptomyces avermitilis MA-4680 = NBRC 14893 BAC73646.1
NP_827111.1
   
 SAV5606   Streptomyces avermitilis MA-4680 = NBRC 14893 BAC73318.1
NP_826783.1
   
 SAVMC3_64050   Streptomyces avermitilis MC3 BBJ53776.1    
 SAVMC3_67640   Streptomyces avermitilis MC3 BBJ54135.1    
 neuraminidase   Streptomyces avermitilis MC3 BBJ49565.1    
 SBI_02735   Streptomyces bingchenggensis BCW-1 ADI05856.1 D7C0Y4  
 SBI_07687   Streptomyces bingchenggensis BCW-1 ADI10807.1 D7CCW0  
 SBI_08925   Streptomyces bingchenggensis BCW-1 ADI12043.1 D7C003  
 CP983_07710   Streptomyces chartreusis ATCC 14922 QEV66568.1    
 CP983_29145   Streptomyces chartreusis ATCC 14922 QEV70306.1    
 CP983_30925   Streptomyces chartreusis ATCC 14922 QEV70620.1    
 CP983_41950   Streptomyces chartreusis ATCC 14922 QEV72566.1    
 SCO6557 or SC4B5.07c   Streptomyces coelicolor A3(2) CAA22361.1
NP_630638.1
Q9ZBW1  
 SCO0033 or SCJ4.14c   Streptomyces coelicolor A3(2) CAB52948.1
NP_624391.1
Q9S1V9  
 FQ762_00155   Streptomyces coelicolor A3(2) CFB_NBC_0001 QFI40368.1    
 FQ762_33840   Streptomyces coelicolor A3(2) CFB_NBC_0001 QFI46352.1    
 CP976_36110   Streptomyces coeruleorubidus ATCC 13740 QEV29010.1    
 CP976_13000   Streptomyces coeruleorubidus ATCC 13740 QEV24999.1    
 B446_11895   Streptomyces collinus Tu 365 AGS69201.1    
 B446_13015   Streptomyces collinus Tu 365 AGS69421.1    
 neuraminidase   Streptomyces collinus Tu 365 AGS72834.1    
 TU94_27930   Streptomyces cyaneogriseus subsp. noncyanogenus NMWT 1 AJP04710.1    
 BN159_5780   Streptomyces davaonensis JCM 4913 CCK30159.1    
 BN159_6167   Streptomyces davaonensis JCM 4913 CCK30546.1    
 BN159_5931 (fragment)   Streptomyces davaonensis JCM 4913 CCK30310.1    
 C4B68_28920   Streptomyces dengpaensis XZHG99 AVH59102.1    
 C4B68_27200   Streptomyces dengpaensis XZHG99 AVH58839.1    
 C4B68_06220   Streptomyces dengpaensis XZHG99 AVH55440.1    
 KY5_6912c   Streptomyces formicae KY5 ATL31930.1    
 KY5_2262c   Streptomyces formicae KY5 ATL27280.1    
 D3X13_04990   Streptomyces fradiae NKZ-259 AYA15672.1    
 D3X13_24790   Streptomyces fradiae NKZ-259 AYA19028.1    
 SFUL_4680   Streptomyces fulvissimus DSM 40593 AGK79576.1    
 CNQ36_27065   Streptomyces fungicidicus TXX3120 AYL38740.1    
 B1H19_08245   Streptomyces gilvosporeus F607 ARF59300.1    
 B1H19_32765   Streptomyces gilvosporeus F607 ARF58324.1    
 B1H19_13200   Streptomyces gilvosporeus F607 ARF59408.1    
 AVL59_14305   Streptomyces griseochromogenes ATCC 14511 ANP50638.1    
 AVL59_39820   Streptomyces griseochromogenes ATCC 14511 ANP54925.1    
 AVL59_38345   Streptomyces griseochromogenes ATCC 14511 ANP54677.1    
 ELQ87_26735   Streptomyces griseoviridis F1-27 AZS87422.1    
 SGR_6429   Streptomyces griseus subsp. griseus NBRC 13350 BAG23258.1 B1W5V1  
 CEB94_34630   Streptomyces hawaiiensis ATCC 12236 QCD59365.1    
 SHJG_3753   Streptomyces hygroscopicus subsp. jinggangensis 5008 AEY89025.1    
 SHJG_4013   Streptomyces hygroscopicus subsp. jinggangensis 5008 AEY89285.1    
 neuraminidase   Streptomyces hygroscopicus subsp. jinggangensis 5008 AEY92776.1    
 neuraminidase   Streptomyces hygroscopicus subsp. jinggangensis TL01 AGF66932.1    
 SHJGH_3778   Streptomyces hygroscopicus subsp. jinggangensis TL01 AGF63443.1    
 SHJGH_3518   Streptomyces hygroscopicus subsp. jinggangensis TL01 AGF63183.1    
 SHL15_2558   Streptomyces hygroscopicus subsp. limoneus KCTC 1717 ALO93707.1    
 SHL15_2303   Streptomyces hygroscopicus subsp. limoneus KCTC 1717 ALO93459.1    
 SHXM_01605   Streptomyces hygroscopicus XM201 AQW48142.1    
 SHXM_02791   Streptomyces hygroscopicus XM201 AQW49328.1    
 SHXM_03802   Streptomyces hygroscopicus XM201 AQW50339.1    
 ABB07_27015 (fragment)   Streptomyces incarnatus NRRL 8089 AKJ13550.1    
 ABB07_06030   Streptomyces incarnatus NRRL 8089 AKJ09590.1    
 ABB07_25670   Streptomyces incarnatus NRRL 8089 AKJ13297.1    
 SIRAN7080   Streptomyces iranensis CDR10828.1    
 SIRAN1596   Streptomyces iranensis CDR04302.1    
 SIRAN2508   Streptomyces iranensis CDR05563.1    
 CP970_31165   Streptomyces kanamyceticus ATCC 12853 QEU94756.1    
 CP970_05540   Streptomyces kanamyceticus ATCC 12853 QEU90446.1    
 D0C37_30975   Streptomyces koyangensis VK-A60T AXQ58598.1    
 SLAV_16675 (Neda1)   Streptomyces lavendulae subsp. lavendulae CCM 3239 ATZ25185.1    
 Sle_12050   Streptomyces leeuwenhoekii C34 (= DSM 42122 = NRRL B-24963) CQR60667.1    
 neuraminidase   Streptomyces lincolnensis LC-G AXG58119.1    
 SLCG_6964   Streptomyces lincolnensis LC-G AXG58119.1    
 SLCG_5499   Streptomyces lincolnensis LC-G AXG56654.1    
 SLCG_5499   Streptomyces lincolnensis LC-G AXG56654.1    
 neuraminidase   Streptomyces lincolnensis NRRL 2936 ANS69200.1    
 SLINC_2914   Streptomyces lincolnensis NRRL 2936 ANS65138.1    
 SLIV_05645   Streptomyces lividans TK24 AIJ12144.1    
 EKH77_26215   Streptomyces luteoverticillatus CGMCC 15060 AZQ74247.1    
 SL103_24060   Streptomyces lydicus 103 AOP48908.1    
 SL103_13095   Streptomyces lydicus 103 AOP47065.1    
 SL103_07905 (fragment)   Streptomyces lydicus 103 AOP46171.1    
 DDE74_33435   Streptomyces lydicus WYEC 108 AZS76819.1    
 neuraminidase   Streptomyces malaysiensis DSM 4137 ATL86407.1
QDL70019.1
   
