Carbohydrate-Binding Module Family 50

Activities in FamilyModules of approx. 50 residues found attached to various enzymes from families GH18, GH19, GH23, GH24, GH25 and GH73, i.e. enzymes cleaving either chitin or peptidoglycan. Binding to chitopentaose demonstrated in the case of Pteris ryukyuensis chitinase A [Ohnuma T et al. (2008) J. Biol. Chem. 283:5178-87 (PMID: 18083709)]. CBM50 modules are also found in a multitude of other enzymes targeting the petidoglycan such as peptidases and amidases. These enzymes are not reported in the list below.
NoteAlso known as LysM domains
External resourcesCAZypedia;
Statistics GenBank accession (122948); Uniprot accession (16); PDB accession (42); 3D entries (29); cryst (0)
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Viruses
Protein Name EC#OrganismGenBank UniprotPDB/3D
 LIKA_26   Streptomyces phage Lika AGM12049.1    
 SEA_LILMARTIN_41   Streptomyces phage LilMartin QNN98291.1    
 SEA_LIMPID_21   Streptomyces phage Limpid QGH79354.1    
 SEA_LORELEI_26   Streptomyces phage Lorelei AOQ26925.1    
 SEA_LUCKYSOCKE_185   Streptomyces phage LuckySocke WPH58883.1    
 SEA_LUCKYSOCKE_182   Streptomyces phage LuckySocke WPH58886.1    
 SEA_LUKECAGE_45   Streptomyces phage LukeCage AXH69571.1    
 SEA_MANEEKUL_25   Streptomyces phage Maneekul AWN07394.1    
 SEA_MEGANTHEEKILLA_23   Streptomyces phage MeganTheeKilla QQV92392.1    
 SEA_MILDRED21_42   Streptomyces phage Mildred21 ASR75449.1    
 SEA_MULCHMANSION_41   Streptomyces phage MulchMansion QNO12465.1    
 SEA_MUNTAHA_17   Streptomyces phage Muntaha QIN94574.1    
 SEA_NABI_26   Streptomyces phage Nabi AWN07320.1    
 SEA_NANODON_28   Streptomyces phage Nanodon ANT41098.1    
 SEA_NERDOS_26   Streptomyces phage Nerdos QAY17844.1    
 SEA_NOOTNOOT_40   Streptomyces phage NootNoot ASR77309.1    
 SEA_OLIYNYK_27   Streptomyces phage Oliynyk ATE85357.1    
 SEA_OZZIE_26   Streptomyces phage Ozzie ATE85431.1    
 SEA_OZZYJ_26   Streptomyces phage OzzyJ AVE00407.1    
 SEA_PARADIDDLES_40   Streptomyces phage Paradiddles ASR77530.1    
 SEA_PEEBS_43   Streptomyces phage Peebs ASR77749.1    
 SEA_PERSIMMON_39   Streptomyces phage Persimmon WNM72921.1    
 SEA_PHETTUCCINE_26   Streptomyces phage Phettuccine QGJ91543.1    
 endolysin   Streptomyces phage phiScoe15 WJN62725.1    
 endolysin   Streptomyces phage phiScoe23 WJN62882.1    
 SEA_PHREDRICK_23   Streptomyces phage Phredrick WNN94611.1    
 SEA_PINKIEPIE_42   Streptomyces phage PinkiePie WNM74705.1    
 SEA_RANA_26   Streptomyces phage Rana AWN07244.1    
 SEA_REDBEAR_27   Streptomyces phage RedBear QYW07873.1    
 SEA_RUSTICUS_27   Streptomyces phage Rusticus QDK03958.1    
 SEA_SAMISTI12_44   Streptomyces phage Samisti12 AST15275.1    
 SEA_SARAHROSE_25   Streptomyces phage SarahRose QZE11093.1    
 SEA_SATIS_118   Streptomyces phage Satis AXH66279.1    
 SF1_420   Streptomyces phage SF1 AKY02191.1    
 SF3_220   Streptomyces phage SF3 ALF00153.1    
 CPT_Shady_040   Streptomyces phage Shady QPB09801.1    
 CPT_Shaeky_040   Streptomyces phage Shaeky QPB09727.1    
 SEA_SHAM_19   Streptomyces phage Sham UUG69355.1    
 SEA_SNORLAX_25   Streptomyces phage Snorlax UKH48527.1    
 SEA_SOJO_22   Streptomyces phage SoJo WIC89740.1    
 SEA_SOLLERTIA_46   Streptomyces phage Sollertia WNM73634.1    
 SEA_SOUTH40_26   Streptomyces phage South40 QZE11022.1    
 SEA_SPARKLEGODDESS_22   Streptomyces phage SparkleGoddess AXH68737.1    
 SEA_SQUILLIUM_43   Streptomyces phage Squillium UOW93475.1    
 SEA_STANIMAL_46   Streptomyces phage Stanimal UVD39893.1    
 SEA_STARPLATINUM_45   Streptomyces phage StarPlatinum AXH66793.1    
 SEA_STIGMA_22   Streptomyces phage Stigma UTN92278.1    
 SUJIDADE_27   Streptomyces phage Sujidade AGM12125.1    
 SEA_SUNSETPOINTE_26   Streptomyces phage SunsetPointe UJQ86444.1    
 SEA_SUSHI23_44   Streptomyces phage Sushi23 ASR76476.1    
 CPT_Sycamore_039   Streptomyces phage Sycamore QPB09579.1    
 SEA_TAGEPHIGHTER_26   Streptomyces phage TagePhighter WAB09807.1    
 SEA_TARGARYEN_45   Streptomyces phage Targaryen UEM46833.1    
 SEA_TEUTSCH_44   Streptomyces phage Teutsch QAX95780.1    
 SEA_TOMA_26   Streptomyces phage Toma AWN07621.1    
 SEA_TOMAS_47   Streptomyces phage Tomas UMO76236.1    
 SEA_TRIBUTE_42   Streptomyces phage Tribute QGH78234.1    
 SEA_TRISTE_25   Streptomyces phage Triste QYW07944.1    
 SEA_TUANPN_25   Streptomyces phage TuanPN QDK03196.1    
 SEA_TUNATARTARE_20   Streptomyces phage TunaTartare QWT29913.1    
 SEA_TURKISHDELIGHT_35   Streptomyces phage TurkishDelight QPL14064.1    
 SEA_UNSTOPPABLE_26   Streptomyces phage Unstoppable UJQ86646.1    
 SEA_VERSE_27   Streptomyces phage Verse AKY03857.1    
 SEA_VIEENROSE_28   Streptomyces phage VieEnRose USH45863.1    
 SEA_WAKANDA_17   Streptomyces phage Wakanda QIN94010.1    
 SEA_WARPY_48   Streptomyces phage Warpy ASN73122.1    
 SEA_WATERMOORE_44   Streptomyces phage Watermoore WNN95405.1    
 SEA_WERNER_25   Streptomyces phage Werner QQV92846.1    
 SEA_WHATEVER_25   Streptomyces phage Whatever QFP95192.1    
 SEA_WOFFORD_44   Streptomyces phage Wollford AXH67240.1    
 SEA_YABOI_46   Streptomyces phage Yaboi AYB70884.1    
 SEA_YASDNIL_25   Streptomyces phage Yasdnil QDK03750.1    
 ZEMYLA_27   Streptomyces phage Zemlya AGM12202.1    
 PBI_PBS1_205   Takahashivirus PBS1 ASU00027.1
BDE75459.1
   
