Carbohydrate-Binding Module Family 50

Known ActivitiesModules of approx. 50 residues found attached to various enzymes from families GH18, GH19, GH23, GH24, GH25 and GH73, i.e. enzymes cleaving either chitin or peptidoglycan. Binding to chitopentaose demonstrated in the case of Pteris ryukyuensis chitinase A [Ohnuma T et al. (2008) J. Biol. Chem. 283:5178-87 (PMID: 18083709)]. CBM50 modules are also found in a multitude of other enzymes targeting the petidoglycan such as peptidases and amidases. These enzymes are not reported in the list below.
NoteAlso known as LysM domains
External resourcesInterPro; PFAM;
Statistics GenBank accession (3148); Uniprot accession (1452); PDB accession (2); 3D entries (3); cryst (1)
All (5085) Archaea (3) Bacteria (4849) Eukaryota (149) Viruses (80) unclassified (4) Structure (3 - 1 cryst) Characterized (2)
Viruses
Protein Name EC#OrganismGenBankUniprotPDB/3D
 endolysin   Bacillus amyloliquefaciens phage Morita2001 AAK40280.1 Q94ML9  
 endolysin   Bacillus amyloliquefaciens phage Morita2001 AAK40280.1 Q94ML9  
 lysozyme (B103_15)   Bacillus phage B103 CAA67646.1
NP_690649.1
Q37896  
 lysozyme (B103_15)   Bacillus phage B103 CAA67646.1
NP_690649.1
Q37896  
 G_22 (22)   Bacillus phage G AEO93293.1    
 G_185 (185)   Bacillus phage G AEO93445.1    
 G_185 (185)   Bacillus phage G AEO93445.1    
 G_185 (185)   Bacillus phage G AEO93445.1    
 G_23 (23)   Bacillus phage G AEO93294.1    
 peptidoglycan hydrolase (15)   Bacillus phage Nf ACH57083.1 B7SSN6  
 peptidoglycan hydrolase (15)   Bacillus phage Nf ACH57083.1 B7SSN6  
 phi105_26 / PHI105_00120   Bacillus phage phi105 ADF59157.1
BAA36652.1
NP_690779.1
Q9ZXD7  
 lysozyme   Bacillus phage phi29 AAA32288.1
AAA88347.1
ACE96038.1
CAA28632.1
B3VMQ1
P11187.1
 
 lysozyme   Bacillus phage phi29 AAA32288.1
AAA88347.1
ACE96038.1
CAA28632.1
B3VMQ1
P11187.1
 