 SMALA_6927   Streptomyces malaysiensis DSM 4137 ATL87147.1
QDL69382.1
   
 DNK48_32465   Streptomyces malaysiensis DSM 4137 QDL73269.1
ATL82417.1
   
 CP967_05270   Streptomyces nitrosporeus ATCC 12769 QEU71446.1    
 BBN63_34045   Streptomyces niveus SCSIO 3406 AQU70446.1    
 BBN63_01630   Streptomyces niveus SCSIO 3406 AQU65158.1    
 CP978_11820   Streptomyces nodosus ATCC 14899 QEV39160.1    
 SNOD_11480   Streptomyces nodosus ATCC 14899 AJE40603.1    
 neuraminidase   Streptomyces noursei ATCC 11455 ANZ15411.1    
 BC342_02930   Streptomyces pactum KLBMP 5084 AOW85646.1    
 Spa2297_27290   Streptomyces parvulus 2297 ANJ10358.1    
 CP981_31935   Streptomyces platensis ATCC 23948 QEV55621.1    
 LK06_009320 (fragment)   Streptomyces pluripotens MUSC 135 ARP70133.1    
 LK07_10435 (fragment)   Streptomyces pluripotens MUSC 137 ASN24392.1    
 CP972_29505   Streptomyces prasinus ATCC 13879 QEV09199.1    
 CP972_31580   Streptomyces prasinus ATCC 13879 QEV09540.1    
 Sfla_1120   Streptomyces pratensis ATCC 33331 ADW02574.1 C9NF48  
 SPRI_6322   Streptomyces pristinaespiralis HCCB 10218 ALC24628.1    
 BFF78_29875   Streptomyces puniciscabiei TW1S1 AOR34698.1    
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