 PBI_PBS1_85   Takahashivirus PBS1 AST99907.1
BDE75273.1
   
 PBI_PBS1_85   Takahashivirus PBS1 AST99907.1
BDE75273.1
   
 PBI_PBS1_85   Takahashivirus PBS1 AST99907.1
BDE75273.1
   
 bacteriophage SPbeta N-acetylmuramoyl-L-alanine amidase (BlyA)   Thermus phage phi OH2 BAN62877.1    
 ORF   Thermus phage phi OH2 BAN62887.1    
 TwortDSMZ_055   Twortvirus twort QIW89060.1    
 TwortDSMZ_055   Twortvirus twort QIW89060.1    
 CES85_0495   [Ochrobactrum] quorumnocens A44 ASV87653.1    
 CES85_2611   [Ochrobactrum] quorumnocens A44 ASV86701.1    
 CES85_0955   [Ochrobactrum] quorumnocens A44 ASV87109.1    
 CM15mV42_0750   uncultured marine virus BCV01398.1    
 ORF   uncultured Mediterranean phage uvMED BAR34164.1    
 2F3_2   uncultured phage ASN72911.1    
 10F3_53   uncultured phage ASN70238.1    
 8F11_68   uncultured phage ASN68103.1    
 ORF   uncultured phage cr130_1 QOR57644.1    
 ORF   uncultured virus ASF00795.1    
 NVP1262O_04   Vibrio phage 1.262.O._10N.286.51.A9 AUR99090.1    
 endolysin   Virgibacillus phage Mimir87 QBP06957.1    
 endolysin   Virgibacillus phage Mimir87 QBP06957.1    
 endolysin   Virgibacillus phage Mimir87 QBP06957.1    
 pwc_35   Weissella phage PWc ARQ94569.1    
 JC221_244   Yersinia phage JC221 QFR55890.1    
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