Carbohydrate-Binding Module Family 50

Activities in FamilyModules of approx. 50 residues found attached to various enzymes from families GH18, GH19, GH23, GH24, GH25 and GH73, i.e. enzymes cleaving either chitin or peptidoglycan. Binding to chitopentaose demonstrated in the case of Pteris ryukyuensis chitinase A [Ohnuma T et al. (2008) J. Biol. Chem. 283:5178-87 (PMID: 18083709)]. CBM50 modules are also found in a multitude of other enzymes targeting the petidoglycan such as peptidases and amidases. These enzymes are not reported in the list below.
NoteAlso known as LysM domains
External resourcesCAZypedia;
Statistics GenBank accession (32450); Uniprot accession (1529); PDB accession (27); 3D entries (18); cryst (0)
All (46550) Archaea (12) Bacteria (45699) Eukaryota (444) Viruses (387) unclassified (8) Structure (18) Characterized (52)
| 1 | 2 | 3 | 4 |
Viruses
Protein Name EC#OrganismGenBank UniprotPDB/3D
 endolysin   Geobacillus phage TP-84 AQY55126.1    
 endolysin   Geobacillus phage TP-84 AQY55126.1    
 endolysin   Geobacillus phage TP-84 AQY55126.1    
 endolysin   Geobacillus phage TP-84 AQY55126.1    
 endolysin   Geobacillus phage TP-84 AQY55126.1    
 endolysin   Geobacillus phage TP-84 AQY55126.1    
 KP27_024   Klebsiella phage KP27 AEX26500.1    
 CPT_Matisse18   Klebsiella phage Matisse AKU44322.1    
 CPT_Miro18   Klebsiella phage Miro AKU44602.1    
 Phage protein   Klebsiella phage PMBT1 SCO64595.1    
 8014-B2_0040   Lactobacillus phage ATCC 8014-B2 AFU63107.1    
 8014-B2_0057   Lactobacillus phage ATCC 8014-B2 AFU63124.1    
 BN20_022 (Ev3_022)   Lactobacillus phage EV3 CUQ99445.1    
 BN20_022 (Ev3_022)   Lactobacillus phage EV3 CUQ99445.1    
 iLp84_23   Lactobacillus phage iLp84 ALJ97855.1    
 ORF399   Lactobacillus phage JCL1032 AAQ75056.1
AAQ75056.2
A9UJV4  
 ORF432   Lactobacillus phage Lc-Nu AAR04645.1 A8YQK7  
 ORF432   Lactobacillus phage Lc-Nu AAR04645.1 A8YQK7  
 LDL_034   Lactobacillus phage Ldl1 AIS73892.1    
 LDL_042   Lactobacillus phage Ldl1 AIS73900.1    
 lysin   Lactobacillus phage LF1 ADW01249.1    
 lysin   Lactobacillus phage LF1 ADW01249.1    
 lysin   Lactobacillus phage LF1 ADW01249.1    
 LfeInf_051   Lactobacillus phage LfeInf AIZ94677.1    
 LfeInf_051   Lactobacillus phage LfeInf AIZ94677.1    
 LfeInf_051   Lactobacillus phage LfeInf AIZ94677.1    
 LfeInf_051   Lactobacillus phage LfeInf AIZ94677.1    
 LfeInf_045   Lactobacillus phage LfeInf AIZ94671.1    
 lysin   Lactobacillus phage Lrm1 M-1 ABY84320.1 B4XYQ9  
 lysin   Lactobacillus phage Lrm1 M-1 ABY84320.1 B4XYQ9  
 LVP1_g022   Lactobacillus phage P1 ANO57951.1    
 LVP1_g034   Lactobacillus phage P1 ANO57963.1    
 Lys   Lactobacillus phage phig1e CAA62097.1 O03950  
 endolysin (Lyb5) 3.2.1.17 Lactobacillus phage phiPYB5 ABP88927.1 A5A5E0  
 endolysin (Lyb5) 3.2.1.17 Lactobacillus phage phiPYB5 ABP88927.1 A5A5E0  
 endolysin (Lyb5) 3.2.1.17 Lactobacillus phage phiPYB5 ABP88927.1 A5A5E0  
 PLE3_23   Lactobacillus phage PLE3 ANJ65422.1    
 SAC12_006   Lactobacillus phage SA-C12 ALY06828.1    
 SAC12_111   Lactobacillus phage SA-C12 ALY06932.1    
 endolysin   Lactobacillus phage Sha1 ADW01314.1    
 lb338_phage_127   Lactobacillus virus Lb338-1 ACO37048.1 C1KFN7  