 lysozyme   Bacillus phage PZA AAA88492.1 P07540.1  
 lysozyme   Bacillus phage PZA AAA88492.1 P07540.1  
 PHIEF11_0026   Enterococcus phage phiEf11 ACV83340.1 C9E2L1  
 PHIEF11_0026   Enterococcus phage phiEf11 ACV83340.1 C9E2L1  
 endolysin (Gp60)   Enterococcus phage phiFL1A ACZ63759.1 D2IYY2  
 endolysin (Gp60)   Enterococcus phage phiFL1A ACZ63759.1 D2IYY2  
 endolysin (Gp62)   Enterococcus phage phiFL1B ACZ63822.1 D2IZ45  
 endolysin (Gp62)   Enterococcus phage phiFL1B ACZ63822.1 D2IZ45  
 endolysin (Gp72)   Enterococcus phage phiFL1C ACZ63895.1 D2IZB8  
 endolysin (Gp72)   Enterococcus phage phiFL1C ACZ63895.1 D2IZB8  
 endolysin (Gp61)   Enterococcus phage phiFL2A ACZ63958.1 D2IZI1  
 endolysin (Gp61)   Enterococcus phage phiFL2A ACZ63958.1 D2IZI1  
 endolysin (Gp58)   Enterococcus phage phiFL2B ACZ64018.1 D2IZP1  
 endolysin (Gp58)   Enterococcus phage phiFL2B ACZ64018.1 D2IZP1  
 endolysin (Gp63)   Enterococcus phage phiFL3A ACZ64082.1 D2IZV5  
 endolysin (Gp63)   Enterococcus phage phiFL3A ACZ64082.1 D2IZV5  
 endolysin (Gp65)   Enterococcus phage phiFL3B ACZ64148.1 D2J021  
 endolysin (Gp65)   Enterococcus phage phiFL3B ACZ64148.1 D2J021  
 endolysin (Gp55)   Enterococcus phage phiFL4A ACZ64204.1 D2J077  
 endolysin (Gp55)   Enterococcus phage phiFL4A ACZ64204.1 D2J077  
 ORF399   Lactobacillus phage JCL1032 AAQ75056.1
AAQ75056.2
A9UJV4  
 lb338_phage_127   Lactobacillus phage Lb338-1 ACO37048.1 C1KFN7  
 lb338_phage_127   Lactobacillus phage Lb338-1 ACO37048.1 C1KFN7  
 lb338_phage_127   Lactobacillus phage Lb338-1 ACO37048.1 C1KFN7  
 ORF432   Lactobacillus phage Lc-Nu AAR04645.1 A8YQK7  
 ORF432   Lactobacillus phage Lc-Nu AAR04645.1 A8YQK7  
 lysin   Lactobacillus phage LF1 ADW01249.1    
 lysin   Lactobacillus phage LF1 ADW01249.1    
 lysin   Lactobacillus phage LF1 ADW01249.1    
 lysin   Lactobacillus phage Lrm1 M-1 ABY84320.1 B4XYQ9  
 lysin   Lactobacillus phage Lrm1 M-1 ABY84320.1 B4XYQ9  
 Lys   Lactobacillus phage phig1e CAA62097.1 O03950  
 endolysin (Lyb5)   Lactobacillus phage phiPYB5 ABP88927.1 A5A5E0  
 endolysin (Lyb5)   Lactobacillus phage phiPYB5 ABP88927.1 A5A5E0  
 endolysin (Lyb5)   Lactobacillus phage phiPYB5 ABP88927.1 A5A5E0  
 endolysin   Lactobacillus phage Sha1 ADW01314.1    
 ORF   Lactococcus phage 949 ADM73688.1 E0YJ17  
 ORF50   Lactococcus phage P335 ABI54253.1 B5SP49  
 ORF50   Lactococcus phage P335 ABI54253.1 B5SP49  
 endolysin   Lactococcus phage phiAM2 AAG24366.1 Q9FZS8  
 endolysin   Lactococcus phage phiAM2 AAG24366.1 Q9FZS8  
 LysB   Lactococcus phage phiLC3 IMN-C3 AAA20878.1 Q37969  
 LysB   Lactococcus phage phiLC3 IMN-C3 AAA20878.1 Q37969  
 lysin (Lys)   Lactococcus phage TP901-1 AAK38070.1
NP_112716.1
Q9AZ52  
 lysin (Lys)   Lactococcus phage TP901-1 AAK38070.1
NP_112716.1
Q9AZ52  
 LYS   Lactococcus phage Tphi712 AAX13240.1    
 LYS   Lactococcus phage Tphi712 AAX13240.1    
 lysin   Lactococcus phage TPW22 AAF12705.1 Q9T1Z3  
 lysin   Lactococcus phage TPW22 AAF12705.1 Q9T1Z3  
 lysin   Lactococcus phage Tuc2009 AAK19881.1
NP_108734.1
Q38614  
 lysin   Lactococcus phage Tuc2009 AAK19881.1
NP_108734.1
Q38614  
 lysin   Lactococcus phage ul36 AAM75805.1
NP_663692.1
Q8LTP4  
 lysin   Lactococcus phage ul36 AAM75805.1
NP_663692.1
Q8LTP4  
 lysin   Lactococcus phage ul36.k1 ABD63694.1 A5GYG5  
 lysin   Lactococcus phage ul36.k1 ABD63694.1 A5GYG5  
 endolysin   Lactococcus phage ul36.k1t1 ABD63745.1 A5GYL4  
 endolysin   Lactococcus phage ul36.k1t1 ABD63745.1 A5GYL4  
 gp26   Listeria phage P40 ACI00386.1 B6D7J9  
 ORF432   Oenoccocus phage fOgPSU1 CAF32661.1 Q6EVN0  
 ORF432   Oenoccocus phage fOgPSU1 CAF32661.1 Q6EVN0  
 ORF432   Oenococcus phage fOg30 CAF32671.1 Q6A204  
 ORF432   Oenococcus phage fOg30 CAF32671.1 Q6A204  
 Lys44   Oenococcus phage fOg44 AAD10705.1
AAD10705.2
CAD19148.1
Q9ZXH8  
 Lys44   Oenococcus phage fOg44 AAD10705.1
AAD10705.2
CAD19148.1
Q9ZXH8  
 lysin   Rhodococcus phage REQ1 AEV52059.1    
 Vi01_110c   Salmonella phage Vi01 CBW37978.1 E1XTB9  




Last update: 2012-01-31 © Copyright 1998-2012
AFMB - CNRS - Universités Aix-Marseille I & II