 lb338_phage_127   Lactobacillus virus Lb338-1 ACO37048.1 C1KFN7  
 lb338_phage_127   Lactobacillus virus Lb338-1 ACO37048.1 C1KFN7  
 DS50101_49   Lactococcus phage 50101 ANS02441.1    
 DS50101_49   Lactococcus phage 50101 ANS02441.1    
 DS50902_47   Lactococcus phage 50902 ANT43437.1    
 DS50902_47   Lactococcus phage 50902 ANT43437.1    
 DS53802_58   Lactococcus phage 53802 ANT43548.1    
 DS53802_58   Lactococcus phage 53802 ANT43548.1    
 DS58502_49   Lactococcus phage 58502 ANT43596.1    
 DS58502_49   Lactococcus phage 58502 ANT43596.1    
 DS62502_52   Lactococcus phage 62502 ANT43648.1    
 DS62502_52   Lactococcus phage 62502 ANT43648.1    
 DS62503_50   Lactococcus phage 62503 ANT43698.1    
 DS62503_50   Lactococcus phage 62503 ANT43698.1    
 DS63301_48   Lactococcus phage 63301 ANS02645.1    
 DS63301_48   Lactococcus phage 63301 ANS02645.1    
 DS86501_50   Lactococcus phage 86501 ANS02695.1    
 DS86501_50   Lactococcus phage 86501 ANS02695.1    
 ORF   Lactococcus phage 949 ADM73688.1 E0YJ17  
 AM1_004   Lactococcus phage AM1 ARM66131.1    
 AM1_154   Lactococcus phage AM1 ARM66281.1    
 AM11_154   Lactococcus phage AM11 ARM67546.1    
 AM11_004   Lactococcus phage AM11 ARM67396.1    
 AM12_004   Lactococcus phage AM12 ARQ95583.1    
 AM12_154   Lactococcus phage AM12 ARQ95733.1    
 AM2_004   Lactococcus phage AM2 ARM66309.1    
 AM2_153   Lactococcus phage AM2 ARM66458.1    
 AM3_153   Lactococcus phage AM3 ARM66635.1    
 AM3_004   Lactococcus phage AM3 ARM66486.1    
 AM4_004   Lactococcus phage AM4 ARM66663.1    
 AM4_119   Lactococcus phage AM4 ARM66778.1    
 AM5_158   Lactococcus phage AM5 ARM67011.1    
 AM5_004   Lactococcus phage AM5 ARM66857.1    
 AM8_154   Lactococcus phage AM8 ARM67189.1    
 AM8_004   Lactococcus phage AM8 ARM67039.1    
 AM9_154   Lactococcus phage AM9 ARM67367.1    
 AM9_004   Lactococcus phage AM9 ARM67217.1    
 BM13_54   Lactococcus phage BM13 AFR52646.1    
 BM13_54   Lactococcus phage BM13 AFR52646.1    
 LW81_004   Lactococcus phage LW81 ARM67574.1    
 LW81_154   Lactococcus phage LW81 ARM67724.1    
 ORF50   Lactococcus phage P335 ABI54253.1 B5SP49  
 ORF50   Lactococcus phage P335 ABI54253.1 B5SP49  
 endolysin   Lactococcus phage phiAM2 AAG24366.1 Q9FZS8  
 endolysin   Lactococcus phage phiAM2 AAG24366.1 Q9FZS8  
 T548_0166   Lactococcus phage phiL47 AHC94243.1    
 LysB   Lactococcus phage phiLC3 IMN-C3 AAA20878.1 Q37969  
 LysB   Lactococcus phage phiLC3 IMN-C3 AAA20878.1 Q37969  
 ORF   Lactococcus phage PLg-TB25 APC44676.1    
 ORF   Lactococcus phage PLg-TB25 APC44676.1    
 LYS   Lactococcus phage TP712 AAX13240.1    
 LYS   Lactococcus phage TP712 AAX13240.1    
 lysin (Lys)   Lactococcus phage TP901-1 AAK38070.1
NP_112716.1
Q9AZ52  
 lysin (Lys)   Lactococcus phage TP901-1 AAK38070.1
NP_112716.1
Q9AZ52  
 lysin   Lactococcus phage TPW22 AAF12705.1 Q9T1Z3  
 lysin   Lactococcus phage TPW22 AAF12705.1 Q9T1Z3  
 lysin   Lactococcus phage Tuc2009 AAK19881.1
NP_108734.1
Q38614  
 lysin   Lactococcus phage Tuc2009 AAK19881.1
NP_108734.1
Q38614  
 lysin   Lactococcus phage ul36 AAM75805.1
NP_663692.1
Q8LTP4  
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